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Advance in the Treatment of Pediatric Leukemia
| Advance in the Treatment of Pediatric Leukemia |
| Autore | Handgretinger Rupert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
acute lymphoblastic leukemia
pediatric advances diagnosis treatment immunotherapy bispecific T-cell engager (BiTE) BCP-ALL leukemia TRAIL antibody Fc-engineering xenograft CD19 juvenile myelomonocytic leukemia RAS signaling hematopoietic stem cell transplantation 5-azacitidine myelodysplastic/myeloproliferative disorders targeted therapy ADC antibody-drug conjugate pediatric leukemia ALL AML allogeneic stem cell transplantation acute myeloid leukemia minimal residual disease conditioning regimen alternative donors B-ALL DUX4 IKZF1 PAX5 Ph-like ZNF384 NUTM1 T-ALL NOTCH1 BCL11B transcriptome genome chronic myeloid leukemia CML tyrosine kinase inhibitor immunizations COVID-19 childhood acute lymphoblastic leukemia low-risk ALL risk-stratified treatment treatment related toxicity L-asparaginase acute pancreatitis polymorphism SNV ABCC4 CFTR other extramedullary relapse lymphoblastic leukemia children prognosis evolution of CAR T cells FDA-approved CAR products TcR versus CAR limitations and complications of CAR T cell therapy future directions of CAR T cell therapy |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576878903321 |
Handgretinger Rupert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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DNA Damage, Oxidative Stress and Related Metabolic By-Products in Cancer and Environmental Studies
| DNA Damage, Oxidative Stress and Related Metabolic By-Products in Cancer and Environmental Studies |
| Autore | Peluso Marco E. M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (188 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
wood dust
nasal epithelia VOCs M1dG reactive oxygen species (ROS) nucleotide excision repair (NER) base excision repair (BER) oxidative DNA damage DNA damage response and repair network immune response autoimmunity systemic lupus erythematosus systemic sclerosis rheumatoid arthritis oxidative stress abasic sites chromatin organization apoptosis DNA damage general anesthesia neuraxial anesthesia comet assay chronic myeloid leukemia genetic instability DNA double-strand breaks DNA damage response benzo[a]pyrene BPDE-DNA adduct silymarin detoxification Nrf2 PXR DNA repair base excision repair (BER)glycosylases colorectal cancer reactive oxygen species metabolic adaptation drug resistance cancer thyroid thyroid cancer volcano metals metallome carcinogens hormesis environment pollution metal biocontamination Diamond-Blackfan anemia 8-oxoguanine inflammatory cytokines erythrocyte lifespan |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557898203321 |
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Peluso Marco E. M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dynamical Models of Biology and Medicine
| Dynamical Models of Biology and Medicine |
| Autore | Kuang Yang |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (294 p.) |
| Soggetto non controllato |
predator-prey model
uncertainty quantification identification of DNA-binding proteins chemostat numerical characterization differential equations uniform persistence spotting 2-combination wildfire chronic myeloid leukemia combination therapy liquid-solid-porous media seepage coupling dynamic model obesity epidermis articular cartilage androgen deprivation therapy quorum sensing mechano-electrochemical model bifurcations bacterial competition global stability cartilage degeneration flocculation dynamical system transport equations bootstrapping stationary distribution algae growth models hemodynamic model delay Raphidocelis subcapitata cartilage loading Daphnia magna cell-based vector switched harvest hepatitis B rich dynamics spotting distribution asymptotic theory tyrosine kinase inhibitors phylogenetic analysis immune response microcirculation load graphical representation intraguild predation numerical simulation bacterial inflammation data fitting immunomodulatory therapies drug therapy delay differential equations (DDE) global asymptotic stability model comparison tests optimal control generalized pseudo amino acid composition random perturbations limit cycle prostate cancer mathematical model mathematical modeling persistence equilibrium points |
| ISBN | 3-03921-218-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367757303321 |
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Kuang Yang
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Natural Products as Anticancer Agents
| Marine Natural Products as Anticancer Agents |
| Autore | Alves Celso |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (150 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
alga
marine-derived fungus Penicillium chrysogenum polyketide hydroxyphenylacetic acid cytotoxicity flaccidoxide-13-acetate hepatocellular carcinoma invasion migration epithelial-mesenchymal transition prostate cancer astaxanthin STAT3 proliferation colony formation apoptosis Sarcophyton digitatum biscembranoid-type metabolites inflammatory factor production LPS-stimulated murine macrophage Ehlich's tumor P. purpurogenum antitumor meroterpenoids inflammation T47D BT20 pontin mutp53 cancer stem cells Oct4 Nanog siRNA secondary metabolites epigenome epigenetic signaling bioactive compounds cancer therapy marine species environment total synthesis natural product nannocystin anti-cancer gram-scale aplysinopsin analogs indole alkaloids marine source chronic myeloid leukemia BH3 mimetics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557595603321 |
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Alves Celso
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Paediatric Formulation: Design and Development
| Paediatric Formulation: Design and Development |
| Autore | Denora Nunzio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (205 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
dasatinib
Duchenne muscular dystrophy cyclodextrin inclusion complex phase solubility studies paediatric age liquid formulation tumorspheres retinoblastoma topotecan penetration confocal microscopy poorly water soluble drug solubility enhancement grinding spray congealing neglected tropical diseases polymorph Norvir® ritonavir poorly soluble compound pediatric palatability assessment bioavailability flavor profile Interleukin-1 anakinra canakinumab innovative biotechnologies autoinflammatory disease Kawasaki disease systemic juvenile idiopathic arthritis personalized medicine child pediatrics neonates formulation product development formulation development oral parenteral topical inhaled intra nasal biopharmaceutics administration excipient NICU device medication error dosage form modified release drug delivery paediatric formulation development paediatric dosage forms chronic myeloid leukemia tyrosine kinase inhibitors pediatric age imatinib nilotinb ponatinib Orodispersible formulation pyrazinamide pediatric drug delivery tuberculosis design of experiments children edible films development design paediatric age-related palatable taste-masking acceptable |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Paediatric Formulation |
| Record Nr. | UNINA-9910557304003321 |
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Denora Nunzio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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