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Advanced Polymers for Biomedical Applications
| Advanced Polymers for Biomedical Applications |
| Autore | García-Fernández Luis |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (432 p.) |
| Soggetto topico |
Technology: general issues
Biotechnology |
| Soggetto non controllato |
biocomposite
chitosan chlorhexidine coating hernia mesh infection nanoparticles PLGA polypropylene rifampicin 3D-bioprinting static mixer reactive hydrogel hyaluronic acid modified chitosan curcumin microwave interpenetrated polymer network semi-IPN methacrylated hyaluronic acid glycerylphytate mesenchymal stem cell bioadhesion biomaterials biomedical application healthcare system management innovation polymer based bioadhesive polymers magnetite nanoparticles Tween 80 synthesis nanotoxicology genotoxicity hemotoxicity soy protein film semiconductor biomaterial additive manufacturing sterilization medical devices bioabsorbable polymer biopolymer hydrogel microparticles dye release drug delivery system dual-responsiveness dendritic polyglycerol sulfates biofabrication microfluidics electrospinning 3D printing electrospraying natural polymers cell encapsulation polymeric prodrug dual-sensitive combination chemotherapy drug conjugation dextran hydrogels carboxymethyl cellulose succinoglycan metal coordination drug delivery swelling properties extracellular matrix external stimuli tissue maturation gelatin sodium carboxymethyl cellulose scaffold A549 cells freeze drying silicone rubber biomechanical hyper-elastic constitutive model FEA pH-sensitive hydrogel poly(acrylic acid) quartz crystal microbalance (QCM) ellipsometric measurement antibacterial activity Ganoderma lucidum polysaccharides cisplatin synergistic effect anti-lung cancer nanocellulose fiber low methoxyl pectin sodium alginate clindamycin pancreatic cancer gemcitabine controlled release non-woven sheet chemotherapy antitumor efficacy poly(L-lactic acid) antimicrobials agents amphiphilic block copolymer quaternized polymer hemolysis micelle black phosphorus polyetheretherketone lubrication properties antibacterial properties sensorineural hearing loss cochlear implants self-bending electrode arrays silicone rubber–hydrogel composites actuators swelling behavior curvature biocompatibility nanofibrous dura mater antifibrosis neuroprotection tetramethylpyrazine |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580212803321 |
García-Fernández Luis
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Drugs
| Anticancer Drugs |
| Autore | O’Boyle Niamh M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (214 p.) |
| Soggetto non controllato |
graphene oxide
indole androgens cyclooxygenase-2 cyclooxygenase-1 heteropolysaccharide drug conjugation drug delivery ellipticine chemical linker oesophageal cancer antiproliferative activity topoisomerase II ?-lactam DSD antibody topoisomerase inhibitors magnetic targeting cisplatin resistance steroidogenesis [18F]FDG PET/CT heterocyclic chemistry dehydroepiandrosterone antimitotic 3-vinylazetidin-2-ones glioblastoma and cancer therapy intestinal mucositis Combretastatin A-4 metabolism anti-cancer drugs maghemite COX-1 inhibitor anticancer CYP17A1 conjugate and hybrid drugs inflammation snticancer drugs P450c17 tumorigenesis cisplatin biomarker profiling cancer drug design tubulin cytochrome P450 5-fluorouracil prostate cancer abiraterone NCI screen radiation cancer immunotherapy microtubule targeted drugs cancer treatment resistance |
| ISBN | 3-03921-587-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367753903321 |
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O’Boyle Niamh M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumor and Anti-HIV Agents from Natural Products
| Antitumor and Anti-HIV Agents from Natural Products |
| Autore | Nakagawa-Goto Kyoko |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (338 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
natural phaeosphaeride A
antitumor activity human tumor cell lines HEF cell line acute toxicity aspidosperma-type monoterpenoid indole alkaloids antiproliferative activity tubulin inhibitor Bousigonia mekongensis ursolic acid DOTA triterpenoids cytotoxicity diterpenoid alkaloids human tumor cells lipojesaconitine delcosine delpheline kobusine pseudokobusine BRAF inhibitor Mentha aquatica var. Kenting Water Mint essential oil chemoprevention two-stage skin carcinogenesis melanoma curcumin analog apoptosis oxidative stress drug–drug interaction tamoxifen taxol cisplatin Artemisia absinthium L. antioxidants total phenolic content melanoma and breast cancer cell line HaCaT cells inflammation breast cancer cell cycle flavonoids reactive oxygen species tumor suppression antiretroviral agents anti-HIV marine metabolites natural products drug development Ivalin Carpesium divaricatum hepatocellular carcinoma mitochondria-mediated apoptosis NF-κB Hernandia nymphaeifolia butanolides lignan glycosides coumarins antiangiogenic cancer natural agents chemistry medicine cancer stem cell cervical cancer pterostilbene resveratrol caffeic acid cancer multidrug resistance P-glycoprotein phenolic acid oxypeucedanin Angelica dahurica antiproliferation G2/M phase cell cycle arrest p53 SK-Hep-1 hepatoma cells allyl isothiocyanate benzyl isothiocyanate sulforaphane phenethyl isothiocyanate bladder cancer quercetin oral squamous cell carcinoma cells metastasis cell cycle arrest epithelial-to-mesenchymal transition matrix metalloproteinase transforming growth factor-β1 β-lapachone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557504803321 |
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Nakagawa-Goto Kyoko
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bayesian Design in Clinical Trials
| Bayesian Design in Clinical Trials |
| Autore | Berchialla Paola |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (190 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
dose-escalation
combination study modelling assumption interaction adaptive designs adaptive randomization Bayesian designs clinical trials predictive power target allocation Bayesian inference highest posterior density intervals normal approximation predictive analysis sample size determination bayesian meta-analysis clustering binary data priors frequentist validation Bayesian rare disease prior distribution meta-analysis sample size bridging studies distribution distance oncology phase I dose-finding dose–response bayesian inference prior elicitation latent dirichlet allocation clinical trial power-prior poor accrual Bayesian trial cisplatin doxorubicin oxaliplatin dose escalation PIPAC peritoneal carcinomatosis randomized controlled trial causal inference doubly robust estimation propensity score Bayesian monitoring futility rules interim analysis posterior and predictive probabilities stopping boundaries Bayesian trial design early phase dose finding treatment combinations optimal dose combination |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557608103321 |
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Berchialla Paola
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Benefits of Resveratrol Supplementation
| Benefits of Resveratrol Supplementation |
| Autore | Fernandez-Quintela Alfredo |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto non controllato |
polyphenols
?-viniferin leptin resistance p53 kidney energy restriction grape powder extract cytokines phosphorylation obesity energy metabolism metabolic pathways endothelial function polyol pathway antioxidant caloric restriction rat adipose tissue microparticles pathways angiotensin converting enzyme 2 resistance esRAGE interleukins metabolic syndrome dissolution rate thermogenesis streptozotocin bioavailability solubility metabolism renin-angiotensin system microbiota Sirt-1 magnesium dihydroxide hypertrophy metabolic diseases physiological adaption red wine extract lens distribution MTA1 sirtuin inflammation cardiac function rats cisplatin resveratrol mitochondria breast cancer ischemia-reperfusion cardiovascular metabolites gut microbiota prostate cancer performance type 2 diabetes cafeteria diet high-fat high-sucrose diet resistance exercise aging diabetes oxidative stress |
| ISBN | 3-03921-276-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346854603321 |
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Fernandez-Quintela Alfredo
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular Mechanisms of Ototoxicity
| Cellular Mechanisms of Ototoxicity |
| Autore | Carlos Esquivel |
| Pubbl/distr/stampa | Frontiers Media SA, 2018 |
| Descrizione fisica | 1 electronic resource (292 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
blood-labyrinth barrier
neurotoxicity otoprotection aminoglycosides ototoxic synergy sensory disorders cisplatin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346743503321 |
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Carlos Esquivel
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| Frontiers Media SA, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug delivery technology development in Canada / / special issue editors, Kishor M. Wasan, Ildiko Badea
| Drug delivery technology development in Canada / / special issue editors, Kishor M. Wasan, Ildiko Badea |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (352 p.) |
| Disciplina | 615.1/900971 |
| Soggetto topico | Drug Delivery Systems - Canada |
| Soggetto non controllato |
encapsulation
biodistribution pharmaceutics targeted therapies gambogic acid GE11 peptide formulation and dosage form development transient modulation ROESY NMR spectroscopy bioaccessibility polymeric micelle pharmacological Inhibitors of HIF-1 and STAT3 nanoparticles Vitamin D drug discovery EGFR-targeted therapy translational research clinical trials doxorubicin dissolution drug development permeation enhancers Canada plant primary central nervous system lymphomas photostabilizers head and neck squamous cell carcinoma mouse models drug delivery systems melphalan hypoxia-induced chemoresistance skin virus circadian clock child friendly formulation adenanthin co-delivery canola oil deodorizer distillate Metaplex innovation controlled drug delivery nifedipine radiolabeling amphotericin B biological barriers blood-brain barrier (BBB) biologicals lipid nanoparticles oral formulation phytosterols medical devices chronotherapy oral cationic gemini surfactant route of administration drug delivery intra-arterial chemotherapy developing world sustained delivery water miscible solvents combination therapy antibodies throughput magnetic fields liposomes medulloblastoma drug-resistant melanoma rosmarinic acid topical formulation TNO gastrointestinal model gastrointestinal simulator malignant gliomas transdermal drug delivery oral delivery precision medicine 3D spheroid flavonoids staurosporine DOX-Vit D loading gradients bacteriophage phospholipid complex triggered drug release HIF-1 phage display pharmacokinetics emulsion quercetin cisplatin parasitic infections remote loading HAV6 cadherin peptide blood-brain barrier inclusion complex tocopherols STAT3 ultrasound liposome fungal infections magnetic resonance imaging (MRI) MG63 model orange juice radiation cancer mefloquine small molecules |
| ISBN | 3-03928-005-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367736503321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Metabolism/Transport and Pharmacokinetics
| Drug Metabolism/Transport and Pharmacokinetics |
| Autore | Song Im-Sook |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (232 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
tofacitinib
dose-dependent pharmacokinetics hepatic and intestinal first-pass effect rats catalposide in vitro human metabolism UDP-glucuronosyltransferase sulfotransferase carboxylesterase celecoxib drug–drug interaction fluorescence HPLC metabolism repaglinide HSG4112 anti-obesity agent stereoselectivity pharmacokinetics compound K protopanaxadiol (PPD) biliary excretion intestinal metabolism Carthamus tinctorius extract notoginseng total saponins comparative pharmacokinetic study large volume direct injection compatibility mechanism mertansine human hepatocytes cytochrome P450 UDP-glucuronosyltransferases sodium-glucose cotransporter 2 (SGLT2) inhibitors DWP16001 kidney distribution inhibition mode diabetes transporter-enzyme interplay influx transporter efflux transporter physiologically based pharmacokinetic model cytochrome P450 enzymes tiropramide healthy Korean subjects modeling population pharmacokinetic quercetin breast cancer resistance protein inhibitor prazosin sulfasalazine kinetic analysis food–drug interactions Caco-2 EpiIntestinal first-pass P-gp BCRP drug transporter CYP3A4 oral availability automatization drug absorption drug dosing head-and-neck cancer real-time measurements taxanes tissue engineering UHPLC-MS/MS metformin verapamil drug interaction organic cation transporter 2 renal excretion acute renal failure gentamicin cisplatin hepatic CYP3A1(23) creatinine clearance renal clearance nonrenal clearance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607703321 |
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Song Im-Sook
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Free Radical Research in Cancer
| Free Radical Research in Cancer |
| Autore | Čipak Gašparović Ana |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (192 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
NQO1
NQO1*2 polymorphism quinone breast cancer menadione lapachone doxorubicin ascorbate oxidative stress reactive oxygen species sperm cancer chemotherapy antioxidant therapy antioxidant proteins chemoresistance oxaliplatin 5-Fluorouracil myelodysplastic syndromes carbonylation deferasirox ovary calcium channel Trolox granulosa cell tumor cell death mitochondria photodynamic therapy singlet oxygen nitric oxide light combination therapy antioxidants bleomycin cancer treatment chemotherapy-induced toxicity cisplatin free radicals methotrexate ozone therapy lung cancer cancer metabolism reactive oxygen species (ROS) therapy resistance new therapeutic strategies breast cancer stem cells 4-hydroxy-2-nonenal extracellular matrix NRF2 bardoxolone methyl prostate cancer castration-resistant prostate cancer androgen receptor (AR), AR-V7 anti-androgen enzalutamide androgen deprivation therapy cancer antioxidant triphala ayurveda chemoprevention and chemotherapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557152603321 |
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Čipak Gašparović Ana
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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From a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential
| From a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential |
| Autore | Ribaudo Giovanni |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (234 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
SARS-CoV-2
benzoic acid derivatives gallic acid molecular docking reactivity parameters selenoxide elimination one-pot imine-enamine reaction mechanism DFT calculations selenium anti-inflammatory drugs QSAR pain management cyclooxygenase multitarget drug cannabinoid neuropathic pain clopidogrel NMR study oxone peroxymonosulfate sodium halide thienopyridine drug discovery precision medicine pharmacodynamics pharmacokinetics coronavirus SARS-CoV-2 COVID-19 3-chymotrypsin-like protease pyrimidonic pharmaceuticals molecular dynamics simulations binding free energy β-carrageenan antioxidant activity Box-Behken extraction Eucheuma gelatinae physic-chemistry rheology quercetin quercetin 3-O-glucuronide cisplatin nephrotoxicity cytoprotection lithium therapy neurocytology toxicology neuroprotection chemoinformatics big data methadone hydrochloride pharmaceutical solutions drug compounding high performance liquid chromatography stability study microbiology fucoidan alginate L-selectin E-selectin MCP-1 ICAM-1 THP-1 macrophage monocyte migration protein binding breast milk M/P ratio statistical modeling molecular descriptors chromatographic descriptors affinity chromatography anti-ACE anti-DPP-IV gastrointestinal digestion in silico molecular dynamics paramyosin seafood target fishing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | From a Molecule to a Drug |
| Record Nr. | UNINA-9910585940503321 |
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Ribaudo Giovanni
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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