Aging and Age-Related Disorders : : From Molecular Mechanisms To Therapies / / Vladimir Titorenko
| Aging and Age-Related Disorders : : From Molecular Mechanisms To Therapies / / Vladimir Titorenko |
| Autore | Titorenko Vladimir |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (322 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
advanced glycated end products
microRNAs differentiation transcription skin absorption cellular quiescence lifespan longevity genes protein kinases self-renewal circadian blood-brain barrier aging-related disorders sirtuin-1 inflammation arterial aging reactive oxygen species electron microscopy reconstructed human skin rejuvenation low-dose fluvastatin and valsartan combination inflammaging hematopoietic stem cell aging cell cycle mitochondria ribose the nervous system nanomedicine proteostasis adult stem cells immunosenescence cell signaling mechanisms of quiescence maintenance metabolism aging melatonin diabetes mechanisms of quiescence entry and exit Drosophila melanogaster GSK3 (glycogen synthase kinase 3) |
| ISBN |
9783039213566
3039213563 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367567903321 |
Titorenko Vladimir
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products : Volume 2
| Antitumoral Properties of Natural Products : Volume 2 |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (300 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
13-ethylberberine
Akt AKT anthraquinones anti-cancer anti-cancer activity anti-cancer agents anti-tumor activity anticancer Antioxidant activities antioxidants antioxidation antiproliferation agents Antiproliferative antiproliferative activity antitumoral activity antrodin C apoptosis AR Artemisia absinthium ASE Aspergillus fumigatus ATM-Chk2 autophagic flux inhibition autophagy bee venom betulinic acid Brazilian Cerrado biome cancer cancer stem cells capsazepine carrageenan Catalpa speciosa Celastraceae cell cycle arrest cell proliferation cell signaling cephalotaxine cervical cancer Cheiloclinium cognatum chemotherapeutic adjuvant chemotherapy chiral resolution CIP2A CLE-10 CLEFMA Colocasia esculenta colorectal cancer cells copper Cordyceps sinensis coronarin D CrataBL cryptolepine Cucurbitacin B cytotoxic activity cytotoxicity Dendrobium officinale diallyl disulfide dicentrine DLD-1 cells doxorubicin drug resistance ECD calculation EGFR endoplasmic reticulum stress entrapment efficiency Euphorbia tirucalli FAK/S6K1 flavonoids folk medicine food bioactive FOXO1 fruit Ganoderma tsugae gastric cancer gastric cancer cells gefitinib-resistant NSCLC Gene expression glioblastoma glioblastoma multiforme glioma glucose uptake glycosyltransferase grape leaves human neuroblastoma cells IL-6/JAK2/STAT3 inflammation inflammatory diseases ingenol invasion isochromanes isocryptolepine JNK lactoferrin hydrolysate LC3 lichen Licochalcone A lipogenesis lung adenocarcinoma lysosomal degradation lysosomal membrane permeabilization Magnolia acuminata manganese MAPK MCF-7 cells MDA-MB-231 melanoma melittin mesenchymal stem cells metabolic stability metastasis microenvironment migration mitochondrial membrane potential mitochondrial ROS mitochondrial-dependent pathway molecular mechanism mTOR multiple myeloma n/a naringenin natural compounds natural product alkaloids natural products natural yellow Monascus pigments NCI-60 cancer cell line necrotic neferine neocryptolepine NF-κB no-toxicity Nutraceuticals oncogene osteosarcoma p38 patuletin phenols phloretin phytochemicals PI3K/AKT/mTOR PI3K/Akt/mTOR pathway plant lectin plant-derived foods plantation mode Plenckia populnea porphyran preclinical tests pristimerin pro-apoptotic effects proanthocyanins prostate cancer protease inhibitor protein kinase C protein synthesis inhibition Pulsatilla saponin D quality control quercetagetin quercetin ROS RT-R breast cancer cells Salacia crassifolia Salacia elliptica SB365 seaweed secondary metabolites semi-synthetic derivative SREBP-1 stable nanocapsules stemness potential structure activity relationships structure elucidation tarin Taxus cuspidata temozolomide TNF-α TP traditional preparation transcriptional regulation triterpenoids TRPV1 tumidulin ursolic acid vegetable water-soluble zerumbone Zeylenone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Antitumoral Properties of Natural Products |
| Record Nr. | UNINA-9910557531303321 |
Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products
| Antitumoral Properties of Natural Products |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (344 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
13-ethylberberine
Akt AKT anthraquinones anti-cancer anti-cancer activity anti-cancer agents anti-tumor activity anticancer Antioxidant activities antioxidants antioxidation antiproliferation agents Antiproliferative antiproliferative activity antitumoral activity antrodin C apoptosis AR Artemisia absinthium ASE Aspergillus fumigatus ATM-Chk2 autophagic flux inhibition autophagy bee venom betulinic acid Brazilian Cerrado biome cancer cancer stem cells capsazepine carrageenan Catalpa speciosa Celastraceae cell cycle arrest cell proliferation cell signaling cephalotaxine cervical cancer Cheiloclinium cognatum chemotherapeutic adjuvant chemotherapy chiral resolution CIP2A CLE-10 CLEFMA Colocasia esculenta colorectal cancer cells copper Cordyceps sinensis coronarin D CrataBL cryptolepine Cucurbitacin B cytotoxic activity cytotoxicity Dendrobium officinale diallyl disulfide dicentrine DLD-1 cells doxorubicin drug resistance ECD calculation EGFR endoplasmic reticulum stress entrapment efficiency Euphorbia tirucalli FAK/S6K1 flavonoids folk medicine food bioactive FOXO1 fruit Ganoderma tsugae gastric cancer gastric cancer cells gefitinib-resistant NSCLC Gene expression glioblastoma glioblastoma multiforme glioma glucose uptake glycosyltransferase grape leaves human neuroblastoma cells IL-6/JAK2/STAT3 inflammation inflammatory diseases ingenol invasion isochromanes isocryptolepine JNK lactoferrin hydrolysate LC3 lichen Licochalcone A lipogenesis lung adenocarcinoma lysosomal degradation lysosomal membrane permeabilization Magnolia acuminata manganese MAPK MCF-7 cells MDA-MB-231 melanoma melittin mesenchymal stem cells metabolic stability metastasis microenvironment migration mitochondrial membrane potential mitochondrial ROS mitochondrial-dependent pathway molecular mechanism mTOR multiple myeloma n/a naringenin natural compounds natural product alkaloids natural products natural yellow Monascus pigments NCI-60 cancer cell line necrotic neferine neocryptolepine NF-κB no-toxicity Nutraceuticals oncogene osteosarcoma p38 patuletin phenols phloretin phytochemicals PI3K/AKT/mTOR PI3K/Akt/mTOR pathway plant lectin plant-derived foods plantation mode Plenckia populnea porphyran preclinical tests pristimerin pro-apoptotic effects proanthocyanins prostate cancer protease inhibitor protein kinase C protein synthesis inhibition Pulsatilla saponin D quality control quercetagetin quercetin ROS RT-R breast cancer cells Salacia crassifolia Salacia elliptica SB365 seaweed secondary metabolites semi-synthetic derivative SREBP-1 stable nanocapsules stemness potential structure activity relationships structure elucidation tarin Taxus cuspidata temozolomide TNF-α TP traditional preparation transcriptional regulation triterpenoids TRPV1 tumidulin ursolic acid vegetable water-soluble zerumbone Zeylenone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557419703321 |
Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Nanomedicine
| Cancer Nanomedicine |
| Autore | Hoskins Clare |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (510 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
actin
active targeting acute toxicity adsorption albumin albumin nanoparticle albumin nanoparticles anacardic acid angiogenesis anti-cancer anti-metastatic enzyme cancer therapy anti-topoisomerase activity anti-tumor immunity antibody drug conjugate (ADC) anticancer and antibacterial activity antitumor strategy apoptosis ascorbic acid BALB-neuT mice biodistribution biomimetic biomimetic core-shell nanoparticles biomimicry bleeding blood brain barrier brain tumours breast cancer cabazitaxel cancer cancer diagnosis cancer nanomedicine cancer therapy cathepsin D cathepsin L cats cell signaling cellular interaction cellular microenvironment chemico-physical functionalization chemotherapeutics chirality separation clinical status clinical translation collagen colloidal stability colorectal carcinoma combinatorial therapy copper CPMV CSCs cyclodextrins cytotoxicity diagnostics differentiated neuroblastoma dioleoylphosphatidylethanolamine DNA origami docetaxel dogs DOX doxorubicin drug combination drug delivery drug delivery system drug-gene delivery drug-in-cyclodextrin-in-liposome dual-targeting epithelial-to-mesenchymal transition EPR effect erlotinib everolimus exosomes extracellular vesicles FA-DABA-SMA flow folate folate receptor folic receptor alpha glioblastoma glioma gold nanoparticles gold nanorods graphene oxide hepatocellular carcinoma hyaluronic acid hyaluronidase hybrid nanoparticles hyperthermia hyperthermia therapy hypoxia imaging immune modulation immunosuppression immunotherapy Immunotherapy in situ vaccine in vitro in vitro anti-cancer activity integrin intra-arterial chemotherapy intracellular disruption intracranial glioma iron affinity lanthanide metal ligand lipid nanoparticles liposome liposomes loading lung cancer lymphadenectomy magnetic actuation magnetic drug targeting magnetic hyperthermia magnetic nanoparticles magnetic nanowires magnetic silica-coated iron oxide nanochains magnetometer mammary carcinoma mangiferin MDA-MB-231 melanoma membrane-wrapped mesenchymal stem cells (MSCs) Mesoporous silica nanoparticle mesoporous silica nanoparticles metabolism microbubble microfluidic mitoxantrone mixed micelle molecular imaging monoclonal antibodies multicellular tumor spheroids nano-bio interactions nano-engineered MSCs nanobiotechnology nanocarrier nanomedicine nanomedicines nanomicelles nanoparticle nanoparticles nanostructured lipid carrier nanosystems nanotechnology: bioengineering nanotherapeutics NASH near IR hyperspectral imaging NK cell-derived exosomes oncogenes oncogenic proteins organoids organotin orthotopic lung tumor model osteopontin ovarian cancer ovarian carcinomatosis oxidation-sensitive release paclitaxel pancreatic cancer parvifloron D passive targeting PD-L1 PEGylation peptidomimetics pH responsive photodynamic therapy photodynamic therapy article photothermal therapy photothermal treatment plasmonic photothermal therapy plasmonics platelet membrane PLGA poly(hydroxyethyl acrylate-co-allyl methyl sulfide) copolymer polydopamine nanoparticles polymeric nanoconstruct polymeric nanoparticles prostate cancer radiotherapy real-time quantitative polymerase chain reaction (qPCR) remote loading RGD peptide riboflavin secondary structure self-assembly sentinel lymph node dissection shear stress single-walled carbon nanotubes siRNA size SN38 spheroids SPION stimuli-responsive superparamagnetic iron oxide nanoparticles surgery target treatment targeted delivery targeted delivery system targeted drug delivery targeted therapy TAT peptide temoporfin theranostic nanomaterials theranostics therapeutics titanate nanotubes translational medicine triple negative breast cancer tumor microenvironment tumor spheroid disruption tumor targeting tumor vectorization tumour microenvironment tumour targeting ultrasound vectorization VEGF verteporfin viral nanoparticles vitamin B2 VX2 tumor Vδ2 T cells yet reasonably common within the subject discipline zoledronic acid β-cyclodextrin nanosponges |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557114703321 |
Hoskins Clare
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Lo trovi qui: Univ. Federico II | ||
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Emerging Mechanisms in Neuronal Signaling: from Cell Biology to Pathogenesis
| Emerging Mechanisms in Neuronal Signaling: from Cell Biology to Pathogenesis |
| Autore | Eduardo Guido Mario |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (454 p.) |
| Soggetto topico |
Neurosciences
Science: general issues |
| Soggetto non controllato |
cell signaling
developmental disorders lipid signaling metabolism neurodegeneration oxidative stress retina transcription factors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Emerging Mechanisms in Neuronal Signaling |
| Record Nr. | UNINA-9910557394703321 |
Eduardo Guido Mario
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| Frontiers Media SA, 2020 | ||
| Lo trovi qui: Univ. Federico II | ||
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Emerging Role of Lipids in Metabolism and Disease
| Emerging Role of Lipids in Metabolism and Disease |
| Autore | Pallottini Valentina |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (308 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
acid sphingomyelinase
adiponectin adipose tissue angiogenesis atherosclerosis ATM autotaxin BDNF BET proteins brain breast cancer breast reconstruction cardiovascular disease cell proliferation cell signaling cholesterol Cholesterol chronic inflammation diabetes mellitus DNA damage response double strand breaks eicosanoids endothelial cell epicardial fat thickness epigenetics epinephrine fatty acid Fatty acids female frontal cortex G-protein coupled receptors gender glyceride haptoglobin high-cholesterol diet high-density lipoprotein high-sensitivity c-reactive protein hippocampus HMGCR hyperglycemia ionizing radiation ischemia ischemic stroke JQ1 LDLr leptin lipid lipid droplets lipid mediators Lipid mediators lipid metabolism lipid metabolism diseases lipid storage diseases Lipids lipocalin lipolysis lipophagy Lipophagy lipoproteins liver lysocardiolipin acyltransferase lysophosphatidic acid metabolic reprogramming metabolic stress metabolism mTORC1 mutations neutral sphingomyelinase nuclear sphingolipids oral drug absorption oxidative stress oxidized phospholipids p53 pathology phosphatidylinositol 4,5-bisphosphate phospholipase A2 (PLA2) phospholipase C phospholipase D phospholipid polyunsaturated fatty acids prodrug prostaglandins pulmonary fibrosis radiation SOD sphingolipids Sphingolipids sphingomyelin metabolism sphingosine kinase 1 sphingosine-1-phosphate SREBP steroid synaptic proteins TFEB TMEM97 visceral fat thickness |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557800303321 |
Pallottini Valentina
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Lo trovi qui: Univ. Federico II | ||
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Impaired Mitochondrial Bioenergetics under Pathological Conditions
| Impaired Mitochondrial Bioenergetics under Pathological Conditions |
| Autore | Lenaz Giorgio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (460 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research & information: general |
| Soggetto non controllato |
aging
aging heart assembly factor ATP synthase ATP synthase/hydrolase atypical myopathy Barth syndrome Bcl-2 family bioenergetics C cancer cardiolipin cardiomyopathy cell culture cell signaling cellular bioenergetics cellular signaling complex I assembly complex I deficiency complex I structure complex III COVID-19 cristae cytochrome b diabetes Dilated Cardiomyopathy with Ataxia electron transport chain energy metabolism entorhinal cortex equine primary myoblasts exercise fatty acid oxidation fibroblasts frozen tissue G mutation glucagon heart failure high-resolution respirometry human disease immune system influenza innate immune response insulin Leigh syndrome leukocytes lipoxidation-derived damage m.3243A> m.8909T> mammalian complex I mathematical model MAVS MDA5 metabolic disease mitochondria mitochondrial disease mitochondrial diseases mitochondrial DNA mitochondrial dynamic mitochondrial dynamics mitochondrial dysfunction mitochondrial permeability transition pore mitochondrial proteostasis MT-ATP6 MTCYB mutations n/a NADH dehydrogenase nephropathy neurodegeneration oleate oxidative damage oxidative phosphorylation oxidative stress oxygen consumption palmitate pancreatic endocrine cells pet mutants platelets programmed cell death protein import respiratory chain respiratory complex assembly respiratory complexes respiratory supercomplexes respirometry RIG-I ROS RSV Saccharomyces cerevisiae SARS CoV-2 Sengers syndrome skeletal muscle supercomplexes supernumerary subunits toxicity assays viral infections yeast |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585934503321 |
Lenaz Giorgio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Lo trovi qui: Univ. Federico II | ||
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Mechanisms of Adiponectin Action / Tania Fiaschi
| Mechanisms of Adiponectin Action / Tania Fiaschi |
| Autore | Fiaschi Tania |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (222 p.) |
| Soggetto non controllato |
acidic and rich in cysteine (SPARC)
regeneration fertility pig endocrine cancer NGF? reproductive tract neuritogenesis skeletal muscle matricellular proteins adiponectin isoforms obesity atherosclerosis hair growth-related factor ovarian cancer adipose tissue AdipoRon extracellular signal-regulated kinase (ERK) PC12 cells endometrial cancer AMPK metabolism adiponectin transcriptome exercise training inflammation BIAcore muscle adipokines human follicular dermal papilla cell estrogen receptor endometrium adiponectin inducer breast cancer implantation microarray Secreted protein adipogenesis kojyl cinnamate ester derivative cell signaling lipotoxicity cervix cancer cancer cholesterol efflux myopathies diabetes |
| ISBN |
9783039212460
303921246X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910673903503321 |
Fiaschi Tania
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Lo trovi qui: Univ. Federico II | ||
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mTOR in Human Diseases / Olivier Dormond
| mTOR in Human Diseases / Olivier Dormond |
| Autore | Dormond Olivier |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
primary cilia
neurodegeneration nutrient sensor PI3K transcriptomics phosphorylation metabolic reprogramming autophagy Alzheimer's disease rapalogs liver angiogenesis mTOR complex MBSCs advanced biliary tract cancers Medulloblastoma epithelial to mesenchymal transition AMPK p70S6K lipid metabolism thyroid cancer sodium iodide symporter (NIS)/SLC5A5 male fertility anesthesia illumina mTOR inhibitor miRNA Hutchinson-Gilford progeria syndrome (HGPS) eIFs Emery-Dreifuss muscular dystrophy (EDMD) glucose AKT oral cavity squamous cell carcinoma (OSCC) glucose and lipid metabolism cellular signaling aging tumor microenvironment rapamycin leukemia chloral hydrate rapalogues schizophrenia T-cell acute lymphoblastic leukemia senescence lamin A/C neurotoxicity neurodevelopment inhibitor methamphetamine pulmonary fibrosis mTOR mTOR inhibitors combination therapy proteolysis fluid shear stress tumour cachexia biomarkers synapse gluconeogenesis mTOR signal pathway Sertoli cells immunosenescence miRNome protein aggregation senolytics metabolism NGS mTORC2 mTORC1 metabolic diseases IonTorrent apoptosis dopamine receptor nocodazole microenvironment everolimus acute myeloid leukemia immunotherapy spermatogenesis bone remodeling signalling targeted therapy ageing therapy NVP-BEZ235 fructose physical activity laminopathies MC3T3-E1 cells cell signaling microRNA cancer lipolysis melatonin Parkinson's disease |
| ISBN |
9783039210619
3039210610 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346684303321 |
Dormond Olivier
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Lo trovi qui: Univ. Federico II | ||
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New Trends on Vanadium Chemistry, Biochemistry, and Medicinal Chemistry
| New Trends on Vanadium Chemistry, Biochemistry, and Medicinal Chemistry |
| Autore | Gambino Dinorah |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Research & information: general
Chemistry Inorganic chemistry |
| Soggetto non controllato |
polyoxometalates
decavanadate cytotoxicity insulin-like activity diabetes therapy vanadium biochemistry vanadium speciation vanadium proteins DNA fluorescence binding constants mechanism of action oxidovanadium(V) vanadium Schiff base coordination complex low acute toxicity Oxidovanadium(V) Schiff base X-ray crystallography DNA interaction 2-aminopyrimidinium experimental and theoretical characterization DFT docking RNA/DNA vitamin E EPR tocopherol 51V NMR urethane aerosol delivery lung cancer apoptosis antineoplastic oxidovanadium(IV) phenantrholine chrysin vanadium cellular uptake anticancer albumin interaction glycosylated flavonoid oxidovanadium(IV) complex antitumoral antioxidant cell signaling cancer anticancer agents |
| ISBN | 3-0365-5765-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910637783803321 |
Gambino Dinorah
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Lo trovi qui: Univ. Federico II | ||
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