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Aging and Age-related Disorders: From Molecular Mechanisms to Therapies
| Aging and Age-related Disorders: From Molecular Mechanisms to Therapies |
| Autore | Titorenko Vladimir |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (322 p.) |
| Soggetto non controllato |
advanced glycated end products
microRNAs differentiation transcription skin absorption cellular quiescence lifespan longevity genes protein kinases self-renewal circadian blood-brain barrier aging-related disorders sirtuin-1 inflammation arterial aging reactive oxygen species electron microscopy reconstructed human skin rejuvenation low-dose fluvastatin and valsartan combination inflammaging hematopoietic stem cell aging cell cycle mitochondria ribose the nervous system nanomedicine proteostasis adult stem cells immunosenescence cell signaling mechanisms of quiescence maintenance metabolism aging melatonin diabetes mechanisms of quiescence entry and exit Drosophila melanogaster GSK3 (glycogen synthase kinase 3) |
| ISBN | 3-03921-356-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Aging and Age-related Disorders |
| Record Nr. | UNINA-9910367567903321 |
Titorenko Vladimir
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anti-inflammatory Activity of Plant Polyphenols 2.0
| Anti-inflammatory Activity of Plant Polyphenols 2.0 |
| Autore | Dell'Agli Mario |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (120 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
flavonoids
inflammation p53 cancer prevention Nrf2 pathway anti-oxidant verbascoside polyphenols insulin-producing cells diabetes UPR oxidative stress ER-stress PERK anti-inflammatory mitochondria antioxidants marine algae anti-viral activity mechanism of action Antirhea borbonica kidney fibrosis caffeic acid antioxidant enzymes DESI-imaging curcumin glioblastoma cells radiation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576880903321 |
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Dell'Agli Mario
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antioxidant Activity of Polyphenolic Plant Extracts
| Antioxidant Activity of Polyphenolic Plant Extracts |
| Autore | Stagos Dimitrios |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (388 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
green leafy vegetables
effect of cooking polyphenols antioxidant activity Averrhoa bilimbi Oxalidaceae DPPH xanthine oxidase LC-QTOF-MS/MS molecular docking tentative bioactive constituents Dialium indum exocarp seed antioxidant phenolic acids amino acids GC-MS analysis AGN FIR phenolic flavonoid antioxidant capacity antimicrobial activity polyphenol compounds bixin rosemary extracts method validation HPLC food matrices fruit vinegar phenolics organic acid Ladastacho characterisation properties HPLC/ESI-MS HS-SPME/GC-MS beneficial use antimicrobial hydroxytyrosol rosemary pomegranate fish volatile compounds Rosa canina Rosa sempervivens Pyrocantha coccinea antioxidants endothelial cells glutathione almond skins bioavailability waste by-products flavonoids oxidative stress human reactive oxygen species proinflammatory cytokines Alzheimer's disease cornelian cherry anthocyanins gastrointestinal digestion Opuntia ficus-indica cladode antibiofilm activity olive Olea europaea anthocyanin cyanidin 3-glucoside cyanidin 3-rutinoside oxygen radical absorbance capacity (ORAC) high performance liquid chromatography mass spectrometry (HPLC-MS) tea Camellia sinensis polyphenol catechin caffeine theaflavine insulin resistance diabetes olive oil phenols antidiabetic myrtle ultrasound-assisted extraction phenolic compounds liquid chromatography analysis mass spectrometry mulberry (Morus nigra Morus alba) simple sugars organic acids phenol compounds high performance liquid chromatography/diode array detector/mass spectrometry anthocyanins anti-inflammatory activity extraction central composite design optimization P. officinalis phytochemicals cytotoxicity α-amylase inhibition red-osier dogwood antioxidative effect H2O2 transepithelial resistance (TEER) Caco-2 cells Rubus idaeus L. HPLC-ESI-HR-qTOF-MS/MS antioxidant activities digestive enzymes inhibitors molecular docking analysis olive mill wastewater encapsulation maltodextrin whey protein gelatin spray drying diabetes mellitus Lamiaceae alpha-glucosidase alpha-amylase Salvia africana-lutea terpenoids cape floristic region |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557728403321 |
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Stagos Dimitrios
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antioxidants in Foods
| Antioxidants in Foods |
| Autore | Seiquer Isabel |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (418 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
green tea extract
food processing tannase ultrasound antioxidant activity liver injury acclimatisation antioxidant defences chlorophyll fluorescence in vitro culture peroxidase stevia plants 7S basic globulins anti-inflammatory protein antioxidant protein cytokines glutathione iNOS nitric oxide oxidative stress sweet lupins group home-cooking extra virgin olive oil UPLC-ESI-QqQ-MS/MS healthy cooking Mediterranean diet phenolic compounds bioactive compounds functional pasta gluten-free pasta bioaccessibility bioavailability whole grain composite flour legumes food by-products avocados (Persea americana Mill.) low temperatures plastochromanol-8 tocotrienols tocopherols tocochromanols kombucha tea fermentation antioxidant flavonoids polyphenols ascorbic acid chlorophyll and carotenoid content biodiversity Capsicum annuum L. β-carotene statistical analysis rye bread microencapsulation phenolics in vitro relative bioaccessibility lipoxygenase cyclooxygenase acetylcholinesterase biological activity lycopene antioxidants cancer diabetes cardiovascular diseases skin disorders free radicals spectrophotometer limitations chemical reactions colorimetry anthraquinone free radical scavenging inflammatory cytokines apoptosis Rumex crispus skins seeds Vitis vinifera cyclic voltammetry anthocyanin metabolites cardioprotection hepatoprotection nephroprotection neuroprotection antioxidant peptides element of pork carcasses spectrometric analysis ascorbate ascorbate-glutathione cycle capsaicin catalase dihydrocapsaicin NADP-dehydrogenases superoxide dismutase red cabbage in vitro gastrointestinal digestion acid-resistant capsule UHPLC-Q-Orbitrap HRMS apples reducing and chelating capacity HPLC-DAD-MS/MS Dillenia indica heme oxygenase 1 (HO-1) nuclear factor erythroid 2-related factor 2 (Nrf2) RAW 264.7 cells apo-carotenals bone osteoclasts NFκB synergy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557728503321 |
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Seiquer Isabel
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Benefits of Resveratrol Supplementation
| Benefits of Resveratrol Supplementation |
| Autore | Fernandez-Quintela Alfredo |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto non controllato |
polyphenols
?-viniferin leptin resistance p53 kidney energy restriction grape powder extract cytokines phosphorylation obesity energy metabolism metabolic pathways endothelial function polyol pathway antioxidant caloric restriction rat adipose tissue microparticles pathways angiotensin converting enzyme 2 resistance esRAGE interleukins metabolic syndrome dissolution rate thermogenesis streptozotocin bioavailability solubility metabolism renin-angiotensin system microbiota Sirt-1 magnesium dihydroxide hypertrophy metabolic diseases physiological adaption red wine extract lens distribution MTA1 sirtuin inflammation cardiac function rats cisplatin resveratrol mitochondria breast cancer ischemia-reperfusion cardiovascular metabolites gut microbiota prostate cancer performance type 2 diabetes cafeteria diet high-fat high-sucrose diet resistance exercise aging diabetes oxidative stress |
| ISBN | 3-03921-276-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346854603321 |
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Fernandez-Quintela Alfredo
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bibliometric Studies and Worldwide Research Trends on Global Health
| Bibliometric Studies and Worldwide Research Trends on Global Health |
| Autore | Manzano Agugliaro Francisco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (326 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
social networks
health young people bibliometric study scientometrics obesity interventions children youths pediatrics reclaimed water advanced oxidation process microorganisms concern emergent contaminant worldwide content analysis text mining diabetes QOL artificial intelligence machine learning bibliometric LDA HIV/AIDS quality of life global health public health scientometric study knowledge map visualization analysis CiteSpace COPD QoL medicinal plants drugs worldwide research bibliometrics traditional medicine asthma HRQoL Scival patents Spain Research and Development (R& D) social returns COVID-19 biomechanics musculoskeletal disorders RULA ergonomics applications climate change infectious diseases bibliometric analysis co-word analysis biclustering strategic diagram academic performance citation network motivation microplastics network analysis VOSviewer software research hotspots pulmonary disease musculoskeletal risks wastewater treatment |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557629603321 |
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Manzano Agugliaro Francisco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioinformatics Applications Based On Machine Learning
| Bioinformatics Applications Based On Machine Learning |
| Autore | Chamoso Pablo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (206 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
machine learning
metagenomics bioinformatics CTX-M data mining cluster clinical implications diabetes epidemiology forecast PART Decision table Weka real-life patients regression ear detection computer vision convolutional neural network image recognition video analysis gene clustering swarm intelligence biological functions detection informative genes fuel cell hydrogen energy intelligent systems hybrid systems Artificial Neural Networks power management Machine Learning personality assessment gradient boosting Affective Computing transposable elements metrics deep learning detection classification mitochondrial protein bi-directional LSTM plasmodium falciparum Particle Swarm Optimization Harmony Search parameter estimation Arabidopsis thaliana clinical data feature selection genetic programming evolutionary computation dynamic models evolutionary computing derivative-free optimization metabolism glycolysis yeast |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674055503321 |
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Chamoso Pablo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomarkers for Diagnosis, Complications and Therapy Effects in Civilization Diseases Management
| Biomarkers for Diagnosis, Complications and Therapy Effects in Civilization Diseases Management |
| Autore | Komosinska-Vassev Katarzyna |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (208 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
pharmacogenomics
NGS variants personalized medicine FSHR personalized drug therapy hedgehog-interacting protein impaired fasting glucose impaired glucose tolerance newly diagnosed diabetes normal glucose tolerance inflammatory bowel disease ulcerative colitis Crohn’s disease extracellular matrix components hyaluronan inflammatory bowel diseases (IBD) Crohn’s disease (CD) ulcerative colitis (UC) sulfated glycosaminoglycans (sGAG) hyaluronan (HA) soluble part of syndecan-1 (sCD138) microRNA cardiovascular disease diabetes mortality antiplatelet therapy platelet reactivity Let-7e miR-126 miR-223 miR-125a-3p CCL11 CCL24 CCL26 CCR3 CRC adiponectin adipokines rheumatology obesity overweight case control study rheumatoid arthritis TNF-α inhibitors bone turnover markers PINP PICP NTX-I CTX-I RANKL/OPG ovarian cancer interleukin 21 interleukin 22 lymphocytes macrophages dendritic cells innate lymphoid cells breast cancer extracellular matrix proteins tumorigenesis tumor microenvironment |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566458203321 |
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Komosinska-Vassev Katarzyna
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomaterial-Related Infections
| Biomaterial-Related Infections |
| Autore | Rodrigues Célia F |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Candida
biofilms diabetes medical devices candidiasis metabolic disorder hyperglycemia infection Candida glabrata candidemia echinocandins resistance micafungin caspofungin in vivo titanium dioxide nanotubes autoclaving titanium alloy biocompatibility wettability mechanical properties silver nanoparticles titanium dioxide nanotubes silver ions release biointegration antimicrobial activity polyethylene terephthalate PET electrospinning nanofibers antimicrobial agents Taguchi method antimicrobial efficiency cold atmospheric-pressure plasma jet (CAPJ) Escherichia coli DNA double-strand breaks scanning electron microscopy Ti6Al4V implants anodization process XPS genotoxicity assessment anti-inflammatory properties oral biofilm infection control Streptococcus mutans Candida spp natural compounds antimicrobial resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557289503321 |
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Rodrigues Célia F
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing
| Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing |
| Autore | Pörtner Ralf |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (226 p.) |
| Soggetto topico |
Technology: general issues
History of engineering & technology |
| Soggetto non controllato |
clonal cell population
phenotypic diversity inoculum train uncertainty-based cell culture model biopharmaceutical manufacturing Escherichia coli hybrid modeling machine learning model-assisted DoE quality by design upstream bioprocessing surface plasmon resonance (SPR) bioprocess monitoring biosensor quality by design (QbD) process analytical technology (PAT) biotherapeutics production vaccines production CHO DP-12 computational fluid dynamics bioreactor characterization hydrodynamic gradients process development critical shear stress Kolmogorov length scale operational space sensors cell culture spectroscopy PAT smart biomanufacturing soft-sensor Adeno-associated virus transfection PEI continuous gene therapy microcarriers bioreactor transient expression spheroid strength β-cells diabetes shear stress-guided production hydrodynamic stress Gaussian processes Bayes optimization Pareto optimization multi-objective seed train Chinese hamster ovary cells cryopreservation monoclonal antibodies N−1 perfusion process intensification upstream processing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595072803321 |
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Pörtner Ralf
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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