Advances in Multiple Sclerosis Research-Series I |
Autore | Matsoukas John |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (334 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
multiple sclerosis
inflammation oxidative biomarker sample size autoimmune encephalitis plasma exchange autoimmunity immunotherapeutics clinical outcomes major depression bupropion S-adenosylmethionine vitamin D3 yoga craniopharyngioma fractionated stereotactic radiation treatments sphenoid sinusitis cranial nerve-VI palsy autoimmune diseases immune thrombocytopenic purpura alemtuzumab antibodies against GluR3 peptide cognitive impairment diagnosis neuropsychological assessment short intracortical inhibition intracortical facilitation fampridine walking disability TSPAN32 tetraspanins cellular immunity memory T cells tDCS neuroimaging positron emission tomography cerebral blood flow probiotics Streptococcus thermophilus ST285 MBP83–99 peptide mannan immune modulation agonist peptide gut microbiome gut–brain axis metagenomics disease-modifying treatments MS vaccine immunomodulation carriers B cell receptor delivery methods immunotherapy monoclonal antibodies T cell receptor tolerance diagnostic markers immunoglobulins kappa free light chains antigen-specific immunotherapies tolerogenic vaccines tolerance induction central nervous system myelin peptides myelin basic protei proteolipid protein myelin oligodendrocyte glycoprotein nanotechnology drug delivery nanosystems lipids polymers vaccines nanoparticles antigen-specific immunotherapy experimental autoimmune encephalomyelitis neurodegeneration chloroquine EAE dendritic cells microglia astrocytes oligodendrocytes conformational analysis peptides altered peptide ligands NMR spectroscopy NOE-constraints molecular dynamic trimolecular complex Multiple Sclerosis early-onset adult-onset Human Leucocyte Antigens immunogenetics clinical phenotype clinical outcome therapeutics antibody detection ELISA multivalency N-glucosylated peptide epitopes peptide conjugation MOG35-55 Graphite/SiO2 electrode voltammetry HPLC MS drugs |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557385403321 |
Matsoukas John | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Antiviral Agents |
Autore | Adamson Catherine |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (386 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
Zika virus
nucleoside analogues antiviral agents NS5 prodrugs ProTides neural stem cells RNA-dependent RNA polymerase cytomegalovirus latent infection TALEN Surveyor nuclease mutation detection assay ie-1 gene quantitative real-time PCR Epstein-Barr virus herpes viruses lytic gene expression Burkitt lymphoma cells clozapine antipsychotic drug antiviral drug enteroviruses coxsackievirus B4 persistent infection fluoxetine resistance mutations herpes B virus macacine herpesvirus-1 genistein flavonoids acyclovir ganciclovir Plantago asiatica Clerodendrum trichotomum RSV therapeutic effects acteoside human antimicrobial peptides antiviral strategies defensins cathelicidins hepcidins transferrins influenza A virus brevilin A antiviral sesquiterpene lactone replication PRRSV polyethylenimine PEI virion internalization endocytosis HIV pediatrics Ethiopia pre-treatment drug resistance combination antiretroviral therapy (cART) dried plasma spots dried blood spots sphingolipids glycosphingolipids viruses lipid biosynthesis flavivirus Japanese encephalitis virus furin inhibitor precursor membrane protein measles virus central nervous system tropism treatments porcine reproductive and respiratory syndrome virus ginsenoside Rg1 antiviral activity pro-inflammatory factor NF-κB signaling pathway acute/latent infection congenital infection antiviral agent therapeutic strategies nucleic acid-based therapeutic approach HCMV vaccine adoptive cell therapy Rev response element chemical footprinting SHAPE drug discovery branched peptides herpesvirus immediate-early IE1 IE2 ribozyme RNA interference CRISPR/Cas small molecule orthohantavirus phenyl-benzotriazoles C-FRA Porcine circovirus type 2 epigallocatechin gallate heparan sulfate antiviral effect virus attachment microvirin lectin human immunodeficiency virus hepatitis C virus antiviral inhibitor non-immunogenic viral entry protein drugs LUMS1 oleanane-type derivatives influenza A virus (IAV) virus entry inhibitors hemagglutinin (HA) |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557448703321 |
Adamson Catherine | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Cellular and Molecular Mechanisms of Nephropathic Cystinosis |
Autore | Levtchenko Elena N |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (230 p.) |
Soggetto topico |
Medicine
Pharmacology |
Soggetto non controllato |
cystinosis
cysteamine bone osteoclast genotype CD34+ hematopoietic stem and progenitor cells gene therapy pre-clinical studies investigational new drug application clinical trial disulfiram mice zebrafish fertility azoospermia hypogonadism histopathology mouse model lysosomal storage disease cell and animal models infantile nephropathic cystinosis bone-muscle wasting fibroblast growth factor 23 osteoclasts sclerostin leptin fractures nephropathic cystinosis hollow fiber membrane 3-dimensional models autophagy macrophages inflammasome proximal tubular cells endocytosis apoptosis chitotriosidase interleukins galectin-3 novel therapies endolysosome epithelial cell differentiation homeostasis lysosomal storage diseases mitochondrial distress kidney proximal tubule programmed cell death central nervous system cortical atrophy arterial spin labelling cystine blood level lysosomal storage disorder history treatment strategies for cystinosis newborn screening clinical course CTNS-pathogenic variants newborn screening for cystinosis kidney progenitors cell model biomarkers cystine kidney therapeutic monitoring |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910585941103321 |
Levtchenko Elena N | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Lymphocytes in MS and EAE: More than just a CD4+ World |
Autore | Manu Rangachari |
Pubbl/distr/stampa | Frontiers Media SA, 2017 |
Descrizione fisica | 1 electronic resource (160 p.) |
Collana | Frontiers Research Topics |
Soggetto non controllato |
B cell
MAIT cell experimental autoimmune encephalomyelitis autoimmunity multiple sclerosis NK cell gamma-delta T cell CD8+ T cell central nervous system |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Lymphocytes in MS and EAE |
Record Nr. | UNINA-9910261139303321 |
Manu Rangachari | ||
Frontiers Media SA, 2017 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Magnesium in the central nervous system / / edited by Robert Vink, Mihai Nechifor [[electronic resource]] |
Autore | Vink Robert |
Pubbl/distr/stampa | University of Adelaide Press, 2011 |
Descrizione fisica | 1 online resource (viii, 342 pages) : digital, PDF file(s) |
Disciplina | 616.8 |
Soggetto topico |
Central nervous system - Diseases
Magnesium - Physiology Neurophysiology |
Soggetto non controllato |
magnesium
central nervous system neurological disease psychiatric disease Magnesium |
ISBN | 0-9870730-5-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Magnesium in Normal Brain -- Free magnesium concentration in human brain / Stefano Iotti and Emil Malucelli -- Intracellular magnesium homeostasis / Andrea M.P. Romani -- Magnesium transport across the blood-brain barriers / Mounir N. Ghabriel and Robert Vink -- Intracellular free Mg2+ and MgATP2- in coordinate control of protein synthesis and cell proliferation / Harry Rubin -- Magnesium and the Yin-Yang interplay in apoptosis / Valentina Trapani, Lucia Mastrototaro and Federica I. Wolf -- Brain magnesium homeostasis as a target for reducing cognitive ageing / Jean-Marie Billard -- Magnesium in Neurological Diseases -- The role of magnesium therapy in learning and memory / Michael R. Hoane -- The role of magnesium in headache and migraine / Lisa A. Yablon and Alexander Mauskop -- Magnesium in edema and blood-brain barrier disruption / Mehmet Kaya and Bulent Ahishali -- Magnesium and hearing loss / Isabelle Sendowski, Xavier Holy, Florent Raffin and Yves Cazals -- The role of magnesium in pain / Hyo-Seok Na, Jung-Hee Ryu and Sang-Hwan Do -- The role of magnesium in traumatic CNS injury / Naomi L. Cook, Frances Corrigan and Corinna van den Heuvel -- The use of magnesium in experimental cerebral ischaemia / Bruno P. Meloni, Kym Campbell and Neville W. Knuckey -- Magnesium in subarachnoid hemorrhage / Walter M. van den Bergh -- Magnesium in clinical stroke / Jeffrey L. Saver and Sidney Starkman -- Magnesium in cancer: more questions than answers / Marzia Leidi, Federica I. Wolf and Jeanette A.M. Maier -- Magnesium in Parkinson's disease: an update in clinical and basic aspects / Kiyomitsu Oyanagi and Tomoyo Hashimoto -- Involvement of Magnesium in Psychiatric Diseases -- Magnesium and Alzheimer's disease / Dehua Chui, Zheng Chen, Jia Yu, Honglin Zhang, Weishan Want, Yuetao Song, Huan Yang and Yi Liu -- Magnesium and stress / Magdalena D. Cuciureanu and Robert Vink -- Magnesium in neuroses / Victoria Papadopol and Mihai Nechifor -- Magnesium, hyperactivity and autism in children / Marianne Mousain-Bosc, Christian Siatka and Jean-Pierre Bali -- Magnesium in psychoses (schizophrenia, bipolar disorder) / Mihai Nechifor -- Magnesium and major depression / George A. Eby, III, Karen L. Eby and Harald Murck -- Magnesium in drug abuse and addiction / Mihai Nechifor. |
Record Nr. | UNINA-9910133684403321 |
Vink Robert | ||
University of Adelaide Press, 2011 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Matrix Metalloproteinase |
Autore | Ågren Magnus S |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (262 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
hemagglutinin-B
transwell co-cultures matrix metalloproteinases TNF-α matrix metalloproteinase peritoneal mesothelial cell gastric cancer metastatic dissemination MT4-MMP cancer diseases aggrecan aggrecanase ADAMTS cartilage arthritis MMP-2 MMP-9 inhibitor allodynia caspase-3 neuropathic pain dorsal root ganglion spinal nerve ligation tuberculosis tuberculous meningitis HIV-TB-associated IRIS extracellular matrix breakdown adult pediatric lung central nervous system matrix-metalloproteinase monocytes inflammation phagocytosis apoptosis blood sampling anticoagulants high-molecular-weight heparin IL-16 sICAM-1 IL-8 T cells a disintegrin and metalloproteinase EMMPRIN CD147 ectodomain shedding MMPs PTMs glycosylation phosphorylation glycosaminoglycans interleukin IL-6 IL-11 trans-signaling metalloproteases ADAM MMP meprin matrix metalloproteinases (MMPs) protease signaling invasion chemokine cytokine proteomics interferon Agkistrodon venom metalloproteinase fibrinogen antithrombotic metabolomics extracellular matrix cytokines proteinases interstitial collagens wound healing |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557717203321 |
Ågren Magnus S | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Mitochondria-targeted drug delivery |
Autore | Kopecka Joanna |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (290 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
retinal ischemia
blood-brain barrier endothelial reactive oxygen species oxidative stress tunneling nanotubules neuron central nervous system inflammation hypoxia anticancer peptide (ACP) antimicrobial peptide (AMP) anticancer peptides antimicrobial peptides host defense peptides prediction random forest mitochondria mitochondrial DNA mitochondrial disorders pharmacological therapy gene therapy precision medicine cardiovascular disease drug delivery mitochondria dysfunctions nanocarriers oxoglutarate carrier malate-aspartate shuttle cancer metabolism ATP production diphenyleneiodonium NADPH-oxidase differentiation proliferation mitochondria-targeted antioxidants LPS mitochondrial ROS antitumor agents fluorescence lifetime imaging medicinal chemistry metabolic drug mitochondrial carrier melanoma plumbagin cytotoxic effect metabolism cholesterol lipid raft mitochondrial permeability transition pore alkylphospholipid analog edelfosine mitochondrial oncometabolites cancer drug resistance mitochondrial disease heteroplasmy mitochondrial gene delivery |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910576881503321 |
Kopecka Joanna | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Nanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease: From Bench to Bedside |
Autore | Tagit Oya |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (296 p.) |
Soggetto topico |
Technology: general issues
History of engineering & technology Materials science |
Soggetto non controllato |
poly(lactic-co-glycolic acid) (PLGA)
blood–brain barrier (BBB) current Good Manufacturing Practice (cGMP) Food and Drug Administration (FDA) nanotechnology PLGA nanoparticles neurodegenerative diseases drug delivery central nervous system neuroprotective drugs fluorescent labeling DiI coumarin 6 rhodamine 123 Cy5.5 quantum yield brightness stability of fluorescent label confocal microscopy intracellular internalization in vivo neuroimaging double-emulsion method dry powder inhalation antigen release porous PLGA particles microfluidics methotrexate chitosan PLA/PLGA sustained release micro-implant animal model minimally invasive drug delivery system nanoparticles poly (lactic-co-glycolic acid) (PLGA) microfluidic pharmacokinetics (PK) and biodistribution atorvastatin calcium poly(lactide-co-glycolide) polymeric nanoparticles carrageenan induced inflammation anti-inflammatory radiolabeled nanoparticles nuclear medicine photothermal therapy phthalocyanine SKOVip-kat Katushka TurboFP635 JO-4 PLGA orthotopic tumors 3D culture spheroids poly(lactic-co-glycolic acid) nanomedicine scale-up manufacturing clinical translation inline sonication tangential flow filtration lyophilization downstream processing H. pylori design of experiments poly(lactic-co-glycolic) acid size cancer chemoimmunotherapy immunogenic cell death immune checkpoint blockade PNA5 glycopeptide mas receptor angiotensin PLGA diblock copolymer ester and acid-end capped double emulsion solvent evaporation biocompatible biodegradable cardiovascular nanoparticle solid-state characterization in vitro drug release kinetics modeling PEGylation amine emulsion polyvinyl alcohol (PVA) Pluronic triblock copolymer trehalose sucrose Indomethacin solvents stabilizers morphology particle-size encapsulation drug release cytotoxicity |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Nanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease |
Record Nr. | UNINA-9910580215803321 |
Tagit Oya | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Neuro-Immune Connections to Enable Repair in CNS Disorders |
Autore | Vanmierlo Tim |
Pubbl/distr/stampa | Frontiers Media SA, 2020 |
Descrizione fisica | 1 electronic resource (243 p.) |
Soggetto topico |
Medicine
Immunology |
Soggetto non controllato |
neuroimmunology
central nervous system immune system CNS repair CNS disorders |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557772003321 |
Vanmierlo Tim | ||
Frontiers Media SA, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Neutrophil Extracellular Traps : Mechanisms and Role in Health and Disease |
Autore | Anders Hans-Joachim |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (212 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
head-and-neck cancer
metastasis neutrophils NETs NETosis innate immunity G-CSF neutrophils extracellular traps ophthalmology diseases neutrophil extracellular traps (NETs) Alzheimer's disease multiple sclerosis ischemic stroke meningitis central nervous system brain neurons brain-blood barrier equine recurrent uveitis horse cathelicidin neutrophil extracellular traps Candida albicans quorum sensing farnesol cerebrospinal fluid adults children infection chemokines cytokines borrelia virus hemozoin plasma fibrinogen platelet malaria NLRP3 inflammasome IL-1β cardiovascular disease inflammation diabetes obesity liver injury neutrophil extracellular trap myeloperoxidase carbon tetrachloride autoimmunity autoimmune diseases autoantigens SARS-CoV-2 coronavirus complement thrombosis MERS-CoV necroinflammation periodontitis neutrophil functions |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Neutrophil Extracellular Traps |
Record Nr. | UNINA-9910557283903321 |
Anders Hans-Joachim | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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