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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (528 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
melanoma
invasion WNT5A MARCKS phosphorylation MANS peptide nanoparticles cell therapy tumor microenvironment sex/gender sex-hormones immunity microRNAs immunotherapy BRAF-mutant melanoma BRAF inhibitor mechanism of action targeted therapy tumour microenvironment plasmacytoid dendritic cells lactate dehydrogenase TLR interferon CXCL10 TPC2 HIPPO SOCE metastasis essential oils angiogenesis apoptosis uveal melanoma (UM) metastatic uveal melanoma (mUM) prognostication adjuvant therapy metastatic therapy metastatic dormancy liver-directed-therapies targeted-therapy combined therapy protein tyrosine phosphatase PTPs inhibitors melanoma immune infiltrate BRAF inhibitors microenvironment resistance therapy therapeutic resistance exosomes extracellular vesicles diagnosis prognosis ctDNA liquid biopsy prediction patient stratification BRAF arthralgia rheumatoid arthritis carbonic anhydrase hedgehog cyclopamine small molecules acetazolamide motility metalloproteinases FAK cancer mucosal melanoma nivolumab pembrolizumab ipilimumab radiotherapy cholinergic system acetylcholine muscarinic receptors nicotinic receptors melanoma metastasis ShcD adaptor protein amoeboid motility Rac1 DOCK4 melanoma PDX target therapy cancer stem cells slow cycling phenotype drug resistance OXPHOS lipid metabolism cancer associated fibroblast melanomagenesis biomarkers checkpoint inhibitor PD-1 melanoma markers cytokines machine learning Support Vector Machine principal component analysis BCL2L10 STAT3 cytotoxicity survival ABT-737 Bcl-2 family ML258 HuR MITF metastases siRNA |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Plant Alkaloid Research
| Advances in Plant Alkaloid Research |
| Autore | D'Auria John C |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (278 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
canthin-6-one
Picrolemma huberi Simaroubaceae antiplasmodial activity Sarcococca hookeriana sarchookloides A–C steroidal alkaloid cytotoxicity Rhodophiala alkaloids molecular docking AChE BuChE GC-MS Mahonia imbricata Berberidaceae isoquinoline alkaloid mahimbrine A hedgehog signaling Veratrum californicum cyclopamine HPLC-MS Shh-Light II cells halogencyclopropane dichlorocarbene epoxidation vindoline catharanthine dimer alkaloids vindoline trimer Ruta graveolens photosystem II Chl a fluorescence Hill reaction inhibitors acridone alkaloids benzylisoquinoline alkaloids cytochrome P450 monooxygenase medicinal properties methyltransferase Nelumbo nucifera norcoclaurine synthase sacred lotus stereochemistry Aristotelia chilensis Molina Stuntz vascular activity endothelium-independent indole alkaloid 8-oxo-9-dihydromakomakine voltage-dependent calcium channels Catharanthus roseus cambial meristematic cells Aspergillus flavus terpenoid indole alkaloids biosynthesis Buxaceae Borago officinalis Crassocephalum Copper-dependent diamine oxidase Gynura bicolor Homospermidine synthase Lolium perenne Necic acids Necine bases Pyrrolizidine alkaloid biosynthesis Senecionine tropane alkaloids scopolamine cocaine calystegine chemistry pharmacology biotechnological production Erythroxylaceae Erythroxylum coca next generation sequencing traditional medicine bioprospecting tropane late-stage functionalization sulfinate DiversinateTM natural product medicinal chemistry papaverine scaffold library biodiscovery Swinglea glutinosa dereplication acridones phenylacrylamides |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557109903321 |
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D'Auria John C
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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