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Drug Metabolism/Transport and Pharmacokinetics
| Drug Metabolism/Transport and Pharmacokinetics |
| Autore | Song Im-Sook |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (232 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
tofacitinib
dose-dependent pharmacokinetics hepatic and intestinal first-pass effect rats catalposide in vitro human metabolism UDP-glucuronosyltransferase sulfotransferase carboxylesterase celecoxib drug–drug interaction fluorescence HPLC metabolism repaglinide HSG4112 anti-obesity agent stereoselectivity pharmacokinetics compound K protopanaxadiol (PPD) biliary excretion intestinal metabolism Carthamus tinctorius extract notoginseng total saponins comparative pharmacokinetic study large volume direct injection compatibility mechanism mertansine human hepatocytes cytochrome P450 UDP-glucuronosyltransferases sodium-glucose cotransporter 2 (SGLT2) inhibitors DWP16001 kidney distribution inhibition mode diabetes transporter-enzyme interplay influx transporter efflux transporter physiologically based pharmacokinetic model cytochrome P450 enzymes tiropramide healthy Korean subjects modeling population pharmacokinetic quercetin breast cancer resistance protein inhibitor prazosin sulfasalazine kinetic analysis food–drug interactions Caco-2 EpiIntestinal first-pass P-gp BCRP drug transporter CYP3A4 oral availability automatization drug absorption drug dosing head-and-neck cancer real-time measurements taxanes tissue engineering UHPLC-MS/MS metformin verapamil drug interaction organic cation transporter 2 renal excretion acute renal failure gentamicin cisplatin hepatic CYP3A1(23) creatinine clearance renal clearance nonrenal clearance |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607703321 |
Song Im-Sook
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Toxic Metals, Chronic Diseases and Related Cancers
| Toxic Metals, Chronic Diseases and Related Cancers |
| Autore | Satarug Soisungwan |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (318 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
Trace elements
hair children hazardous waste incinerator Constantí (Catalonia, Spain) blood lead level boatyard childhood lead poisoning fishing community lead weights β2-microglobulin cadmium creatinine clearance glomerular filtration N-acetyl-β-d-glucosaminidase nephron mass nephrotoxicity trace elements autopsy tissues temporal trends creatinine excretion glomerular filtration rate lead kidney endocytosis metallothionein flow cytometry proximal tubule epithelial cells OGTT minimal model glucose response mechanism genotoxicity aluminum chloride rats food farmer PTWI (provisional tolerable monthly intake) TWI (tolerable weekly intake) Monte Carlo simulation mercury obesogen lipid profiles hyperlipidemia elevated liver enzymes hexavalent chromium [Cr(VI)] mitochondrial fragmentation dynamin-related protein 1 (Drp1) mitochondrial respiratory chain complex I (MRCC I) reactive oxygen species (ROS) blood lead cellular immunity phagocytosis humoral munity immunosuppression insulin diabetes hyperglycemia hyperinsulinemia lipogenic β-cell toxicity stroke cerebrovascular accident heavy metal rare earth element case-control study mortality lifetime cadmium intake renal diseases urinary cadmium a follow-up study diet kidney function chronic kidney disease threshold limit tolerable intake level heavy metals birth weight preterm birth diet pattern Mediterranean diet pregnancy toxic metals reproduction testicular and ovarian structure |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580214603321 |
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Satarug Soisungwan
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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