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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (528 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
ABT-737
acetazolamide acetylcholine adjuvant therapy amoeboid motility angiogenesis apoptosis arthralgia Bcl-2 family BCL2L10 biomarkers BRAF BRAF inhibitor BRAF inhibitors BRAF-mutant melanoma cancer cancer associated fibroblast cancer stem cells carbonic anhydrase cell therapy checkpoint inhibitor cholinergic system combined therapy ctDNA CXCL10 cyclopamine cytokines cytotoxicity diagnosis DOCK4 drug resistance essential oils exosomes extracellular vesicles FAK hedgehog HIPPO HuR immunity immunotherapy interferon invasion ipilimumab lactate dehydrogenase lipid metabolism liquid biopsy liver-directed-therapies machine learning MANS peptide MARCKS mechanism of action melanoma melanoma immune infiltrate melanoma markers melanoma metastasis melanoma PDX melanomagenesis metalloproteinases metastases metastasis metastatic dormancy metastatic therapy metastatic uveal melanoma (mUM) microenvironment microRNAs MITF ML258 motility mucosal melanoma muscarinic receptors n/a nanoparticles nicotinic receptors nivolumab OXPHOS patient stratification PD-1 pembrolizumab phosphorylation plasmacytoid dendritic cells prediction principal component analysis prognosis prognostication protein tyrosine phosphatase PTPs inhibitors Rac1 radiotherapy resistance rheumatoid arthritis sex-hormones sex/gender ShcD adaptor protein siRNA slow cycling phenotype small molecules SOCE STAT3 Support Vector Machine survival target therapy targeted therapy targeted-therapy therapeutic resistance therapy TLR TPC2 tumor microenvironment tumour microenvironment uveal melanoma (UM) WNT5A |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Alterations of epigenetics and microRNAs in cancer and cancer stem cell [[electronic resource] /] / topic editor: Yoshimasa Saito
| Alterations of epigenetics and microRNAs in cancer and cancer stem cell [[electronic resource] /] / topic editor: Yoshimasa Saito |
| Autore | Yoshimasa Saito |
| Pubbl/distr/stampa | Frontiers Media SA, 2014 |
| Descrizione fisica | 1 online resource (79 pages) : illustrations; digital, PDF file(s) |
| Disciplina | 616.99 |
| Collana |
Frontiers in research topics
Frontiers in genetics |
| Soggetto topico |
Epigenetics
Stem cells Genetics Cancer - Treatment - Research |
| Soggetto non controllato |
MicroRNAs
cancer stem cells Methylation epigenetics Cancer |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Alterations of epigenetics and microRNAs in cancer and cancer stem cell / Yoshimasa Saito -- Culturing intestinal stem cells: applications for colorectal cancer research / Masayuki Fuji and Toshiro Sato -- Characterizing the Retinoblastoma 1 locus: putative elements for Rb1 regulation by in silico analysis / Mohammadreza Hajjari, Atefeh Khoshnevisan and Bernardo Lemos -- Multilayer-omics analyses of human cancers: exploration of biomarkers and drug targets based on the activities of the International Human Epigenome Consortium / Yae Kanai and Eri Arai -- Non-coding RNAs as epigenetic regulator of glioma stem-like cell differentiation / Keisuke Katsushima and Yutaka Kondo -- Aberrantly methylated genes in human papillary thyroid cancer and their association with BRAF/RAS mutation / Yasuko Kikuchi, Eiichi Tsuji, Koichi Yagi, Keisuke Matsusaka, Shingo Tsuji, Junichi Kurebayashi, Toshihisa Ogawa, Hiroyuki Aburatani, Atsushi Kaneda -- MicroRNAs in Barrett's esophagus: future prospects / Juntaro Matsuzaki and Hidekazu Suzuki -- Epigenetic alteration and microRNA dysregulation in cancer / Hiromu Suzuki, Reo Maruyama, Eiichiro Yamamoto and Masahiro Kai -- The role of microRNAs in the regulation of cancer stem cells / Ryou-u Takahashi, Hiroaki Miyazaki and Takahiro Ochiya -- Disruption of the expression and function of microRNAs in lung cancer as a result of epigenetic changes / Kousuke Watanabe and Daiya Takai -- The role of mesenchymal stem cell in cancer development / Hiroshi Yagi and Yuko Kitagawa. |
| Record Nr. | UNINA-9910136405603321 |
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Yoshimasa Saito
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| Frontiers Media SA, 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products : Volume 2
| Antitumoral Properties of Natural Products : Volume 2 |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (300 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
13-ethylberberine
Akt AKT anthraquinones anti-cancer anti-cancer activity anti-cancer agents anti-tumor activity anticancer Antioxidant activities antioxidants antioxidation antiproliferation agents Antiproliferative antiproliferative activity antitumoral activity antrodin C apoptosis AR Artemisia absinthium ASE Aspergillus fumigatus ATM-Chk2 autophagic flux inhibition autophagy bee venom betulinic acid Brazilian Cerrado biome cancer cancer stem cells capsazepine carrageenan Catalpa speciosa Celastraceae cell cycle arrest cell proliferation cell signaling cephalotaxine cervical cancer Cheiloclinium cognatum chemotherapeutic adjuvant chemotherapy chiral resolution CIP2A CLE-10 CLEFMA Colocasia esculenta colorectal cancer cells copper Cordyceps sinensis coronarin D CrataBL cryptolepine Cucurbitacin B cytotoxic activity cytotoxicity Dendrobium officinale diallyl disulfide dicentrine DLD-1 cells doxorubicin drug resistance ECD calculation EGFR endoplasmic reticulum stress entrapment efficiency Euphorbia tirucalli FAK/S6K1 flavonoids folk medicine food bioactive FOXO1 fruit Ganoderma tsugae gastric cancer gastric cancer cells gefitinib-resistant NSCLC Gene expression glioblastoma glioblastoma multiforme glioma glucose uptake glycosyltransferase grape leaves human neuroblastoma cells IL-6/JAK2/STAT3 inflammation inflammatory diseases ingenol invasion isochromanes isocryptolepine JNK lactoferrin hydrolysate LC3 lichen Licochalcone A lipogenesis lung adenocarcinoma lysosomal degradation lysosomal membrane permeabilization Magnolia acuminata manganese MAPK MCF-7 cells MDA-MB-231 melanoma melittin mesenchymal stem cells metabolic stability metastasis microenvironment migration mitochondrial membrane potential mitochondrial ROS mitochondrial-dependent pathway molecular mechanism mTOR multiple myeloma n/a naringenin natural compounds natural product alkaloids natural products natural yellow Monascus pigments NCI-60 cancer cell line necrotic neferine neocryptolepine NF-κB no-toxicity Nutraceuticals oncogene osteosarcoma p38 patuletin phenols phloretin phytochemicals PI3K/AKT/mTOR PI3K/Akt/mTOR pathway plant lectin plant-derived foods plantation mode Plenckia populnea porphyran preclinical tests pristimerin pro-apoptotic effects proanthocyanins prostate cancer protease inhibitor protein kinase C protein synthesis inhibition Pulsatilla saponin D quality control quercetagetin quercetin ROS RT-R breast cancer cells Salacia crassifolia Salacia elliptica SB365 seaweed secondary metabolites semi-synthetic derivative SREBP-1 stable nanocapsules stemness potential structure activity relationships structure elucidation tarin Taxus cuspidata temozolomide TNF-α TP traditional preparation transcriptional regulation triterpenoids TRPV1 tumidulin ursolic acid vegetable water-soluble zerumbone Zeylenone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Antitumoral Properties of Natural Products |
| Record Nr. | UNINA-9910557531303321 |
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Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products
| Antitumoral Properties of Natural Products |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (344 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
13-ethylberberine
Akt AKT anthraquinones anti-cancer anti-cancer activity anti-cancer agents anti-tumor activity anticancer Antioxidant activities antioxidants antioxidation antiproliferation agents Antiproliferative antiproliferative activity antitumoral activity antrodin C apoptosis AR Artemisia absinthium ASE Aspergillus fumigatus ATM-Chk2 autophagic flux inhibition autophagy bee venom betulinic acid Brazilian Cerrado biome cancer cancer stem cells capsazepine carrageenan Catalpa speciosa Celastraceae cell cycle arrest cell proliferation cell signaling cephalotaxine cervical cancer Cheiloclinium cognatum chemotherapeutic adjuvant chemotherapy chiral resolution CIP2A CLE-10 CLEFMA Colocasia esculenta colorectal cancer cells copper Cordyceps sinensis coronarin D CrataBL cryptolepine Cucurbitacin B cytotoxic activity cytotoxicity Dendrobium officinale diallyl disulfide dicentrine DLD-1 cells doxorubicin drug resistance ECD calculation EGFR endoplasmic reticulum stress entrapment efficiency Euphorbia tirucalli FAK/S6K1 flavonoids folk medicine food bioactive FOXO1 fruit Ganoderma tsugae gastric cancer gastric cancer cells gefitinib-resistant NSCLC Gene expression glioblastoma glioblastoma multiforme glioma glucose uptake glycosyltransferase grape leaves human neuroblastoma cells IL-6/JAK2/STAT3 inflammation inflammatory diseases ingenol invasion isochromanes isocryptolepine JNK lactoferrin hydrolysate LC3 lichen Licochalcone A lipogenesis lung adenocarcinoma lysosomal degradation lysosomal membrane permeabilization Magnolia acuminata manganese MAPK MCF-7 cells MDA-MB-231 melanoma melittin mesenchymal stem cells metabolic stability metastasis microenvironment migration mitochondrial membrane potential mitochondrial ROS mitochondrial-dependent pathway molecular mechanism mTOR multiple myeloma n/a naringenin natural compounds natural product alkaloids natural products natural yellow Monascus pigments NCI-60 cancer cell line necrotic neferine neocryptolepine NF-κB no-toxicity Nutraceuticals oncogene osteosarcoma p38 patuletin phenols phloretin phytochemicals PI3K/AKT/mTOR PI3K/Akt/mTOR pathway plant lectin plant-derived foods plantation mode Plenckia populnea porphyran preclinical tests pristimerin pro-apoptotic effects proanthocyanins prostate cancer protease inhibitor protein kinase C protein synthesis inhibition Pulsatilla saponin D quality control quercetagetin quercetin ROS RT-R breast cancer cells Salacia crassifolia Salacia elliptica SB365 seaweed secondary metabolites semi-synthetic derivative SREBP-1 stable nanocapsules stemness potential structure activity relationships structure elucidation tarin Taxus cuspidata temozolomide TNF-α TP traditional preparation transcriptional regulation triterpenoids TRPV1 tumidulin ursolic acid vegetable water-soluble zerumbone Zeylenone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557419703321 |
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Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Characterization of Bioactive Components in Edible Algae
| Characterization of Bioactive Components in Edible Algae |
| Autore | Pereira Leonel |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (226 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
adjuvant
agriculture alginate alkaline phosphatase anticoagulant activity antigen-specific antibody antitumour activity Black Sea bromophenols cancer stem cells carotenoids carrageenan chemical risk chemical sulfation chlorophylls colorectal cancer Cystoseira barbata cytotoxicity diffusion model Ecklonia cava edible seaweed enzymatic extracts EPA feed food FTIR-ATR functional substance HDL-C health health functionality heavy metals adsorption HPLC huBM-MSC isolation keratinocytes LDL-C low molecular weight fucoidan macro algae macroalgae/seaweed marine algae microbial risk minerals mono and polysaccharides Mycoplasma pneumoniae n-3 PUFAs n/a natural resources NK cell NMR nutritional value omics-based technology Osmundea pinnatifida osteoblast particulate matter phlorofucofuroeckol A phlorotannin processed laver product processing technology quantification raw laver reactive oxygen species Sargassum muticum seaweeds TC TC reduction TG Ulva rigida ulvan |
| ISBN | 3-03928-561-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404089303321 |
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Pereira Leonel
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Flavonoids and Their Disease Prevention and Treatment Potential
| Flavonoids and Their Disease Prevention and Treatment Potential |
| Autore | Rupasinghe H.P. Vasantha |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (346 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
A-type proanthocyanidins
Acer okamotoanum afzelin aglycons allodynia amoebiasis analgesia angiogenesis anthocyanin anti-aging activity antiadhesive activity anticancer activity antioxidant activity antiprotozoal agents apigenin apoptosis aspirin bacopaside I bacoside A bacterial sepsis bioguided isolation black rice cyanidin-3-O-glucoside CAM assay cancer cancer chemoprevention cancer prevention cancer stem cells canine cancer cell lines carcinogenesis CD44+/CD24− CDKs cell cycle cell morphology cell proliferation chalcones chronological lifespan citrus citrus flavonoids clinical trials cognition colorectal cancer COVID-19 cranberry CVD cytokines defatted pitaya seed DNA damage dyslipidemia extraction flavan-3-ols flavones flavonoid flavonoid content flavonoids flavonoids and their derivatives foods for health gene and protein regulatory networks glycosides human colon cancer cells hydroxybenzoic acids hyperalgesia hypersensitivity IKKβ, inflammatory cytokines IL-1β IL-6 IL-8 in-vivo angiogenesis infectious diseases inflammation isoquercitrin isorhamnetin lung cancer luteolin macrophages membrane PUFAs profile memory extinction Mexican oregano mice microbiome microglia molecular mechanisms n/a natural products neohesperidin neuroprotection NF-kB NF-κB non-flavonoids obesity passive avoidance test phenolic content phenolic metabolites phytochemicals phytomedicine pro-inflammatory cytokines probiotics quercitrin response surface methodology SAR SARS-COV-2 smart nanoparticles Stat3 synergistic effect tangeretin TNF-α tobacco-specific nitrosamine toll-like receptor 4 UPEC urinary tract infections uropathogenic Escherichia coli UTIs vasorelaxation wood sterols |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557505903321 |
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Rupasinghe H.P. Vasantha
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Hedgehog Signaling in Organogenesis and Tumor Microenvironment
| Hedgehog Signaling in Organogenesis and Tumor Microenvironment |
| Autore | Shimo Tsuyoshi |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (172 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
androgen
animal experiment articular disc basement membrane bone bone disease bone morphogenetic protein cancer stem cells cancer-associated fibroblasts (CAFs) chondrocyte congenital anomalies CRE/LoxP Cyp26 enzymes endochondral ossification epithelial and mesenchymal interaction epithelial-mesenchymal interaction (EMI) external genitalia fracture healing Gli1 growth plate hedgehog hedgehog signaling hedgehog signalling hypospadias Ihh lineage tracing analysis mesenchymal stem cell mouse models n/a oral squamous cell carcinoma (OSCC) osteoarthritis osteoblast penis prostate cancer PTHrP retinoic acid smoothened sonic hedgehog sonic hedgehog (SHH) stem cell stem cell marker synovial joint TMJ tooth development tumor microenvironment (TME) tumor-associated angiogenesis tumor-associated macrophages (TAMs) urethra |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557628803321 |
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Shimo Tsuyoshi
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Immunotherapy, Tumor Microenvironment and Survival Signaling
| Immunotherapy, Tumor Microenvironment and Survival Signaling |
| Autore | Golubovskaya Vita |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (376 p.) |
| Soggetto topico |
Clinical and internal medicine
Medicine and Nursing |
| Soggetto non controllato |
angiogenesis
antigen loss Autophagy BCMA breast cancer cancer cancer immunotherapy cancer metabolism cancer nanomedicine cancer stem cells cancer vaccines CAR macrophage CAR T cell CAR-T CAR-T cells cardiotoxicity CD11 CD18 CD19 CD37 cell therapy cell-cell contact check point inhibitors checkpoint chemotherapy chimeric antigen receptor chimeric antigen receptors clonogenicity colorectal cancer combination therapy crosstalk DCLK1 dendritic cells electroporation hypoxia immune checkpoint inhibitor immune checkpoint inhibitors immune escape immunogenic cell death immunometabolism immunomodulation immunomodulators immunotherapeutic agent immunotherapies immunotherapy lentiviral transduction lentivirus leukemia cells lung metastasis lymphoma lytic peptides macrophages melanoma microenvironment miRNA mitochondria mitochondrial transfer myeloid-derived suppressor cells n/a nanoparticles oncolytic viral therapy pathogenesis pediatric solid tumors personalized medicine programmed cell death 1 ligand 1 programmed cell death protein 1 regulatory T cells resistance risk factors solid tumors targeted therapy targeted treatment triple-negative breast cancer tuft cells tumor tumor antigen tumor antigens tumor immune evasion tumor microenvironment tumor stem cells tumor stroma tunneling nanotubes tyrosine kinase inhibitors β2 integrins |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580205403321 |
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Golubovskaya Vita
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application
| In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application |
| Autore | Baiocchi Marta |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (222 p.) |
| Soggetto topico |
Biology, life sciences
Microbiology (non-medical) Research & information: general |
| Soggetto non controllato |
3D bioprinting
animal models cancer stem cell methods cancer stem cells cancer-on-chip CDX2 chromosomal instability circulating tumor cells clinical translation study clinical trials colon cancer colorectal cancer colorectal carcinoma CRC CTC cluster decitabine DNA damage DNA methylation drug combination drug resistance epithelial mesenchymal transition HIF-1α histological examination hypoxia immunofluorescence analysis immunotherapy in vitro culture machine learning methods mutation analysis organoids patient-derived cancer models patient-derived tumor organoid patient-derived xenograft PDX model precision medicine prognosis radiation response rectal cancer SATB2 ScreenCell® sequential filtration single-cell RNA-sequencing size-based method targeted therapy transcriptional programs tumor cell differentiation tumor heterogeneity tumor metabolism tumor-initiating cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585944103321 |
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Baiocchi Marta
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Natural Products as Anticancer Agents
| Marine Natural Products as Anticancer Agents |
| Autore | Alves Celso |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (150 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
alga
anti-cancer antitumor aplysinopsin analogs apoptosis astaxanthin BH3 mimetics bioactive compounds biscembranoid-type metabolites BT20 cancer stem cells cancer therapy chronic myeloid leukemia colony formation cytotoxicity Ehlich's tumor environment epigenetic signaling epigenome epithelial-mesenchymal transition flaccidoxide-13-acetate gram-scale hepatocellular carcinoma hydroxyphenylacetic acid indole alkaloids inflammation inflammatory factor production invasion LPS-stimulated murine macrophage marine source marine species marine-derived fungus meroterpenoids migration mutp53 n/a nannocystin Nanog natural product Oct4 P. purpurogenum Penicillium chrysogenum polyketide pontin proliferation prostate cancer Sarcophyton digitatum secondary metabolites siRNA STAT3 T47D total synthesis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557595603321 |
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Alves Celso
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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