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Anticancer Drugs / Niamh M. O'Boyle, Mary J. Meegan
| Anticancer Drugs / Niamh M. O'Boyle, Mary J. Meegan |
| Autore | O'Boyle Niamh M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (214 p.) |
| Soggetto topico | Chemistry |
| Soggetto non controllato |
graphene oxide
indole androgens cyclooxygenase-2 cyclooxygenase-1 heteropolysaccharide drug conjugation drug delivery ellipticine chemical linker oesophageal cancer antiproliferative activity topoisomerase II ?-lactam DSD antibody topoisomerase inhibitors magnetic targeting cisplatin resistance steroidogenesis [18F]FDG PET/CT heterocyclic chemistry dehydroepiandrosterone antimitotic 3-vinylazetidin-2-ones glioblastoma and cancer therapy intestinal mucositis Combretastatin A-4 metabolism anti-cancer drugs maghemite COX-1 inhibitor anticancer CYP17A1 conjugate and hybrid drugs inflammation snticancer drugs P450c17 tumorigenesis cisplatin biomarker profiling cancer drug design tubulin cytochrome P450 5-fluorouracil prostate cancer abiraterone NCI screen radiation cancer immunotherapy microtubule targeted drugs cancer treatment resistance |
| ISBN |
9783039215874
3039215876 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367753903321 |
O'Boyle Niamh M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy : Future Perspectives
| Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy : Future Perspectives |
| Autore | Vermehren Charlotte |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (224 p.) |
| Soggetto topico |
Manufacturing industries
Medicine and Nursing |
| Soggetto non controllato |
2019 Beers criteria
5'nuclease assay 80 and over abacavir acute kidney injury adverse drug reaction adverse drug reactions aged allopurinol antidepressants antiepileptic drugs antipsychotics appropriateness bleeding children chronic clinical pharmacist clozapine CNV copy number variation cost-effectiveness CYP1A2 CYP2D6 CYP2D7P CYP2D8P cytochrome P450 cytochromes deprescribing deprescriptions determinants digital decision-support digital health DOACs drug hypersensitivity drug information service drug interaction checkers drug metabolization drug-drug interactions drug-gene interactions early biomarker electronic medical record electronic prescribing emergency department Ethiopia exosomes extracellular vesicles flucloxacillin general practice genotyping health outcomes health services research high resolution melting HLA hospital pharmacy service HRM loxapine medication adherence medication optimization medication reconciliation medication review medication-based risk score microvesicles multimorbidity nursing homes olanzapine older adults older patients outpatient personalized medicine persons with diabetes pharmacogene expression pharmacogenetics pharmacogenomics phenprocoumon plasma neutrophil gelatinase-associated lipocalin polypharmacy population-based potentially inappropriate medication use prevalence process evaluation quality of life shared medication record SLCO1B1 soluble urokinase plasminogen activator receptor thromboembolism utility youth |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy |
| Record Nr. | UNINA-9910595072903321 |
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Vermehren Charlotte
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0
| Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0 |
| Autore | Dansette Patrick M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (286 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
20-HETE
active site access channels Antibiotics arachidonic acid azole drugs Bacillus Bietti's crystalline dystrophy biosynthetic gene clusters cavities boundaries circulatory CYPs comparative analysis cryptococcus cryptococcus neoformans crystal structure Cyanobacteria CYP diversity analysis CYP128A1 CYP139A1 CYP2C8 CYP3A4 CYP4 genes CYP450 CYP51 Cytochrome b5 (CYB5) cytochrome P450 cytochrome P450 monooxygenase cytochrome P450 monooxygenases cytochrome P450 monooxygenenases cytochrome P450 reductase cytochromes P450 cytochromes P450 monooxygenases drug metabolism electron transfer electron-transfer (ET) enzyme substrate specificity exosomes extracellular vesicles extrahepatic tissues fatty acid fungal pathogens gene-cluster diversity percentage genetic polymorphisms genome data mining genome data-mining host metabolism human pathogens isoform lamellar ichthyosis mathematical formula mechanism-based inhibitor membrane protein menaquinone metabolism microsomal cytochrome P450 (CYP) minimal cost paths molecular dynamic simulations molecular dynamics simulation molecular functionality mutagenesis Mycobacterium Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv NADPH-cytochrome P450 reductase (CPR) non-ribosomal peptides P450 blooming P450 diversity percentage P450 profiling paclitaxel phylogenetic analysis plasma polyketides polymorphisms precision Cardio-Oncology precision medicine protein dynamics protein-membrane interactions protein-protein interaction reactive oxygen species RNA interference secondary metabolites SNPs Sogatella furcifera Streptomyces sulfoxaflor systems medicine terpenes transcriptome tremellomycetes trichosporon tuberculosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cytochromes P450 |
| Record Nr. | UNINA-9910557761103321 |
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Dansette Patrick M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Metabolism/Transport and Pharmacokinetics
| Drug Metabolism/Transport and Pharmacokinetics |
| Autore | Song Im-Sook |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (232 p.) |
| Soggetto topico |
Manufacturing industries
Medicine and Nursing |
| Soggetto non controllato |
acute renal failure
anti-obesity agent automatization BCRP biliary excretion breast cancer resistance protein Caco-2 carboxylesterase Carthamus tinctorius extract catalposide celecoxib cisplatin comparative pharmacokinetic study compatibility mechanism compound K creatinine clearance CYP3A4 cytochrome P450 cytochrome P450 enzymes diabetes dose-dependent pharmacokinetics drug absorption drug dosing drug interaction drug transporter drug-drug interaction DWP16001 efflux transporter EpiIntestinal first-pass fluorescence food-drug interactions gentamicin head-and-neck cancer healthy Korean subjects hepatic and intestinal first-pass effect hepatic CYP3A1(23) HPLC HSG4112 human hepatocytes in vitro human metabolism influx transporter inhibition mode inhibitor intestinal metabolism kidney distribution kinetic analysis large volume direct injection mertansine metabolism metformin modeling nonrenal clearance notoginseng total saponins oral availability organic cation transporter 2 P-gp pharmacokinetics physiologically based pharmacokinetic model population pharmacokinetic prazosin protopanaxadiol (PPD) quercetin rats real-time measurements renal clearance renal excretion repaglinide sodium-glucose cotransporter 2 (SGLT2) inhibitors stereoselectivity sulfasalazine sulfotransferase taxanes tiropramide tissue engineering tofacitinib transporter-enzyme interplay UDP-glucuronosyltransferase UDP-glucuronosyltransferases UHPLC-MS/MS verapamil |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607703321 |
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Song Im-Sook
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug-Drug Interactions
| Drug-Drug Interactions |
| Autore | Kim Dong Hyun |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (242 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
(‒)-sophoranone
1A2 2B6 2C19 2C8 2C9 2D6 3A4 ADME adverse drug reactions biflavonoid chronic kidney disease competitive inhibition computational prediction CYP CYP1A1 CYP1A2 CYP2C9 CYP2D6 CYP3A CYP3A4 cytochrome P450 cytochromes P450 DDI Dexamethasone drug interaction drug interactions drug metabolism drug transporter drug-drug interaction drug-drug interactions expression fexofenadine gepants high plasma protein binding in silico in vitro in vivo inhibitor ixazomib Ketoconazole lasmiditan Lexicomp low permeability Loxoprofen mechanism-based inhibition metabolic DDI metabolism migraine monoclonal antibodies non-competitive inhibition O-desmethyltramadol OATP1B1 OATP1B3 organic anion transporting polypeptide 1A2 (OATP1A2) P-glycoprotein (P-gp) P450 pharmacokinetics physiologically-based pharmacokinetics plasma concentration polypharmacy potent inhibition QSAR regulation Rumex acetosa selamariscina A signal detection algorithms spontaneous reporting systems subset analysis substrate systemic exposure tadalafil ticagrelor tissue-specific tramadol tyrosine kinase inhibitors ubiquitination uridine 5'-diphosphoglucuronosyl transferase |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557666403321 |
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Kim Dong Hyun
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Kidney Inflammation, Injury and Regeneration
| Kidney Inflammation, Injury and Regeneration |
| Autore | Koch Benjamin |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (496 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
2-kidney-1-clip
2k1c acute and chronic kidney disease acute kidney failure acute kidney injury AKI allograft rejection alport syndrome apoptosis arachidonic acid B-cell attracting chemokine biomarkers C-reactive protein cAMP Regulatory Element Binding Protein (CREB) chemerin chronic kidney disease chronic kidney disease (CKD) chronic kidney injury Class IIa Histone Deacetylases (HDAC) CmklR1 conditioned medium cPLA2 and COX-2 CREB Regulated Transcriptional Coactivators (CRTC) CXCL13 cyclooxygenase cytochrome P450 cytotoxicity dapagliflozin diabetes mellitus diabetic kidney disease diabetic kidney diseases diabetic nephropathy diagnostics differentiation DSS-colitis empagliflozin endotoxemia endotoxemia-induced oliguric kidney injury epithelial cells exosome exosomes extracellular vesicles Farnesiferol B fibrosis focal segmental glomerulosclerosis G-protein-coupled bile acid receptor (TGR5) genotype glomerular basement membrane glomerular damage glomerular filtration barrier (GFB) glomerular injury glomerulus GLP-1 receptor agonists haem hematuria hypertension IgA nephropathy IL-18 inflammation inflammatory bowel disease (IBD) inflammatory maker injury interleukin-6 ischemia-reperfusion ischemia/reperfusion injury kidney kidney inflammation kidney injury kidney proximal tubule kidney transplantation KIT assay KIT-IgA score lipoxygenase lncRNA long non-coding RNA long non-coding RNAs LPS-binding protein lysophosphatidic acid lysophosphatidic acid receptor mesenchymal stem cell mesenchymal stem cells mesenchymal stromal cells mesodermal stem cell microRNA microRNAs miRNA modified-MSCs modifier gene molecular mechanisms molecular signaling myofibroblast n/a natural products necrosis nephrin niches NLRP3 inflammasome non-coding RNAs noninvasive Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-?B) obese kidney fibrosis omega-3 fatty acid oxidative stress papilla pericyte pigment nephropathy podocin podocyte polymorphism polyploidization polyunsaturated fatty acids prediction proximal tubule regulated necrosis renal cell carcinoma renal fibrosis renal inflammation renal injury renal ischemia-reperfusion renal progenitors renal stem cells renal tubular cells renovascular hypertension rhabdomyolysis ROS Salt Inducible Kinase (SIK) scattered tubular cells SGLT2 inhibitors signal transduction signaling cascade slit diaphragm stem cell T cell-mediated rejection Taiwan therapeutic target therapeutics targets Thy1.1 nephritis transcription tubular injury type I collagen type IV collagen type V collagen xanthine oxidase |
| ISBN | 3-03928-539-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404091203321 |
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Koch Benjamin
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Mechanisms of Leaf Morphogenesis
| Molecular Mechanisms of Leaf Morphogenesis |
| Autore | Koyama Tomotsugu |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (164 p.) |
| Soggetto topico |
Biology, life sciences
Botany & plant sciences Research & information: general |
| Soggetto non controllato |
adaptation
adaptive significance of insect galls adaxial-abaxial polarity apical meristems AS2 body AS2/LOB domain ASYMMETRIC LEAVES2 BLR boundary BR BRAHMA carnivorous plants cheminformatics CIN-like TCP transcription factors Class I KNOX Class I KNOX genes compound leaves crop yield Crosstalk CUC CYP78A5 cytochrome P450 determinacy Dryopteridaceae Elaphoglossum embryogenesis ETTIN/AUXIN RESPONSE FACTOR3 (ETT/ARF3) ferns fronds gall formation mechanism gall-inducing insects gene body methylation high temperature insect effectors KLU KNAT6 LAS Leaf angle leaf development leaf diversity leaf evolution and development light liverwort megaphyll metabolomics microRNA319 Nepenthes nucleolus Phytohormones pinna development regulation ribosomal DNA (rDNA) Riccia fluitans sexual induction shoot development shoot meristem stem cell STM TEAR1 E3 ligases terrestrialization TIE1 transcriptional repressors tissue specificity transcription factor transformation UPLC-qToF-MS |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557615603321 |
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Koyama Tomotsugu
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mycotoxins in Feed and Food Chain : Present Status and Future Concerns
| Mycotoxins in Feed and Food Chain : Present Status and Future Concerns |
| Autore | Rossi Filippo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (224 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
aflatoxin
Aflatoxins Alternaria mycotoxins AMF1 Atlantic salmon azoxystrobin binding bioactive compounds biocontrol black soldier fly botryodiplodin BSFL carcinogenic risk index cereals charcoal rot disease Claviceps co-occurrence combinatory effects combined toxicity cytochrome P450 deoxynivalenol deoxynivalenol (DON) DON enniatin B (EnnB) enzyme induction ergochromes ergot alkaloids estimated daily intake food contamination food discipline food safety fumonisin Fumonisins fungal disease fungi fungicide Fusarium species Fusarium spp growing season health issues Hermetia illucens HT-2 toxin human exposure hydroponic culture infant formulae LC/MS liquid chromatography high-resolution mass spectrometry Macrophomina phaseolina maize products metabolic conversion Monterrey (Mexico) mycotoxin mycotoxin migration mycotoxins n/a phaseolinone phytoestrogens plant-based feed rice root infection mechanism root toxicity S9 fraction secalonic acid secondary metabolites size sorting soybean STC sterigmatocystin sweet pepper T-2 toxin tetrahydroxanthones toxigenic profile unprocessed cereals zebrafish |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Mycotoxins in Feed and Food Chain |
| Record Nr. | UNINA-9910557299203321 |
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Rossi Filippo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sulfur-Containing Marine Bioactives
| Sulfur-Containing Marine Bioactives |
| Autore | Palumbo Anna |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (140 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adjuvant
age-related macular degeneration aggregates algae angiogenesis anti-settlement antioxidant antioxidant capacity autotrophic culture biofouling brown seaweed extracts carbohydrate sulfotransferase carrageenan chemical synthesis colloid cytochrome P450 cytotoxic effects on tumor cells diatoms eco-friendly exopolysaccharides FGF2 fucan fucoidan galactose-6 sulfurylase gallic acid heterotrophic culture immunomodulatory activity invasion Laminaria hyperborea light marine coatings MMP-2 MMP-9 molecular weight natural products nitric oxide ovothiol oxidative stress proliferation propylene glycol alginate sodium sulfate rare actinobacteria red alga reproduction stages retinal pigment epithelium screening structure elucidation sulfated sulfavants Tetraselmis suecica thiopeptide antibiotic VEGF WD 40 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557113603321 |
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Palumbo Anna
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Impact of Caffeine and Coffee on Human Health
| The Impact of Caffeine and Coffee on Human Health |
| Autore | Cornelis Marilyn |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (322 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
24-h dietary recall
accidental death adenosine adenosine receptor ADORA2A adult age aging alcohol consumption anxiety assisted reproduction techniques behavior bias biomarkers caffeine Caffeine caffeine intake caffeine intoxication caffeine metabolism cardiovascular disease causality causation chlorogenic acids chocolate clinical pregnancy coffee coffee consumption cognition cognitions cognitive cohort study consumption coronary artery disease country CYP1A2 cytochrome P450 depression did not respond dipyridamole energy drinks epidemiological methods epidemiology ergogenic ergogenic aid European Prospective Investigation into Cancer and Nutrition exercise expectancy gene expression gene-diet interaction genetic epidemiology guidelines health hearing HIV-HCV co-infection implantation individual responses intoxication lipidomics lipids live birth liver fibrosis longevity lysophosphatidylcholine mate Mendelian Randomization mood mRNA myocardial perfusion n/a NADH dehydrogenase pharmacogenomics pharmacological ergogenic aid phenolic placebo polymorphism population pregnancy protection public policy regadenoson responders risk factors safety serum chloride levels sex soda sport Suicide supplement systematic review tea the Norwegian Women and Cancer Cohort (NOWAC) time trial performance tinnitus transcriptomics trial whole-blood wine |
| ISBN | 3-03921-835-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367738403321 |
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Cornelis Marilyn
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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