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Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing
| Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing |
| Autore | Pörtner Ralf |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (226 p.) |
| Soggetto topico |
Technology: general issues
History of engineering & technology |
| Soggetto non controllato |
clonal cell population
phenotypic diversity inoculum train uncertainty-based cell culture model biopharmaceutical manufacturing Escherichia coli hybrid modeling machine learning model-assisted DoE quality by design upstream bioprocessing surface plasmon resonance (SPR) bioprocess monitoring biosensor quality by design (QbD) process analytical technology (PAT) biotherapeutics production vaccines production CHO DP-12 computational fluid dynamics bioreactor characterization hydrodynamic gradients process development critical shear stress Kolmogorov length scale operational space sensors cell culture spectroscopy PAT smart biomanufacturing soft-sensor Adeno-associated virus transfection PEI continuous gene therapy microcarriers bioreactor transient expression spheroid strength β-cells diabetes shear stress-guided production hydrodynamic stress Gaussian processes Bayes optimization Pareto optimization multi-objective seed train Chinese hamster ovary cells cryopreservation monoclonal antibodies N−1 perfusion process intensification upstream processing |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595072803321 |
Pörtner Ralf
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Modelling of River Flows, Sediment and Contaminants Transport
| Modelling of River Flows, Sediment and Contaminants Transport |
| Autore | Krishnappan Bommanna |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (152 p.) |
| Soggetto topico |
Technology: general issues
Environmental science, engineering & technology |
| Soggetto non controllato |
Congo River Basin
Cuvette Centrale erosion sediment transport sediment balance SWAT dam area of reservoirs fine-grained sediment fluid mud gravity-driven flow reservoir sedimentation cohesive sediment water supply turbidity gravel bed river ingress watershed management source water protection climate change adaptation landscape disturbance aquatic life bank erosion bed shear ice jam sediment pulse suspended-sediment concentration water quality cohesive sediment transport modelling flocculation critical shear stress deposition river systems entrapment |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566480703321 |
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Krishnappan Bommanna
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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