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Cellular Senescence in Health, Disease and Aging: Blessing or Curse?
| Cellular Senescence in Health, Disease and Aging: Blessing or Curse? |
| Autore | Riessland Markus |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (112 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
γH2AX
Alzheimer's disease DNA damage mild cognitive impairment senescence secreted protein acidic and rich in cysteine regeneration homeostasis cellular senescence biology of aging neurodegeneration brain geroscience senolytics tauopathy cancer stress response post-mitotic neuronal senescence amyotrophic lateral sclerosis senescence-associated secretory phenotype (SASP) cell-cycle melanoma pancreatic adenocarcinoma tumor infiltration chemotherapy resistance prostate inflammation AIM2 inflammasome POP3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cellular Senescence in Health, Disease and Aging |
| Record Nr. | UNINA-9910557382703321 |
Riessland Markus
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Aspects of Cancer Stem Cell Biology : Implications for Innovative Therapies
| New Aspects of Cancer Stem Cell Biology : Implications for Innovative Therapies |
| Autore | Cavallaro Ugo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (208 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Cadherin 11
WNT signaling β-catenin cancer stem cells TNBC early breast cancer bevacizumab neoadjuvant chemotherapy ALDH1 solid cancer chemo-resistance HDAC inhibitors head and neck squamous cell carcinoma SRC dasatinib saracatinib EC-8042 Ovarian cancer Wnt signaling tumor progression therapy resistance exosomes oral cancer risk oral epithelial dysplasia SOX2 immunohistochemistry oral squamous cell carcinoma genome-wide transcriptome lung cancer ATAC-seq RNA-seq CSCs NSCLC B4GALT1 LUAD breast cancer lipid metabolism therapeutic resistance bowel cancer organoid tumoroid colorectal colon stem cell chemotherapy resistance ovarian cancer cancer stem cell genetic heterogeneity SNP array L1CAM chemoresistance epithelial-mesenchymal transition cancer therapy cell adhesion molecule |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | New Aspects of Cancer Stem Cell Biology |
| Record Nr. | UNINA-9910557112003321 |
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Cavallaro Ugo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting STAT3 and STAT5 in Cancer
| Targeting STAT3 and STAT5 in Cancer |
| Autore | Moriggl Richard |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (578 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
multiple myeloma
STAT3 S3I-1757 nanoparticle CD38 siRNA/RNAi polyethylenimine PEI lipopolyplex siRNA delivery glioma glioblastoma STAT5 AKT ERK1/2 prolactin androgens prostate cancer knockout escape mechanisms stem/progenitor cells cell hierarchy cancer CD4+ T cells CD8+ T cells myeloid cells immune check point hepatitis C virus (HCV) cirrhosis hepatocellular carcinoma (HCC) endoplasmic reticulum (ER) stress oxidative stress (OS) unfolded protein response (UPR) microRNA-122 (miR-122) nuclear factor erythroid 2-related factor 2 (NRF2) signal transducer and activator of transcription 3 (STAT3) hepatocyte nuclear factor 4 alpha (HNF4A) solid cancers cell cycle apoptosis inflammation mitochondria stemness tumor suppression melanoma autoimmune disease immunotherapy tumor-immune cell interactions breast cancer PD-L1 M2 macrophages NK cells STAT3 inhibitor XIII hedging transaction costs dynamic programming risk management post-decision state variable cancer progression cancer-stem cell cytokine therapy resistance metastasis immunosuppression tumor microenvironment proliferation tyrosine kinase 2 JAK family of protein tyrosine kinases signal transducer and activator of transcription cytokine receptor signaling gain-of-function mutation tumorigenesis ADAM17 interleukin-6 trans-signaling epidermal growth factor receptor (EGF-R) shedding metalloprotease tumor necrosis factor alpha (TNFα) inflammation associated cancer colon cancer lung cancer SH2 domain mutations autosomal-dominant hyper IgE syndrome inflammatory hepatocellular adenomas T-cell large granular lymphocytic leukemia T-cell prolymphocytic leukemia growth hormone insensitivity syndrome nuclear pore complex nuclear transport receptors nucleocytoplasmic shuttling targeting tumor-associated macrophages adoptive T cell therapy immune suppression STAT transcription factors JAK STAT T-PLL T-cell leukemia meta-analysis STAT5B signaling small-molecule inhibitors cancer models companion animals comparative oncology pharmacological inhibitor STAT5 signaling chemotherapy resistance myeloid leukemia heat shock proteins chaperones stabilization targeted therapy ovarian cancer hematopoietic cancers therapeutic targeting pharmacological inhibitors mTOR Bone Marrow Failure Syndromes lymphocytes lymphoma T-cells RHOA NGS MPN JAK2 V617F neoplastic stem cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557623503321 |
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Moriggl Richard
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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