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Advance in the Treatment of Pediatric Leukemia
| Advance in the Treatment of Pediatric Leukemia |
| Autore | Handgretinger Rupert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (300 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
5-azacitidine
ABCC4 acute lymphoblastic leukemia acute myeloid leukemia acute pancreatitis ADC advances ALL allogeneic stem cell transplantation alternative donors AML antibody antibody-drug conjugate B-ALL BCL11B BCP-ALL bispecific T-cell engager (BiTE) CD19 CFTR childhood acute lymphoblastic leukemia children chronic myeloid leukemia CML conditioning regimen COVID-19 diagnosis DUX4 evolution of CAR T cells Fc-engineering FDA-approved CAR products future directions of CAR T cell therapy genome hematopoietic stem cell transplantation IKZF1 immunizations immunotherapy juvenile myelomonocytic leukemia L-asparaginase leukemia limitations and complications of CAR T cell therapy low-risk ALL lymphoblastic leukemia minimal residual disease myelodysplastic/myeloproliferative disorders n/a NOTCH1 NUTM1 other extramedullary relapse PAX5 pediatric pediatric leukemia Ph-like polymorphism prognosis RAS signaling risk-stratified treatment SNV T-ALL targeted therapy TcR versus CAR TRAIL transcriptome treatment treatment related toxicity tyrosine kinase inhibitor xenograft ZNF384 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576878903321 |
Handgretinger Rupert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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DNA Damage, Oxidative Stress and Related Metabolic By-Products in Cancer and Environmental Studies
| DNA Damage, Oxidative Stress and Related Metabolic By-Products in Cancer and Environmental Studies |
| Autore | Peluso Marco E. M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (188 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
8-oxoguanine
abasic sites apoptosis autoimmunity base excision repair (BER) base excision repair (BER)glycosylases benzo[a]pyrene BPDE-DNA adduct cancer carcinogens chromatin organization chronic myeloid leukemia colorectal cancer comet assay detoxification Diamond-Blackfan anemia DNA damage DNA damage response DNA damage response and repair network DNA double-strand breaks DNA repair drug resistance environment pollution erythrocyte lifespan general anesthesia genetic instability hormesis immune response inflammatory cytokines M1dG metabolic adaptation metal biocontamination metallome metals n/a nasal epithelia neuraxial anesthesia Nrf2 nucleotide excision repair (NER) oxidative DNA damage oxidative stress PXR reactive oxygen species reactive oxygen species (ROS) rheumatoid arthritis silymarin systemic lupus erythematosus systemic sclerosis thyroid thyroid cancer VOCs volcano wood dust |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557898203321 |
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Peluso Marco E. M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dynamical Models of Biology and Medicine / Meng Fan, Yang Kuang, Wanbiao Ma, Shengqiang Liu
| Dynamical Models of Biology and Medicine / Meng Fan, Yang Kuang, Wanbiao Ma, Shengqiang Liu |
| Autore | Fan Meng |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (294 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
predator-prey model
uncertainty quantification identification of DNA-binding proteins chemostat numerical characterization differential equations uniform persistence spotting 2-combination wildfire chronic myeloid leukemia combination therapy liquid-solid-porous media seepage coupling dynamic model obesity epidermis articular cartilage androgen deprivation therapy quorum sensing mechano-electrochemical model bifurcations bacterial competition global stability cartilage degeneration flocculation dynamical system transport equations bootstrapping stationary distribution algae growth models hemodynamic model delay Raphidocelis subcapitata cartilage loading Daphnia magna cell-based vector switched harvest hepatitis B rich dynamics spotting distribution asymptotic theory tyrosine kinase inhibitors phylogenetic analysis immune response microcirculation load graphical representation intraguild predation numerical simulation bacterial inflammation data fitting immunomodulatory therapies drug therapy delay differential equations (DDE) global asymptotic stability model comparison tests optimal control generalized pseudo amino acid composition random perturbations limit cycle prostate cancer mathematical model mathematical modeling persistence equilibrium points |
| ISBN |
9783039212187
3039212184 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367757303321 |
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Fan Meng
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Natural Products as Anticancer Agents
| Marine Natural Products as Anticancer Agents |
| Autore | Alves Celso |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (150 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
alga
anti-cancer antitumor aplysinopsin analogs apoptosis astaxanthin BH3 mimetics bioactive compounds biscembranoid-type metabolites BT20 cancer stem cells cancer therapy chronic myeloid leukemia colony formation cytotoxicity Ehlich's tumor environment epigenetic signaling epigenome epithelial-mesenchymal transition flaccidoxide-13-acetate gram-scale hepatocellular carcinoma hydroxyphenylacetic acid indole alkaloids inflammation inflammatory factor production invasion LPS-stimulated murine macrophage marine source marine species marine-derived fungus meroterpenoids migration mutp53 n/a nannocystin Nanog natural product Oct4 P. purpurogenum Penicillium chrysogenum polyketide pontin proliferation prostate cancer Sarcophyton digitatum secondary metabolites siRNA STAT3 T47D total synthesis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557595603321 |
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Alves Celso
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Paediatric Formulation: Design and Development
| Paediatric Formulation: Design and Development |
| Autore | Denora Nunzio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (205 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
acceptable
administration age-related anakinra autoinflammatory disease bioavailability biopharmaceutics canakinumab child children chronic myeloid leukemia confocal microscopy cyclodextrin inclusion complex dasatinib design design of experiments development device dosage form drug delivery Duchenne muscular dystrophy edible films excipient flavor profile formulation formulation development grinding imatinib inhaled innovative biotechnologies Interleukin-1 intra nasal Kawasaki disease liquid formulation medication error modified release neglected tropical diseases neonates NICU nilotinb Norvir® oral Orodispersible formulation paediatric paediatric age paediatric dosage forms paediatric formulation development palatability assessment palatable parenteral pediatric pediatric age pediatric drug delivery pediatrics penetration personalized medicine phase solubility studies polymorph ponatinib poorly soluble compound poorly water soluble drug product development pyrazinamide retinoblastoma ritonavir solubility enhancement spray congealing systemic juvenile idiopathic arthritis taste-masking topical topotecan tuberculosis tumorspheres tyrosine kinase inhibitors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Paediatric Formulation |
| Record Nr. | UNINA-9910557304003321 |
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Denora Nunzio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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