Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (594 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
thymidylate synthase
cytotoxicity 1,2,3-triazole 1,3,4-oxadiazole 5-fluoruracil pemetrexed docking 3,4'-bis-guanidino 3-amino-4'-guanidino diphenyl ether phenyl pyridyl ether intramolecular hydrogen bond cancer cell viability HL-60 BRAF apoptosis thieno[2,3-d][1,2,3]triazine acetamide H1299 HER2 EGFR Bcl-2 inhibitors Indole-based analogues benzimidazole MTT cytotoxic assay cell cycle analysis DNA fragmentation ELISA solid/lipid nanoparticles phenstatin letrozole tubulin polymerisation inhibitor aromatase inhibitor breast cancer hybrid molecule dual-targeting molecule designed multiple ligand NaMSA cyclophosphamide histopathology testis urinary bladder anticancer agents enantioselective synthesis gastric adenocarcinoma tryptophanol concentration-guided dosing model informed dosing physiologically based pharmacokinetics sorafenib tyrosil-DNA-phosphodiesterase 1 adamantane resin acid TDP1 cytotoxic agents apoptosis induction HT-29 cells MDA-MB-231 cells mechanism prediction STAT inhibitors miR-21 hydrazide derivatives nitrogen scaffolds mitoxantrone cardiotoxicity inflammation oxidative stress age cumulative dose Trk NTRK tissue-agnostic larotrectinib entrectinib Trk fusion protein kinase inhibitors USFDA cancer patent review generic product doxazosin MD simulations combretastatin A-4 cytotoxic activity hybrid compounds indazole mucin MUC1 MUC16 immunotherapy cancer vaccine CAR (chimeric antigen receptor) ADC (antibody-drug conjugate) thiourea interleukin-6 trypan blue assay chalcones exportin-1 covalent binding CovDock anticancer activity xanthone in vitro in vivo isolation synthesis heterocyclic compound benzenesulfonamides imidazoles alkylated colony formation tumor spheroids HDAC inhibitors chalcone dual inhibitors carvedilol kidney toxicity 7-deaza-4'-thioadenosine derivatives multi-kinase inhibitor anticancer nucleoside Imiquimod drug efflux multidrug resistance Toll-Like Receptor |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
Meegan Mary J
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Creatine Supplementation for Health and Clinical Diseases
| Creatine Supplementation for Health and Clinical Diseases |
| Autore | Kreider Richard B |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (562 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
ergogenic aids
cellular metabolism phosphagens sarcopenia cognition diabetes creatine synthesis deficiencies concussion traumatic brain injury spinal cord injury muscle atrophy rehabilitation pregnancy immunity anti-inflammatory antioxidant anticancer creatine nutritional supplements fertility newborn development brain injury post-viral fatigue syndrome chronic fatigue syndrome GAA creatine kinase dietary supplements exercise skeletal muscle glycemic control type 2 diabetes mellitus phosphorylcreatine dietary supplement ergogenic aid youth athletes osteoporosis osteosarcopenia frailty cachexia innate immunity adaptive immunity inflammation macrophage polarization cytotoxic T cells toll-like receptors vascular pathology cardiovascular disease oxidative stress vascular health female menstrual cycle hormones exercise performance menopause mood children height BMI-for-age stature-for-age growth phosphocreatine creatine transporter supplementation treatment heart heart failure ischemia myocardial infarction anthracycline cardiac toxicity energy metabolism cell survival bioinformatics systems biology cellular allostasis dynamic biosensor pleiotropic effects of creatine (Cr) supplementation inflammatory bowel diseases (IBD) ulcerative colitis Crohn’s disease creatine kinase (CK) phosphocreatine (PCr) creatine transporter (CrT) intestinal epithelial cell protection intestinal tissue protection creatine perfusion organ transplantation Adenosine mono-phosphate (AMP) activated protein kinase (AMPK) liver kinase B1 (LKB1) mitochondrial permeability transition pore (mPTP) reactive oxygen species (ROS) glucose transporter (GLUT) T cell antitumor immunity metabolic regulator cancer immunotherapy supplements muscle damage recovery immobilization atrophy muscular dystrophy amyotrophic lateral sclerosis Parkinson’s Disease cardiopulmonary disease mitochondrial cytopathy hypertrophy athletic performance weightlifting resistance exercise training muscular power muscular adaptation muscle fatigue adipose tissue muscle strength physiological adaptation mitochondria thermogenesis MAP kinase signaling system sodium-chloride-dependent neurotransmitter symporters signal transduction intradialytic creatine supplementation hemodialysis muscle protein energy wasting clinical trial muscle weakness chronic fatigue cognitive impairment depression anemia resistance training sports nutrition strength toxicity methylation hyperhomocysteinemia neuromodulation MCDA mitochondriopathia cardiac infarction long COVID hypoxia stroke neurodegenerative diseases noncommunicable disease adenosine 5′-monopnophosphate-activated protein kinase anthracyclines creatine supplementation cardiac signaling cardiotoxicity doxorubicin soy vegetarian/vegan diet amino acids dietary ingredients performance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566476003321 |
|
Kreider Richard B
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Emerging Challenges of Cardiovascular and Metabolic Dysfunctions in Cardio-oncology: From Bench to Bedside
| Emerging Challenges of Cardiovascular and Metabolic Dysfunctions in Cardio-oncology: From Bench to Bedside |
| Autore | Nebigil Canan G |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (127 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
cardiooncology
cardiotoxicity antracyclines biomarkers GPCR (G protein coupled receptors) epigenetics (methylation/demethylation) HPSC-cardiomyocytes HDLP |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Emerging Challenges of Cardiovascular and Metabolic Dysfunctions in Cardio-oncology |
| Record Nr. | UNINA-9910557230403321 |
|
Nebigil Canan G
|
||
| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Immunotherapy, Tumor Microenvironment and Survival Signaling
| Immunotherapy, Tumor Microenvironment and Survival Signaling |
| Autore | Golubovskaya Vita |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (376 p.) |
| Soggetto topico |
Medicine
Clinical & internal medicine |
| Soggetto non controllato |
Autophagy
colorectal cancer immunotherapy tumor stroma tumor microenvironment immune checkpoint inhibitors chemotherapy tyrosine kinase inhibitors angiogenesis check point inhibitors programmed cell death protein 1 programmed cell death 1 ligand 1 cardiotoxicity lung metastasis CAR-T hypoxia tumor microenvironment CD19 BCMA cancer melanoma immune escape antigen loss chimeric antigen receptor electroporation lentivirus lentiviral transduction macrophages leukemia cells lytic peptides targeted therapy dendritic cells pathogenesis risk factors breast cancer resistance checkpoint targeted treatment personalized medicine pediatric solid tumors chimeric antigen receptors cancer vaccines oncolytic viral therapy immunomodulation DCLK1 tumor stem cells clonogenicity mitochondria mitochondrial transfer tunneling nanotubes triple-negative breast cancer immune checkpoint inhibitor combination therapy cancer nanomedicine tumor antigens cancer metabolism cancer immunotherapy nanoparticles immunotherapeutic agent immunomodulators tuft cells cancer stem cells immunotherapies myeloid-derived suppressor cells regulatory T cells crosstalk tumor immune evasion cell-cell contact β2 integrins CD18 CD11 CAR-T cells CD37 cell therapy tumor antigen lymphoma CAR macrophage CAR T cell solid tumors immunometabolism miRNA immunogenic cell death |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580205403321 |
|
Golubovskaya Vita
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Ischemic Heart Disease in the Context of Different Comorbidities
| Ischemic Heart Disease in the Context of Different Comorbidities |
| Autore | Costache Irina-Iuliana |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (242 p.) |
| Soggetto topico |
Medicine
Cardiovascular medicine |
| Soggetto non controllato |
coronary artery disease
ischemic heart disease atherosclerosis genetic risk factors heritability polymorphism GWAS PRS COVID-19 myocardial ischemia electrocardiography accelerated atherosclerosis coronary spasm coronary thrombosis endothelial dysfunction cancer prevention radiotherapy chemotherapy liver cirrhosis prevalence liver transplantation treatment myocardial injury cytokines biomarkers heart failure left ventricular remodeling myocardial infarction wall stress inflammation neurohormonal activation inflammatory bowel disease ulcerative colitis Crohn's disease cardiovascular risk frailty chronic coronary syndrome elderly acute coronary syndrome carbon monoxide poisoning severity of poisoning cardiotoxicity troponin cardiac dysfunction non-alcoholic fatty liver disease liver-heart axis |
| ISBN | 3-0365-5809-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910637784603321 |
|
Costache Irina-Iuliana
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
New Prognostic and Predictive Markers in Cancer Progression
| New Prognostic and Predictive Markers in Cancer Progression |
| Autore | Costantini Susan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (294 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
MSI2
OSCC oral cancer musashi 2 prognosis N-cadherin EMT breast cancer new metastasis eribulin blood biomarker bladder cancer immune checkpoint inhibitor CD8+ T effector cells microRNA biomarkers head and neck cancer laryngeal cancer prediction metastasis lifestyle habit chemo-/radio resistance therapeutic target AKT AR castration-resistant prostate cancer (CRPC) MAPK mTOR PI3K prostate cancer therapeutic resistance WNT miRNA melanoma melanoma resistance to MAPK/MEK inhibitors resistance to immune checkpoint inhibitors TNBC BRCA1/2 HRR PDL1 TILs PI3KCA PTEN CTCs CSC pancreatic cancer K-RAS oncogene oncogene dependency targeted therapies genomic mutations transcriptomics metabolomics selenoproteins cancer HUB nodes major histocompatibility complex (MHC) human leukocyte antigen (HLA) antigen processing machinery (APM) molecules carcinogenesis tumor predisposition cancer immunotherapy pheochromocytoma paraganglioma head and neck neoplasms head and neck tumors genetic syndromes mutations hyperglycemia cardioncology nivolumab cytokines cardiotoxicity acetyltransferase cancer prognosis NAA10 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557794803321 |
|
Costantini Susan
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Physiological and Pathological Role of ROS: Benefits and Limitations of Antioxidant Treatment
| Physiological and Pathological Role of ROS: Benefits and Limitations of Antioxidant Treatment |
| Autore | Di Meo Sergio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (236 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
CTCL
apoptosis cell viability c-FLIP XIAP artemisinin SH-SY5Y cells hippocampal neurons H2O2 AMPK pathway atherosclerosis sphingomyelin synthase 2 endothelial dysfunction endoplasmic reticulum stress β-catenin insulin resistance cancer cardiovascular disease neurodegenerative disorders exercise mitochondria oxidative stress PGC-1 Nrf2 UCPs ROS light DNA damage evolution D-box cavefish Spalax trimethylamine N-oxide cardiomyocytes cardiotoxicity mitochondrial membrane potential CORM-2 NADPH oxidase AP-1 HO-1 Renal cell carcinoma (RCC) reactive oxygen species (ROS) glutathione (GSH) metabolism cancer therapy clear cell RCC papillary RCC chromophobe RCC sarcopenia reactive oxygen species redox signaling antioxidant supplementation protein aggregation redox proteinopathy peroxiredoxins tumorigenesis ROS scavengers |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Physiological and Pathological Role of ROS |
| Record Nr. | UNINA-9910557430503321 |
|
Di Meo Sergio
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||