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Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
| Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing |
| Autore | Kim Jong Heon |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
nanoparticles
fungi drug delivery systems marine biological synthesis myconanotechnology canesten clotrimazole vulvovaginal vaginitis mycosis candidosis yeast infection candida candida albicans vaginal health anticandidal activity indazole pyrazole 3-phenyl-1H-indazole drug design acetylsalicylic acid (ASA, aspirin) capsule CAP64 Cryptococcus membrane potential (ΔΨM) photodynamic treatment photosensitiser ultrastructure drug repurposing antifungals repositioning yeasts emerging fungi multidrug resistance therapeutic alternatives new targets Candida auris Aspergillus spp antifungal beta-glucan polycations Galleria mellonella model retinoids Candida spp onychomycosis Malassezia spp dermatophytes microbiology mycology all-trans retinoic acid Acanthamoeba free-living ameba Acanthamoeba keratitis isavuconazonium sulfate cyst drug drug discovery drug targets invasive aspergillosis treatment invasive fungal infections fission yeast cell wall β(1,3)-D-glucan synthase antifungal drugs echinocandin drugs echinocandin resistance Fks resistance hot spots cytokinesis septation cell separation cell integrity cell lysis sporotrichosis Felis catus quinones hydrazones zoonoses host-directed drug therapy azoles polyenes echinocandins viral infections azole synergy resistance Candida natural products |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Advances in Antifungal Development |
| Record Nr. | UNINA-9910585935503321 |
Kim Jong Heon
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bacterial Meningitis : Epidemiology and Vaccination
| Bacterial Meningitis : Epidemiology and Vaccination |
| Autore | Stuart James M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
meningitis
child mortality neonatal sepsis global health global health estimates modelling Streptococcus pneumoniae Haemophilus influenzae Neisseria meningitidis bacterial meningitis S. pneumoniae N. meningitidis H. influenzae S. agalactiae conjugate vaccines post-vaccine surveillance vaccine Africa mathematical modelling susceptibility invasive bacterial infections complement genetic factors Streptococcus agalactiae group B streptococci capsule meningococcal group nongroupable meningococcal carriage invasive meningococcal disease meningococcal urethritis neonatal infections epidemiology antibiotic resistance etiologic diagnosis enterovirus group B Streptococcus neurological sequelae hearing loss seizure epilepsy hydrocephalus focal neurological deficit corticosteroid dexamethasone invasive pneumococcal disease pneumococcal conjugate vaccines serotypes vaccine impact pneumococcal meningitis serotype distribution PCV impact global meta-analysis surveillance meningococcus pneumococcus Hib group B streptococcus conjugate vaccine rapid diagnostic test national reference laboratory cerebrospinal fluid Niger Burkina Faso tuberculosis tuberculous meningitis TBM children impact of Hib conjugate vaccine Hia NTHi burden social and economic costs WHO meningitis roadmap disability |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Bacterial Meningitis |
| Record Nr. | UNINA-9910557626103321 |
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Stuart James M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Hurdles for Phage Therapy (PT) to Become a Reality
| Hurdles for Phage Therapy (PT) to Become a Reality |
| Autore | Brüssow Harald |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (484 p.) |
| Soggetto non controllato |
alginate
abortive infection bacterial resistance bacteriophages ATMP MALDI-MS adaptation Bacteriophage horizontal gene transfer adaptive immunity co-evolution Listeria ivanovii personalised medicines pH stability phage-human host interaction vB_SauM-fRuSau02 antimicrobial resistance phagodisinfection biofilm capsule depolymerase animal model phage cocktails Enterococcus cases report zoonosis resistance magistral formula experimental therapy Belgium phage therapy E. faecalis nontraditional antibacterial industrial phage application Democratic Republic of the Congo OrthoMCL Germany high-throughput sequencing antimicrobial infection antibiotic therapy Kayvirus phages Twortlikevirus bacterial disease human host Pseudomonas aeruginosa phage multidrug-resistant bacteria bacterial infection Salmonella Typhi rhamnopolysaccharide compassionate use crop production compounding pharmacy antimicrobial resistance (AMR) best practices bacteriophage efficacy phage sensitivity antibiotic-resistance antibiotic lysins PTMP Escherichia coli typhoid fever patent landscape phage preparation innate immunity anti-phage antibodies immunology Staphylococcus aureus global health clinical trial adsorption Brussels phage-resistance Galleria mellonella science communication history of science virus-host interactions foodborne illness prophage resistance management biofilms IND immunomodulation frequency of resistance capsule gastrointestinal tract phage-host interactions disinfection production bacteriophage therapy bacteriophage Staphylococcus magistral preparation extended-spectrum beta lactamases (ESBL) Viral proteins antibiotic resistance genomics phage biocontrol therapy target selection viral genomes evolution pharmaceutical paradigm shift personalized medicine pharmaceutical legislation food safety regulation virulence developing countries infectious disease regulatory framework sustainable agriculture Klebsiella pneumoniae |
| ISBN | 3-03921-392-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Hurdles for Phage Therapy |
| Record Nr. | UNINA-9910367566603321 |
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Brüssow Harald
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Polyamine Metabolism in Disease and Polyamine-Targeted Therapies
| Polyamine Metabolism in Disease and Polyamine-Targeted Therapies |
| Autore | Murray-Stewart Tracy |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (240 p.) |
| Soggetto non controllato |
protein synthesis in cancer
neuroblastoma epigenetics Drosophila imaginal discs pneumococcal pneumonia transgenic mice spermidine/spermine N1-acetyl transferase ?-difluoromethylornithine MYC skeletal muscle protein expression curcumin colorectal cancer autophagy human embryonic kidney 293 (HEK293) melanoma tumor immunity Snyder-Robinson Syndrome Streptococcus pneumoniae B-lymphocytes autoimmunity spermine oxidase cell differentiation diferuloylmethane immunity antizyme transgenic mouse polyamine hirsutism chemoprevention CRISPR transglutaminase polyamine analogs NF-?B spermine synthase atrophy aging oxidative stress mast cells African sleeping sickness pancreatic ductal adenocarcinoma eflornithine carcinogenesis ornithine decarboxylase polyamine transport inhibitor putrescine neutrophils spermidine untranslated region spermine polyphenol M2 macrophages polyamine transport system metabolism difluoromethylorthinine DFMO antizyme inhibitors capsule polyamine transport eosinophils MCF-7 cells difluoromethylornithine polyamine metabolism mutant BRAF polyamines cadaverine proteomics airway smooth muscle cells breast cancer X-linked intellectual disability complementation T-lymphocytes bis(ethyl)polyamine analogs antizyme 1 cancer osteosarcoma |
| ISBN | 3-03921-153-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367757003321 |
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Murray-Stewart Tracy
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Very High Resolution (VHR) Satellite Imagery: Processing and Applications
| Very High Resolution (VHR) Satellite Imagery: Processing and Applications |
| Autore | Marcello Javier |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (262 p.) |
| Soggetto non controllato |
very high-resolution Pléiades imagery
surface convergence data augmentation acquisition geometry SVM classification urban water mapping beaver dam analogue agriculture parcel segmentation morphological building index airborne hypespectral imagery sunglint correction water index over-segmentation index (OSI) High-resolution satellite imagery multi-resolution segmentation (MRS) GaoFen-2 (GF-2) benthic mapping scene classification greenhouse extraction edge constraint Deformable CNN built-up areas extraction ultra-dense connection seagrass beaver mimicry forested mountain natural hazards remote sensing dimensionality reduction techniques road extraction landslide monitoring Slumgullion landslide synthetic aperture radar building detection Worldview-2 saliency index under-segmentation index (USI) texture analysis fast marching method video satellite CNN capsule super-resolution feature distillation shadow detection PrimaryCaps semiautomatic compensation unit superpixels riparian QuickBird submesoscale linear unmixing accuracy assessment composite error index (CEI) cyanobacteria local feature points Faster R-CNN occluded object detection error index of total area (ETA) large displacements threshold stability remote sensing imagery water column correction canopy height model spiral eddy sub-pixel offset tracking consensus stream restoration western Baltic Sea Worldview very high-resolution image CapsNet atmospheric correction |
| ISBN | 3-03921-757-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Very High Resolution |
| Record Nr. | UNINA-9910367747503321 |
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Marcello Javier
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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