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Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (594 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
thymidylate synthase
cytotoxicity 1,2,3-triazole 1,3,4-oxadiazole 5-fluoruracil pemetrexed docking 3,4'-bis-guanidino 3-amino-4'-guanidino diphenyl ether phenyl pyridyl ether intramolecular hydrogen bond cancer cell viability HL-60 BRAF apoptosis thieno[2,3-d][1,2,3]triazine acetamide H1299 HER2 EGFR Bcl-2 inhibitors Indole-based analogues benzimidazole MTT cytotoxic assay cell cycle analysis DNA fragmentation ELISA solid/lipid nanoparticles phenstatin letrozole tubulin polymerisation inhibitor aromatase inhibitor breast cancer hybrid molecule dual-targeting molecule designed multiple ligand NaMSA cyclophosphamide histopathology testis urinary bladder anticancer agents enantioselective synthesis gastric adenocarcinoma tryptophanol concentration-guided dosing model informed dosing physiologically based pharmacokinetics sorafenib tyrosil-DNA-phosphodiesterase 1 adamantane resin acid TDP1 cytotoxic agents apoptosis induction HT-29 cells MDA-MB-231 cells mechanism prediction STAT inhibitors miR-21 hydrazide derivatives nitrogen scaffolds mitoxantrone cardiotoxicity inflammation oxidative stress age cumulative dose Trk NTRK tissue-agnostic larotrectinib entrectinib Trk fusion protein kinase inhibitors USFDA cancer patent review generic product doxazosin MD simulations combretastatin A-4 cytotoxic activity hybrid compounds indazole mucin MUC1 MUC16 immunotherapy cancer vaccine CAR (chimeric antigen receptor) ADC (antibody-drug conjugate) thiourea interleukin-6 trypan blue assay chalcones exportin-1 covalent binding CovDock anticancer activity xanthone in vitro in vivo isolation synthesis heterocyclic compound benzenesulfonamides imidazoles alkylated colony formation tumor spheroids HDAC inhibitors chalcone dual inhibitors carvedilol kidney toxicity 7-deaza-4'-thioadenosine derivatives multi-kinase inhibitor anticancer nucleoside Imiquimod drug efflux multidrug resistance Toll-Like Receptor |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
Meegan Mary J
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Molecules with Healthy Features to Food and Non-food Applications
| Bioactive Molecules with Healthy Features to Food and Non-food Applications |
| Autore | Torres María Dolores |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (150 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
anti-hypertension
bioactivity Gaba Gaba-rich product health benefit Nibea japonica marine collagen peptides proliferation wound healing processing by-products Meretrix meretrix oligopeptides cyclophosphamide immunomodulatory immune-deficient mice Cytisus scoparius Pleurotus ostreatus Brassica rapa Quercus robur sun creams thermal spring waters fermentation fermented foods whole grains health benefits phenolic compounds antioxidant activity bee products bioactive molecules cosmetics emulsion functional matrices honey hydration organoleptic properties transepidermal water loss bioactive peptides in vitro gastrointestinal digestion fish byproduct hydrolysate cholecystokinin glucagon-like peptide 1 DPP-IV inhibitory peptides Taxus baccata L. red arils polymethylene-interrupted fatty acids α-linolenic acid nutritional value amino acids elements |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557495803321 |
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Torres María Dolores
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Basis and Gene Therapies of Cystic Fibrosis
| Molecular Basis and Gene Therapies of Cystic Fibrosis |
| Autore | Engelhardt John |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (210 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
cystic fibrosis
Staphylococcus aureus superantigen enterotoxin gene cluster MRSA exosomes microvesicles lung primary cells newborn screening trypsinogen CFTR gene next generation sequencing health policy rAAV2/HBoV1 baculovirus insect cells lung microbiome metagenomics gut–lung axis Cystic fibrosis CFTR transcriptomics proteostasis small molecules drug development common and new pathogenic variants ethnic Russian population gene therapy cyclophosphamide transient immunosuppression incidence survival genotype-phenotype correlations health policies CFTR modulators human nasal epithelial cells organoids biomarker functional assay pre-clinical in vitro models CFTR-related disorders molecular diagnosis CFTR variants Next Generation Sequencing (NGS) disease liability interpretation penetrance genotype-guided therapy miRNA airway basal cell lentivirus |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557392203321 |
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Engelhardt John
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oxidative Stress and Inflammation : From Mechanisms to Therapeutic Approaches
| Oxidative Stress and Inflammation : From Mechanisms to Therapeutic Approaches |
| Autore | Gambini Juan |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (234 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
diospyrin
lipopolysaccharide anti-inflammation macrophages nitric oxide cytokine calcium CHOP Fas p38 MAPK Astragalus mongholicus Bunge danazol telomere telomerase aging diabetic kidney disease oxidative stress redox imbalance hyperimmunized milk exercise inflammation intestinal permeability acute respiratory distress syndrome antiplatelet aspirin therapy gender membrane erythrocyte hydroperoxides biomarker DPPP DPH TMA cardiovascular disease data analysis precision-recall Mediterranean diet Oriental diet nutrition polyphenols microbiota health n-3 PUFAs endogenous antioxidants anti-inflammatory response cardiovascular diseases dry eye syndrome corneal damage tear lipidome 5-lipoxigenase leukotriene B4 prostaglandins dimethyl sulfoxide zileuton air pollution soot particulate matter lung inflammation functional groups microglia porcine liver decomposition product lysophospholipids mild cognitive impairment dementia neuroinflammation cytokines oxygen reactive species caloric restriction oxidative balance adiponectin plasma white adipose tissue experimental model anti-inflammatory diets inflammatory response chronic inflammation low grade chronic inflammation inflammatory models cyclophosphamide doxorubicin docetaxel paclitaxel |
| ISBN | 3-0365-6024-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Oxidative Stress and Inflammation |
| Record Nr. | UNINA-9910637783403321 |
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Gambini Juan
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmaceutical Residues in the Environment
| Pharmaceutical Residues in the Environment |
| Autore | Kumirska Jolanta |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (292 p.) |
| Soggetto topico |
Research & information: general
Environmental economics |
| Soggetto non controllato |
ifosfamide
cyclophosphamide 5-fluorouracil cytostatic drug BDD anode electrochemical oxidation intermediates lincomycin monensin roxarsone migration residual toxicity pharmaceuticals endocrine disrupting compounds hydroponic cultivation determining target pollutants in plant materials municipal wastewater treatment plants ionic liquids green chemistry environmental and biological samples sample preparation determination of pharmaceuticals chromatographic methods electromigration techniques sulfamethoxazole antibiotic resistance genes sul genes bacterial community constructed wetlands environmental contaminants pharmaceuticals occurrence aquatic compartments soil poultry farms ultra-high performance liquid chromatography antibiotics, antibiotic resistance antibiotics wastewater sewage sludge risk assessment removal efficiency LC-MS/MS analysis Spirotox fluoxetine sertraline paroxetine mianserin pharmaceuticals in the environment wastewaters pharmaceutical residues conventional wastewater treatments solid phase extraction pharmaceuticals toxicity environmental risk assessment antibiotic resistance genes (ARGs) antibiotic-resistant bacteria (ARB) wastewater treatment plants (WWTPs) activated sludge (AS) constructed wetlands (CWs) environmental pollution spread of resistance tetracyclines sulfonamides fate in the environment fate in WWTPs ecotoxicity antibiotic resistance development of methods |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557113103321 |
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Kumirska Jolanta
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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