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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (606 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
benzofurans
chemical synthesis cytotoxic properties HeLa MOLT-4 K562 anticancer anti-neuroinflammation coumarin dihydroartemisinin flavonoids allene E-stereoselective regioselective anti-cancer activity cyanopyridone substituted pyridine pyridotriazine pyrazolopyridine thioxotriazopyridine anticancer activity HepG2 antitumor activity computational docking MDM2-p53 interaction xanthones yeast-based assays estrone derivatives hydrazine N-substituted pyrazoline anti-ovarian cancer topoisomerase II inhibitor kinase inhibitor antiproliferative agent urea synthesis antiproliferative activity apoptosis indoleamine 2,3-dioxygenase inhibitor anti-tumor immune modulation tryptophan metabolism taxoids βIII-tubulin P-glycoprotein drug resistance thiopene thienopyrimidinone thiazolidinone breast cancer benzofuran–pyrazole nanoparticles cytotoxic activity PARP-1 inhibition 3,6-dibromocarbazole 5-bromoindole carbazole actin migration Thienopyrimidine Pyrazole PI3Kα inhibitor quinazolin-4(3H)-one quinazolin-4(3H)-thione Schiff base antioxidant activity DFT study ortho-quinones beta-lapachone tanshione IIA PI3Ks PI3Kδ inhibitors 2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide anticancer agents protein–protein interactions virtual screening mimetics drug discovery bivalency polyvalency antitumor cell cycle ovarian cancer P-MAPA IL-12 TLR signaling inflammation chemoresistance 4-(pyridin-4-yloxy)benzamide 1,2,3-triazole c-Met natural product anticancer agent zampanolide Talazoparib PARP inhibitor prodrug o-nitro-benzyl photoactivatable protecting groups salinomycin overcoming drug resistance tumor specificity synergy 5-fluorouracil gemcitabine amides/esters colchicine analogs thiocolchicine colchiceine antimitotic agents hydrates dihydropyranoindole HDAC inhibitors neuroblastoma aromatase MCF-7 NIH3T3 benzimidazole triazolothiadiazine docking ADME organosilicon compounds SILA-409 (Alis-409) SILA-421 (Alis-421) multidrug resistance (MDR) reversal ABCB1 (P-glycoprotein) colon cancer colchicine amide colchicine sulfonamide tubulin inhibitors docking studies crystal structure PROTACs protein degradation IGF-1R Src protein kinase phenylpyrazolopyrimidine enzyme inhibition molecular simulation androgen receptor prostate cancer enzalutamide apalutamide darolutamide triple-negative breast cancer cytotoxicity chrysin analogues flavonoid anticancer compounds |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biogenic Amines on Food Safety
| Biogenic Amines on Food Safety |
| Autore | Ruiz-Capillas Claudia |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto non controllato |
catecholamines
radish kimchi Chonggak kimchi cheese biogenic amines herby cheese Kkakdugi serotonin screening method storage conditions putrescine quality control decarboxylase enzymes food products iodine feed intervention methods bowel diseases tyramine decarboxylase activity plant-origin foods nutrition high hydrostatic pressure Lactobacillus brevis physico-chemical composition artisanal cheese free amino acid histamine gastrointestinal tract culinary process meat species food quality Bacillus spp inflammation fermented soybean foods quality index polyamines HPLC public health cadaverine gastric cancer kimchi colon cancer quality indexes control lactic acid bacteria legislation–regulation food safety raw milk cheese starter cultures analytical determination histamine intolerance low-histamine diet starter culture |
| ISBN | 3-03921-055-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346851103321 |
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Ruiz-Capillas Claudia
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Immunology
| Cancer Immunology |
| Autore | Subramanian Subree |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (316 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
NKG2D
CAR T IL-7 prostate cancer cell therapy CD19-CAR-T B cell aplasia KIR PD-1 inhibitory CAR tumor-infiltrating lymphocytes tumor microenvironment immunotherapy NK cells cancer stem cells (CSCs) antibody-dependent cellular cytotoxicity (ADCC) differentiation cytotoxicity IFN-γ osteoclasts MICA/B mAb DNA methylation RNA methylation S-adenosylmethionine (SAM) cancer innate immunity adaptive immunity T cells m6A PD-L1 resistance immune checkpoints cancer vaccine combination immunotherapy TCR diversity organ transplantation carcinoma epidemiologic studies immunosuppression CTLA-4 Treg cells immune checkpoint inhibitors CD28 antigen-presenting cells IL15 colon cancer melanoma uveal BAP1 anti-PD-1 anti-CTLA-4 TIL classical and endemic Kaposi Sarcoma systemic treatment multi-state modelling treatment free interval chemotherapy interferon triple negative breast cancer immunomodulation bispecific antibody sortase A chemo-enzymatic approach anti-CD20 antibody Fab BiFab colorectal cancer dendritic cells Atypical Chemokine Receptor 4 (ACKR4) T-cell priming immune checkpoint blockade primary liver cancer kynurenine pathway immune evasion indoleamine 2,3 dioxygenase 1 tryptophan 2,3 dioxygenase 2 IDO inhibitor antigen presenting cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557349203321 |
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Subramanian Subree
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Colorectal Cancers: From Present Problems to Future Solutions
| Colorectal Cancers: From Present Problems to Future Solutions |
| Autore | Allgayer Heike |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (238 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
Phage
bacteriophages diet infection colorectal cancer nutrition circulating tumor cells colorectal cancer EPISPOT assay CellSearch® system predictive value chromatin density nanoscale tumour cell heterogeneity microRNAs metastasis super-resolution microscopy early onset cohort epidemiology liquid biopsy biomarker indirect carcinogenesis bovine meat and milk factors (BMMF) chronic zoonosis multiplex tumor immunology immune landscape spontaneous feline intestinal tumors comparative oncology tumor budding CTNNB1 genome-wide methylation array methylation miRNA colon cancer personalized treatment drug combinations Matrix Metalloproteinases (MMPs) polyp TIMPs MMP polymorphisms MMP targeting S100A4 DKK1 Wnt signaling patient survival gender rectal cancer radiochemotherapy radiosensitivity DNA double-strand breaks deposited energy quality of life blood values (molecular) carcinogenesis cancer progression (single) cancer cell heterogeneity models infectious agents (targeted) therapy personalized medicine |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Colorectal Cancers |
| Record Nr. | UNINA-9910585937103321 |
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Allgayer Heike
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Deep Learning in Medical Image Analysis
| Deep Learning in Medical Image Analysis |
| Autore | Zhang Yudong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (458 p.) |
| Soggetto non controllato |
interpretable/explainable machine learning
image classification image processing machine learning models white box black box cancer prediction deep learning multimodal learning convolutional neural networks autism fMRI texture analysis melanoma glcm matrix machine learning classifiers explainability explainable AI XAI medical imaging diagnosis ARMD change detection unsupervised learning microwave breast imaging image reconstruction tumor detection digital pathology whole slide image processing multiple instance learning deep learning classification HER2 medical images transfer learning optimizers neo-adjuvant treatment tumour cellularity cancer breast cancer diagnostics imaging computation artificial intelligence 3D segmentation active surface discriminant analysis PET imaging medical image analysis brain tumor cervical cancer colon cancer lung cancer computer vision musculoskeletal images lung disease detection taxonomy convolutional neural network CycleGAN data augmentation dermoscopic images domain transfer macroscopic images skin lesion segmentation infection detection COVID-19 X-ray images bayesian inference shifted-scaled dirichlet distribution MCMC gibbs sampling object detection surgical tools open surgery egocentric camera computers in medicine segmentation MRI ECG signal detection portable monitoring devices 1D-convolutional neural network medical image segmentation domain adaptation meta-learning U-Net computed tomography (CT) magnetic resonance imaging (MRI) low-dose sparse-angle quantitative comparison |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557435103321 |
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Zhang Yudong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Diagnosis and Treatment of Small Bowel Disorders
| Diagnosis and Treatment of Small Bowel Disorders |
| Autore | Koulaouzidis Anastasios |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (146 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
capsule endoscopy
Crohn's disease mucosal healing small bowel gut brain axis microbiota functional gastrointestinal disorders inflammatory bowel disease (IBD) adult stem cells surgical site infections (SSIs) probiotics prebiotics synbiotics surgery adverse events meta-analysis systematic review hyperspectral imaging multispectral imaging clinical diagnosis biomedical optical imaging gastroenterology medical diagnostic imaging small-bowel mass small-bowel bulge video capsule endoscopy cystic fibrosis gut microbiota intestinal inflammation fecal calprotectin dysbiosis index celiac disease biomarker serology enteropathy colon cancer cancer risk collagenous colitis lung cancer microscopic colitis skin cancer squamous cell carcinoma |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557118003321 |
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Koulaouzidis Anastasios
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Gastrointestinal Cancers and Personalized Medicine
| Gastrointestinal Cancers and Personalized Medicine |
| Autore | Mini Enrico |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (136 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
neutrophil-to-lymphocyte ratio
lymphocyte-to-monocyte ratio prognosis rectal cancer mesorectum sphincter preserving molecular oncology precision medicine colorectal cancer targeted therapy molecular profiling pancreatic cysts thermal liquid biopsy differential scanning calorimetry diagnosis generalized linear models gene signature mRNA expression VANGL1 FFPE neurotoxicity oxaliplatin chemotherapy-induced peripheral neuropathy biomarker genomics neuropathy FOLFOX FOLFIRINOX XELOX gastrointestinal cancer LAG-3 immune checkpoint colon cancer survival microsatellite instability immunotherapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566485503321 |
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Mini Enrico
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application
| In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application |
| Autore | Baiocchi Marta |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (222 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Microbiology (non-medical) |
| Soggetto non controllato |
colorectal cancer
organoids 3D bioprinting patient-derived xenograft cancer-on-chip drug combination cancer stem cells drug resistance clinical trials tumor-initiating cells tumor heterogeneity patient-derived cancer models single-cell RNA-sequencing tumor metabolism transcriptional programs tumor cell differentiation immunotherapy methods chromosomal instability DNA damage targeted therapy decitabine colon cancer DNA methylation clinical translation study machine learning patient-derived tumor organoid precision medicine radiation response rectal cancer PDX model CRC mutation analysis histological examination animal models in vitro culture cancer stem cell methods SATB2 colorectal carcinoma prognosis CDX2 circulating tumor cells CTC cluster size-based method ScreenCell® epithelial mesenchymal transition hypoxia HIF-1α immunofluorescence analysis sequential filtration |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585944103321 |
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Baiocchi Marta
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Machine Learning/Deep Learning in Medical Image Processing
| Machine Learning/Deep Learning in Medical Image Processing |
| Autore | Nishio Mizuho |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (132 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
pancreas
segmentation computed tomography deep learning data augmentation neoplasm metastasis ovarian neoplasms radiation exposure tomography x-ray computed prostate carcinoma microscopic convolutional neural network machine learning handcrafted oral carcinoma medical image segmentation colon cancer colon polyps OCT optical biopsy animal rat models CADx airway volume analysis artificial intelligence coronary artery disease SPECT MPI scans convolutional neural networks transfer learning classification models |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557791503321 |
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Nishio Mizuho
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metastatic Progression and Tumour Heterogeneity
| Metastatic Progression and Tumour Heterogeneity |
| Autore | Hollande Fred |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (312 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
clear cell renal cell carcinoma
tumor evolution tumor ecology intratumor heterogeneity multisite tumor sampling targeted therapy uterine carcinosarcoma endometrial carcinoma metaplastic carcinoma epithelial-to-mesenchymal transition clonality mutation TP53 PI3K/AKT pathway gene expression miRNA expression tumor microenvironment interstitial pH acidosis tumor heterogeneity magnetic resonance imaging hyperpolarized 13C MRI carbonic anhydrase lactic acid positron emission tomography esophageal squamous cell carcinoma precision medicine natural killer cells tumor mutation burden immunotherapy PET heterogeneity radiomics radiopharmaceuticals SUV nuclear medicine colon cancer Wnt signaling phenotypic plasticity EMT hybrid E/M collective and single-cell migration beta-catenin paradox breast cancer immune microenvironment DCIS ADH mammary gland cell fate 3D cultures organoids signaling single-cell RNAseq tumor endothelial cell metastasis angiocrine factor microsatellite instability colorectal cancer immune checkpoints deficient mismatch repair plasticity biomechanics circulating tumor cells (CTCs) extracellular vesicles metastatic niche epigenetics CTC-clusters single-cell analysis cellular heterogeneity circulating tumor cells pancreatic cancer epithelial mesenchymal plasticity target discovery review genomics intra-tumour heterogeneity subclonal diversity treatment resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557105803321 |
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Hollande Fred
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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