Bioactive Natural Products from the Red Sea |
Autore | Rateb Mostafa |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (152 p.) |
Soggetto topico | Research & information: general |
Soggetto non controllato |
Aspergillus falconensis
OSMAC azaphilones X-ray diffraction NF-κB inhibition LC-HRESIMS Stylissa carteri ceramide cerebroside docking cytotoxic activity co-cultivation phenazine sponge-associated actinomycetes antibacterial antibiofilm DNA gyrase pyruvate kinase ergosterol derivative metabolic analysis docking studies seagrass Thalassodendron ciliatum Red Sea sponges marine actinomycetes Streptomyces coelicolor LY001 halogenated 3-phenylpropanoic acid derivatives diketopiperazine alkaloids structural determinations antimicrobial activities Red Sea marine natural products marine organisms biodiversity marine metagenomics bioactivity Sinularia polydactyla soft coral steroids cytotoxic anti-inflammatory neuroprotective androgen receptor Actinokineospora Rhodococcus co-culture metabolomics antimalarial epicotripeptin phragamide Epicoccum Alternaria antimicrobial |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557540903321 |
Rateb Mostafa | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cells and Materials for Disease Modeling and Regenerative Medicine |
Autore | Abarrategi Ander |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (270 p.) |
Soggetto topico | Research & information: general |
Soggetto non controllato |
Leigh syndrome
mitochondrial disorder iPSC NSC neuron disease modeling mtDNA high hydrostatic pressure devitalization decellularization allografts regenerative medicine bone and cartilage regeneration dentogenesis amelogenesis dentinogenesis cementogenesis drug release materials scaffolds odontogenic cells stem cells whole-tooth regeneration psoriasis cyclic adenosine monophosphate cholera toxin isoproterenol tissue engineering extracellular matrix collagen elastin bladder compliance microarchitecture biomimicry blood cancer bone marrow niche microenvironment 3D models tumor-on-a-chip leukemia myeloma biomaterials cytokines growth factors cardiac tissue regeneration adipose tissue fibrosis in vitro models in vivo models dental pulp stem cells osteogenesis rheumatoid arthritis mesenchymal stromal cells co-culture 3D cell culture explants joint-on-a-chip piezoelectric electroactive patterning cell differentiation bone tissue engineering |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557403303321 |
Abarrategi Ander | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Marine Microbial Diversity as Source of Bioactive Compounds |
Autore | Shaaban Khaled A |
Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
Descrizione fisica | 1 electronic resource (182 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
co-culture
marine microbes natural products structural diversity biological activities food allergy deep-sea-derived viridicatol X-ray single crystal intestinal barrier mast cell calcium influx Chlorella enzymes lipases molecular modeling sulfated polysaccharides antiviral SARS-CoV-2 docking molecular dynamic simulations sea cucumber bioactivity diversity microorganism polyketides alkaloids marine-derived fungus Penicillium sp indole-diterpenoids cytotoxicity antibacterial activity Leizhou Peninsula mangrove soil actinomycetia antimicrobial activity secondary metabolites dereplication metabolomics tools trioxacarcins mansouramycins isoquinolinequinones marine-derived Streptomyces sp |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910595068803321 |
Shaaban Khaled A | ||
Basel, : MDPI Books, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Microfluidics for Cells and Other Organisms |
Autore | van Noort Danny |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
Descrizione fisica | 1 electronic resource (200 p.) |
Soggetto non controllato |
screening
microfluidic device cell homogenous dispersion structure RNA biomedical engineering neural networks single-cell mechanics on-chip cell incubator cell growth embryogenesis cancer stem cell intracellular proteins simultaneous multiple chamber observation instrumentation fnRBC cancer metastasis Wheatstone bridge capillary single-cell manipulation adherent cells nucleic acid micropipette aspiration sample preparation unsupervised learning cell motility capture efficiency bacterial concentration cbNIPD microfabrication drug resistance variational inference microfluidics periodic hydrostatic pressure paracrine signaling periodic pressure capacitively coupled contactless conductivity detection (C4D) bioMEMS microfluidic flow cytometry particle/cell imaging co-culture cells-in-gels-in-paper laminar flows E. coli printed-circuit-board (PCB) pneumatic microvalve time-lapse observation nanostructure 3D particle focusing target cell-specific binding molecules absolute quantification DNA zebrafish embryo microscopy 3D printing 3D flow focusing single-cell analysis |
ISBN | 3-03921-563-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910367750803321 |
van Noort Danny | ||
MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
The Tight Junction and Its Proteins : More Than Just a Barrier |
Autore | Fromm Michael |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (432 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
tissue barrier
tight junction claudins tricellulin tight junctions organ preservation intestine transplantation ischemia intestinal mucosa lung epithelia interleukin 13 UBE2Z ubiquitin osmolality hydrostatic pressure cancer sensor tricellular tight junctions endometrial cancer epithelial barrier dysfunction Claudin-7 permeability WNK4 epithelial sodium channel (ENaC), collecting duct cells claudin-1 hydrogen peroxide phosphorylation claudin angulin drug development angubindin-1 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin antibody Mz-ChA-1 cells biliary epithelial cells phosphatidylcholine mucus paracellular transport atopic dermatitis cytokines STAT3 ZO-2 cholestasis gene transcription hypertrophy tumor suppressor NLS NES CaSR RhoA barrier function paracellular permeability antidiuretic hormone Claudin-14 CLDN14 hearing loss vestibular function cochlear implantation Hepatitis C Virus viral entry epidermal barrier reconstructed human epidermis claudin targeting Campylobacter jejuni curcumin apoptosis co-culture mouse colon TNF NFκB lipolysis-stimulated lipoprotein receptor (LSR) epithelial barrier cell–cell contact caspase kidney stones ion reabsorption quercetin brain barriers blood-brain barrier neurovascular unit blood-cerebrospinal fluid barrier arachnoid barrier glia limitans adherens junctions paracellular sodium transport thick ascending limb nephropathy HELIX syndrome hypokalemia hypermagnesemia anhidrosis gland dysfunction aging blood–brain barrier mutations kidney liver skin human mice disease in silico drug discovery membrane proteins protein interactions molecular dynamics antibiotic-associated hemorrhagic colitis Klebsiella oxytoca tight junction assembly monocytes celiac disease claudin-2 epithelium inflammation fibrosis proliferation migration tricellular tight junction paracellular water transport tight epithelium MDCK C7 cells cell growth endothelia adherens junction apical junctional complex AMP-activated protein kinase (AMPK) paracellular barrier protein structure protein domain occludin junctional adhesion molecule zonula occludens MAGUK proteins PDZ domain stem cell chemoresistance retinal pigment epithelium retinopathy barrier formation collecting duct claudin-5 neuropathic pain nerve injury dorsal root ganglion enteropathogenic E. coli (EPEC) tight junctions (TJ) polarity atypical aPKCζ transepithelial electrical resistance (TER) sorting nexin 9 (SNX9) EspF claudin 1 tumor metastasis epithelial to mesenchymal transition cerebral cavernous malformation endothelial barrier Rho ROCK MEKK3 ion transport ion channel super-resolution microscopy structured illumination microscopy stimulated emission depletion single molecule localization microscopy Claudin blood-biliary barrier chronic liver disease hepatocellular carcinoma cholangiocellular carcinoma NISCH syndrome repair NHE2 ClC-2 inflammatory bowel disease mucosal immunology ZO-1 actomyosin aquaporin drinking rate epithelial fluid transport enterocyte osmoregulation paracellular proximal tubule calcium permeability claudin-12 paracellular channels and barriers cell polarity pathogens immune cells environmental sensors |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Tight Junction and Its Proteins |
Record Nr. | UNINA-9910557404603321 |
Fromm Michael | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier |
Autore | Fromm Michael |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (412 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
tissue barrier
tight junction claudins tricellulin tight junctions organ preservation intestine transplantation ischemia intestinal mucosa lung epithelia interleukin 13 UBE2Z ubiquitin osmolality hydrostatic pressure cancer sensor tricellular tight junctions endometrial cancer epithelial barrier dysfunction Claudin-7 permeability WNK4 epithelial sodium channel (ENaC), collecting duct cells claudin-1 hydrogen peroxide phosphorylation claudin angulin drug development angubindin-1 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin antibody Mz-ChA-1 cells biliary epithelial cells phosphatidylcholine mucus paracellular transport atopic dermatitis cytokines STAT3 ZO-2 cholestasis gene transcription hypertrophy tumor suppressor NLS NES CaSR RhoA barrier function paracellular permeability antidiuretic hormone Claudin-14 CLDN14 hearing loss vestibular function cochlear implantation Hepatitis C Virus viral entry epidermal barrier reconstructed human epidermis claudin targeting Campylobacter jejuni curcumin apoptosis co-culture mouse colon TNF NFκB lipolysis-stimulated lipoprotein receptor (LSR) epithelial barrier cell–cell contact caspase kidney stones ion reabsorption quercetin brain barriers blood-brain barrier neurovascular unit blood-cerebrospinal fluid barrier arachnoid barrier glia limitans adherens junctions paracellular sodium transport thick ascending limb nephropathy HELIX syndrome hypokalemia hypermagnesemia anhidrosis gland dysfunction aging blood–brain barrier mutations kidney liver skin human mice disease in silico drug discovery membrane proteins protein interactions molecular dynamics antibiotic-associated hemorrhagic colitis Klebsiella oxytoca tight junction assembly monocytes celiac disease claudin-2 epithelium inflammation fibrosis proliferation migration tricellular tight junction paracellular water transport tight epithelium MDCK C7 cells cell growth endothelia adherens junction apical junctional complex AMP-activated protein kinase (AMPK) paracellular barrier protein structure protein domain occludin junctional adhesion molecule zonula occludens MAGUK proteins PDZ domain stem cell chemoresistance retinal pigment epithelium retinopathy barrier formation collecting duct claudin-5 neuropathic pain nerve injury dorsal root ganglion enteropathogenic E. coli (EPEC) tight junctions (TJ) polarity atypical aPKCζ transepithelial electrical resistance (TER) sorting nexin 9 (SNX9) EspF claudin 1 tumor metastasis epithelial to mesenchymal transition cerebral cavernous malformation endothelial barrier Rho ROCK MEKK3 ion transport ion channel super-resolution microscopy structured illumination microscopy stimulated emission depletion single molecule localization microscopy Claudin blood-biliary barrier chronic liver disease hepatocellular carcinoma cholangiocellular carcinoma NISCH syndrome repair NHE2 ClC-2 inflammatory bowel disease mucosal immunology ZO-1 actomyosin aquaporin drinking rate epithelial fluid transport enterocyte osmoregulation paracellular proximal tubule calcium permeability claudin-12 paracellular channels and barriers cell polarity pathogens immune cells environmental sensors |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Tight Junction and Its Proteins |
Record Nr. | UNINA-9910674057303321 |
Fromm Michael | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday: Natural Products in Modern Drug Discovery |
Autore | Hussain Hidayat |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (360 p.) |
Soggetto topico |
Research & information: general
Chemistry Organic chemistry |
Soggetto non controllato |
multi-component reaction
fusidic acid TEMPO-conjugate electron paramagnetic resonance (EPR) spectroscopy caspase-3 incomptine A sesquiterpene lactone Decachaeta incompta cytotoxic activity iTRAQ apoptosis ROS production violacein hepatocellular carcinoma proliferation stemness natural products tumor microenvironment (TME) lung cancer phytochemicals botanical agents steroidal alkaloids solanidane alkaloids demissidine solanidine flavonoids coronavirus SARS-CoV-2 SARS-CoV MERS-CoV anticancer activity apoptosis resistance ophiobolin A polygodial Wittig reaction melanoma tumor heterogeneity pregnancy anti-tumor peptides in vitro model medicinal herbs cancer treatment cancer stem cells drug resistance metastasis RCE-4 PCD ATG 4B the Bcl-2-Beclin 1 complex Sparticola junci structure elucidation ECD-TDDFT COX inhibitory molecular docking antiproliferative cytotoxic Sepedonium ampullosporum peptaibols ampullosporin glutamic acid methyl ester solid-phase peptide synthesis antifungal anticancer target identification kaempferol docking DARTS Src breast cancer butein frondoside-A STAT3 angiogenesis invasion viability tumor growth marine fungi Cosmospora sp soudanone Magnaporthe oryzae co-culture phytopathogen molecular networking metabolomics bispecific antibody Trypsiligase click chemistry biorthogonal chemistry antibody engineering |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday |
Record Nr. | UNINA-9910585945403321 |
Hussain Hidayat | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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