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BCR Signaling and B Cell Activation
| BCR Signaling and B Cell Activation |
| Autore | Liu Wanli |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (159 p.) |
| Soggetto topico |
Medicine
Immunology |
| Soggetto non controllato |
B cell
B cell receptor (BCR) B cell activation antibody antigen imaging co-receptor cytoskeleton |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557429203321 |
Liu Wanli
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cell-Cell and Cell-Matrix Adhesion in Immunobiology and Cancer
| Cell-Cell and Cell-Matrix Adhesion in Immunobiology and Cancer |
| Autore | Murai Toshiyuki |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (138 p.) |
| Soggetto topico |
Medicine
Immunology |
| Soggetto non controllato |
cell adhesion molecule
extracellular matrix immune system cancer progression cytoskeleton cell dynamics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557723603321 |
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Murai Toshiyuki
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Emerging Functions of Septins
| Emerging Functions of Septins |
| Autore | Manoj B. Menon |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 electronic resource (126 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
mutation
cytoskeleton cytokinesis budding SOCE septin cancer GTPase yeast Cilia |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910261133203321 |
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Manoj B. Menon
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Genetic Conditions Affecting the Skeleton : Congenital, Idiopathic Scoliosis and Arthrogryposis
| Genetic Conditions Affecting the Skeleton : Congenital, Idiopathic Scoliosis and Arthrogryposis |
| Autore | Giampietro Philip |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (172 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Genetics (non-medical) |
| Soggetto non controllato |
spinal curvatures
scoliosis idiopathic DNA methylation pyrosequencing estrogen receptor 1 ESR1 scoliosis progression adolescent idiopathic scoliosis idiopathic scoliosis exome sequencing spine polygenic variants musculoskeletal disease cytoskeleton extracellular matrix contracture arthrogryposis congenital POC5 cilia genetics spine deformity genetic predisposition complex trait model animal genome wide association study genetic linkage study Amyoplasia DECIPHER (DatabasE of genomiC variation and Phenotype in Humans using Ensemble Resources) CNV (copy number variant) DA (distal arthrogryposis) IPA (ingenuity pathway analysis) HPO (human phenotype ontology) akinesia MYOD IGF2 FGFR1 (Fibroblast growth factor receptor 1) genetic variations congenital scoliosis monozygotic twin epigenome-wide association study bone discordant curve severity differentially methylated region congenital vertebral malformation copy number variant CNV CHRNG distal arthrogryposis type 8 Escobar multiple pterygium syndrome MYH3 protein tyrosine kinase 7 (PTK7) whole exome sequencing |
| ISBN | 3-0365-5976-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Genetic Conditions Affecting the Skeleton |
| Record Nr. | UNINA-9910639995403321 |
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Giampietro Philip
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Intraocular Pressure and Ocular Hypertension
| Intraocular Pressure and Ocular Hypertension |
| Autore | Brusini Paolo |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
intraocular pressure
serum calcium female ab interno trabeculotomy glaucoma incision in the Schlemm's canal in degrees post-surgical complication neuroretinal rim reversal Bruch's membrane opening-minimum rim width trabeculectomy refractive error neuroretina myopia intraocular pressure (IOP) tonometry Goldmann applanation tonometer (GAT) central corneal thickness (CCT) ocular hypertension higher-order aberrations Kahook Dual Blade age central corneal thickness Goldmann Applanation tonometer non-contact tonometer rebound tonometer iCare open angle glaucoma (OAG) Schlemm's canal viscodilation OMNI viscosurgical system minimally invasive glaucoma surgeries (MIGS) trabeculotomy cataract extraction aqueous humor GDF15 serum intravitreal injection anti-VEGF agents trabecular meshwork Matrigel 3D culture outflow cytoskeleton rho-kinase inhibitor prostaglandin analog childhood glaucoma aphakia pseudophakia cataract surgery lensectomy management (or therapy) glaucoma drainage device cyclodestruction corneal biomechanics ocular response analyzer ORA corneal hysteresis non-penetrating deep sclerectomy Esnoper V-2000 implant glucocorticoids safety profile intranasal administration inhaled administration systemic administration steroid response canaloplasty non-perforating surgical procedures pseudoexfoliation glaucoma (PEXG) Schlemm's canal phase-sensitive optical coherent tomography pulsatile motion IOP fluctuation primary open-angle glaucoma intraocular pressure measurement iCare tonometry Perkins tonometry standardized anaesthesia corneal thickness progression risk stratification XEN GelStent corneal resistance factor open-angle glaucoma laser treatment dropless treatment thyroid-associated ophthalmopathy extraocular muscle magnetic resonance imaging T2 relaxation time |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595078903321 |
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Brusini Paolo
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
apoptosis
fucoidan hepatocellular carcinoma reactive oxygen species 3-alkylpyridinium polymers nicotine nicotinic acetylcholine receptor non-small cell lung carcinoma melanoma sinulariolide proteomic mitochondria caspase cascade marine fungus sediment anthranilic acid Penicillium paneum cytotoxicity dibromotyrosine mitochondrial dysfunction oxidative stress topoisomerase epigonal organ bonnethead shark Jurkat tumor cell line hippuristanol PEL AP-1 STAT3 Akt colorectal cancer marine mollusc brominated indoles shrimp chemoprevention fatty acids carotenoids cancer nanoparticle osteosarcoma lung metastasis elisidepsin lipid rafts hydroxylated lipids fatty acid 2-hydroxylase cooperative binding membrane permeabilization marine organisms polysaccharides anticancer anticarcinogenic mechanisms of action fumigaclavine C anti-proliferation mitochondrial pathway anti-cancer anti-proliferative carotenoid cell cycle arrest fucoxanthin azoxymethane bioactive natural product isatin in vivo model Marthasterias glacialis L. palmitic acid ER-stress CHOP Antibody Drug Conjugates (ADCs) marine antitumor agents clinical trials approved antitumor agents AD0157 angiogenesis marine drug pyrrolidinedione secondary metabolites cancer preventive chemopreventive trabectedin plitidepsin tumor-associated macrophages tumor microenvironment preclinical anticancer immunity antiangiogenesis fascaplysin cyclin-dependent kinase small cell lung cancer camptothecin poly(ADP-ribose)-polymerase inhibitor breast cancer seaweed therapeutic compounds autophagy marine drugs autophagy inhibitors autophagy inducers macrolide programmed cell death energy stress araguspongine C c-Met HER2 gemcitabine pazopanib phase I safety soft tissue sarcoma pachastrissamine jaspine B carbocyclic analogue sphingosine kinase inhibitor molecular modeling ET-743 DNA minor groove binder soft tissue sarcoma chemotherapy bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) anti-metastatic activity cell adhesion β1-integrin FAK BEL-7402 cell triterpene glycosides sea cucumbers antitumor activities arrest of cell cycle antibacterial marangucyclines deep-sea Streptomyces sp. SCSIO 11594 LS-1 SNU-C5/5-FU TGF-β signaling carcinoembryonic antigen kalkitoxin Moorea producens mitochondria toxin VEGF angiogenesis inhibitor hypoxia-inducible factor-1 HIF-1 Lyngbya majuscula marine metabolites SZ-685C nonfunctioning pituitary adenomas Ecklonia cava phlorotannins dieckol migration sipholenol A ABC transporter multidrug resistance P-gp/ABCB1 BCRP/ABCG2 MRP1/ABCC1 marine natural products glioblastoma xyloketal B proliferation TRPM7 marine compound ribosomal protein genes snoRNA FAU RPS30 SNORA62 evolution Porifera Penicillium brevicompactum Brevianamide Mycochromenic acid derivative antifouling Caribbean sponge plakortide endoperoxide leukemia multi-drug resistant leukemia Sarcophyton ehrenbergi soft coral terpenes cembranoids cytotoxic activity molecular docking uveal melanoma oxidative stress virtual screening Topo I inhibitor low toxic natural product Ulva fasciata selenium-containing polysaccharide-protein complex pseudopterosin NF-κB p65 inflammation cytokine release IL-6 TNFα MCP-1 glucocorticoid receptor paulomycins Micromonospora antitumor Cantabrian Sea-derived actinobacteria puupehenones sponges antiangiogenic antitumoral porifera/sponge cancer genes molecular oncology bromophenol molecular mechanisms cell cycle PI3K/Akt p38/ERK ROS human lung cancer glycosaminoglycans antiproliferative heparan sulphate gliotoxin NSCLC adriamycin resistance Sepia ink polysaccharides antitumour chemosensitization anticoagulation sea anemone drug discovery endothelial cells RGD motif kunitz type inhibitor prostate cancer antioxidant natural marine compounds marine biotechnology microalgae marine sponges Aeroplysinin Isofistularin pheochromocytoma and paraganglioma metastasis cancer progression cell adhesion molecules integrin β1 hypoxia phycocyanin non-small cell lung cancer NF-κB signaling marine-derived drugs bioanalysis chromatography manzamine A epithelial-mesenchymal transition lung cancer circulating tumor cells signal transduction cisplatin Lampetra morii buccal gland cystatin F anti-angiogenesis cystatin superfamily Antimicrobial peptide (AMP) Tilapia piscidin 4 (TP4) non-small cell lung cancer (NSCLC) itampolin A FBDD p38α novel inhibitor tetracenomycin X cyclin D1 proteasomal degradation p38 c-JUN λ-carrageenan heparanase anticoagulant depolymerisation cell migration Aspergillus naphthopyrones endophytic fungus Leathesia nana mangrove-derived actinomycete ansamycins divergolides apoptosis-inducing activity actinomycin EMT invasion low molecular weight fucoidan extract N-Ras neuroblastoma-rat sarcoma Cancer programmed cell death-ligand 1 programmed cell death-ligand 2 human sarcoma cell line (HT1080 cells) human normal diploid fibroblast (TIG-1 cells) chimera chemical conjugation anticancer agent hybridization α9-nicotinic acetylcholine receptors (nAChRs) breast cancer cells αO-conotoxin GeXIVA targeted therapy gorgonian Leptogorgia humulane sesquiterpenoids anticancer activity 12-deacetyl-12-epi-scalaradial HeLa cells Nur77 MAPK/ERK pathway Mycalin A C15 acetogenins synthetic analogues antiproliferative activity A375 and HeLa cell lines polyoxygenated steroids sponge Haliclona gracilis Thalassia testudinum thalassiolin B polyphenols CYP1A1 benzo[a]pyrene JNK1/2 natural products synergism A549 cells cytoskeleton P2X7 receptor pollution anti-angiogenic gene expression HSP90 inhibitor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Psychiatry
| Molecular Psychiatry |
| Autore | Rein Theo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Mental health services |
| Soggetto non controllato |
cardiovascular disease
cell adhesion molecules immunology inflammation nervous system schizophrenia bipolar disorder major depressive disorder DNA methylation response variability antipsychotics drug design multi-target drugs polypharmacology multi-task learning machine learning biomarker discovery psychiatry serotonin 5-HT 4 receptor 5-HT4R depression mood disorder expression Alzheimer's disease cognition Parkinson's disease forced swimming Roman rat lines stress hippocampus BDNF trkB PSA-NCAM western blot immunohistochemistry general cognitive function intelligence GWAS genetic correlation childhood-onset schizophrenia (COS) induced pluripotent stem cell (iPSC) copy number variation (CNV) early neurodevelopment neuronal differentiation synapse dendritic arborization miRNAs stress physiology cytoskeleton actin dynamics DRR1 TU3A FAM107A acid sphingomyelinase alcohol dependence liver enzymes sphingolipid metabolism withdrawal Hsp90 GR stress response steroid hormones molecular chaperones psychiatric disease circadian rhythms FKBP51 FKBP52 CyP40 PP5 DISC1 neurodevelopment CRMP-2 proteomics antidepressant treatment HPA axis gene expression FKBP5 sleep sleep EEG biomarkers antidepressants cordance gender sex difference antidepressant rapid-acting Ketamine endocrinology (2R,6R)-Hydroxynorketamine electroconvulsive therapy basic-helix-loop-helix brain coactivator glucocorticoids mineralocorticoid receptor knockout transcription biology dopaminergic gene polymorphisms affective temperament obesity alpha-synuclein SNCA major depression Hamilton Scale of Depression chemokines neuroinflammation social defeat Immune response T cells susceptibility resilience Treg cells Th17 cells behavior PPARγ |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557793503321 |
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Rein Theo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant Development and Organogenesis: From Basic Principles to Applied Research
| Plant Development and Organogenesis: From Basic Principles to Applied Research |
| Autore | Frugis Giovanna |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (246 p.) |
| Soggetto non controllato |
HD-Zip transcription factors
Plant in vitro cultures plant breeding recalcitrant species CLV wounding semi-dwarf photoreceptors Arabidopsis thaliana root development morphogenesis embryogenesis cytokinin auxin conjugation molecular marker Development boundaries translational research proline biosynthesis Brassicaceae meristem formation phytohormones stem cells meristem cytoskeleton hydrogen peroxide ligule genetic improvement tree phase change Rht18 hairy roots WUS GRETCHEN HAGEN 3 (GH3) IAA-amido synthase group II photoperiod linkage map SAM ground tissue signaling differentiation protoxylem ambient temperature gibberellins molecular regulation proximodistal patterning wheat-rye hybrids RolD somatic cell selection flowering time plant development and organogenesis grass root wheat crop productivity genetic transformation regulatory networks light environment rol genes root plasticity morphogenic stem apical meristem auxin shoot meristem Arabidopsis organogenesis transformation Vasculature Organogenesis radial patterning plant development reduced height root apical meristem Asteraceae vernalization KNOX transcription factors locule plant cell and tissue culture Agrobacterium rhizogenes genes of reproductive isolation cell wall lateral root cap CLE auxin minimum age |
| ISBN | 3-03928-127-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Plant Development and Organogenesis |
| Record Nr. | UNINA-9910372782903321 |
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Frugis Giovanna
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Structure, Activity, and Function of Protein Methyltransferases
| Structure, Activity, and Function of Protein Methyltransferases |
| Autore | Jeltsch Albert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (292 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
protein lysine methylation
H3K9 methylation PKMT enzyme specificity enzyme regulation heterochromatin protein post-translational modification NSD3 WHSC1L1 structure and function protein arginine methylation PRMT7 epigenetics cancer immunity pluripotency SETDB1 methyltransferase schizophrenia Huntington's disease Rett syndrome Prader-Willi syndrome congenital heart diseases inflammatory bowel disease MLL2 structure H3K4me3 chromatin regulation disease dystonia NSD1 H3K36 SOTOS NUP98-NSD1 AML PRMT6 post-translational modification H3R2me2a SETD3 posttranslational modifications protein histidine methylation actin polymerization cytoskeleton enteroviruses oncogenesis PRMT5 cardiovascular disease neurodegenerative diseases diabetes inflammation G9a GLP EHMT2 EHMT1 post translational modification lysine methylation N-terminal methylation translation eEF1A METTL13 neuron synapse dendritic spine actin cytoskeleton GTPase PRMT1 arginine methylation H4R3 methylation transcriptional regulation cell signaling DNA damage repair PRMT2 SH3 SETMAR Metnase H3K36me2 Hsmar1 non-homologous end joining repair NHEJ transposase transposable elements histone SET7/9 SETD7 lysine-specific methyltransferase (PKMT) cell proliferation stress response post-translational protein modification |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566479603321 |
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Jeltsch Albert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Symmetry Breaking in Cells and Tissues
| Symmetry Breaking in Cells and Tissues |
| Autore | Goryachev Andrew |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (322 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
actin waves
curved proteins dynamic instability podosomes diffusion cell polarity Cdc42 stress cellular memory phase separation prions apoptotic extrusion oncogenic extrusion contractility actomyosin bottom-up synthetic biology motor proteins pattern formation self-organization cell motility signal transduction actin dynamics intracellular waves polarization direction sensing symmetry-breaking biphasic responses reaction-diffusion membrane and cortical tension cell fusion cortexillin cytokinesis Dictyostelium myosin symmetry breaking cytoplasmic flow phase-space analysis nonlinear waves actin polymerization bifurcation theory mass conservation spatial localization activator–inhibitor models developmental transitions cell polarization mathematical model fission yeast reaction–diffusion model small GTPases Cdc42 oscillations pseudopod Ras activation cytoskeleton chemotaxis neutrophils natural variation modelling activator-substrate mechanism mass-conserved models intracellular polarization partial differential equations sensitivity analysis GTPase activating protein (GAP) fission yeast Schizosaccharomyces pombe CRY2-CIBN optogenetics clustering positive feedback network evolution Saccharomyces cerevisiae polarity modularity neutrality |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557440703321 |
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Goryachev Andrew
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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