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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (606 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
1,2,3-triazole
2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide 3,6-dibromocarbazole 4-(pyridin-4-yloxy)benzamide 5-bromoindole 5-fluorouracil ABCB1 (P-glycoprotein) actin ADME allene amides/esters androgen receptor anti-cancer activity anti-neuroinflammation anti-ovarian cancer anti-tumor anticancer anticancer activity anticancer agent anticancer agents anticancer compounds antimitotic agents antioxidant activity antiproliferative activity antiproliferative agent antitumor antitumor activity apalutamide apoptosis aromatase benzimidazole benzofuran-pyrazole benzofurans beta-lapachone bivalency breast cancer c-Met carbazole cell cycle chemical synthesis chemoresistance chrysin analogues colchiceine colchicine amide colchicine analogs colchicine sulfonamide colon cancer computational docking coumarin crystal structure cyanopyridone cytotoxic activity cytotoxic properties cytotoxicity darolutamide DFT study dihydroartemisinin dihydropyranoindole docking docking studies drug discovery drug resistance E-stereoselective enzalutamide enzyme inhibition estrone derivatives flavonoid flavonoids gemcitabine HDAC inhibitors HeLa HepG2 hydrates hydrazine IGF-1R IL-12 immune modulation indoleamine 2,3-dioxygenase inflammation inhibitor K562 kinase inhibitor MCF-7 MDM2-p53 interaction migration mimetics molecular simulation MOLT-4 multidrug resistance (MDR) reversal N-substituted pyrazoline nanoparticles natural product neuroblastoma NIH3T3 o-nitro-benzyl organosilicon compounds ortho-quinones ovarian cancer overcoming drug resistance P-glycoprotein P-MAPA PARP inhibitor PARP-1 inhibition phenylpyrazolopyrimidine photoactivatable protecting groups PI3Ks PI3Kα inhibitor PI3Kδ inhibitors polyvalency prodrug prostate cancer PROTACs protein degradation protein kinase protein-protein interactions Pyrazole pyrazolopyridine pyridotriazine quinazolin-4(3H)-one quinazolin-4(3H)-thione regioselective salinomycin Schiff base SILA-409 (Alis-409) SILA-421 (Alis-421) Src substituted pyridine synergy synthesis Talazoparib tanshione IIA taxoids thiazolidinone Thienopyrimidine thienopyrimidinone thiocolchicine thiopene thioxotriazopyridine TLR signaling topoisomerase II inhibitor triazolothiadiazine triple-negative breast cancer tryptophan metabolism tubulin inhibitors tumor specificity urea virtual screening xanthones yeast-based assays zampanolide βIII-tubulin |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species
| Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species |
| Autore | Nicoletti Rosario |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (134 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
antibacterial
antibacterial activity antifungal activity Aspergillaceae Aspergillus Aspergillus candidus Aspergillus clavatus aspetritone bioactive products bis-indolyl benzenoids BK (Maxi-K) channel breast cancer breviane spiroditerpenoid candidusin chromone coumarin cytotoxic cytotoxicities cytotoxicity diastereomers diterpenoid drug discovery ECD calculations EGFR endophytic fungi gefitinib HER2 hydroxypyrrolidine IDH1 inhibitory activity indole-diterpenoids lapatinib mangrove endophytic fungus mangroves marine-derived fungi n/a NMR data calculations Penicillium raistrickii Penicillium sp. TJ403-1 penitrem A polyketides secondary metabolites sesquiterpenoid sponge-associated fungus sterone Talaromyces Talaromyces purpurogenus thermo-change strategy TNF-? |
| ISBN | 3-03897-981-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346857703321 |
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Nicoletti Rosario
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biocatalytic Synthesis of Bioactive Compounds
| Biocatalytic Synthesis of Bioactive Compounds |
| Autore | Aleu Josefina |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (142 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
8-hydroxydaidzein
active agent synthesis adaptation alkene cleavage amylosucrase anti-inflammation aryl alkenes basidiomycota biocatalysis biocatalyst bioprocess biotransformation bromination carotene degradation chlorination coumarin Deinococcus geothermalis dye-decolorizing peroxidase (DyP) filamentous fungi glycerol Glycine max (L.) Merr glycosyltransferase halogenase haloperoxidase HPLC/MS in situ product removal isoflavone aglycone-rich extract isoflavone α-glucoside Komagataella pfaffii limonene lipase manganese mevalonate pathway monoterpenes oxidation oxidative cleavage pharmaceuticals Pleurotus sapidus psychrotrophs reaction engineering selective hydroxylation soluble stable terpenes two-liquid phase fermentation unsaturated fatty acid UV/NTG mutagenesis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557380503321 |
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Aleu Josefina
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Coumarin and Its Derivatives
| Coumarin and Its Derivatives |
| Autore | Matos Maria João |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (406 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
3-aroylcoumarines
4-hydroxy-7-methoxycoumarin 4-hydroxycoumarin 6'-(4-biphenyl)-β-iso-cinchonine acenocoumarol adenosine receptors analytical methods anti-HIV antibacterial activity anticancer activity anticoagulation antiplatelet activity apoptosis autophagy benzopyrones benzyl 2,3-butadienoate binding affinity bioactivity biological applications biosynthesis biotransformation calanolide A calanolides Calophyllaceae Calophyllum chalcocoumarin chalcone chalepensin chalepin charge transfer cholinesterase inhibition cholinesterases Chromobacterium violaceum complementary therapies constitutive androstane receptor coumarin coumarin dyes coumarin3-carboxamides coumarins COX Crohn's disease curcumin curcumin-coumarin hybrids dihydrocoumarin-fused dihydropyranones direct laser write docking docking simulation drug discovery dye-sensitized solar cells electrophilic compounds Escherichia coli esculetin esculin ethynylaryl ferulenol five-membered aromatic heterocycles fluorescent probes free radical polymerization furan glutathione glycyrol Glycyrrhiza uralensis human monoamine oxidases hydroxyl-modified coumarin imidazole immunoproteasome impedance aggregometry in silico studies in silico tools inflammation inflammatory bowel disease intestinal inflammation isocoumarin kinetics LED liquiritigenin macrophage MAO-B MAPK mechanical valve model plant molecular dynamics monoamine oxidase inhibition n/a natural genetic variation natural products neurodegenerative diseases neuroprotection NF-κB non-nucleoside reverse transcriptase inhibitors (NNRTIs) non-peptidic osthole oxazole oxidative stress photocomposites photophysical plant-derived molecules polyphenols pseudocalanolides psoralen core pyranocoumarins pyrazole pyrrole QS inhibitors quorum sensing reverse transcriptase Ruta chalepensis Rutaceae scavenging activity scoparone selenophen simple coumarins sorafenib structural annotation thermal and structural characterization thiadiazole thiazole thieno [3,2-b] thiophene thiophene time in therapeutic range triazole ulcerative colitis umbelliferone warfarin warhead scan Yin Chen Hao |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557577003321 |
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Matos Maria João
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Modern Seed Technology
| Modern Seed Technology |
| Autore | Taylor Alan G |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (183 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general Technology, Engineering, Agriculture, Industrial processes |
| Soggetto non controllato |
abiotic stress
baby leaf hemp blindness Brassica oleracea chemometrics chlorophyll content containerized transplants corn coumarin crop establishment cultivar selection field emergence film coat fluorescent tracer fruit morphology heat and drought stresses heatmaps humic acids image analysis in vivo imaging system (IVIS) low phytic acid multispectral multispectral imaging n/a near-infrared oil-bodies migration organic agriculture pellet pericarp physiological maturity piperonyl amides potassium nitrate relative growth rate (RGR) seed acquisition of desiccation tolerance seed coat seed coating seed dressing seed enhancement seed health seed quality seed respiration seed testing seed treatment seed vigor seed-size distribution Solanum lycopersicum L. sowing density soybean specific root length (SRL) spectroscopy spinach systemic uptake testa tissue lipophilicity Vigna unguiculata (L.) Walp Zn localization Zn priming |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557366203321 |
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Taylor Alan G
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Modern Strategies for Heterocycle Synthesis
| Modern Strategies for Heterocycle Synthesis |
| Autore | Favi Gianfranco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (372 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
1-oxa-triene
1,2,3-triazol 1,3-oxazines 1H-imidazole-2(3H)-thione 2H-imidazo[2,1-b][1,3,4]thiadiazine 2H-pyran 3-trifluoroacetyl coumarins 3,2':6',3"-terpyridine 4-bromo quinolines 5-acylamino-1,3-thiazoles acylhydrazone group alkynes alkynoic acids amine nucleophiles antifungal activities antitumor aromatic substitution arylation asymmetric dimeric β-carboline aza-Wittig azides cascade cyclization cascade reaction CF3CO-acetylenes cinnolines click reaction condensation copper-catalyzed azide-alkyne cycloaddition coumarin CuAAC cyclic ethers cycloalkynes cyclohexanol derivative cycloisomerization cytotoxic cytotoxicity dienone dihydrocoumarins enol ethers fluorescence fluorinated heterocycles fluoroalcohol fused N-heterocycles gold catalysis Hantzsch reaction heterocycles heterocyclic inter-molecular approach intra-molecular approach ketone Knoevenagel multicomponent reaction multicomponent reactions n/a natural products nucleobase organic dyes organocatalysis oxa-electrocyclization phenols photocatalysis photoredox photoredox cyclization propargyl Claisen propargylic alcohols purine pyrazolo[3,4-b]pyridine pyridine pyrrolidones Richter cyclization saturated oxygen heterocycles silica sulfuric acid solid-phase synthesis Staudinger reaction structure-activity relationship Suzuki coupling synthesis synthesis of benzofurans terpyridines TMSBr total synthesis traceless synthesis triazoles triazolylmethyl phosphate triazolylmethyl phosphinate valence isomerism visible-light-induced catalysis α-chloroglycinates α-halohydrazones γ-lactam |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557409903321 |
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Favi Gianfranco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oxidative Stress Modulators and Functional Foods
| Oxidative Stress Modulators and Functional Foods |
| Autore | Taira Junsei |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (244 p.) |
| Soggetto topico |
Manufacturing industries
Medicine and Nursing |
| Soggetto non controllato |
(-)-loliolide
altitude variations antimicrobial activity antimutagenicity antioxidant antioxidant activity antioxidant compounds antioxidant effect antioxidative mechanisms apoptosis Benzo[a]pyrene bilberry BPDE-DNA adduct cardiac dysfunction coumarin cudratrixanthone O dendrimer diabetes mellitus DPPH electronic effect epigallocatechin-gallate ESR fibrosis fine dust folic acid fucoidan gradient ethanol precipitation HaCaT HaCaT keratinocyte heme oxygenase-1 hemeoxygenase-1 high sugar-fat diet HO-1 hydrogen atom transfer (HAT) in vivo model inflammation jujube pomace kidney damage LC/MS lingonberry liposomes lycopene mitochondria myricetin n/a neural tube defects neurodegeneration nitric oxide NOR3 Nrf2 nuclear transcription factor erythroid-2-like factor 2 nutricosmetic nutrient obesity oxidative stress Peucedanum japonicum Thunb phase detoxifying enzyme physiological conditions polyphenols polysaccharide pteryxin QM-ORSA Quamoclit angulata RAW264.7 cells reaction rate constants reactive oxygen species Sargassum horneri sequential proton loss electron transfer (SPLET) single electron transfer-proton transfer (SET-PT) structural analysis tomato-oleoresin type 2 diabetes ultraviolet B zebrafish embryo β-adrenergic system |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557361503321 |
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Taira Junsei
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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PPARs as Key Mediators of Metabolic and Inflammatory Regulation
| PPARs as Key Mediators of Metabolic and Inflammatory Regulation |
| Autore | Vázquez-Carrera Manuel |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (456 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research and information: general |
| Soggetto non controllato |
adipose tissue
AMPK amygdala atopic dermatitis bezafibrate brain browning cancer common carotid artery occlusion coregulator corticotropin releasing hormone coumarin crystal structure cytomegalovirus dairy animals depression diabetes DNA methylation docking doping control dual/pan agonist electroretinography ELISA energy homeostasis exercise fatty acid oxidation fatty acids fenofibrate fenofibric acid fibroblast growth factor 21 fluorescent ligand GDF15 gene transcription glucose GSK3787 GW0742 hepatic damage hepatic sex-biased gene expression histone modification HIV immunity immunohistochemistry infection inflammation insulin resistance kidney fibrosis ligand lipid droplets lipid metabolism lipidomics lipopolysaccharide (LPS) liver damage lung M. leprae M. tuberculosis metabolic alterations metabolic reprograming metabolic syndrome microglia micronutrients miRNA molecular docking mycobacteria n/a neural stem cells neurogenesis neuroinflammation neuropathology nitric oxide synthase non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) nonalcoholic fatty liver disease (NAFLD) norepinephrine nuclear factors nuclear receptor nuclear receptors nucleus accumbens nutrigenomics obesity oleoylethanolamide P2Y2 receptor palmitoylethanolamide pattern-recognition receptors pemafibrate peroxisome peroxisome proliferator-activated receptor peroxisome proliferator-activated receptor alpha peroxisome proliferator-activated receptor gamma (PPARγ) peroxisome proliferator-activated receptors (PPAR) peroxisome-proliferator-activated receptor phagocytosis pharmacological targets PPAR PPAR gamma PPARg PPARs PPARα PPARα knockout PPARβ/δ PPARγ PPARγ ligand PPRE proliferation psoriasis pulmonary arterial hypertension pulmonary artery quercetin real-time PCR regulatory T cells resveratrol retinal ischemia screening sex dimorphism signaling pathway skeletal muscle subgenual prefrontal cortex substrate metabolism TGFβ toll-like receptor 4 type 2 diabetes mellitus vascular injury X-ray crystallography Zika β-oxidation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576873703321 |
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Vázquez-Carrera Manuel
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthesis of Flavonoids or Other Nature-Inspired Small Molecules
| Synthesis of Flavonoids or Other Nature-Inspired Small Molecules |
| Autore | Ribaudo Giovanni |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (82 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
(+)-camphor
1,2,3-triazole 7-hydroxy-2H-chromen-2-one ADMET aminoquinoline anticancer anticonvulsant activity antidiabetic benzylidene derivative C. dichotoma Clusiaceae coumarin curcumin analog DFT calculation docking flavonoids Garcinia porrecta hybrid compound hydrazone kokosanolide Lansium domesticum lupeol derivative MCF-7 Meliaceae molecular modeling n/a O-acylation reaction organic synthesis Oxone® PDE photophysical properties quercetin semi-synthetic sildenafil steady-state fluorescence technology terpenoid tetranortriterpenoid triterpene onoceranoid valproic acid xanthone α-amylase α-glucosidase α-glucosidase inhibition |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557615703321 |
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Ribaudo Giovanni
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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