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Anticancer Inhibitors
| Anticancer Inhibitors |
| Autore | Fantacuzzi Marialuigia |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (216 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
breast cancer
tamoxifen LY294002 synergism apoptosis cell cycle tea (Camellia sinensis) flowers BTFS A2780/CP70 ovarian cancer cells S phase cell cycle arrest nicotinamide phosphoribosyltransferase NAD+ biosynthesis inhibitor azacyclohexane anticancer drug drug design enthalpy effect NSCLC Cathepsin K cell proliferation cell migration cell invasion mTOR isatin-hydrazones cytotoxicity CDK2 inhibitor ATP competitive inhibitor ADME analysis receptor tyrosine kinases protein-protein interactions protein engineering directed evolution angiogenesis binding affinity agonistic activity saponins phytochemicals tea (Camellia sinensis) flower ovarian cancer autophagy ZMYND8 tumorigenesis epigenetic regulation pro-oncogenic effects tumor suppression tacrine-coumarin derivatives DNA topoisomerases I, II lung carcinoma cells A549 chemotherapy prodrug drug targeting overexpressed enzymes ADC ADEPT GDEPT LEAPT PROTAC cyclin-dependent kinase cancer resistance small molecule inhibitors PROTACs statins pancreatic cancer DNA microarray pitavastatin cerivastatin simvastatin fluvastatin atorvastatin pravastatin HMG-CoA reductase inhibitors |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069203321 |
Fantacuzzi Marialuigia
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Foodborne Pathogens and Food Safety
| Foodborne Pathogens and Food Safety |
| Autore | Lourenco Antonio Afonso |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (254 p.) |
| Soggetto topico |
Biology, life sciences
Microbiology (non-medical) Research & information: general |
| Soggetto non controllato |
AcrD
amidase ampicillin antibiotic resistance antimicrobial blue light aqueous chlorine dioxide arugula Bacillus cereus group bacteriophage benzalkonium chloride bionanoparticles BNPs Campylobacter enumeration cell invasion chemical interventions chicken chromogenic media detection egg white endogenous photosensitizers endolysin enterohemorrhagic Escherichia coli enteroids food handling food hygiene food safety food-borne bacteria food-borne salmonellosis foodborne bacteria foodborne illness foodborne pathogen gene expression growth potential iceberg lettuce in vitro cell models invasion genes bacterial virulence Listeria monocytogenes Listeria spp malic acid microbial contamination milk alternatives monitoring multi-drug resistance multidrug-resistant bacteria organoids panC sequencing pathogenic bacteria pathogenic mechanism performance testing porphyrins poultry bio-mapping prevalence quantitative microbial risk assessment ready-to-eat rocket rucola Salmonella Salmonella Enteritidis Salmonella enumeration Salmonella Typhimurium salmonellosis Salmonellosis shelf-life smear spinach stress resistance stress response sublethal antimicrobial exposure survival thymol toxin gene profiling virulence whole papaya yogurt |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580206503321 |
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Lourenco Antonio Afonso
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers
| Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers |
| Autore | Kutner Andrzej |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (450 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
1,2,4-triazole
25 vitamin D 24-hydroxylase A-ring active substance delivery systems active substance-controlled release ADME alkaloids alpha-ketoglutarate analogue actions at genes anti-depressant therapy anti-inflammatory activity anticancer activity anticancer drug anticancer drugs antidepressants antimalarial antimicrobial activity antimicrobial compounds antimicrobial peptide (AMP) antioxidant activity antiparasitic agents antiviral proteins apoptosis Au(III) complex biomarker biomedical hydrogels calcilytic calcimimetic calcium-sensing receptor cancer cancer cells cancer therapy cancer treatment CD-ring cell cycle cell invasion cell migration Chelidonium majus ChIP-chip analysis colon cancer colorectal cancer copper (II) complexes CRISPR/Cas9 cyclooxygenase CYP24A1 CYP24A1-dependent metabolism CYP27B1 cytotoxic activity cytotoxic study cytotoxicity defense-related proteins depression dermaseptin distal enhancers drug drug design drug design and discovery drug discovery dual 5-HT1A/SERT activity electrochemistry enantiomer fluorine frog skin peptides genistein genome editing glucose metabolism glycoconjugates gold gold electrode greater celandine hemolysis high-grade serous ovarian cancer cells histone deacetylase (HDAC) histone H3 acetylation HT-29 human DNA topoisomerase hydrogels for cosmetology hydrogels for dermatology IL-8 inflammation JNK latex LHRH lung cancer major latex protein MALDI metabolite metallodrugs methotrexate molecular docking molecular modeling multimodal activity n/a nanoparticles organometallic oxidation mechanisms Phyllomedusa bicolor Plasmodium falciparum (P. falciparum) PRI-2191 proliferation prostate cancer proteome analysis pyridazinone pyrido[1,2-c]pyrimidines resveratrol rickets RNA polymerase II SAR self-assembled monolayer side-chain spectroscopic data split luciferase-based biosensor stereospecificity synthesis targeted therapy tetrahydro-β-carbolines TGF-β therapeutic peptides thiourea transcription transdermal active substance delivery systems VEGF vitamin D vitamin D analogs vitamin D biology and action vitamin D hormone (1,25(OH)2D3) vitamin D receptor vitamin D3 Warburg effect |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585938903321 |
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Kutner Andrzej
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Redox-Active Molecules as Therapeutic Agents
| Redox-Active Molecules as Therapeutic Agents |
| Autore | Fernandes Ana Sofia |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (266 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
(poly)phenols
adipose-derived mesenchymal stem cell amniotic membrane-derived mesenchymal stem cell antioxidant capacity antioxidants apoptosis apurinic/apyrimidinic endonuclease 1 assisted reproductive technology ATF4 BAPN bioactivity-based assays breast cancer cancer therapy cardiorenal syndrome carnosic acid CD IGS rats cell cycle cell invasion chemoresistance cisplatin conditioned medium curcumin cyanidin Cysteamine cytotoxicity DNA damage doxorubicin E3330 embryo EMT glutathione peroxidase glutathione reductase GSH H2S donors hydrogen sulfide hypercholesterolemia in vitro culture in vitro fertilization inhibitors invasion KEAP1 lactic acid bacteria lysyl-oxidase lysyl-oxidase like 2 metabolomics metastases migration mitochondrial reactive oxygen species N-acetyl cysteine n/a non-small cell lung cancer NRF2 nuclear factor erythroid 2-related factor 2 (Nrf2) oxidative stress OxPhos peroxiredoxin 3 pro-oxidant therapy prostate cancer reactive oxygen species redox signaling Rubus genus selenium-enriched Enterococcus faecium selenium-enriched Streptococcus thermophilus SGK1 sildenafil systemic sclerosis thiostrepton thiosulfate verbascoside withanolide yeast-based discovery platform |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213403321 |
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Fernandes Ana Sofia
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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