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Osteoarthritis: From Molecular Pathways to Therapeutic Advances
| Osteoarthritis: From Molecular Pathways to Therapeutic Advances |
| Autore | Veronese Nicola |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (306 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
osteoarthritis
cartilage type II collagen matrix metalloproteinases MMP-13 regulation inhibitor NO synthase Interleukin-1β chondrocytes mitochondrial dysfunction mesenchimal stem cells chondrocytic commitment autophagy miRNAs hydrostatic pressure adipokines visfatin Wnt/β-catenin mechanical loading obesity microRNA oxidative stress vibrational spectroscopy near-infrared spectroscopy infrared spectroscopy Raman spectroscopy early diagnosis exercise physical activity nutraceuticals dietary supplements inflammation aging inflammaging osteochondral explant culture joint modelling pharmacological assay native tissue analysis hexosamine biosynthetic pathway cartilage trauma post-traumatic osteoarthritis O-GlcNAcylation glucosamine cell death therapy sex as a biological variable whole transcriptome sequencing molecules TGF-β SMAD2/3 signaling linker modifications meniscus proteomics MRM ECM celecoxib glucosamine sulfate chondroprotection NF-κB cytokines chemokines pathogenesis biomarker chondrocyte IL-1β IFNγ, IL-17 IL-4 RNA-Seq hypertrophy remodeling angiogenesis chondroitin collagen methylsulfonylmethane vitamin C vitamin D hyaluronic acid |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Osteoarthritis |
| Record Nr. | UNINA-9910566461503321 |
Veronese Nicola
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Research of Pathogenesis and Novel Therapeutics in Arthritis / Chih-Hsin Tang
| Research of Pathogenesis and Novel Therapeutics in Arthritis / Chih-Hsin Tang |
| Autore | Tang Chih-Hsin |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI, , 2019 |
| Descrizione fisica | 1 electronic resource (366 p.) |
| Soggetto non controllato |
receptor activator of nuclear factor ?B
infliximab tripterine triptolide osteoblast tumor necrosis factor-alpha synovial cell anti-arthritis biosimilars Epstein-Barr virus cytokines SOX9 parathyroid hormone nitric oxide rat etanercept angiogenesis glycosylation mitogen activated protein kinase Th9 lymphocytes rheumatoid arthritis IL-6 clodronate bone erosion mesenchymal stem cells collagen-induced arthritis biological gene expression inflammatory arthritis osteoarthritis fraxinellone nuclear factor kappa B messenger RNA inflammation miRNA disease-modifying adipokines WNT glycoprotein 42 miR-199a-5p proliferation next-generation sequencing collagen osteoarthritis (OA) experimental arthritis bone morphogenetic protein TNF-? computational modeling basic research osteoclast therapeutics certolizumab pegol chondrocytes progenitor cells adjuvant arthritis adalimumab triterpenoid sclareol TNF? fibroblast growth factor 2 antibodies osteoblasts molecular pathology Th17 immunology obesity visfatin articular cartilage autoimmune biomarkers celastrol MAPK disease pathways IL1? arthritis bioinformatics anticitrullinated peptide antibodies drug delivery system antagonists shared epitope pathology SMA- and MAD-related protein small-molecule inhibitor transforming growth factor ? mice golimumab spinal fusion antirheumatic drug early osteoarthritis stem cell rheumatoid factor therapeutic antibody bisphosphonate osteoclastogenesis interleukin spondyloarthropathies clinical translation therapy Traditional Chinese medicine chemokines structure cell signaling microRNA |
| ISBN |
9783038970668
3038970662 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346843303321 |
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Tang Chih-Hsin
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| Basel, Switzerland : , : MDPI, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Selected Papers from XVI MaNaPro and XI ECMNP
| Selected Papers from XVI MaNaPro and XI ECMNP |
| Autore | Vasconcelos Vítor |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (214 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
marine-derived fungi
secondary metabolites polyketides drimanes meroterpenoids cytotoxicity benthic cyanobacteria tropical mangrove Guadeloupe phylogenetic diversity chemical diversity molecular networking antimicrobial activity proteasome inhibition dolabellane secosteroids soft coral marine natural products actinomycetes biofouling antifouling antibiofilm napyradiomycins hybrid isoprenoids drug discovery bioprospection Dysidea avara avarone/avarol redox-active compounds quinones and hydroquinones dioxothiazinoquinone Schistosoma mansoni Plasmodium falciparum Leishmania spp 3D-SAR analysis DFT studies PhenoTarget approach MRMS protein-ligand complex polycarpine holothurian diatom anti-fouling compounds saponins triterpene glycosides mass spectrometry Antarctica ascidian microbiome microbial diversity palmerolide A co-occurrence porphyrinoids annelida marine bioproducts HPLC-DAD toxicity photosensitizers chirality configurational analysis distance geometry NMR spectroscopy NOE data residual dipolar couplings Sarcophyton cherbonnieri cembranoid anti-inflammatory activity elastase release superoxide anion generation osteoarthritis amentadione preclinical osteoarthritis models marine compounds Cystoseira usneoides inflammation mineralization chondrocytes synoviocytes cartilage explants |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557670103321 |
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Vasconcelos Vítor
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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