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Brain-Targeted Drug Delivery
| Brain-Targeted Drug Delivery |
| Autore | Sousa Flávia |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (260 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
3D cell culture systems
acetaminophen Alzheimer's disease Alzheimer's disease-relevant tau species anti-tau and anti-receptor bispecific monoclonal antibodies blood-brain barrier brain biodistribution brain cancer brain targeted therapy central composite rotatable design cerebral open flow microperfusion cerebrospinal fluid microcirculation chemoattractant claudin-5 CNS drug delivery convection-enhanced delivery CXCL CXCR delivery to brain depression diffuse midline glioma drug delivery drug delivery into the brain electrochemical biosensors GB-13 gene therapy glioblastoma glioblastoma multiforme glycol chitosan high-grade glioma hyaluronidase IL-13 IL-13Rα2 IL13.E13K-PE4E immunotherapy immunotoxin improved memory interactions between Aβ and tau intranasal delivery laser liposome macromolecules memory impairment microdialysis microparticles movement impairment n/a nanoparticle nanoparticles nanostructured lipid carrier naringenin nasal delivery system neurosurgery non-human primate nose to brain delivery opioids optogenetics Parkinson's disease phospholipid oily gel PLGA polyplexes pomegranate seed oil receptor expression seizure targeted therapy tau clearance in microglia tau clearance in neurons temporal-spatial pathological Aβ and tau distribution tight junction tolcapone transendothelium based on receptor-mediated transcytosis ultrasound |
| ISBN | 3-0365-5281-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619467203321 |
Sousa Flávia
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Tight Junction and Its Proteins : More Than Just a Barrier
| The Tight Junction and Its Proteins : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (432 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
actomyosin
adherens junction adherens junctions aging AMP-activated protein kinase (AMPK) angubindin-1 angulin anhidrosis antibiotic-associated hemorrhagic colitis antibody antidiuretic hormone apical junctional complex apoptosis aquaporin arachnoid barrier atopic dermatitis atypical aPKCζ barrier formation barrier function biliary epithelial cells blood-biliary barrier blood-brain barrier blood-cerebrospinal fluid barrier brain barriers calcium permeability Campylobacter jejuni cancer caspase CaSR celiac disease cell growth cell polarity cell-cell contact cerebral cavernous malformation chemoresistance cholangiocellular carcinoma cholestasis chronic liver disease claudin Claudin claudin 1 claudin targeting claudin-1 claudin-12 Claudin-14 claudin-2 claudin-5 Claudin-7 claudins ClC-2 CLDN14 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin co-culture cochlear implantation collecting duct curcumin cytokines disease dorsal root ganglion drinking rate drug development drug discovery endometrial cancer endothelia endothelial barrier enterocyte enteropathogenic E. coli (EPEC) environmental sensors epidermal barrier epithelia epithelial barrier epithelial barrier dysfunction epithelial fluid transport epithelial sodium channel (ENaC), collecting duct cells epithelial to mesenchymal transition epithelium EspF fibrosis gene transcription gland dysfunction glia limitans hearing loss HELIX syndrome Hepatitis C Virus hepatocellular carcinoma human hydrogen peroxide hydrostatic pressure hypermagnesemia hypertrophy hypokalemia immune cells in silico inflammation inflammatory bowel disease interleukin 13 intestinal mucosa intestine ion channel ion reabsorption ion transport ischemia junctional adhesion molecule kidney kidney stones Klebsiella oxytoca lipolysis-stimulated lipoprotein receptor (LSR) liver lung MAGUK proteins MDCK C7 cells MEKK3 membrane proteins metastasis mice migration molecular dynamics monocytes mouse colon mucosal immunology mucus mutations Mz-ChA-1 cells nephropathy nerve injury NES neuropathic pain neurovascular unit NFκB NHE2 NISCH syndrome NLS occludin organ preservation osmolality osmoregulation paracellular paracellular barrier paracellular channels and barriers paracellular permeability paracellular sodium transport paracellular transport paracellular water transport pathogens PDZ domain permeability phosphatidylcholine phosphorylation polarity proliferation protein domain protein interactions protein structure proximal tubule quercetin reconstructed human epidermis repair retinal pigment epithelium retinopathy Rho RhoA ROCK sensor single molecule localization microscopy skin sorting nexin 9 (SNX9) STAT3 stem cell stimulated emission depletion structured illumination microscopy super-resolution microscopy thick ascending limb tight epithelium tight junction tight junction assembly tight junctions tight junctions (TJ) tissue barrier TNF transepithelial electrical resistance (TER) transplantation tricellular tight junction tricellular tight junctions tricellulin tumor tumor suppressor UBE2Z ubiquitin vestibular function viral entry WNK4 ZO-1 ZO-2 zonula occludens |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910557404603321 |
|
Fromm Michael
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier
| The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (412 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
actomyosin
adherens junction adherens junctions aging AMP-activated protein kinase (AMPK) angubindin-1 angulin anhidrosis antibiotic-associated hemorrhagic colitis antibody antidiuretic hormone apical junctional complex apoptosis aquaporin arachnoid barrier atopic dermatitis atypical aPKCζ barrier formation barrier function biliary epithelial cells blood-biliary barrier blood-brain barrier blood-cerebrospinal fluid barrier brain barriers calcium permeability Campylobacter jejuni cancer caspase CaSR celiac disease cell growth cell polarity cell-cell contact cerebral cavernous malformation chemoresistance cholangiocellular carcinoma cholestasis chronic liver disease claudin Claudin claudin 1 claudin targeting claudin-1 claudin-12 Claudin-14 claudin-2 claudin-5 Claudin-7 claudins ClC-2 CLDN14 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin co-culture cochlear implantation collecting duct curcumin cytokines disease dorsal root ganglion drinking rate drug development drug discovery endometrial cancer endothelia endothelial barrier enterocyte enteropathogenic E. coli (EPEC) environmental sensors epidermal barrier epithelia epithelial barrier epithelial barrier dysfunction epithelial fluid transport epithelial sodium channel (ENaC), collecting duct cells epithelial to mesenchymal transition epithelium EspF fibrosis gene transcription gland dysfunction glia limitans hearing loss HELIX syndrome Hepatitis C Virus hepatocellular carcinoma human hydrogen peroxide hydrostatic pressure hypermagnesemia hypertrophy hypokalemia immune cells in silico inflammation inflammatory bowel disease interleukin 13 intestinal mucosa intestine ion channel ion reabsorption ion transport ischemia junctional adhesion molecule kidney kidney stones Klebsiella oxytoca lipolysis-stimulated lipoprotein receptor (LSR) liver lung MAGUK proteins MDCK C7 cells MEKK3 membrane proteins metastasis mice migration molecular dynamics monocytes mouse colon mucosal immunology mucus mutations Mz-ChA-1 cells nephropathy nerve injury NES neuropathic pain neurovascular unit NFκB NHE2 NISCH syndrome NLS occludin organ preservation osmolality osmoregulation paracellular paracellular barrier paracellular channels and barriers paracellular permeability paracellular sodium transport paracellular transport paracellular water transport pathogens PDZ domain permeability phosphatidylcholine phosphorylation polarity proliferation protein domain protein interactions protein structure proximal tubule quercetin reconstructed human epidermis repair retinal pigment epithelium retinopathy Rho RhoA ROCK sensor single molecule localization microscopy skin sorting nexin 9 (SNX9) STAT3 stem cell stimulated emission depletion structured illumination microscopy super-resolution microscopy thick ascending limb tight epithelium tight junction tight junction assembly tight junctions tight junctions (TJ) tissue barrier TNF transepithelial electrical resistance (TER) transplantation tricellular tight junction tricellular tight junctions tricellulin tumor tumor suppressor UBE2Z ubiquitin vestibular function viral entry WNK4 ZO-1 ZO-2 zonula occludens |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910674057303321 |
|
Fromm Michael
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||