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Cellular Senescence in Health, Disease and Aging: Blessing or Curse?
| Cellular Senescence in Health, Disease and Aging: Blessing or Curse? |
| Autore | Riessland Markus |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (112 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
AIM2 inflammasome
Alzheimer's disease amyotrophic lateral sclerosis biology of aging brain cancer cell-cycle cellular senescence chemotherapy resistance DNA damage geroscience homeostasis inflammation melanoma mild cognitive impairment n/a neurodegeneration neuronal senescence pancreatic adenocarcinoma POP3 post-mitotic prostate regeneration secreted protein acidic and rich in cysteine senescence senescence-associated secretory phenotype (SASP) senolytics stress response tauopathy tumor infiltration γH2AX |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cellular Senescence in Health, Disease and Aging |
| Record Nr. | UNINA-9910557382703321 |
Riessland Markus
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Centenarians-A Model to Study the Molecular Basis of Lifespan and Healthspan
| Centenarians-A Model to Study the Molecular Basis of Lifespan and Healthspan |
| Autore | Puca Annibale |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (204 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
ageing
aging aging-related disease allergy alternative therapy apoptosis C. elegans cellular senescence centenarians composition of royal jelly defective mitosis Di (2-Ethylhexyl) pthalate dietary interventions DNA methylation DNA-damage response elderly epigenetic clocks exosomes food allergy functional enrichment analysis glutathione gut healthspan healthy aging Hericium erinaceus hypersensitivity IGF-1 immunosenescence inflammation ingenuity pathway analysis lamin B1 lifespan longevity meniere's disease miRNA-mRNA networks mitochondrial respiratory complexes n/a nematode neurodegenerative diseases olive oil oxidative stress Parkinson's disease pathogen protection polyphenols probiotic bacteria redoxomics royal jelly serum telomere length vitagenes β-Dystroglycan |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557783503321 |
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Puca Annibale
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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DNA Replication Stress / Robert M. Brosh
| DNA Replication Stress / Robert M. Brosh |
| Autore | Brosh Robert M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
Werner Syndrome
A549 cells epigenetic neurodegeneration Genome integrity adaptation cellular senescence genome instability Werner Syndrome Protein lipofuscin cell cycle checkpoints exonuclease 1 template-switching energy metabolism mutation frequency DNA replication fork regression motor neuron disease Microsatellites Alzheimer's disease chromatin remodeler repair of DNA damage AP site analogue mutagens replication timing Thermococcus eurythermalis nucleolar stress gene expression mutations spectra origin firing Fanconi Anemia superfamily 2 ATPase DNA translocation DNA repair SSB signaling homologous recombination common fragile sites 8-chloro-adenosine replication genome stability mutagenicity fork reversal multiple sclerosis non-B DNA protein stability heterogeneity ubiquitin SenTraGorTM (GL13) replication restart EdU ?-arrestin NER aging SSB end resection oxidative stress ATR dormant origins R loops DNA damage response Difficult-to-Replicate Sequences DNA double-strand repair endonuclease IV ALS double strand break repair premature aging replication stress EXO1 POL? translesion synthesis strand displacements G2-arrest DNA replication pattern SSB repair genome integrity G protein-coupled receptor kinase interacting protein 2 (GIT2) MMR replicative stress senolytics spacer interactome ATR-Chk1 DDR pathway C9orf72 replication fork restart translesion DNA synthesis DNA damage mismatch repair DNA replication stress DNA helicase Polymerase kappa DNA fiber assay H1299 cells TLS APE2 ageing cell death chromosome TopBP1 barley clock proteins post-translational modification 8-oxoG S phase ataxia telangiectasia mutated (ATM) G protein-coupled receptor (GPCR) Polymerase eta cancer G protein-coupled receptor kinase (GRK) helicase genomic instability Parkinson's disease nucleotide excision repair SupF |
| ISBN |
9783039213900
3039213903 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367564903321 |
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Brosh Robert M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Retina in Health and Disease
| The Retina in Health and Disease |
| Autore | Ptito Maurice |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (465 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
3,5-DHBA
Ac2-26 African-American age-related macular degeneration AII amacrine cell altricial bird species Alzheimer's disease AMD amyloid angiogenesis angiography antioxidants apoptosis arterioles astrocytes ATP atypical cannabinoid receptors autophagy axon betulinic acid bioenergetics biomarker black catalase CD4+CD25+ cellular senescence Charles Bonnet syndrome clinical trials cognitive decline complement cascade complication development diabetes diabetes mellitus diabetic retinopathy dLGN Drp1 early detection eccentricity EEG electron microscopy electroretinography endoplasmic reticulum epidermal growth factor exendin-4 experimental models eye eye inflammation fingolimod FPR receptor functional analysis gap junction germ-free mice GFAP glucagon-like peptide-1 GPR81 growth cone GRP78 gut microbiome gut-retina axis HCAR1 HDAC high-fat diet histone deacetylase hyperglycemia hypoxia immunodeficient RCS rat immunohistochemistry inflammation inflammatory mediators iPSC iPSC-RPE ischemia-reperfusion injury kallikrein-kinin system kinin receptors lactate LED screen light damage lipopolysaccharide macroglia mesenchymal stem cells metabolism microglia microglia morphotype microvascular microvascular complications and dysfunction mitochondria monkeys motor protein Müller cells multiple sclerosis myosin 1C n/a natural bioactive extracts neurod neurodegeneration neuroprotection neurovascular unit Notch ON/OFF asymmetry optic nerve crush optic neuritis optical coherence tomography optical filter osteopontin outer segments oxidative stress parvalbumin photoreceptor photoreceptors precocial bird species progenitor cell programmed cell death Prox1 reactive oxygen species regeneration remodeling respiration resting state retina retinal degeneration retinal degenerative diseases retinal detachment retinal fluorescence imaging retinal ganglion cells retinal glial cell retinal inflammation retinal light injury retinal microglia retinal pigment epithelium retinal protection retinal transplantation retinal vessels retinogenesis retinopathy rhodopsin RNA sequencing senescence-associated galactosidase activity signal transducer and activator of transcription 3 spinal cord injury stem cell therapy stress response systemic disease trichostatin A (TSA) typical cannabinoid receptors ultrathin parylene unfolded protein response vascular endothelial growth factor (VEGF) vascularization visual function visual hallucination visual system zebrafish |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557336603321 |
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Ptito Maurice
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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