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Advances in DNA Vaccines
| Advances in DNA Vaccines |
| Autore | Isaguliants Maria |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (210 p.) |
| Soggetto topico |
Medicine
Epidemiology & medical statistics |
| Soggetto non controllato |
alphaviruses
layered RNA/DNA vectors DNA vaccines RNA replicons recombinant particles tumor regression protection against tumor challenges and infectious agents ebola virus disease artificial T-cell antigens DNA vaccine constructs computer design gene expression immunogenicity DNA vaccine mRNA vaccine plasmid DNA in vitro transcribed mRNA immune responses formulations Cytolytic T Lymphocytes antibodies innate immunity adjuvants vaccine delivery plasmid cytolytic perforin bicistronic HCV HIV IL-36 adjuvant DNA Zika Epstein-Barr virus latent proteins LMP2 EBNA1 LMP1 HIV-1 enhancer element circovirus influenza immunization intranasal lipid flagellin BCG vaccine rBCG HTI T-cell AIDS clinical trial therapeutic vaccine hepatitis C virus (HCV) mesenchymal stem cells (MSC) modified MSC DNA immunization nonstructural HCV proteins immune response HCV vaccine myeloid derived suppressor cells (MDSCs) |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557354503321 |
Isaguliants Maria
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Eating Disorders
| Advances in Eating Disorders |
| Autore | Aguera Zaida |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (348 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
anorexia nervosa
cognitive interpersonal model severe enduring physical activity accelerometry weight gain eating disorders malnutrition neuroimaging fractal dimension cortical complexity food craving food addiction emotion regulation event related potentials EEG neurophysiology psychopathology ASD comorbidity emotion recognition attention sensory sensitivity autism Avon Longitudinal Study of Parents and Children (ALSPAC) body mass index disordered eating behaviors disordered eating cognitions polygenic scores non-suicidal self-injury temperament eating disorder adolescence nocturnal eating syndrome sleep-related eating disorder parasomnia delayed sleep-wake phase MUPS magnetic resonance spectroscopy MRS insula glutamate N-acetylaspartate NAA epigenetics bulimia nervosa DNA methylation gene-environment interactions caloric intake refeeding syndrome refeeding protocol children and adolescents parents carers intervention workshop online intervention alcohol and/or drug abuse substance use disorder executive functions impulsivity emotional dysregulation deep brain stimulation psychosurgery clinical trial subcallosal cingulate nucleus accumbens high expressed emotion caregivers dance students disordered eating attitudes Eating Attitudes Test-26 (EAT-26) mesomorphy ectomorphy Receiver Operating Characteristics (ROC) curve analysis attention-deficit/hyperactivity disorder ADHD longitudinal treatment outcome dropout rTMS treatment anorexia bulimia binge eating disorders restrictive anorexia nervosa weight recovery animal models acyl-ghrelin desacyl-ghrelin chronic food restriction virtual reality fear of gaining weight body anxiety body image disturbances body-related attentional bias |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557561003321 |
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Aguera Zaida
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bayesian Design in Clinical Trials
| Bayesian Design in Clinical Trials |
| Autore | Berchialla Paola |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (190 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
dose-escalation
combination study modelling assumption interaction adaptive designs adaptive randomization Bayesian designs clinical trials predictive power target allocation Bayesian inference highest posterior density intervals normal approximation predictive analysis sample size determination bayesian meta-analysis clustering binary data priors frequentist validation Bayesian rare disease prior distribution meta-analysis sample size bridging studies distribution distance oncology phase I dose-finding dose–response bayesian inference prior elicitation latent dirichlet allocation clinical trial power-prior poor accrual Bayesian trial cisplatin doxorubicin oxaliplatin dose escalation PIPAC peritoneal carcinomatosis randomized controlled trial causal inference doubly robust estimation propensity score Bayesian monitoring futility rules interim analysis posterior and predictive probabilities stopping boundaries Bayesian trial design early phase dose finding treatment combinations optimal dose combination |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557608103321 |
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Berchialla Paola
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Phytochemicals in Health and Disease
| Bioactive Phytochemicals in Health and Disease |
| Autore | Iriti Marcello |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (264 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
quercetin
nervous system molecular signals pharmacological potential cognitive impairment micronuclei radioprotectors radiation effects melanoma PNT2 B16F10 cells Ulmus parvifolia wound healing matrix metalloproteinase transforming growth factor skin rejuvenation kaempferol naringin orientin rutin vitexin chlorogenic acid citric acid malic acid quinic acid rosmarinic acid curcumin nanocurcumin neurological disorders nanocarriers liposomes cancer diet flavonoids food supplements hormesis phytoestrogens sulforaphane resveratrol cardiovascular disease nanomedicine liposome nanoformulation RNA-dependent RNA polymerase remdesivir chloroquine SARS-CoV-2 COVID-19 spike glycoproteins Acorus calamus ethnomedicinal phytochemistry toxicity pharmacological action clinical trial neuroprotective neurological metabolic application kurarinone coronavirus HCoV-OC43 autophagy infection MRC-5 cell LC3 p62/SQSTM1 protein |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557389003321 |
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Iriti Marcello
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Botulinum Neurotoxins and Nervous System : Future Challenges for Novel Indications
| Botulinum Neurotoxins and Nervous System : Future Challenges for Novel Indications |
| Autore | Luvisetto Siro |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
botulinum toxin
limb tremors muscle selection biological effect various cell types neurotransmitter dermatology novel indication botulinum neurotoxin masticatory system maxillofacial bone dental occlusion orthognathic surgery sialorrhoea drooling salivary glands swallowing eccrine glands onabotulinumtoxin A incobotulinumtoxin A botulinum neurotoxins botulinum neurotoxin serotype A heavy chain botulinum neurotoxin serotype a heavy chain (BoNT/A HC) spinal cord injury (SCI) nerve regeneration growth associated protein 43 (GAP-43) superior cervical ganglion 10 (SCG10) neuronal processes neural regeneration Schwann cells glia spinal cord immunohistochemistry allodynia weight bearing sciatic static index walking track analysis itch SNARE VAMP mast cells compound 48/80 chloroquine spasticity botulinum toxin type A appropriate treatment Therapeutic Index pruritus antipruritic clinical experimental BoNT/A astroglia interleukins microglia TLR2 TLR4 Snap-23 pain cerebral palsy botulinum toxin A complex regional pain syndrome lumbar sympathetic ganglion block chronic pelvic pain overactive detrusor vaginism temporomandibular joint dislocation lateral pterygoid muscle botulinum toxin therapy synaptic transmission SNAP-25 epilepsy Parkinson's disease neurotransmission blockade electrical activity prion disease new indications formulation delivery refractory chronic migraine tension headache medication overuse headache prophylactic treatment XEOMIN® BTX central neuropathic pain spinal cord injury post-stroke shoulder pain mouse test Clostridium tetani botulinum antitoxin food safety abobotulinumtoxinA upper limb spasticity post-stroke early use ONTIME clinical trial human urodynamics botulinum neurotoxin-A basal ganglia interspecies differences in motor behavior mouse rat interneurons hand tremor treatment electromyography kinematics essential tremor dystonic tremor tremor movement disorders Botulinum toxin upper limb biomechanics joint biomechanics diagnostic guidance clinical decision support spastic paresis electrical stimulation stroke management rehabilitation hand |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Botulinum Neurotoxins and Nervous System |
| Record Nr. | UNINA-9910557109003321 |
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Luvisetto Siro
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Biomarkers and Targets in Digestive Organs
| Cancer Biomarkers and Targets in Digestive Organs |
| Autore | Lee Nikki |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (146 p.) |
| Soggetto non controllato |
liver graft injury
HFE neurokinin chemotherapy intestinal tumors therapeutic targets biliary tract carcinoma hepatocellular carcinoma clinical trial cell adhesion molecules colorectal cancer biomarkers phenotypic mosaics gastrointestinal oncology Asian Cancer Research Group (ACRG) biomarker psychosocial support precision therapy pancreatic carcinoma precision medicine Liver transplantation predictive biomarkers CD274 cholecystokinin The Cancer Genome Atlas (TCGA) gastrin pembrolizumab immunotherapy gastrin-releasing peptide stereotactic body radiation therapy immunohistochemistry gastric carcinoma liver transplant CAM invasion assay intragraft gene expression profiles molecular profiling targeted therapy neurotensin intestinal disorder ramucirumab next-generation sequencing colorectal carcinoma tumor progenitor circulating tumor cells gastrointestinal malignancies bombesin trastuzumab somatostatin zebrafish G protein-coupled receptors |
| ISBN | 3-03921-464-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367564003321 |
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Lee Nikki
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular and Molecular Mechanisms of Nephropathic Cystinosis
| Cellular and Molecular Mechanisms of Nephropathic Cystinosis |
| Autore | Levtchenko Elena N |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (230 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
cystinosis
cysteamine bone osteoclast genotype CD34+ hematopoietic stem and progenitor cells gene therapy pre-clinical studies investigational new drug application clinical trial disulfiram mice zebrafish fertility azoospermia hypogonadism histopathology mouse model lysosomal storage disease cell and animal models infantile nephropathic cystinosis bone-muscle wasting fibroblast growth factor 23 osteoclasts sclerostin leptin fractures nephropathic cystinosis hollow fiber membrane 3-dimensional models autophagy macrophages inflammasome proximal tubular cells endocytosis apoptosis chitotriosidase interleukins galectin-3 novel therapies endolysosome epithelial cell differentiation homeostasis lysosomal storage diseases mitochondrial distress kidney proximal tubule programmed cell death central nervous system cortical atrophy arterial spin labelling cystine blood level lysosomal storage disorder history treatment strategies for cystinosis newborn screening clinical course CTNS-pathogenic variants newborn screening for cystinosis kidney progenitors cell model biomarkers cystine kidney therapeutic monitoring |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585941103321 |
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Levtchenko Elena N
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Creatine Supplementation for Health and Clinical Diseases
| Creatine Supplementation for Health and Clinical Diseases |
| Autore | Kreider Richard B |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (562 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
ergogenic aids
cellular metabolism phosphagens sarcopenia cognition diabetes creatine synthesis deficiencies concussion traumatic brain injury spinal cord injury muscle atrophy rehabilitation pregnancy immunity anti-inflammatory antioxidant anticancer creatine nutritional supplements fertility newborn development brain injury post-viral fatigue syndrome chronic fatigue syndrome GAA creatine kinase dietary supplements exercise skeletal muscle glycemic control type 2 diabetes mellitus phosphorylcreatine dietary supplement ergogenic aid youth athletes osteoporosis osteosarcopenia frailty cachexia innate immunity adaptive immunity inflammation macrophage polarization cytotoxic T cells toll-like receptors vascular pathology cardiovascular disease oxidative stress vascular health female menstrual cycle hormones exercise performance menopause mood children height BMI-for-age stature-for-age growth phosphocreatine creatine transporter supplementation treatment heart heart failure ischemia myocardial infarction anthracycline cardiac toxicity energy metabolism cell survival bioinformatics systems biology cellular allostasis dynamic biosensor pleiotropic effects of creatine (Cr) supplementation inflammatory bowel diseases (IBD) ulcerative colitis Crohn’s disease creatine kinase (CK) phosphocreatine (PCr) creatine transporter (CrT) intestinal epithelial cell protection intestinal tissue protection creatine perfusion organ transplantation Adenosine mono-phosphate (AMP) activated protein kinase (AMPK) liver kinase B1 (LKB1) mitochondrial permeability transition pore (mPTP) reactive oxygen species (ROS) glucose transporter (GLUT) T cell antitumor immunity metabolic regulator cancer immunotherapy supplements muscle damage recovery immobilization atrophy muscular dystrophy amyotrophic lateral sclerosis Parkinson’s Disease cardiopulmonary disease mitochondrial cytopathy hypertrophy athletic performance weightlifting resistance exercise training muscular power muscular adaptation muscle fatigue adipose tissue muscle strength physiological adaptation mitochondria thermogenesis MAP kinase signaling system sodium-chloride-dependent neurotransmitter symporters signal transduction intradialytic creatine supplementation hemodialysis muscle protein energy wasting clinical trial muscle weakness chronic fatigue cognitive impairment depression anemia resistance training sports nutrition strength toxicity methylation hyperhomocysteinemia neuromodulation MCDA mitochondriopathia cardiac infarction long COVID hypoxia stroke neurodegenerative diseases noncommunicable disease adenosine 5′-monopnophosphate-activated protein kinase anthracyclines creatine supplementation cardiac signaling cardiotoxicity doxorubicin soy vegetarian/vegan diet amino acids dietary ingredients performance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566476003321 |
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Kreider Richard B
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology
| Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology |
| Autore | Fioravanti Antonella |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (320 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
miR-27a-5p
acute myocardial infarction autophagy apoptosis hypoxia MicroRNA (miRNA) miR526b miR655 oxidative stress reactive oxygen species (ROS) superoxide (SO) Thioredoxin Reductase 1 (TXNRD1) breast cancer nucleic acid medicine pancreatic cancer clinical trial siRNA antisense oligonucleotide MicroRNA signal transduction therapeutic target miRNAs ROS noncoding RNA microRNA long noncoding RNA mitochondrial dysfunction nitrosative stress. exosome cross-talk systemic lupus erythematosus visfatin resistin osteoarthritis synovial fibroblasts synovitis NF-κB thyroid hormone liver cancer metabolism physiology ASH NAFLD NASH HCC HCV HBV endometriosis high-grade serous ovarian cancer endometriosis-associated ovarian cancer epithelial-to-mesenchymal transition chemoresistance antioxidants miRNA cancer diabetes beta cells microRNAs translation regulation neurodegeneration Alzheimer's disease Parkinson's disease Huntington's disease ALS reactive oxygen species redox signaling therapeutic tolerance therapeutic resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557526003321 |
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Fioravanti Antonella
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Diets, Foods and Food Components Effect on Dyslipidemia
| Diets, Foods and Food Components Effect on Dyslipidemia |
| Autore | Fogacci Federica |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
beta-glucan
fiber lipid profile cholesterol intestinal function green tea epigallocatechin gallate chitosan microspheres Eudragit metabolic diseases LCD score CHNS dyslipidemia dietary factor plant based animal based Chinese adults nutraceuticals PCSK9 SREBP HNF1α berberine metabolic syndrome plant extracts natural antioxidant polyphenols bergamot blackcurrant liver steatosis ovariectomized phytoestrogen vitamin B12 healthy Saudi Arabia serum cholesterol serum triglycerides serum low density lipoprotein serum high density lipoprotein dietary intake lifestyle black raspberry excessive choline TMAO hypercholesterolemia hepatic inflammation review CVD cardiovascular health dietary fats dietary fiber phytosterols plant-based diet dietary pattern sustainability propolis formononetin gastric ulcer rats Chrysanthemum morifolium Ramat leaves obesity lipidomics liquid chromatography tandem mass spectrometry phospholipid sphingolipid monacolins LDL-cholesterol red yeast rice clinical trial endothelial function alpha-linolenic acid flaxseed lipids omega-3 walnuts type 2 diabetes mellitus glibenclamide omega-3 fatty acids high fat diet transcription factors streptozotocin Armolipid Plus® nutraceutical supplementation blood pressure fasting plasma glucose |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557599803321 |
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Fogacci Federica
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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