Cancer Nanomedicine |
Autore | Hoskins Clare |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (510 p.) |
Soggetto topico | Technology: general issues |
Soggetto non controllato |
antibody drug conjugate (ADC)
PD-L1 tumor spheroid disruption immune modulation doxorubicin graphene oxide adsorption cathepsin D cathepsin L anti-metastatic enzyme cancer therapy nanoparticles targeted delivery system siRNA osteopontin mammary carcinoma mesenchymal stem cells (MSCs) TAT peptide PLGA paclitaxel nano-engineered MSCs orthotopic lung tumor model intracranial glioma immunotherapy CPMV viral nanoparticles in situ vaccine albumin nanoparticles microbubble ultrasound theranostics hepatocellular carcinoma VX2 tumor intra-arterial chemotherapy lung cancer nanomedicine clinical status cancer therapy breast cancer cell signaling active targeting passive targeting EPR effect oncogenes nanoparticle drug delivery ligand tumor targeting biodistribution Mesoporous silica nanoparticle drug delivery system target treatment lanthanide metal hyaluronic acid hyaluronidase drug combination everolimus dual-targeting magnetic nanoparticles monoclonal antibodies nanostructured lipid carrier platelet membrane biomimicry plasmonic photothermal therapy gold nanorods surgery bleeding dogs cats stimuli-responsive DOX SN38 CSCs single-walled carbon nanotubes chirality separation NASH drug-gene delivery near IR hyperspectral imaging plasmonics copper VEGF glioblastoma differentiated neuroblastoma peptidomimetics real-time quantitative polymerase chain reaction (qPCR) actin combinatorial therapy anticancer and antibacterial activity temoporfin drug-in-cyclodextrin-in-liposome hybrid nanoparticles multicellular tumor spheroids cyclodextrins photodynamic therapy article yet reasonably common within the subject discipline antitumor strategy biomimetic core–shell nanoparticles NK cell-derived exosomes folate receptor albumin nanoparticle microfluidic cabazitaxel polydopamine nanoparticles size cytotoxicity iron affinity FA-DABA-SMA self-assembly oncogenic proteins intracellular disruption folic receptor alpha pancreatic cancer parvifloron D albumin erlotinib photodynamic therapy lipid nanoparticles tumor vectorization verteporfin ovarian carcinomatosis spheroids integrin RGD peptide cancer diagnosis radiotherapy hyperthermia therapy biomimetic nanocarrier membrane-wrapped cancer targeted delivery photothermal therapy imaging cancer nanomedicine tumor microenvironment nano–bio interactions clinical translation magnetic nanowires magnetic hyperthermia magnetic actuation magnetic drug targeting titanate nanotubes gold nanoparticles vectorization colloidal stability docetaxel prostate cancer mangiferin anti-topoisomerase activity extracellular vesicles exosomes chemico-physical functionalization loading translational medicine nanotechnology: bioengineering anacardic acid mitoxantrone targeted drug delivery liposomes melanoma apoptosis ascorbic acid angiogenesis epithelial-to-mesenchymal transition hypoxia immunosuppression metabolism nanotherapeutics tumour microenvironment DNA origami liposome remote loading acute toxicity organoids magnetic silica-coated iron oxide nanochains photothermal treatment hyperthermia collagen cellular microenvironment lymphadenectomy magnetometer sentinel lymph node dissection SPION superparamagnetic iron oxide nanoparticles Vδ2 T cells zoledronic acid polymeric nanoconstruct anti-tumor immunity colorectal carcinoma β-cyclodextrin nanosponges BALB-neuT mice brain tumours glioma blood brain barrier polymeric nanoparticles PEGylation dioleoylphosphatidylethanolamine poly(hydroxyethyl acrylate-co-allyl methyl sulfide) copolymer folate oxidation-sensitive release cellular interaction in vitro anti-cancer activity triple negative breast cancer organotin mesoporous silica nanoparticles MDA-MB-231 theranostic nanomaterials nanobiotechnology molecular imaging nanosystems nanomicelles ovarian cancer tumour targeting chemotherapeutics riboflavin vitamin B2 nanomedicines secondary structure mixed micelle pH responsive targeted therapy anti-cancer shear stress flow in vitro therapeutics diagnostics Immunotherapy |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557114703321 |
Hoskins Clare | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Cytobiology of Human Prostate Cancer Cells and Its Clinical Applications |
Autore | Ishii Kenichiro |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (184 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
androgen receptor
docetaxel cabazitaxel castration-resistant prostate cancer chemotherapy P-glycoprotein EPI-002 splice variant prostate-specific antigen androgen deprivation therapy time to PSA nadir fibroblasts prostate cancer androgen sensitivity pirfenidone TGFβ1 G1 cell cycle arrest fibroblast growth factor fibroblast growth factor receptor obesity inflammation immune cells cytokine high-fat diet KIFC1 docetaxel resistance apoptosis CW069 Caveolin-1 TP53-regulated inhibitor of apoptosis 1 tumour stroma tumour microenvironment fibroblast CAF resistance radiotherapy CCL2 CCL22 CCL5 migration LSD1 epigenetics autophagy abiraterone enzalutamide testosterone castration resistant prostate cancer animal model diet fat in vitro in vivo mouse AKR1C3 hormone-naïve prostate cancer immunohistochemistry tissue microarray androgen receptor dependency fibroblast-dependent androgen receptor activation |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557116703321 |
Ishii Kenichiro | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Non-small Cell Lung Cancer: Current Therapies and New Targeted Treatments |
Autore | Uchino Junji |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (258 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
non-small cell lung cancer
previously treated patients phase I/II trial chemotherapy docetaxel S-1 immunotherapy rechallenge retrospective analysis pulmonary pleomorphic carcinoma prognostic factor glucose transporter 1 lung cancer multiple cancers metastasis sequencing mutation genomic diagnosis FDG-PET immune checkpoint inhibitor PD-1 prognosis RAD51B methylation PD-L1 expression predictive biomarker PD-1 blockade interstitial lung disease pulmonary fibrosis radiology and other imaging non-small-cell lung cancer epidermal growth factor receptor tyrosine kinase inhibitors TP53 mutations responsiveness targeted therapy network meta-analysis stage IIIA-N2 surgery immune checkpoint inhibitors biomarker nonsmall cell lung cancer HIP1R PD-L1 RUNX1 methylation survival EGFR-TKI T790M osimertinib immune-related adverse events endocrine disorders tumor-bearing patients PD-1 inhibitors PD-L1 inhibitors meta-analysis nivolumab Expanded Access Program real-world data daily practice prognostic factors NSCLC KRAS DNA polymerase beta platinum-based first-line adjuvant chemotherapy β-catenin lung neoplasms nucleotide-diphosphate kinase recurrence unresectable salvage surgery oligometastasis |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Non-small Cell Lung Cancer |
Record Nr. | UNINA-9910557489703321 |
Uchino Junji | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases |
Autore | Kwok Hang Fai |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (180 p.) |
Soggetto topico |
Humanities
Social interaction |
Soggetto non controllato |
DAPK1
SUMO SENP protein degradation post-translational modification amphibian Bowman-Birk inhibitor Tat peptide molecular cloning antifungal drug design protease inhibitor natural-based compound anticancer therapy lung cancer survivin apoptosis STAT3 colorectal cancer orientin cell cycle arrest Bcl-2 family proteins Astragalus membranaceus insulin PI3K AKT PPARγ PDX-1 Petasites japonicus Asteraceae lignan anti-inflammation NO PGE2 iNOS COX-2 molecular docking peptides kynurenines binding affinity μ-opioid receptor pharmacophore G-protein activation fucoidan PLGA docetaxel drug delivery system anticancer therapy/cancer treatment hIAPP amyloidogenesis insulin granules endoplasmic reticulum anionic lipids F23R variant β-sheet transitions β-cell cytotoxicity unfolded protein response pomegranate punicalagin tannins gingiva fibroblasts antioxidant wound healing branched-chain fatty acids Conidiobolus heterosporus peroxisome proliferator-activated receptor α lipid metabolism fatty acid oxidation hepatocyte |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557607403321 |
Kwok Hang Fai | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Oxidative Stress and Inflammation : From Mechanisms to Therapeutic Approaches |
Autore | Gambini Juan |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (234 p.) |
Soggetto topico | Public health & preventive medicine |
Soggetto non controllato |
diospyrin
lipopolysaccharide anti-inflammation macrophages nitric oxide cytokine calcium CHOP Fas p38 MAPK Astragalus mongholicus Bunge danazol telomere telomerase aging diabetic kidney disease oxidative stress redox imbalance hyperimmunized milk exercise inflammation intestinal permeability acute respiratory distress syndrome antiplatelet aspirin therapy gender membrane erythrocyte hydroperoxides biomarker DPPP DPH TMA cardiovascular disease data analysis precision-recall Mediterranean diet Oriental diet nutrition polyphenols microbiota health n-3 PUFAs endogenous antioxidants anti-inflammatory response cardiovascular diseases dry eye syndrome corneal damage tear lipidome 5-lipoxigenase leukotriene B4 prostaglandins dimethyl sulfoxide zileuton air pollution soot particulate matter lung inflammation functional groups microglia porcine liver decomposition product lysophospholipids mild cognitive impairment dementia neuroinflammation cytokines oxygen reactive species caloric restriction oxidative balance adiponectin plasma white adipose tissue experimental model anti-inflammatory diets inflammatory response chronic inflammation low grade chronic inflammation inflammatory models cyclophosphamide doxorubicin docetaxel paclitaxel |
ISBN | 3-0365-6024-6 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Oxidative Stress and Inflammation |
Record Nr. | UNINA-9910637783403321 |
Gambini Juan | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Peptides for Health Benefits 2019 : Volume 2 |
Autore | Hernández-Ledesma Blanca |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (342 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
antihypertensive peptides
functional food food-derived fermentation Chlorella sorokiniana in silico BIOPEP-UWM database proteomics bioactive peptides nano liquid chromatography tandem mass spectrometry (nanoLC-nanoESI MS/MS) apolipoprotein E amyloid fibrils Alzheimer's disease Αβ oligomer amyloid Aβ peptide glioma platelets antiproliferative assay conjugation docetaxel doxorubicin extra domain B fibronectin Fmoc/tBu peptide-drug conjugate prostate cancer solid-phase synthesis targeting acrylamide enteric nervous system galanin pig stomach formyl peptide receptors ligands diseases polymicrobial biofilms intragenic antimicrobial peptide Hs02 Pseudomonas aeruginosa Staphylococcus aureus osteostatin arthritis inflammation immune response cartilage destruction bone erosion collagen hydrolysis enzyme molecular weight sheepskin NF-κB dry-cured pork ham angiotensin I converting enzyme endothelial dysfunction molecular blind docking Lactoferricin B (Lfcin B) Histatin-5 antimicrobial peptides (AMPs) antifungal activity proteome microarray synergy temporin MRSA antimicrobial peptide human keratinocytes pseudin-2 antisepsis, peptide antibiotics neurotensin asthma T cells In situ tetramer staining MHC tetramer antigen-specific confocal microscopy fresh tissue velvet antler alcalase hydrolysate antioxidant peptide protection ability oxidative stress Crassostrea angulata pidotimod CXCR3 monocyte migration PI3K/Akt pathway T cell immunomodulant host defense peptides membrane activity copper piscidins Clostridioides difficile prolactin-releasing peptide GPR10 RF-amide peptides food intake regulation energy expenditure neuroprotection signaling gender differences dyslipidemia obesity hyperglycemia pulmonary emphysema endothelial progenitor cells angiogenic precursor cells pegylated glucagon-like peptide 1 and endothelial regeneration miiuy croaker (Miichthys miiuy) swim bladder FPYLRH antioxidant activity cytoprotective effect antimicrobial peptides antimicrobial resistance AMP identification and design biosynthesis mode of action physico-chemical properties therapeutic potential insects Cecropins Cec-analogs MDR infectious diseases airway inflammation non-atopic asthma hybrid peptide pro-inflammatory cytokines sPLA2 MDA database proteolysis SMILES code foods nutrition chronic diseases nutraceuticals peptide vaccine immune checkpoint inhibitor humanized mouse cancer antigen immune suppression vasoactive intestinal peptide VPAC1 receptor VPAC2 receptor rheumatic diseases inflammatory bowel disease central nervous system diseases type 1 diabetes Sjögren's syndrome biomarkers human antimicrobial peptides defensins cathelicidins anti-inflammatory pro-inflammatory peptide combinatorial library library design screening mutagenesis prolyl-hydroxyproline (Pro-Hyp) hydroxyprolyl-glycine (Hyp-Gly) collagen peptide fibroblasts fetal bovine serum (FBS) AMD CNV VEGFR1 multimeric peptides oral delivery colorectal cancer cancer stem cells chemoprevention bioactive peptide lunasin ACE-inhibitory activity whey peptides molecular docking hypertension antibiotic resistance cystic fibrosis cryptides anti-biofilm peptides synergistic effects |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Peptides for Health Benefits 2019 |
Record Nr. | UNINA-9910557492903321 |
Hernández-Ledesma Blanca | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Peptides for Health Benefits 2019 : Volume 1 |
Autore | Hernández-Ledesma Blanca |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (340 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
antihypertensive peptides
functional food food-derived fermentation Chlorella sorokiniana in silico BIOPEP-UWM database proteomics bioactive peptides nano liquid chromatography tandem mass spectrometry (nanoLC-nanoESI MS/MS) apolipoprotein E amyloid fibrils Alzheimer's disease Αβ oligomer amyloid Aβ peptide glioma platelets antiproliferative assay conjugation docetaxel doxorubicin extra domain B fibronectin Fmoc/tBu peptide-drug conjugate prostate cancer solid-phase synthesis targeting acrylamide enteric nervous system galanin pig stomach formyl peptide receptors ligands diseases polymicrobial biofilms intragenic antimicrobial peptide Hs02 Pseudomonas aeruginosa Staphylococcus aureus osteostatin arthritis inflammation immune response cartilage destruction bone erosion collagen hydrolysis enzyme molecular weight sheepskin NF-κB dry-cured pork ham angiotensin I converting enzyme endothelial dysfunction molecular blind docking Lactoferricin B (Lfcin B) Histatin-5 antimicrobial peptides (AMPs) antifungal activity proteome microarray synergy temporin MRSA antimicrobial peptide human keratinocytes pseudin-2 antisepsis, peptide antibiotics neurotensin asthma T cells In situ tetramer staining MHC tetramer antigen-specific confocal microscopy fresh tissue velvet antler alcalase hydrolysate antioxidant peptide protection ability oxidative stress Crassostrea angulata pidotimod CXCR3 monocyte migration PI3K/Akt pathway T cell immunomodulant host defense peptides membrane activity copper piscidins Clostridioides difficile prolactin-releasing peptide GPR10 RF-amide peptides food intake regulation energy expenditure neuroprotection signaling gender differences dyslipidemia obesity hyperglycemia pulmonary emphysema endothelial progenitor cells angiogenic precursor cells pegylated glucagon-like peptide 1 and endothelial regeneration miiuy croaker (Miichthys miiuy) swim bladder FPYLRH antioxidant activity cytoprotective effect antimicrobial peptides antimicrobial resistance AMP identification and design biosynthesis mode of action physico-chemical properties therapeutic potential insects Cecropins Cec-analogs MDR infectious diseases airway inflammation non-atopic asthma hybrid peptide pro-inflammatory cytokines sPLA2 MDA database proteolysis SMILES code foods nutrition chronic diseases nutraceuticals peptide vaccine immune checkpoint inhibitor humanized mouse cancer antigen immune suppression vasoactive intestinal peptide VPAC1 receptor VPAC2 receptor rheumatic diseases inflammatory bowel disease central nervous system diseases type 1 diabetes Sjögren's syndrome biomarkers human antimicrobial peptides defensins cathelicidins anti-inflammatory pro-inflammatory peptide combinatorial library library design screening mutagenesis prolyl-hydroxyproline (Pro-Hyp) hydroxyprolyl-glycine (Hyp-Gly) collagen peptide fibroblasts fetal bovine serum (FBS) AMD CNV VEGFR1 multimeric peptides oral delivery colorectal cancer cancer stem cells chemoprevention bioactive peptide lunasin ACE-inhibitory activity whey peptides molecular docking hypertension antibiotic resistance cystic fibrosis cryptides anti-biofilm peptides synergistic effects |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Peptides for Health Benefits 2019 |
Record Nr. | UNINA-9910557631703321 |
Hernández-Ledesma Blanca | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Urological Cancer 2021 |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (328 pages) |
Soggetto topico |
Research
Chemistry |
Soggetto non controllato |
bladder cancer
radiotherapy radiosensitisation molecular subtypes preclinical studies bladder cancer cell lines latent cancer prostate cancer autopsy prognostic index prediction model mortality screening trial renal cell carcinoma PD-1 PD-L1 biomarkers immune checkpoint inhibitors prostatic neoplasms positron-emission tomography decision making tumor thrombus metastasectomy postoperative complications oncological outcomes radical cystectomy AHNAK2 prognosis dog comparative oncology inflammation prostatic atrophy preneoplastic lesion biomarker urine machine learning TRIPOD liquid biopsy glutaminase immunohistochemistry in situ methods prostate PSMA-RLT 177Lu-PSMA PSA mCRPC urinary bladder neoplasms Bacillus Calmette-Guérin (BCG) immunotherapy divergent differentiation variant morphology survival stereotactic body radiotherapy frail patients cancer metastasis genomic analysis microenvironment tumor ecology game theory fluorescence confocal microscopy prostate biopsy ablation margins focal therapy sphingosine 1-phosphate receptor 1 bladder carcinoma cell migration epithelial-mesenchymal transition FTY-720 OIP5 papillary renal cell carcinoma PLK1 tumorigenesis therapy image-guided magnetic resonance imaging ultrasonography biopsy abiraterone enzalutamide docetaxel novel hormonal therapies comparative effectiveness real-world treatment pattern metastatic prostate cancer epiplakin diagnosis advanced urothelial carcinoma immune checkpoint inhibitor prognostic tumour mutational board genomic signatures ctDNA inflammatory indices urothelial carcinoma frailty prognostic factor psoas muscle Hounsfield units |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910576872803321 |
MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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