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The Tight Junction and Its Proteins : More Than Just a Barrier
| The Tight Junction and Its Proteins : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (432 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
tissue barrier
tight junction claudins tricellulin tight junctions organ preservation intestine transplantation ischemia intestinal mucosa lung epithelia interleukin 13 UBE2Z ubiquitin osmolality hydrostatic pressure cancer sensor tricellular tight junctions endometrial cancer epithelial barrier dysfunction Claudin-7 permeability WNK4 epithelial sodium channel (ENaC), collecting duct cells claudin-1 hydrogen peroxide phosphorylation claudin angulin drug development angubindin-1 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin antibody Mz-ChA-1 cells biliary epithelial cells phosphatidylcholine mucus paracellular transport atopic dermatitis cytokines STAT3 ZO-2 cholestasis gene transcription hypertrophy tumor suppressor NLS NES CaSR RhoA barrier function paracellular permeability antidiuretic hormone Claudin-14 CLDN14 hearing loss vestibular function cochlear implantation Hepatitis C Virus viral entry epidermal barrier reconstructed human epidermis claudin targeting Campylobacter jejuni curcumin apoptosis co-culture mouse colon TNF NFκB lipolysis-stimulated lipoprotein receptor (LSR) epithelial barrier cell–cell contact caspase kidney stones ion reabsorption quercetin brain barriers blood-brain barrier neurovascular unit blood-cerebrospinal fluid barrier arachnoid barrier glia limitans adherens junctions paracellular sodium transport thick ascending limb nephropathy HELIX syndrome hypokalemia hypermagnesemia anhidrosis gland dysfunction aging blood–brain barrier mutations kidney liver skin human mice disease in silico drug discovery membrane proteins protein interactions molecular dynamics antibiotic-associated hemorrhagic colitis Klebsiella oxytoca tight junction assembly monocytes celiac disease claudin-2 epithelium inflammation fibrosis proliferation migration tricellular tight junction paracellular water transport tight epithelium MDCK C7 cells cell growth endothelia adherens junction apical junctional complex AMP-activated protein kinase (AMPK) paracellular barrier protein structure protein domain occludin junctional adhesion molecule zonula occludens MAGUK proteins PDZ domain stem cell chemoresistance retinal pigment epithelium retinopathy barrier formation collecting duct claudin-5 neuropathic pain nerve injury dorsal root ganglion enteropathogenic E. coli (EPEC) tight junctions (TJ) polarity atypical aPKCζ transepithelial electrical resistance (TER) sorting nexin 9 (SNX9) EspF claudin 1 tumor metastasis epithelial to mesenchymal transition cerebral cavernous malformation endothelial barrier Rho ROCK MEKK3 ion transport ion channel super-resolution microscopy structured illumination microscopy stimulated emission depletion single molecule localization microscopy Claudin blood-biliary barrier chronic liver disease hepatocellular carcinoma cholangiocellular carcinoma NISCH syndrome repair NHE2 ClC-2 inflammatory bowel disease mucosal immunology ZO-1 actomyosin aquaporin drinking rate epithelial fluid transport enterocyte osmoregulation paracellular proximal tubule calcium permeability claudin-12 paracellular channels and barriers cell polarity pathogens immune cells environmental sensors |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910557404603321 |
Fromm Michael
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier
| The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (412 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
tissue barrier
tight junction claudins tricellulin tight junctions organ preservation intestine transplantation ischemia intestinal mucosa lung epithelia interleukin 13 UBE2Z ubiquitin osmolality hydrostatic pressure cancer sensor tricellular tight junctions endometrial cancer epithelial barrier dysfunction Claudin-7 permeability WNK4 epithelial sodium channel (ENaC), collecting duct cells claudin-1 hydrogen peroxide phosphorylation claudin angulin drug development angubindin-1 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin antibody Mz-ChA-1 cells biliary epithelial cells phosphatidylcholine mucus paracellular transport atopic dermatitis cytokines STAT3 ZO-2 cholestasis gene transcription hypertrophy tumor suppressor NLS NES CaSR RhoA barrier function paracellular permeability antidiuretic hormone Claudin-14 CLDN14 hearing loss vestibular function cochlear implantation Hepatitis C Virus viral entry epidermal barrier reconstructed human epidermis claudin targeting Campylobacter jejuni curcumin apoptosis co-culture mouse colon TNF NFκB lipolysis-stimulated lipoprotein receptor (LSR) epithelial barrier cell–cell contact caspase kidney stones ion reabsorption quercetin brain barriers blood-brain barrier neurovascular unit blood-cerebrospinal fluid barrier arachnoid barrier glia limitans adherens junctions paracellular sodium transport thick ascending limb nephropathy HELIX syndrome hypokalemia hypermagnesemia anhidrosis gland dysfunction aging blood–brain barrier mutations kidney liver skin human mice disease in silico drug discovery membrane proteins protein interactions molecular dynamics antibiotic-associated hemorrhagic colitis Klebsiella oxytoca tight junction assembly monocytes celiac disease claudin-2 epithelium inflammation fibrosis proliferation migration tricellular tight junction paracellular water transport tight epithelium MDCK C7 cells cell growth endothelia adherens junction apical junctional complex AMP-activated protein kinase (AMPK) paracellular barrier protein structure protein domain occludin junctional adhesion molecule zonula occludens MAGUK proteins PDZ domain stem cell chemoresistance retinal pigment epithelium retinopathy barrier formation collecting duct claudin-5 neuropathic pain nerve injury dorsal root ganglion enteropathogenic E. coli (EPEC) tight junctions (TJ) polarity atypical aPKCζ transepithelial electrical resistance (TER) sorting nexin 9 (SNX9) EspF claudin 1 tumor metastasis epithelial to mesenchymal transition cerebral cavernous malformation endothelial barrier Rho ROCK MEKK3 ion transport ion channel super-resolution microscopy structured illumination microscopy stimulated emission depletion single molecule localization microscopy Claudin blood-biliary barrier chronic liver disease hepatocellular carcinoma cholangiocellular carcinoma NISCH syndrome repair NHE2 ClC-2 inflammatory bowel disease mucosal immunology ZO-1 actomyosin aquaporin drinking rate epithelial fluid transport enterocyte osmoregulation paracellular proximal tubule calcium permeability claudin-12 paracellular channels and barriers cell polarity pathogens immune cells environmental sensors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910674057303321 |
|
Fromm Michael
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Transmucosal Absorption Enhancers in the Drug Delivery Field
| Transmucosal Absorption Enhancers in the Drug Delivery Field |
| Autore | Maher Sam |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (406 p.) |
| Soggetto non controllato |
chitosan
intestinal epithelial cells ocular delivery amphiphilic polymers cornea tight junction modulator cyclodextrin permeability gemini surfactant transferrin compound 48/80 epithelial permeability cervicovaginal tumors nanoparticles confocal laser scanning microscopy safety formulation salcaprozate sodium intestinal absorption FITC-dextran curcumin block copolymers nasal vaccination whole leaf brush border ocular drug delivery vaccine adjuvant nanoparticle nasal delivery efflux permeation enhancers absorption enhancers nose to brain delivery small intestine epithelium CNS disorders absorption modifying excipients insulin absorption enhancer gel intestinal delivery thermogel system Caco-2 biocompatibility studies absorption enhancement man PN159 poorly absorbed drug tryptophan tight junction oral macromolecule delivery penetration enhancer intestinal permeation enhancers nanocrystals simvastatin nanomedicine enterocyte N-dodecyl-?-D-maltoside (DDM) cell-penetrating peptide quaternization KLAL nasal nasal permeability transmucosal drug delivery Caco-2 cells mast cell activator penetration enhancers drug delivery nose-to-brain bioenhancer polymeric micelles mucoadhesion cell-penetrating peptide (CPP) simulated intestinal fluid vaginal delivery nasal formulation pharmacokinetic interaction sodium caprate clinical trial transmucosal permeation drug absorption enhancer sugar-based surfactants nanocapsules imatinib teriparatide osteoporosis hydrophobization F-actin combined microsphere transepithelial electrical resistance oral delivery ocular conditions metabolism antimicrobial peptide permeation enhancer drug administration antiepileptic drug amino acid in vivo studies sodium cholate (NaC) epithelial transport preclinical nose to brain transport pharmacokinetics chitosan derivatives ophthalmology tight junctions sheep cationic functionalization GLP-1 pulmonary and liposome cytochrome P450 claudin P-glycoprotein in situ hydrogel mucoadhesiveness PTH 1-34 Aloe vera oral peptides |
| ISBN | 3-03921-849-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910372785603321 |
|
Maher Sam
|
||
| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||