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Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor
| Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor |
| Autore | Holzmann Klaus |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (276 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adenocarcinoma of the esophagogastric junction
AKT anticancer astrocytoma autocrine signaling autophagy brain cancer breast cancer cancer cancer signaling cancer-associated fibroblasts coreceptor ERK ERK1/2 estrogen FGF FGF-mediated signaling FGF18 FGF19 FGF2 FGF8 FGFR FGFR1 FGFR2 FGFR2c FGFR4 fibroblast growth factor fibroblast growth factor receptors FRS2 gastric cancer gene regulation GPER HCC HEK293 immunohistochemistry infigratinib sensitivity inhibitors JNK1 keratinocyte kinase inhibitor LY2874455 malignant glioma malignant pleural mesothelioma melanoma membrane proteins monoclonal antibody MTOR n/a negative feedback loop neoadjuvant therapy neurite outgrowth NVP-BGJ398 optogenetics overall survival PC12 phosphorylation prognosis receptor cross-talk receptor kinase resistance review sarcoma seborrheic keratosis serine signaling skin small molecule Sprouty proteins squamous and basal cell carcinoma structure targeted therapy tumor promoter tumor suppressor |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Fibroblast Growth Factor Receptor |
| Record Nr. | UNINA-9910557898903321 |
Holzmann Klaus
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges
| Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges |
| Autore | Gabazza Esteban C |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (348 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
acute lung injury
anaplastic lymphoma kinase angiogenesis antitumor efficacy apoptosis bleomycin breast cancer butylidenephthalide cancer cancer-associated fibroblasts cancer-associated fibroblasts (CAFs) carcinogenesis cirrhosis clinical symptoms common pathways crizotinib cystic formation cytokine cytokines DHA diagnosis EMT Erk1/2 extracellular matrix fibrosis genetic instability GPR120 GPR40 growth factor HBV HCV hepatic stellate cells hepatic stellate cells (HSCs) hepatocellular carcinoma hepatocellular carcinoma (HCC) hepatocytes heterogeneity Hippo pathway idiopathic pulmonary fibrosis idiopathic pulmonary fibrosis (IPF) immunohistochemistry inflammation interstitial fluid pressure leiomyoma leiomyosarcoma lipopolysaccharide lncRNA lung cancer lung cancer (LC) marker mechanotransduction metabolic reprogramming metastasis miRNA myometrium n/a nanoparticles non-alcoholic steatohepatitis non-small cell lung cancer (NSCLC) omega-3 fatty acid pathogenesis pathology pathophysiology protein S pulmonary fibrosis reactive oxygen species regeneration renal injury signal pathway SMAD smooth muscle tumor of uncertain malignant potential SOX2 SREBP-1 targeted therapy TAZ TGF-? therapy transforming growth factor-? tumor tumor microenvironment tumor necrosis factor ? tumor stiffness type I collagen uterine fibroid Wnt YAP |
| ISBN | 3-03921-707-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Links between Fibrogenesis and Cancer |
| Record Nr. | UNINA-9910367745903321 |
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Gabazza Esteban C
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Precision Medicine in Solid Tumors
| Precision Medicine in Solid Tumors |
| Autore | Dey Nandini |
| Descrizione fisica | 1 online resource (304 p.) |
| Soggetto topico |
Medicine and Nursing
Oncology |
| Soggetto non controllato |
adjuvant chemotherapy
anaplastic lymphoma receptor tyrosine kinase breast cancer cancer cancer-associated fibroblasts cfDNA chemotherapy circulating free DNA clinical guideline clonality classification comprehensive genomic profiling CTC ctDNA DDR genes Decision tree digital enrichment driver mutation EGFR mutation EGFR-TKI electronic records epidermal growth factor receptor extent of resection gene panel sequencing glioblastoma prognosis HNSCC immune checkpoint inhibitors immunocytochemistry immunotherapy intratumor heterogeneity laboratory-friendly liquid biopsy molecular barcoding molecular genotyping multiple biopsies n/a new drug development next-generation sequencing next-generation sequencing (NGS) NGS non-small cell lung cancer open data osimertinib outcome overall survival parallel double-detection PARP inhibitors PD-L1 pediatric tumors personalized precision oncology precision medicine presumed germline findings random forest regulatory reform resistance screening sequencing smoking solid cancer strategic therapeutic intervention targeted therapy tDNA thymoma TMB TNBC subtypes triple-negative breast cancer (TNBC) tumor evolution tumor mutational burden tumor profiling test tyrosine kinase inhibitor universal health-care system whole-exome sequencing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595078103321 |
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Dey Nandini
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| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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