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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (606 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
benzofurans
chemical synthesis cytotoxic properties HeLa MOLT-4 K562 anticancer anti-neuroinflammation coumarin dihydroartemisinin flavonoids allene E-stereoselective regioselective anti-cancer activity cyanopyridone substituted pyridine pyridotriazine pyrazolopyridine thioxotriazopyridine anticancer activity HepG2 antitumor activity computational docking MDM2-p53 interaction xanthones yeast-based assays estrone derivatives hydrazine N-substituted pyrazoline anti-ovarian cancer topoisomerase II inhibitor kinase inhibitor antiproliferative agent urea synthesis antiproliferative activity apoptosis indoleamine 2,3-dioxygenase inhibitor anti-tumor immune modulation tryptophan metabolism taxoids βIII-tubulin P-glycoprotein drug resistance thiopene thienopyrimidinone thiazolidinone breast cancer benzofuran–pyrazole nanoparticles cytotoxic activity PARP-1 inhibition 3,6-dibromocarbazole 5-bromoindole carbazole actin migration Thienopyrimidine Pyrazole PI3Kα inhibitor quinazolin-4(3H)-one quinazolin-4(3H)-thione Schiff base antioxidant activity DFT study ortho-quinones beta-lapachone tanshione IIA PI3Ks PI3Kδ inhibitors 2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide anticancer agents protein–protein interactions virtual screening mimetics drug discovery bivalency polyvalency antitumor cell cycle ovarian cancer P-MAPA IL-12 TLR signaling inflammation chemoresistance 4-(pyridin-4-yloxy)benzamide 1,2,3-triazole c-Met natural product anticancer agent zampanolide Talazoparib PARP inhibitor prodrug o-nitro-benzyl photoactivatable protecting groups salinomycin overcoming drug resistance tumor specificity synergy 5-fluorouracil gemcitabine amides/esters colchicine analogs thiocolchicine colchiceine antimitotic agents hydrates dihydropyranoindole HDAC inhibitors neuroblastoma aromatase MCF-7 NIH3T3 benzimidazole triazolothiadiazine docking ADME organosilicon compounds SILA-409 (Alis-409) SILA-421 (Alis-421) multidrug resistance (MDR) reversal ABCB1 (P-glycoprotein) colon cancer colchicine amide colchicine sulfonamide tubulin inhibitors docking studies crystal structure PROTACs protein degradation IGF-1R Src protein kinase phenylpyrazolopyrimidine enzyme inhibition molecular simulation androgen receptor prostate cancer enzalutamide apalutamide darolutamide triple-negative breast cancer cytotoxicity chrysin analogues flavonoid anticancer compounds |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Feature Papers in Eng
| Feature Papers in Eng |
| Autore | Gil Bravo Antonio |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (236 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
hydrofoil optimization
NSGA-II CFD XFOIL NACA 63815 bezier curve ultrasound application glass bottles fruit juice foam drainage foaming behavior martensitic phase transformation (MPT) grain misorientation (GMO) surface roughening (Ra) grain size (Dg) solid oxide fuel cell computational fluid dynamics sensitivity analysis optimization sand retention test sand control devices sand production sand replication SAGD probabilistic risk assessment multi-hazards nuclear safety dry-cured ham food-grade chemical coating mechanical performance characteristics chemical treatment ham nets pest management mechanical test mesh fabric artificial magnetic conductor (AMC) specific absorption rate (SAR) coplanar waveguide (CPW) antenna magneto-dielectric (MD) mobile phones wireless communications optical multi-band systems physical layer modeling fiber-optic communications commercially available components planar transformer eco-design environmental impact evaluation product efficiency DC-DC converter dual active bridge (DAB) life cycle optimization fuel optimization low cost HEV optimum hybridization bubble nucleation gas-liquid systems supersaturation step-down pressure Fick's second law diffusion characteristic time Q factor damping model transitional flow regime viscous flow regime MEMS oscillator bending modes zirconium phosphate titanium phosphate nanolayered phosphates nanofibrous titanium phosphate chemical synthesis crystal structure technological applications drug delivery biomedical applications |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595068303321 |
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Gil Bravo Antonio
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Magnetic Nanomaterials
| Magnetic Nanomaterials |
| Autore | Del Bianco Lucia |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (234 p.) |
| Soggetto topico |
Technology: general issues
History of engineering & technology |
| Soggetto non controllato |
disordered magnetism
super-spin glass glassy correlation length magnetic freezing nanogranular Au/Fe-oxide Fe-oxide nanocrystallites synthetic antiferromagnet exchange bias interlayer exchange coupling vibrating sample magnetometry CoFeB thermally assisted magnetic scanning probe lithography magnetron sputtering nanoparticles sol-gel Raman spectroscopy UV-blue photoluminescence ZnNiO Kubelka-Munk function Burstein-Moss shift substitutional doping FePd alloy electrodeposition technique magnetic properties structural characterisation ferrimagnetic materials superparamagnetism magnetic hysteresis magnetic materials magnetic nanoparticles nanocomposites nanowires martensitic transition Heusler alloys magnetic shape memory alloys twin boundary epitaxial Ni-Mn-Ga films transmission electron microscopy magnetic anisotropy iron nitrides III-nitrides nanocrystals density functional theory magnetic hyperthermia magneto-sonoporation stem cells superparamagnetic iron oxide particles cell labelling ultrasounds osteogenesis bone tissue engineering magnetic aggregates magnetic interactions core/shell nanoparticles multicore nanoparticles hybrid systems mixed nanoparticle systems chemical synthesis magnetic heating |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557610803321 |
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Del Bianco Lucia
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Bioactive Peptides: Structure, Function, and Therapeutic Potential
| Marine Bioactive Peptides: Structure, Function, and Therapeutic Potential |
| Autore | Ovchinnikova Tatiana V |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (442 p.) |
| Soggetto non controllato |
cone snail
tilapia animal models BRICHOS domain recombinant peptide calcium absorption plastein reaction antioxidant activity endothelial dysfunction C3a lung cancer invertebrate immunity identification zinc bioavailability NA-inhibitory peptide nuclear magnetic resonance (NMR) review ACE-inhibitory activity intestinal absorption hairtail (Trichiurus japonicas) DU-145 cells peptide crustacean venom duct Kalloconus drug design molecular symmetry arenicin ?-helix APETx2 conotoxins functional diversity docking conotoxin neuraminidase angiotensin II polychaeta influenza virus phylogeny gene expression host defense peptide Perinereis aibuhitensis anti-diabetic activity conopeptides SHRs Chlorella pyrenoidosa protein hydrolysate (CPPH) metastasis Caco-2 cell monolayer Nrf2 caco-2 cells HUVEC PYP15 sea cucumber decapeptide cytotoxic arenicin-1 marine peptides cell proliferation Conus Conus ateralbus self-production of hydrogen peroxide antimicrobial activity molecular dynamics machine learning tachyplesins ion channels gut microbiota Anthopleura anjunae oligopeptide signaling pathways half-fin anchovy hydrolysates NF-?B Chlorella pyrenoidosa protein hydrolysate-calcium chelate (CPPH-Ca) antihypertensive effect QAGLSPVR antimicrobial peptides vasculogenic mimicry antibacterial ?-hairpin innate immunity transcriptome sequencing HIF-1? Gracilariopsis lemaneiformis function ACE-inhibitory peptide complement peptide-zinc complex structure-activity relationship multi-functional peptides cod skin adsorption Maillard reaction products molecular docking antibacterial peptide PI3K/AKT/mTOR signaling pathway Arenicola marina antimicrobial peptide Rana-box acid-sensing ion channel Neptunea arthritica cumingii apoptosis membrane damage proteolytic system toxin polyphemusins computational studies muscle oyster zinc-binding peptide abalone pain relief transport routes cytotoxicity dexamethasone cell death host?microbe relationship anti-LPS factor MMPs protein synthesis structure Pyropia yezoensis peptide cone snails chemical synthesis prostate cancer Ugr 9-1 myotube atrophy |
| ISBN | 3-03921-533-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Marine Bioactive Peptides |
| Record Nr. | UNINA-9910367750603321 |
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Ovchinnikova Tatiana V
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sulfur-Containing Marine Bioactives
| Sulfur-Containing Marine Bioactives |
| Autore | Palumbo Anna |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (140 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
propylene glycol alginate sodium sulfate
angiogenesis invasion FGF2 MMP-2 MMP-9 fucoidan fucan age-related macular degeneration VEGF oxidative stress Laminaria hyperborea brown seaweed extracts proliferation molecular weight retinal pigment epithelium thiopeptide antibiotic screening structure elucidation natural products rare actinobacteria carbohydrate sulfotransferase carrageenan cytochrome P450 galactose-6 sulfurylase red alga reproduction stages WD 40 sulfavants adjuvant immunomodulatory activity colloid aggregates algae antioxidant diatoms light nitric oxide ovothiol biofouling marine coatings anti-settlement chemical synthesis sulfated gallic acid eco-friendly Tetraselmis suecica autotrophic culture heterotrophic culture exopolysaccharides antioxidant capacity cytotoxic effects on tumor cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557113603321 |
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Palumbo Anna
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthesis of Marine Natural Products and Molecules Inspired by Marine Substances II
| Synthesis of Marine Natural Products and Molecules Inspired by Marine Substances II |
| Autore | Manzo Emiliano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (111 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
In-silico drug design
virtual screening Avicennia alba gag polyprotein homology modeling ADMET molecular dynamics simulation divergent total synthesis marine natural products tetracyclic meroterpenoids aureol (−)-majusculoic acid anti-inflammation LPS CCK-8 animal studies marine alkaloids biological activity cancer cardiovascular diseases inflammation chemical synthesis ilamycins rufomycins cyclomarins tuberculosis malaria cyclopeptides biosynthesis total synthesis natural products |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557724503321 |
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Manzo Emiliano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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