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Drug Metabolism/Transport and Pharmacokinetics
| Drug Metabolism/Transport and Pharmacokinetics |
| Autore | Song Im-Sook |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (232 p.) |
| Soggetto topico |
Manufacturing industries
Medicine and Nursing |
| Soggetto non controllato |
acute renal failure
anti-obesity agent automatization BCRP biliary excretion breast cancer resistance protein Caco-2 carboxylesterase Carthamus tinctorius extract catalposide celecoxib cisplatin comparative pharmacokinetic study compatibility mechanism compound K creatinine clearance CYP3A4 cytochrome P450 cytochrome P450 enzymes diabetes dose-dependent pharmacokinetics drug absorption drug dosing drug interaction drug transporter drug-drug interaction DWP16001 efflux transporter EpiIntestinal first-pass fluorescence food-drug interactions gentamicin head-and-neck cancer healthy Korean subjects hepatic and intestinal first-pass effect hepatic CYP3A1(23) HPLC HSG4112 human hepatocytes in vitro human metabolism influx transporter inhibition mode inhibitor intestinal metabolism kidney distribution kinetic analysis large volume direct injection mertansine metabolism metformin modeling nonrenal clearance notoginseng total saponins oral availability organic cation transporter 2 P-gp pharmacokinetics physiologically based pharmacokinetic model population pharmacokinetic prazosin protopanaxadiol (PPD) quercetin rats real-time measurements renal clearance renal excretion repaglinide sodium-glucose cotransporter 2 (SGLT2) inhibitors stereoselectivity sulfasalazine sulfotransferase taxanes tiropramide tissue engineering tofacitinib transporter-enzyme interplay UDP-glucuronosyltransferase UDP-glucuronosyltransferases UHPLC-MS/MS verapamil |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607703321 |
Song Im-Sook
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Osteoarthritis: From Molecular Pathways to Therapeutic Advances
| Osteoarthritis: From Molecular Pathways to Therapeutic Advances |
| Autore | Veronese Nicola |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (306 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
adipokines
aging angiogenesis autophagy biomarker cartilage cartilage trauma celecoxib cell death chemokines chondrocyte chondrocytes chondrocytic commitment chondroitin chondroprotection collagen cytokines dietary supplements early diagnosis ECM exercise glucosamine glucosamine sulfate hexosamine biosynthetic pathway hyaluronic acid hydrostatic pressure hypertrophy IFNγ, IL-17 IL-1β IL-4 inflammaging inflammation infrared spectroscopy inhibitor Interleukin-1β joint modelling linker modifications matrix metalloproteinases mechanical loading meniscus mesenchimal stem cells methylsulfonylmethane microRNA miRNAs mitochondrial dysfunction MMP-13 molecules MRM native tissue analysis near-infrared spectroscopy NF-κB NO synthase nutraceuticals O-GlcNAcylation obesity osteoarthritis osteochondral explant culture oxidative stress pathogenesis pharmacological assay physical activity post-traumatic osteoarthritis proteomics Raman spectroscopy regulation remodeling RNA-Seq sex as a biological variable SMAD2/3 signaling TGF-β therapy type II collagen vibrational spectroscopy visfatin vitamin C vitamin D whole transcriptome sequencing Wnt/β-catenin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Osteoarthritis |
| Record Nr. | UNINA-9910566461503321 |
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Veronese Nicola
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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