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Cellular Senescence in Health, Disease and Aging: Blessing or Curse?
| Cellular Senescence in Health, Disease and Aging: Blessing or Curse? |
| Autore | Riessland Markus |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (112 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
AIM2 inflammasome
Alzheimer's disease amyotrophic lateral sclerosis biology of aging brain cancer cell-cycle cellular senescence chemotherapy resistance DNA damage geroscience homeostasis inflammation melanoma mild cognitive impairment n/a neurodegeneration neuronal senescence pancreatic adenocarcinoma POP3 post-mitotic prostate regeneration secreted protein acidic and rich in cysteine senescence senescence-associated secretory phenotype (SASP) senolytics stress response tauopathy tumor infiltration γH2AX |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cellular Senescence in Health, Disease and Aging |
| Record Nr. | UNINA-9910557382703321 |
Riessland Markus
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Aspects of Cancer Stem Cell Biology : Implications for Innovative Therapies
| New Aspects of Cancer Stem Cell Biology : Implications for Innovative Therapies |
| Autore | Cavallaro Ugo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (208 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
ALDH1
ATAC-seq B4GALT1 bevacizumab bowel cancer breast cancer Cadherin 11 cancer stem cell cancer stem cells cancer therapy cell adhesion molecule chemo-resistance chemoresistance chemotherapy resistance colon colorectal CSCs dasatinib early breast cancer EC-8042 epithelial-mesenchymal transition exosomes genetic heterogeneity genome-wide HDAC inhibitors head and neck squamous cell carcinoma immunohistochemistry L1CAM lipid LUAD lung cancer metabolism neoadjuvant chemotherapy NSCLC oral cancer risk oral epithelial dysplasia oral squamous cell carcinoma organoid ovarian cancer Ovarian cancer RNA-seq saracatinib SNP array solid cancer SOX2 SRC stem cell therapeutic resistance therapy resistance TNBC transcriptome tumor progression tumoroid Wnt signaling WNT signaling β-catenin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | New Aspects of Cancer Stem Cell Biology |
| Record Nr. | UNINA-9910557112003321 |
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Cavallaro Ugo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting STAT3 and STAT5 in Cancer
| Targeting STAT3 and STAT5 in Cancer |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (578 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
ADAM17
adoptive T cell therapy AKT androgens apoptosis autoimmune disease autosomal-dominant hyper IgE syndrome Bone Marrow Failure Syndromes breast cancer cancer cancer models cancer progression cancer-stem cell CD38 CD4+ T cells CD8+ T cells cell cycle cell hierarchy chaperones chemotherapy resistance cirrhosis colon cancer companion animals comparative oncology cytokine cytokine receptor signaling dynamic programming endoplasmic reticulum (ER) stress epidermal growth factor receptor (EGF-R) ERK1/2 escape mechanisms gain-of-function mutation glioblastoma glioma growth hormone insensitivity syndrome heat shock proteins hedging hematopoietic cancers hepatitis C virus (HCV) hepatocellular carcinoma (HCC) hepatocyte nuclear factor 4 alpha (HNF4A) immune check point immune suppression immunosuppression immunotherapy inflammation inflammation associated cancer inflammatory hepatocellular adenomas interleukin-6 JAK JAK family of protein tyrosine kinases JAK2 V617F knockout lipopolyplex lung cancer lymphocytes lymphoma M2 macrophages melanoma meta-analysis metalloprotease metastasis microRNA-122 (miR-122) mitochondria MPN mTOR multiple myeloma mutations myeloid cells myeloid leukemia n/a nanoparticle neoplastic stem cells NGS NK cells nuclear factor erythroid 2-related factor 2 (NRF2) nuclear pore complex nuclear transport receptors nucleocytoplasmic shuttling ovarian cancer oxidative stress (OS) PD-L1 PEI pharmacological inhibitor pharmacological inhibitors polyethylenimine post-decision state variable prolactin proliferation prostate cancer RHOA risk management S3I-1757 SH2 domain shedding signal transducer and activator of transcription signal transducer and activator of transcription 3 (STAT3) siRNA delivery siRNA/RNAi small-molecule inhibitors solid cancers stabilization STAT STAT transcription factors STAT3 STAT3 inhibitor XIII STAT5 STAT5 signaling STAT5B signaling stem/progenitor cells stemness T-cell large granular lymphocytic leukemia T-cell leukemia T-cell prolymphocytic leukemia T-cells T-PLL targeted therapy targeting therapeutic targeting therapy resistance trans-signaling transaction costs tumor microenvironment tumor necrosis factor alpha (TNFα) tumor suppression tumor-associated macrophages tumor-immune cell interactions tumorigenesis tyrosine kinase 2 unfolded protein response (UPR) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557623503321 |
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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