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Botulinum Neurotoxins and Nervous System : Future Challenges for Novel Indications
| Botulinum Neurotoxins and Nervous System : Future Challenges for Novel Indications |
| Autore | Luvisetto Siro |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
botulinum toxin
limb tremors muscle selection biological effect various cell types neurotransmitter dermatology novel indication botulinum neurotoxin masticatory system maxillofacial bone dental occlusion orthognathic surgery sialorrhoea drooling salivary glands swallowing eccrine glands onabotulinumtoxin A incobotulinumtoxin A botulinum neurotoxins botulinum neurotoxin serotype A heavy chain botulinum neurotoxin serotype a heavy chain (BoNT/A HC) spinal cord injury (SCI) nerve regeneration growth associated protein 43 (GAP-43) superior cervical ganglion 10 (SCG10) neuronal processes neural regeneration Schwann cells glia spinal cord immunohistochemistry allodynia weight bearing sciatic static index walking track analysis itch SNARE VAMP mast cells compound 48/80 chloroquine spasticity botulinum toxin type A appropriate treatment Therapeutic Index pruritus antipruritic clinical experimental BoNT/A astroglia interleukins microglia TLR2 TLR4 Snap-23 pain cerebral palsy botulinum toxin A complex regional pain syndrome lumbar sympathetic ganglion block chronic pelvic pain overactive detrusor vaginism temporomandibular joint dislocation lateral pterygoid muscle botulinum toxin therapy synaptic transmission SNAP-25 epilepsy Parkinson's disease neurotransmission blockade electrical activity prion disease new indications formulation delivery refractory chronic migraine tension headache medication overuse headache prophylactic treatment XEOMIN® BTX central neuropathic pain spinal cord injury post-stroke shoulder pain mouse test Clostridium tetani botulinum antitoxin food safety abobotulinumtoxinA upper limb spasticity post-stroke early use ONTIME clinical trial human urodynamics botulinum neurotoxin-A basal ganglia interspecies differences in motor behavior mouse rat interneurons hand tremor treatment electromyography kinematics essential tremor dystonic tremor tremor movement disorders Botulinum toxin upper limb biomechanics joint biomechanics diagnostic guidance clinical decision support spastic paresis electrical stimulation stroke management rehabilitation hand |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Botulinum Neurotoxins and Nervous System |
| Record Nr. | UNINA-9910557109003321 |
Luvisetto Siro
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transmucosal Absorption Enhancers in the Drug Delivery Field
| Transmucosal Absorption Enhancers in the Drug Delivery Field |
| Autore | Maher Sam |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (406 p.) |
| Soggetto non controllato |
chitosan
intestinal epithelial cells ocular delivery amphiphilic polymers cornea tight junction modulator cyclodextrin permeability gemini surfactant transferrin compound 48/80 epithelial permeability cervicovaginal tumors nanoparticles confocal laser scanning microscopy safety formulation salcaprozate sodium intestinal absorption FITC-dextran curcumin block copolymers nasal vaccination whole leaf brush border ocular drug delivery vaccine adjuvant nanoparticle nasal delivery efflux permeation enhancers absorption enhancers nose to brain delivery small intestine epithelium CNS disorders absorption modifying excipients insulin absorption enhancer gel intestinal delivery thermogel system Caco-2 biocompatibility studies absorption enhancement man PN159 poorly absorbed drug tryptophan tight junction oral macromolecule delivery penetration enhancer intestinal permeation enhancers nanocrystals simvastatin nanomedicine enterocyte N-dodecyl-?-D-maltoside (DDM) cell-penetrating peptide quaternization KLAL nasal nasal permeability transmucosal drug delivery Caco-2 cells mast cell activator penetration enhancers drug delivery nose-to-brain bioenhancer polymeric micelles mucoadhesion cell-penetrating peptide (CPP) simulated intestinal fluid vaginal delivery nasal formulation pharmacokinetic interaction sodium caprate clinical trial transmucosal permeation drug absorption enhancer sugar-based surfactants nanocapsules imatinib teriparatide osteoporosis hydrophobization F-actin combined microsphere transepithelial electrical resistance oral delivery ocular conditions metabolism antimicrobial peptide permeation enhancer drug administration antiepileptic drug amino acid in vivo studies sodium cholate (NaC) epithelial transport preclinical nose to brain transport pharmacokinetics chitosan derivatives ophthalmology tight junctions sheep cationic functionalization GLP-1 pulmonary and liposome cytochrome P450 claudin P-glycoprotein in situ hydrogel mucoadhesiveness PTH 1-34 Aloe vera oral peptides |
| ISBN | 3-03921-849-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910372785603321 |
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Maher Sam
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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