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From a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential
| From a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential |
| Autore | Ribaudo Giovanni |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (234 p.) |
| Soggetto topico |
Medicine and Nursing
Pharmacology |
| Soggetto non controllato |
3-chymotrypsin-like protease
affinity chromatography alginate anti-ACE anti-DPP-IV anti-inflammatory drugs antioxidant activity benzoic acid derivatives big data binding free energy Box-Behken breast milk cannabinoid chemoinformatics chromatographic descriptors cisplatin clopidogrel coronavirus SARS-CoV-2 COVID-19 cyclooxygenase cytoprotection DFT calculations drug compounding drug discovery E-selectin Eucheuma gelatinae extraction fucoidan gallic acid gastrointestinal digestion high performance liquid chromatography ICAM-1 imine-enamine in silico L-selectin lithium therapy M/P ratio MCP-1 methadone hydrochloride microbiology molecular descriptors molecular docking molecular dynamics molecular dynamics simulations monocyte migration multitarget drug n/a nephrotoxicity neurocytology neuropathic pain neuroprotection NMR study one-pot oxone pain management paramyosin peroxymonosulfate pharmaceutical solutions pharmacodynamics pharmacokinetics physic-chemistry precision medicine protein binding pyrimidonic pharmaceuticals QSAR quercetin quercetin 3-O-glucuronide reaction mechanism reactivity parameters rheology SARS-CoV-2 seafood selenium selenoxide elimination sodium halide stability study statistical modeling target fishing thienopyridine THP-1 macrophage toxicology β-carrageenan |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | From a Molecule to a Drug |
| Record Nr. | UNINA-9910585940503321 |
Ribaudo Giovanni
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmacogenetics to Avoid Adverse Drug Reactions
| Pharmacogenetics to Avoid Adverse Drug Reactions |
| Autore | López-Fernández Luis A |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (220 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
(es)citalopram
5-fluorouracil acute coronary syndrome adverse drug reactions adverse events allele anti-epileptic drugs (AEDS) antiepileptics antipsychotic agents atorvastatin capecitabine cardiology cardiovascular disease clinical implementation clopidogrel colorectal cancer cutaneous adverse drug reaction cutaneous adverse drug reactions (CADRs) CYP2C9*3 CYP450 enzymes cytochrome P-450 enzyme system direct oral anticoagulants drug-drug-gene-interaction drug-drug-interaction drug-gene-interaction epistasis fluoropyrimidine genetic polymorphism genetic risk factors genotype guidelines HLA HLA B India n/a personalised medicine pharmacogenetics pharmacogenomics phenytoin (PHT) platelet reactivity polymorphism precision medicine psychotic disorders random forest SCAR single-nucleotide variants SLCO1B1 South India statin the PharmLines initiative thymidylate synthase thymidylate synthase enhancer region toxicity upstream stimulatory factor 1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557610103321 |
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López-Fernández Luis A
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmacogenomics and Personalized Medicine
| Pharmacogenomics and Personalized Medicine |
| Autore | Cecchin Erika |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (208 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
acenocoumarol
alleles AML azathioprine breast cancer subtype CDSS childhood acute lymphoblastic leukemia cisplatin clopidogrel crosstalk network CYP2C9 drug resistance focal copy number alterations gene expression genetic polymorphisms genotype glutathione-S transferase high-throughput analysis human genetics implementation inflammatory bowel disease INR kidney injury microRNAs miRNA nephrotoxicity nucleoside analogs ovarian cancer panel pathway personalized medicine pharmacogenetics pharmacogenetics study pharmacogenomics pharmacokinetics pharmacology pharmacotranscriptomics phenotype platinum resistance pre-emptive precision drugs precision medicine VKORC1 warfarin warfarin initiation phase of therapy whole exome sequencing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557287703321 |
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Cecchin Erika
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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