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Clinical Studies, Big Data, and Artificial Intelligence in Nephrology and Transplantation
| Clinical Studies, Big Data, and Artificial Intelligence in Nephrology and Transplantation |
| Autore | Cheungpasitporn Wisit |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (374 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
tacrolimus
C/D ratio tacrolimus metabolism everolimus conversion kidney transplantation gut microbiome renal transplant recipient diarrhea immunosuppressive medication gut microbiota 16S rRNA sequencing butyrate-producing bacteria Proteobacteria torquetenovirus immunosuppression transplantation immunosuppressed host outcome renal transplantation Goodpasture syndrome anti-GBM disease epidemiology hospitalization outcomes acute kidney injury risk prediction artificial intelligence patent ductus arteriosus conservative management blood pressure eradication interferon-free regimen hepatitis C infection kidney transplant allograft steatosis lipopeliosis transplant numbers live donors public awareness Google TrendsTM machine learning big data nephrology chronic kidney disease NLR PLR RPGN predictive value hemodialysis withdrawal cellular crescent global sclerosis procurement kidney biopsy glomerulosclerosis minimally-invasive donor nephrectomy robot-assisted surgery laparoscopic surgery organ donation living kidney donation MeltDose® LCPT renal function liver transplantation metabolism erythropoietin fibroblast growth factor 23 death weekend effect in-hospital mortality comorbidity dialysis elderly klotho α-Klotho FGF-23 kidney donor Nephrology CKD-MBD CKD-Mineral and Bone Disorder deceased donor Eurotransplant Senior Program risk stratification intensive care kidney transplant recipients long-term outcomes graft failure cardiovascular mortality lifestyle inflammation vascular calcification bone mineral density dual-energy X-ray absorptiometry living donation repeated kidney transplantation graft survival prolonged ischaemic time patient survival pre-emptive transplantation metabolomics urine acute rejection allograft cystatin C hyperfiltration kidney injury molecule (KIM)-1 tubular damage genetic polymorphisms (cardiac) surgery inflammatory cytokines clinical studies chronic kidney disease (CKD) no known kidney disease (NKD) ICD-10 billing codes phenotyping electronic health record (EHR) estimated glomerular filtration rate (eGFR) machine learning (ML) generalized linear model network (GLMnet) random forest (RF) artificial neural network (ANN), clinical natural language processing (clinical NLP) discharge summaries laboratory values area under the receiver operating characteristic (AUROC) area under the precision-recall curve (AUCPR) fibrosis extracellular matrix collagen type VI living-donor kidney transplantation ethnic disparity |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557367503321 |
Cheungpasitporn Wisit
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine-Derived Products for Biomedicine
| Marine-Derived Products for Biomedicine |
| Autore | Giovine Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (214 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
Extracellular Polymeric Substances
hydrogel mesenchymal stem cells biomaterials enzyme omega 3 PUFA Trichormus variabilis Cyanobacteria mechanochemical synthesis chitosan laser stereolithography long-term stability scaffold tissue reaction chitin scaffolds biological materials demosponges Pseudoceratina arabica microalgae biodiversity bioactive compounds green extractions pharmaceutical secondary metabolites biofuels antibiofilm fucoidan motility nanoparticles Pseudomonas aeruginosa virulence factors n-3 fatty acids brain α-Chitin prodigiosin anti-tumors Serratia marcescens bioprocessing echinochrome A estradiol extracellular matrix vocal fold ovariectomy marine polymers ionic liquids tissue engineering membranes hydrogels sponges Chondrosin Chondrosia reniformis marine toxin cytotoxic protein Porifera marine microbes cancer prevention therapy in vitro in vivo clinical studies |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557103303321 |
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Giovine Marco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mediterranean Plants
| Mediterranean Plants |
| Autore | Rhizopoulou Sophia |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (152 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Helichrysum italicum
biological activity internal use clinical studies hualo Mediterranean plants seeds remote sensing MODIS enhanced vegetation index temperature precipitation rain days inter-annual variability time-series machine learning climate change Mediterranean nursery production water imbibition Mediterranean climate elongation allelochemicals specific activity phytotoxicity aridity index effective number of species Shannon entropy richness Gini–Simpson water potential stomatal conductance transpiration leaf hydraulic conductance drought Cyclamen graecum geophyte phenology seasonality neglected and underutilized plants phytogenetic resources DNA barcoding forest berries protocols nutraceutical potential genotype selection multifaceted evaluation |
| ISBN | 3-0365-4862-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639987103321 |
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Rhizopoulou Sophia
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation
| Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation |
| Autore | Gonzalez-Alvarez Maria Isabel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (238 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
bioequivalence
Biopharmaceutics Classification System in vitro dissolution test pravastatin oral absorption in silico modeling GastroPlus Phoenix WinNonlin pharmacokinetics clinical studies ibuprofen manometry gastrointestinal mechanistic modeling PBPK PBBM disintegration dissolution enteric-coated ICH quality control regional intestinal permeability permeation enhancers absorption-modifying excipients oral peptide delivery intestinal perfusion pharmaceutical development controlled release drug product biopharmaceutics classification system drug solubility drug permeability location-dependent absorption segregated flow intestinal model (SFM) traditional model (TM) route-dependent intestinal metabolism first-pass effect drug-drug interactions DDI in vitro in vivo extrapolations IVIVE zero-order absorption first-order absorption combined zero- and first-order absorption transit compartment absorption model in situ perfusion microdevices shape mucoadhesion colon absorption nutrient digestion nutrient absorption gastrointestinal hormone postprandial glycaemia energy intake region of the gut obesity type 2 diabetes Franz–PAMPA BCS drugs biomimetic membrane Franz cell passive drug transport BCS class IV drugs segmental-dependent intestinal permeability intestinal absorption oral drug delivery biopharmaceutics physiologically-based pharmacokinetic (PBPK) modeling furosemide intestinal permeability human colon carcinoma cell layer (Caco-2) hierarchical support vector regression (HSVR) drug absorption drug solubility/dissolution regional/segmental-dependent permeability and absorption |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Regional Intestinal Drug Absorption |
| Record Nr. | UNINA-9910566462603321 |
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Gonzalez-Alvarez Maria Isabel
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tuberculosis Drug Discovery and Development 2019
| Tuberculosis Drug Discovery and Development 2019 |
| Autore | Riccardi Giovanna |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (296 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
mycobacteria
tuberculosis multi-drug resistance drug discovery promiscuous targets Mycobacterium tuberculosis rifampin isoniazid mechanisms of resistance mutations granulomas caseum cell envelope dormancy delpazolid macozinone DprE1 inhibitor clinical studies discovery mode of action drug resistance toxicity target energy metabolism electron transport chain oxidative phosphorylation bedaquiline Q203 MID3 pharmacokinetics pharmacodynamics drug-drug interactions in vitro in vivo drug development tuberculosis treatment biomarkers drug combination clinical trial BCG tuberculosis vaccines TBVI EDCTP IAVI CTVD host-directed therapy anti-virulence compounds TB post-treatment sequelae surgery pulmonary rehabilitation Carlo Forlanini artificial pneumothorax structure-based drug design target-based drug design PknB PknG DNA gyrase antibiotic mycobacterium genomics transcriptomics proteomics metabolomics lipidomics target identification mechanism of action antimicrobial drug resistance (AMR) target-based screening phenotypic screening antituberculosis agents antimycobacterial anti-TB drug pipeline privileged targets lead generation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557627203321 |
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Riccardi Giovanna
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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