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Bayesian Design in Clinical Trials
| Bayesian Design in Clinical Trials |
| Autore | Berchialla Paola |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (190 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
dose-escalation
combination study modelling assumption interaction adaptive designs adaptive randomization Bayesian designs clinical trials predictive power target allocation Bayesian inference highest posterior density intervals normal approximation predictive analysis sample size determination bayesian meta-analysis clustering binary data priors frequentist validation Bayesian rare disease prior distribution meta-analysis sample size bridging studies distribution distance oncology phase I dose-finding dose–response bayesian inference prior elicitation latent dirichlet allocation clinical trial power-prior poor accrual Bayesian trial cisplatin doxorubicin oxaliplatin dose escalation PIPAC peritoneal carcinomatosis randomized controlled trial causal inference doubly robust estimation propensity score Bayesian monitoring futility rules interim analysis posterior and predictive probabilities stopping boundaries Bayesian trial design early phase dose finding treatment combinations optimal dose combination |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557608103321 |
Berchialla Paola
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Rocking qualitative social science : an irreverent guide to rigorous research / / Ashley T. Rubin
| Rocking qualitative social science : an irreverent guide to rigorous research / / Ashley T. Rubin |
| Autore | Rubin Ashley T. |
| Pubbl/distr/stampa | Stanford, California : , : Stanford University Press, , [2021] |
| Descrizione fisica | 1 online resource (304 pages) |
| Disciplina | 300.721 |
| Soggetto topico |
Social sciences - Research - Methodology
Qualitative research |
| Soggetto non controllato |
archival/historical methods
causal inference content analysis data analysis data collection ethnographic and interview methods qualitative methods research design research questions social science research |
| ISBN | 1-5036-2824-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover -- Table of Contents -- Acknowledgments -- 1 Introduction to Dirtbagging -- 2 Topo: What Exactly Are Qualitative Methods? -- 3 Picking Your Proj: Identifying Your Research Question -- 4 On Belay: Connecting Your Work to an Anchor -- 5 Mapping out the Route: How and When Research Design Matters -- 6 Starting on the Right Foot: Making and Justifying Your Case Selection -- 7 Flaking out the Rope: How to Check Your Sample -- 8 Bivvy Time: The Fieldwork Model of Data Collection -- 9 The Crux: Content Analysis, Analytic Memos, and Other Tricks -- 10 Placing Pro: Making Causal Claims with Qualitative Data -- 11 Living on the Sharp End: Dealing with Skeptics of Qualitative Research -- 12 The Sweeper -- Notes -- Bibliography -- Index. |
| Record Nr. | UNINA-9910794558303321 |
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Rubin Ashley T.
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| Stanford, California : , : Stanford University Press, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Rocking qualitative social science : an irreverent guide to rigorous research / / Ashley T. Rubin
| Rocking qualitative social science : an irreverent guide to rigorous research / / Ashley T. Rubin |
| Autore | Rubin Ashley T. |
| Pubbl/distr/stampa | Stanford, California : , : Stanford University Press, , [2021] |
| Descrizione fisica | 1 online resource (304 pages) |
| Disciplina | 300.721 |
| Soggetto topico |
Social sciences - Research - Methodology
Qualitative research |
| Soggetto non controllato |
archival/historical methods
causal inference content analysis data analysis data collection ethnographic and interview methods qualitative methods research design research questions social science research |
| ISBN | 1-5036-2824-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover -- Table of Contents -- Acknowledgments -- 1 Introduction to Dirtbagging -- 2 Topo: What Exactly Are Qualitative Methods? -- 3 Picking Your Proj: Identifying Your Research Question -- 4 On Belay: Connecting Your Work to an Anchor -- 5 Mapping out the Route: How and When Research Design Matters -- 6 Starting on the Right Foot: Making and Justifying Your Case Selection -- 7 Flaking out the Rope: How to Check Your Sample -- 8 Bivvy Time: The Fieldwork Model of Data Collection -- 9 The Crux: Content Analysis, Analytic Memos, and Other Tricks -- 10 Placing Pro: Making Causal Claims with Qualitative Data -- 11 Living on the Sharp End: Dealing with Skeptics of Qualitative Research -- 12 The Sweeper -- Notes -- Bibliography -- Index. |
| Record Nr. | UNINA-9910818338403321 |
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Rubin Ashley T.
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| Stanford, California : , : Stanford University Press, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Systems Analytics and Integration of Big Omics Data
| Systems Analytics and Integration of Big Omics Data |
| Autore | Hardiman Gary |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto non controllato |
precision medicine informatics
drug sensitivity chromatin modification cell lines biocuration neurodegeneration multivariate analysis artificial intelligence epigenetics missing data sequencing clinical data class imbalance integrative analytics algorithm development for network integration deep phenotype non-omics data feature selection Gene Ontology miRNA-gene expression networks omics data plot visualization Alzheimer's disease tissue classification epidemiological data proteomic analysis genotype RNA expression indirect effect multi-omics dementia multiomics integration data integration phenomics network topology analysis challenges transcriptome enrichment analysis regulatory genomics scalability heterogeneous data systemic lupus erythematosus database microtubule-associated protein tau disease variants genomics joint modeling distance correlation annotation phenotype direct effect curse of dimensionality gene-environment interactions logic forest machine learning KEGG pathways multivariate causal mediation amyloid-beta bioinformatics pipelines support vector machine pharmacogenomics candidate genes tissue-specific expressed genes cognitive impairment causal inference |
| ISBN | 3-03928-745-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404089603321 |
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Hardiman Gary
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation
| Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation |
| Autore | Ciccodicola Alfredo |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (356 p.) |
| Soggetto non controllato |
transcription factor
transcription self-incompatibility cytogenetics epigenetics selenocysteine tea AP-2? nonsense-mediated decay transcriptomics Akt1 promoter cell metabolism pediveliger larvae Patau Syndrome tristetraprolin (TTP) long non-coding RNA (lncRNA) pregnancy G-quadruplex glioblastoma placenta PRDM gene family circRNA-disease associations bioadhesive gene expression Crassostrea gigas transcription regulation cell differentiation RNA interference transcriptome inflammatory response FOXO1 Adiponectin liquid chromatograph-tandem mass spectrometer (LC-MS/MS) selenium selenocysteine insertion sequence inflammation selenoproteins research methods nutritional status structures and functions CRISPR/Cas9 fertilization melanin differentially expressed genes tyrosinase posttranscriptional regulation major depressive disorder human malignancies pathway CDKN1C transcription factors p57Kip2 enhancer activity mouse disorders high-throughput RNA sequencing (RNA-Seq) TCGA data analysis RNA-seq heterogeneous network insect and drug design therapeutic targets mechanisms obesity Pacific oyster Rsh regulon common pathway Pax3 somatic mutations nutrition molecular docking bioinformatics interactome long non-coding RNAs transcriptional regulation Pteria penguin (Röding Adiponectin receptors transcriptome profiling 1798) N-acyl-l-homoserine lactone ppGpp tumorigenesis sphingomonads human disease adenosine and uridine-rich elements (AREs) progress and prospects miR-25-3p acute leukemia Novosphingobium pentaromativorans US6-1 microscopy cancer molecular pathways causal inference |
| ISBN | 3-03921-266-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Transcriptional Regulation |
| Record Nr. | UNINA-9910346689003321 |
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Ciccodicola Alfredo
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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