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Drug Metabolism/Transport and Pharmacokinetics
| Drug Metabolism/Transport and Pharmacokinetics |
| Autore | Song Im-Sook |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (232 p.) |
| Soggetto topico |
Manufacturing industries
Medicine and Nursing |
| Soggetto non controllato |
acute renal failure
anti-obesity agent automatization BCRP biliary excretion breast cancer resistance protein Caco-2 carboxylesterase Carthamus tinctorius extract catalposide celecoxib cisplatin comparative pharmacokinetic study compatibility mechanism compound K creatinine clearance CYP3A4 cytochrome P450 cytochrome P450 enzymes diabetes dose-dependent pharmacokinetics drug absorption drug dosing drug interaction drug transporter drug-drug interaction DWP16001 efflux transporter EpiIntestinal first-pass fluorescence food-drug interactions gentamicin head-and-neck cancer healthy Korean subjects hepatic and intestinal first-pass effect hepatic CYP3A1(23) HPLC HSG4112 human hepatocytes in vitro human metabolism influx transporter inhibition mode inhibitor intestinal metabolism kidney distribution kinetic analysis large volume direct injection mertansine metabolism metformin modeling nonrenal clearance notoginseng total saponins oral availability organic cation transporter 2 P-gp pharmacokinetics physiologically based pharmacokinetic model population pharmacokinetic prazosin protopanaxadiol (PPD) quercetin rats real-time measurements renal clearance renal excretion repaglinide sodium-glucose cotransporter 2 (SGLT2) inhibitors stereoselectivity sulfasalazine sulfotransferase taxanes tiropramide tissue engineering tofacitinib transporter-enzyme interplay UDP-glucuronosyltransferase UDP-glucuronosyltransferases UHPLC-MS/MS verapamil |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607703321 |
Song Im-Sook
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Toxic Metals, Chronic Diseases and Related Cancers
| Toxic Metals, Chronic Diseases and Related Cancers |
| Autore | Satarug Soisungwan |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (318 p.) |
| Soggetto topico | Public health and preventive medicine |
| Soggetto non controllato |
a follow-up study
aluminum chloride autopsy tissues birth weight blood lead blood lead level boatyard cadmium case-control study cellular immunity cerebrovascular accident childhood children chronic kidney disease Constantí (Catalonia, Spain) creatinine clearance creatinine excretion diabetes diet diet pattern dynamin-related protein 1 (Drp1) elevated liver enzymes endocytosis farmer fishing community flow cytometry food genotoxicity glomerular filtration glomerular filtration rate glucose response mechanism hair hazardous waste incinerator heavy metal heavy metals hexavalent chromium [Cr(VI)] humoral munity hyperglycemia hyperinsulinemia hyperlipidemia immunosuppression insulin kidney kidney function lead lead poisoning lead weights lifetime cadmium intake lipid profiles lipogenic Mediterranean diet mercury metallothionein minimal model mitochondrial fragmentation mitochondrial respiratory chain complex I (MRCC I) Monte Carlo simulation mortality N-acetyl-β-d-glucosaminidase n/a nephron mass nephrotoxicity obesogen OGTT phagocytosis pregnancy preterm birth proximal tubule epithelial cells PTWI (provisional tolerable monthly intake) rare earth element rats reactive oxygen species (ROS) renal diseases reproduction stroke temporal trends testicular and ovarian structure threshold limit tolerable intake level toxic metals trace elements Trace elements TWI (tolerable weekly intake) urinary cadmium β-cell toxicity β2-microglobulin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580214603321 |
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Satarug Soisungwan
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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