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A Themed Issue in Honor of Professor Raphael Mechoulam: The Father of Cannabinoid and Endocannabinoid Research
| A Themed Issue in Honor of Professor Raphael Mechoulam: The Father of Cannabinoid and Endocannabinoid Research |
| Autore | Maccarrone Mauro |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (236 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
cannabinoid
MRI-1867 hybrid ligand CB1 receptor antagonist iNOS inhibitor rimonabant intracerebroventricular administration alcohol craving two-bottle paradigm drinking in the dark N-acyltransferase anandamide endocannabinoid phospholipase A2 cannabichromene cannabidiolic acid cannabidivarin cannabidivarinic acid phytocannabinoids tetrahydrocannabivarin 4'-fluoro-cannabidiol cannabinoid tetrad elevated plus maze catalepsy marble bury HUF-101 equilibrative nucleoside transporter CB1 biased signaling functional selectivity G-protein β-arrestin cannabigerol anti-inflammatory obesity cannabinoid receptor 2 (CB2R) microglia inflammaging memory lipofuscin aminoalkylindole allodynia antinociception cannabinoid receptor CP55940 JWH-018 K2 pravadoline spice WIN55212-2 type 1 cannabinoid receptor CB1 cholesterol hippocampus frontal cortex synaptosomes rescue model anti-CB1 antibody cannabinoids GPR55 receptors VCE-006.1 chromenopyrazole Parkinson's disease 6-hydroxydopamine lipopolysaccharide amyotrophic lateral sclerosis mSOD1 mice TDP-43 transgenic mice PPARs gut microbiome intestine ghrelin LEAP2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Themed Issue in Honor of Professor Raphael Mechoulam |
| Record Nr. | UNINA-9910566470103321 |
Maccarrone Mauro
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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ABC Transporters in Human Diseases
| ABC Transporters in Human Diseases |
| Autore | Falguières Thomas |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (494 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
ABC transporters
drug action regulatory extension regulatory insertion mechanism of action MRP1 MRP4 breast cancer proliferation migration invasion cAMP ABCG2 ABCB1 blood-brain barrier PET Alzheimer's disease beta-amyloid tariquidar erlotinib ABCG5 ABCG8 ATP-binding cassette transporter cholesterol polar relay sitosterolemia 5' untranslated region cis-acting elements ABCA subfamily bioinformatics ABC transporter therapy response disease-free survival next-generation sequencing competitive allele-specific PCR P-glycoprotein amyloid-beta neuron SK-N-SH gene therapy AAV PFIC BSEP ABCB11 bile salts intrahepatic cholestasis chaperones PFIC2 BRIC ATP-binding cassette transporter A1 (ABCA1) cholesterol homeostasis reverse cholesterol transport HDL-C dyslipidemia type 2 diabetes microparticles ABCG2 genotype clinico-genetic analysis ethnic specificity genetic variations precision medicine rare variant Roma serum uric acid SUA-lowering therapy urate transporter bile secretion ABCB4 ABCC2 ABCG5/G8 molecular partners phytosterol xenosterol atherosclerosis gall stone ABC transporter ABC (ATP-binding cassette) transporters multidrug resistance transport trafficking urate mutations polymorphisms ABCC6 TNAP NT5E Pseudoxanthoma elasticum (PXE) cancer membrane protein functional divergence calcification pseudoxanthoma elasticum generalized arterial calcification of infancy pyrophosphate therapies ABCA7 phagocytosis Aβ peptides yeast multidrug transporter anticancer antifungal resistance mechanism peroxisome adrenoleukodystrophy fatty acids gout early-onset gout hyperuricemia uric acid BCRP single nucleotide polymorphism SNP homology modeling substrate-binding site cellular ATP efflux mutagenesis intracellular traffic MDR3 phosphatidylcholine RAB GTPase taxol drug transport |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674029103321 |
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Falguières Thomas
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Adipokines 2.0
| Adipokines 2.0 |
| Autore | Büchler Christa |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (406 p.) |
| Soggetto non controllato |
lipids
cathepsins neurodegeneration tocilizumab SGBS adipocytes chemerin receptors cholesterol metabolically healthy obese energy metabolism adipose-brain axis EP3 receptor leptin rheumatoid arthritis excessive gestational weight gain in vitro fat regain secreted frizzled-related protein 5 PCOS EP4 receptor leukocyte exchange protein directly activated by cAMP isoform 2 (EPAC2) extracellular remodeling insulin osteoarthritis lipid metabolism fat mass Tango bioassay fatty liver free fatty acids label-free proteomic profiling interleukin(IL)-33 sick fat polycystic ovary syndrome early-life programming inflammation gestational diabetes glucose restriction adipokines neonatal anthropometry epicardial adipose tissue (EAT) oestrous cycle Cardiovascular Diseases (CVDs) triglycerides G protein-coupled receptor 1 testicular pathologies prognosis ovary ICU biologic activity preeclempsia adipokine critical illness early pregnancy myokine liver steatosis C-C chemokine receptor-like 2 testis stimulating growth factor 2 (ST2) pig fitness human granulosa cells obesity proteolysis annexins adipose tissue biomarker ghrelin brain health sepsis adiponectin rheumatic diseases chemokine-like receptor 1 follicular fluid glucose homeostasis resistin Nonalcoholic fatty liver disease prostaglandin E2 (PGE2) visceral fat microglia weight regain complement factors alpha-fetoprotein polycystic ovary morphology chemerin cancer depression hypertension hypothalamus |
| ISBN | 3-03928-587-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404092003321 |
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Büchler Christa
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Lipidomics: Biomedicine, Nutrients and Methodology
| Advances in Lipidomics: Biomedicine, Nutrients and Methodology |
| Autore | Montero Olimpio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
chronic kidney disease
leptin fatty acids adipose tissue adipocytes adipogenesis differential mobility spectrometry (DMS) lipidomics lipidyzer mass spectrometry metabolomics phenotyping Simpson-Golabi-Behmel syndrome (SGBS) COX CYP450 LOX oxylipins PUFAs UPLC-MS/MS copper Wilson’s disease lipidomic liquid chromatography tandem mass spectrometry molecular network dry eye disease hyperosmolarity cardiovascular disease heart failure myocardial infarction obesity diabetic cardiomyopathy dilated cardiomyopathy lipids odd chain lipids lipid profiling Folch protein precipitation sample preparation relative lipid composition (Mol%) atopic dermatitis SHARPIN-deficient mice flow-injection mass-spectrometry predictive elastic net immunotherapy cancer biomarkers metabolism cancer cell membranes fatty acid biosynthesis essential fatty acids desaturase enzymes fatty acid signaling fatty acid biomarker sapienic acid sebaleic acid molecular nutrition inflammation drug-induced liver injury biomarker plasma lipid profiles ssRNA+ virus membrane fusion lipid metabolism cholesterol sphingolipids phosphatidylinositol SARS-CoV glycolipidomics GIPC glycosyl inositol phospho ceramides Lipid Data Analyzer ultra-high pressure liquid chromatography high-resolution mass spectrometry LC-MS automated annotation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Advances in Lipidomics |
| Record Nr. | UNINA-9910557497303321 |
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Montero Olimpio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biocatalysis and Pharmaceuticals: A Smart Tool for Sustainable Development
| Biocatalysis and Pharmaceuticals: A Smart Tool for Sustainable Development |
| Autore | Alcantara Andres R |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (176 p.) |
| Soggetto non controllato |
biotransformations
glycosidases bacteria OcUGT1 antioxidant activity glycodiverfication benzoxathiepins coprostanol 7-methylguanosine iodide sulfuretin chondroitin sulfates 7-methylguanine arabinoside iodide 7-methyl-2?-deoxyguanosine iodide microalgae chitosan oligosaccharides deacetylation degree cholesterol Tecadenoson esterase metabolic pathways chitinases alcohol transglycosylation reaction MALDI-TOF photooxidation aqueous solubility ?-transaminase cascade nutraceutical antimuscarinic agents extraction rutin oligomers Alcalase® HPSEC Cladribine purine nucleoside phosphorylase pleiotropic effects biotransamination amino acid stereoselective laccase activity biocatalysis Ribavirin lyases chitosanases anti-inflammatory glycosaminoglycan polysaccharides amine transaminases ester hydrolysis Spirulina asymmetric synthesis reductive amination glycosyltransferase statins stereoselective synthesis xanthine oxidase inhibition reduction reaction pig liver esterase (PLE) |
| ISBN | 3-03921-709-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Biocatalysis and Pharmaceuticals |
| Record Nr. | UNINA-9910367748703321 |
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Alcantara Andres R
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Carborane: Dedicated to the Work of Professor Alan Welch
| Carborane: Dedicated to the Work of Professor Alan Welch |
| Autore | Stogniy Marina Yu |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (114 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
carboranes
DFT reaction pathways boron chemistry o-carborane sulfa-Michael addition reaction cysteine boron neutron capture therapy o-carborane decapitation labeled compound 1,1'-bis(o-carborane) deboronation metalation bis(nickelation) diastereoisomers stereospecific boron clusters liquid crystals fluorescence cholesterol nido-carborane nitrilium derivatives nickel(II) half-sandwich complexes synthesis structure Lewis acid carborane carbonium ylide tetrel bond quantum chemistry electron density ELF iodo derivatives dihalogen bond X-ray structure quantum chemical calculations iron bis(1,2-dicarbollide) chromium bis(1,2-dicarbollide) tetramethyltetrathiafulvalene tetramethyltetraselenafulvalene radical-cation salts crystal and molecular structure electric conductivity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Carborane |
| Record Nr. | UNINA-9910566473603321 |
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Stogniy Marina Yu
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chemical Biology of Sterols, Triterpenoids and Other Natural Products: A Themed Issue in Honor of Professor W. David Nes on the Occasion of His 65th Birthday
| Chemical Biology of Sterols, Triterpenoids and Other Natural Products: A Themed Issue in Honor of Professor W. David Nes on the Occasion of His 65th Birthday |
| Autore | Guo De-an |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (256 p.) |
| Soggetto non controllato |
high-fat high-carbohydrate diet
toxicity oxysterol squalene cyclase sterol content sterolomics Polystichum Smith-Lemli-Opitz syndrome antifungals alkaloid cycloartenol synthase degeneration phytosterol Rhizopus arrhizus fibroblasts pod-blast fern cholesterol cytotoxic activity N-methylpiperidine. reductive deamination genetic disease isoprenoid steroid atherosclerosis granatane antioxidant wound healing development enzyme-assisted derivatization maturity terpene keratinocytes C4-demethylation complex (C4DMC) ?-sitosterol mesocarp sterol biosynthesis mechanism-based inactivators Mucorales gas chromatography-mass spectrometry (GC-MS) Girard reagent ROS sterol pattern N-methylcadaverine ?-tocopherol electrospray ionization-mass spectrometry human African trypanosomiasis HUVECs lipidomics campesterol triterpene oxyphytosterol leishmania Chagas disease LOX-1 sterol C24-methyltransferase antifungal effectivity ergosterol biosynthesis hormone glucose homeostasis retina solanaceae cholestanoic acid algal sterols cell migration withanolides insulin resistance Zingiber officinale posaconazole synthesis pre-diabetes pharmacognosy sterol 4-methylsterol oleanolic acid antiparasitic drugs lupeol oilseed aurelianolides divalent metal co-factor ligation bile alcohol phytosterols azoles infectious disease gingerols UV-radiation oil bodies ZnO sterol 14?-demethylase stigmasterol |
| ISBN | 3-03897-417-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Chemical Biology of Sterols, Triterpenoids and Other Natural Products |
| Record Nr. | UNINA-9910346835903321 |
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Guo De-an
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics
| Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics |
| Autore | Tutone Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (387 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
3D-QSAR
pharmacophore modeling ligand-based model HDACs isoform-selective histone deacetylase inhibitors aminophenylbenzamide hERG toxicity drug discovery fingerprints machine learning deep learning gene expression signature drug repositioning approaches RNA expression regulation high-throughput virtual screening dual-target lead discovery neurodegenerative disorders Alzheimer's disease dual mode of action multi-modal nicotinic acetylcholine receptor acetylcholinesterase molecular docking methotrexate drug resistance human dihydrofolate reductase virtual screening molecular dynamics simulation epitope binning epitope mapping epitope prediction antibody:antigen interactions protein docking glycoprotein D (gD) herpes simplex virus fusion proteins Src inhibitors pharmacophore model molecular dynamics simulations in silico COX-2 inhibitors molecular modeling sodium-glucose co-transporters 2 FimH uropathogenic bacteria urinary tract infections diabetes drug-resistance mutations HIV-2 protease structural characterization induced structural deformations SARS-CoV-2 COVID-19 multiprotein inhibiting natural compounds MD simulation 3CL-Pro antivirals docking simulations drug repurposing consensus models binding space isomeric space MRP4 SNPs variants protein threading modeling molecular dynamics binding site hTSPO PK11195 cholesterol homology modeling molecular dynamics (MD) simulation carbon nanotubes Stone-Wales defects haeckelite defects doxorubicin encapsulation drug delivery system binding free energies noncovalent interactions main protease mutants inhibitors PF-00835231 Mycobacterium tuberculosis tuberculosis proteasome natural compounds multiscale multitargeting polypharmacology computational biology drug repositioning structural bioinformatics proteomic signature skin aging oxidative stress aging progression mechanism genome-wide genetic and epigenetic network (GWGEN) systems medicine design multiple-molecule drug immunoproteasome non-covalent inhibitors MD binding metadynamics induced-fit docking |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Computational Approaches |
| Record Nr. | UNINA-9910557519403321 |
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Tutone Marco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cyclodextrin Chemistry and Toxicology
| Cyclodextrin Chemistry and Toxicology |
| Autore | Isidori Marina |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
cyclodextrin
sulfamethazine zwitterion host-guest complex thermodynamics nanosponges β-cyclodextrin glutathione cancer multicellular spheroids inclusion complexes solubilization nanosponge nanocarriers pharmaceutical applications molecular recognition phenomena molecular dynamics simulations drug delivery drug concentration dyeing textile finishing textile wastewater cyclodextrins HPβCD budesonide inflammation ROS Akt HDAC cholesterol medical imaging contrast agents α-cyclodextrin γ-cyclodextrin MRI PET CT SPECT PAI Cinnamomum osmophloeum linalool microencapsulation cyclodextrin inclusion solution-phase solid state antiretroviral 3-hydroxyflavone (3HF) γ-cyclodextrin (γ-CD) excited-state proton transfer (ESPT) molecular dynamics (MD) density functional theory (DFT) cyclodextrin polymers synthesis separation science materials science biomedicine retinal explant cytotoxicity uptake risperidone inclusion complex randomly methylated β-cyclodextrin compatibility studies excipients solubility stability aggregation doxorubicin nanoparticles alveograph wheat dough bread staling |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585942703321 |
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Isidori Marina
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dietary Behavior and Physical Activity in Children and Adolescents
| Dietary Behavior and Physical Activity in Children and Adolescents |
| Autore | Hebestreit Antje |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (358 p.) |
| Soggetto non controllato |
parent
DAGIS Study noncommunicable diseases PANDiet index preschool children dietary assessment methods consumption behavior mothers children cholesterol prevention validation knowledge blood pressure determinants adolescents waist circumference home food environment eating behavior and Ile251Leu Emotion-Induced Eating Scale CEBQ vitamin early childhood family meals preschool breakfast whole diet migration status healthy diet adherence Healthy Eating Index exercise food and beverage consumption children’s-dietary inflammatory index food diary primary school consumption behaviors inflammation weight status dietary supplements I.Family dietary quality cluster analysis BMI reduced rank regression preferences KiGGS IDEFICS study food frequency questionnaire health Melanesian cardiovascular psychometric Pacific collaboration sugar-sweetened beverage health behaviour breastfeeding choice self-weight perception dairy dietary screener Physical activity growing up milk pediatric body composition mineral obesity prevention eating behaviour psychological eating style obesity food choice direct observation socioeconomic disparities validation study dietary behavior nutrient intake quality food parenting practices nutrition preschoolers epidemiological transition EsKiMo young populations intervention dietary habits child sweet preference epidemiology dietary intake nutrition risk formula milk diet surveillance energy balance-related behaviors sedentary behavior overweight public health taste preference calcium negative emotions vegetable intake MyHeARTs physical activity nutritional adequacy dietary pattern cross-classification diet quality screen time childhood obesity principal component analysis food intake |
| ISBN | 3-03921-601-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367739403321 |
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Hebestreit Antje
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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