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ABC Transporters in Human Diseases
| ABC Transporters in Human Diseases |
| Autore | Falguières Thomas |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (494 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
5' untranslated region
AAV ABC ABC (ATP-binding cassette) transporters ABC transporter ABC transporters ABCA subfamily ABCA7 ABCB1 ABCB11 ABCB4 ABCC2 ABCC6 ABCG2 ABCG2 genotype ABCG5 ABCG5/G8 ABCG8 adrenoleukodystrophy Alzheimer's disease amyloid-beta anticancer antifungal resistance atherosclerosis ATP-binding cassette transporter ATP-binding cassette transporter A1 (ABCA1) Aβ peptides BCRP beta-amyloid bile salts bile secretion bioinformatics blood-brain barrier breast cancer BRIC BSEP calcification cAMP cancer cellular ATP efflux chaperones cholesterol cholesterol homeostasis cis-acting elements clinico-genetic analysis competitive allele-specific PCR disease-free survival drug action drug transport dyslipidemia early-onset gout erlotinib ethnic specificity fatty acids functional divergence gall stone gene therapy generalized arterial calcification of infancy genetic variations gout HDL-C homology modeling hyperuricemia intracellular traffic intrahepatic cholestasis invasion MDR3 mechanism mechanism of action membrane protein microparticles migration molecular partners MRP1 MRP4 multidrug resistance multidrug transporter mutagenesis mutations n/a neuron next-generation sequencing NT5E P-glycoprotein peroxisome PET PFIC PFIC2 phagocytosis phosphatidylcholine phytosterol polar relay polymorphisms precision medicine proliferation pseudoxanthoma elasticum Pseudoxanthoma elasticum (PXE) pyrophosphate RAB GTPase rare variant regulatory extension regulatory insertion reverse cholesterol transport Roma serum uric acid single nucleotide polymorphism sitosterolemia SK-N-SH SNP SUA-lowering therapy substrate-binding site tariquidar taxol therapies therapy response TNAP trafficking transport transporter type 2 diabetes urate urate transporter uric acid xenosterol yeast |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674029103321 |
Falguières Thomas
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Treatment Strategies and Survival Outcomes in Breast Cancer
| Treatment Strategies and Survival Outcomes in Breast Cancer |
| Autore | Cheung Kwok-Leung |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (264 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
abemaciclib
advanced breast cancer anthracycline resistance antihormone therapy APOBEC3B aromatase inhibitors ATM basal-like breast cancer biomarker BRCA breast cancer Breast Cancer breast cancer survivors breast-conserving therapy cancer treatment cell-free DNA CHEK2 chemotherapy circulating tumor cells cMet colorectal cancer comparative effectiveness contralateral breast cancer contralateral prophylactic mastectomy cyclin E disease-free survival ductal carcinoma in situ Endocrine therapy ERCC1 exercise characteristics family history fulvestrant gene expression geriatric oncology HDAC5 inhibitors HER2 c-erbB2 HER2/neu histone deacetylase incidence infiltrating breast cancer invasive breast cancer lactate dehydrogenase lapatinib LDH liquid biopsy LKB1 LMK-235 lymph-node ratio mammography screening mastectomy metastatic metastatic breast cancer Metformin monitoring metastatic breast cancer mutation carriers n/a NCDB next-generation sequencing older patients Older women outcome overdiagnosis PALB2 palbociclib pertuzumab physical activity physical function PIK3CA prognosis radiotherapy relative survival ribociclib SEER serum biomarker social well-being Src kinase stage IV survival T-DM1 taxane sensitivity trastuzumab tumor biology young women zero-inflated Poisson regression model |
| ISBN | 3-03928-759-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404084403321 |
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Cheung Kwok-Leung
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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