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Cancer Metabolomics 2018
| Cancer Metabolomics 2018 |
| Autore | Pinto Joana |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (184 p.) |
| Soggetto non controllato |
cell transporters
pharmacodynamics cell growth in vitro study metabolomic signatures endometabolome lung cancer metabolomics chemometric methods bladder cancer mTOR metabolite profiling metabolic pathways hepatocellular carcinoma glutamate senescence MCF7 breath analysis bio actives biomarker gas chromatography–mass spectrometry (GC–MS) GC-MS lung omics nutraceuticals glutaminase metabolism acylcarnitines Erwinaze Kidrolase glutathione targeted metabolomics apoptosis SLC1A5 essential amino acids cancer progression ASCT2 HR MAS alanine analytical platforms volatile organic compound glutaminolysis isotope tracing analysis asparaginase vitamin E breast cancer prognosis early diagnosis tocotrienols NMR prostate cancer in vitro cancer MDA-MB-231 |
| ISBN | 3-03921-346-6 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367563603321 |
Pinto Joana
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cell-Cell and Cell-Matrix Adhesion in Immunobiology and Cancer
| Cell-Cell and Cell-Matrix Adhesion in Immunobiology and Cancer |
| Autore | Murai Toshiyuki |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (138 p.) |
| Soggetto topico |
Medicine
Immunology |
| Soggetto non controllato |
cell adhesion molecule
extracellular matrix immune system cancer progression cytoskeleton cell dynamics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557723603321 |
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Murai Toshiyuki
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Colorectal Cancers: From Present Problems to Future Solutions
| Colorectal Cancers: From Present Problems to Future Solutions |
| Autore | Allgayer Heike |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (238 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
Phage
bacteriophages diet infection colorectal cancer nutrition circulating tumor cells colorectal cancer EPISPOT assay CellSearch® system predictive value chromatin density nanoscale tumour cell heterogeneity microRNAs metastasis super-resolution microscopy early onset cohort epidemiology liquid biopsy biomarker indirect carcinogenesis bovine meat and milk factors (BMMF) chronic zoonosis multiplex tumor immunology immune landscape spontaneous feline intestinal tumors comparative oncology tumor budding CTNNB1 genome-wide methylation array methylation miRNA colon cancer personalized treatment drug combinations Matrix Metalloproteinases (MMPs) polyp TIMPs MMP polymorphisms MMP targeting S100A4 DKK1 Wnt signaling patient survival gender rectal cancer radiochemotherapy radiosensitivity DNA double-strand breaks deposited energy quality of life blood values (molecular) carcinogenesis cancer progression (single) cancer cell heterogeneity models infectious agents (targeted) therapy personalized medicine |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Colorectal Cancers |
| Record Nr. | UNINA-9910585937103321 |
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Allgayer Heike
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
apoptosis
fucoidan hepatocellular carcinoma reactive oxygen species 3-alkylpyridinium polymers nicotine nicotinic acetylcholine receptor non-small cell lung carcinoma melanoma sinulariolide proteomic mitochondria caspase cascade marine fungus sediment anthranilic acid Penicillium paneum cytotoxicity dibromotyrosine mitochondrial dysfunction oxidative stress topoisomerase epigonal organ bonnethead shark Jurkat tumor cell line hippuristanol PEL AP-1 STAT3 Akt colorectal cancer marine mollusc brominated indoles shrimp chemoprevention fatty acids carotenoids cancer nanoparticle osteosarcoma lung metastasis elisidepsin lipid rafts hydroxylated lipids fatty acid 2-hydroxylase cooperative binding membrane permeabilization marine organisms polysaccharides anticancer anticarcinogenic mechanisms of action fumigaclavine C anti-proliferation mitochondrial pathway anti-cancer anti-proliferative carotenoid cell cycle arrest fucoxanthin azoxymethane bioactive natural product isatin in vivo model Marthasterias glacialis L. palmitic acid ER-stress CHOP Antibody Drug Conjugates (ADCs) marine antitumor agents clinical trials approved antitumor agents AD0157 angiogenesis marine drug pyrrolidinedione secondary metabolites cancer preventive chemopreventive trabectedin plitidepsin tumor-associated macrophages tumor microenvironment preclinical anticancer immunity antiangiogenesis fascaplysin cyclin-dependent kinase small cell lung cancer camptothecin poly(ADP-ribose)-polymerase inhibitor breast cancer seaweed therapeutic compounds autophagy marine drugs autophagy inhibitors autophagy inducers macrolide programmed cell death energy stress araguspongine C c-Met HER2 gemcitabine pazopanib phase I safety soft tissue sarcoma pachastrissamine jaspine B carbocyclic analogue sphingosine kinase inhibitor molecular modeling ET-743 DNA minor groove binder soft tissue sarcoma chemotherapy bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) anti-metastatic activity cell adhesion β1-integrin FAK BEL-7402 cell triterpene glycosides sea cucumbers antitumor activities arrest of cell cycle antibacterial marangucyclines deep-sea Streptomyces sp. SCSIO 11594 LS-1 SNU-C5/5-FU TGF-β signaling carcinoembryonic antigen kalkitoxin Moorea producens mitochondria toxin VEGF angiogenesis inhibitor hypoxia-inducible factor-1 HIF-1 Lyngbya majuscula marine metabolites SZ-685C nonfunctioning pituitary adenomas Ecklonia cava phlorotannins dieckol migration sipholenol A ABC transporter multidrug resistance P-gp/ABCB1 BCRP/ABCG2 MRP1/ABCC1 marine natural products glioblastoma xyloketal B proliferation TRPM7 marine compound ribosomal protein genes snoRNA FAU RPS30 SNORA62 evolution Porifera Penicillium brevicompactum Brevianamide Mycochromenic acid derivative antifouling Caribbean sponge plakortide endoperoxide leukemia multi-drug resistant leukemia Sarcophyton ehrenbergi soft coral terpenes cembranoids cytotoxic activity molecular docking uveal melanoma oxidative stress virtual screening Topo I inhibitor low toxic natural product Ulva fasciata selenium-containing polysaccharide-protein complex pseudopterosin NF-κB p65 inflammation cytokine release IL-6 TNFα MCP-1 glucocorticoid receptor paulomycins Micromonospora antitumor Cantabrian Sea-derived actinobacteria puupehenones sponges antiangiogenic antitumoral porifera/sponge cancer genes molecular oncology bromophenol molecular mechanisms cell cycle PI3K/Akt p38/ERK ROS human lung cancer glycosaminoglycans antiproliferative heparan sulphate gliotoxin NSCLC adriamycin resistance Sepia ink polysaccharides antitumour chemosensitization anticoagulation sea anemone drug discovery endothelial cells RGD motif kunitz type inhibitor prostate cancer antioxidant natural marine compounds marine biotechnology microalgae marine sponges Aeroplysinin Isofistularin pheochromocytoma and paraganglioma metastasis cancer progression cell adhesion molecules integrin β1 hypoxia phycocyanin non-small cell lung cancer NF-κB signaling marine-derived drugs bioanalysis chromatography manzamine A epithelial-mesenchymal transition lung cancer circulating tumor cells signal transduction cisplatin Lampetra morii buccal gland cystatin F anti-angiogenesis cystatin superfamily Antimicrobial peptide (AMP) Tilapia piscidin 4 (TP4) non-small cell lung cancer (NSCLC) itampolin A FBDD p38α novel inhibitor tetracenomycin X cyclin D1 proteasomal degradation p38 c-JUN λ-carrageenan heparanase anticoagulant depolymerisation cell migration Aspergillus naphthopyrones endophytic fungus Leathesia nana mangrove-derived actinomycete ansamycins divergolides apoptosis-inducing activity actinomycin EMT invasion low molecular weight fucoidan extract N-Ras neuroblastoma-rat sarcoma Cancer programmed cell death-ligand 1 programmed cell death-ligand 2 human sarcoma cell line (HT1080 cells) human normal diploid fibroblast (TIG-1 cells) chimera chemical conjugation anticancer agent hybridization α9-nicotinic acetylcholine receptors (nAChRs) breast cancer cells αO-conotoxin GeXIVA targeted therapy gorgonian Leptogorgia humulane sesquiterpenoids anticancer activity 12-deacetyl-12-epi-scalaradial HeLa cells Nur77 MAPK/ERK pathway Mycalin A C15 acetogenins synthetic analogues antiproliferative activity A375 and HeLa cell lines polyoxygenated steroids sponge Haliclona gracilis Thalassia testudinum thalassiolin B polyphenols CYP1A1 benzo[a]pyrene JNK1/2 natural products synergism A549 cells cytoskeleton P2X7 receptor pollution anti-angiogenic gene expression HSP90 inhibitor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer
| Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer |
| Autore | Nakayama Naomi |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (258 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
nucleus accumbens-associated protein 1 (NAC1)
BEN (BANP, E5R and NAC1) domain sequence-specific DNA-binding protein solution NMR structure isothermal titration calorimetry (ITC) human cytomegalovirus ovarian cancer cancer progression inflammation immunosuppression endometrial carcinoma immune micro-environment immune checkpoints inhibitors microsatellite instability mismatch repair deficiency platelet-activating factor acetylhydrolase (PAF-AH PLA2G7) BRCA1 mutant ovarian cancer Wnt signaling pGSK3β β-catenin prognosis vulvar melanoma vaginal melanoma targeted therapy gynecological cancer melanoma treatment gene ontology epithelial ovarian cancers borderline ovarian tumors differentially expressed genes aryl hydrocarbon receptor epithelial-mesenchymal transition integrative analysis testin p16 protein cervical cancer cervical neoplasia immunohistochemistry chimeric antigen receptor CD44 adoptive immunotherapy NK cells epithelial ovarian cancer DNA damage response somatic mutation clear cell carcinoma endometrioid endometrial cancer DNA mismatch repair (MMR) MMR deficient (dMMR) long-term survival exosome miRNA biomarkers liquid biopsy interventional radiotherapy vaginal-cuff brachytherapy HDR brachytherapy in vivo dosimetry endometrial cancer biological planning drug repurposing non-coding RNAs nanocarriers anti-angiogenic therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580209103321 |
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Nakayama Naomi
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Paradox Role of Oxidative Stress in Cancer : State of the Art
| Paradox Role of Oxidative Stress in Cancer : State of the Art |
| Autore | Domenicotti Cinzia |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (214 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
sonodynamic therapy
carbon doped titanium dioxide sonosensitizers ultrasound cancer treatment breast cancer treatment radiotherapy hematological malignancies oxidative stress lymphoma leukemia multiple myeloma apoptosis mitochondria ultraviolet-C (UVC) withanolide combined treatment oral cancer DNA damage cancer therapy immune system Hypericum perforatum hyperforin reactive oxygen species pH regulation tumor prevention tumor therapy cancerogenesis inflammatory signaling natural compounds pancreatic cancer antitumor agents coordination polymers bioinorganic chemistry cold atmospheric plasma reactive oxygen and nitrogen species nitrite cancer stem cells chemoresistance glutathione lipid peroxidation ZEB-1 GPX4 ferroptosis HO-1 Nrf2 cancer progression patients therapy prognosis biomarker Eprenetapopt Erastin glutathione (GSH) SLC7A11 iron NRF2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Paradox Role of Oxidative Stress in Cancer |
| Record Nr. | UNINA-9910580205303321 |
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Domenicotti Cinzia
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Developments in Cancer Systems Biology
| Recent Developments in Cancer Systems Biology |
| Autore | Sinha Raghu |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (272 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Sestrin2
lung cancer knockdown cancer progression bioinformatics patient survival lung adenocarcinoma circulating miR-1246 glycosaminoglycan binding prognosis PI3K-Akt signaling pathways TargetScan UBE2C cancer systems biology experimental model systems next-generation sequencing single-cell sequencing patient-derived xenografts patient-derived organoids triple-negative breast cancer personalized medicine computational methods drug repurposing clinical trials cancer stem cells ETS Elk-1 stem cell microarray brain-tumor-initiating cell (BTIC) pancreatic cancer systems biology omics biomarker genomics transcriptomics proteomics metabolomics glycomics metagenomics Ets PEA3 Ets-1 glioma optical genome mapping solid tumors cancer genomics breast ovarian cancer TCGA non-small-cell lung cancer lung adenocarcinoma (LUAD) lung squamous cell carcinoma (LUSC) differential expression SNV CNV risk group signature survival renal cancers protein interactome diagnostic biomarker prognostic biomarker virtual screening docking acute myeloid leukemia Boolean model drug resistance network |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557768503321 |
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Sinha Raghu
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting STAT3 and STAT5 in Cancer
| Targeting STAT3 and STAT5 in Cancer |
| Autore | Moriggl Richard |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (578 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
multiple myeloma
STAT3 S3I-1757 nanoparticle CD38 siRNA/RNAi polyethylenimine PEI lipopolyplex siRNA delivery glioma glioblastoma STAT5 AKT ERK1/2 prolactin androgens prostate cancer knockout escape mechanisms stem/progenitor cells cell hierarchy cancer CD4+ T cells CD8+ T cells myeloid cells immune check point hepatitis C virus (HCV) cirrhosis hepatocellular carcinoma (HCC) endoplasmic reticulum (ER) stress oxidative stress (OS) unfolded protein response (UPR) microRNA-122 (miR-122) nuclear factor erythroid 2-related factor 2 (NRF2) signal transducer and activator of transcription 3 (STAT3) hepatocyte nuclear factor 4 alpha (HNF4A) solid cancers cell cycle apoptosis inflammation mitochondria stemness tumor suppression melanoma autoimmune disease immunotherapy tumor-immune cell interactions breast cancer PD-L1 M2 macrophages NK cells STAT3 inhibitor XIII hedging transaction costs dynamic programming risk management post-decision state variable cancer progression cancer-stem cell cytokine therapy resistance metastasis immunosuppression tumor microenvironment proliferation tyrosine kinase 2 JAK family of protein tyrosine kinases signal transducer and activator of transcription cytokine receptor signaling gain-of-function mutation tumorigenesis ADAM17 interleukin-6 trans-signaling epidermal growth factor receptor (EGF-R) shedding metalloprotease tumor necrosis factor alpha (TNFα) inflammation associated cancer colon cancer lung cancer SH2 domain mutations autosomal-dominant hyper IgE syndrome inflammatory hepatocellular adenomas T-cell large granular lymphocytic leukemia T-cell prolymphocytic leukemia growth hormone insensitivity syndrome nuclear pore complex nuclear transport receptors nucleocytoplasmic shuttling targeting tumor-associated macrophages adoptive T cell therapy immune suppression STAT transcription factors JAK STAT T-PLL T-cell leukemia meta-analysis STAT5B signaling small-molecule inhibitors cancer models companion animals comparative oncology pharmacological inhibitor STAT5 signaling chemotherapy resistance myeloid leukemia heat shock proteins chaperones stabilization targeted therapy ovarian cancer hematopoietic cancers therapeutic targeting pharmacological inhibitors mTOR Bone Marrow Failure Syndromes lymphocytes lymphoma T-cells RHOA NGS MPN JAK2 V617F neoplastic stem cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557623503321 |
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Moriggl Richard
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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