ABC Transporters in Human Diseases |
Autore | Falguières Thomas |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (494 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
ABC transporters
drug action regulatory extension regulatory insertion mechanism of action MRP1 MRP4 breast cancer proliferation migration invasion cAMP ABCG2 ABCB1 blood-brain barrier PET Alzheimer's disease beta-amyloid tariquidar erlotinib ABCG5 ABCG8 ATP-binding cassette transporter cholesterol polar relay sitosterolemia 5' untranslated region cis-acting elements ABCA subfamily bioinformatics ABC transporter therapy response disease-free survival next-generation sequencing competitive allele-specific PCR P-glycoprotein amyloid-beta neuron SK-N-SH gene therapy AAV PFIC BSEP ABCB11 bile salts intrahepatic cholestasis chaperones PFIC2 BRIC ATP-binding cassette transporter A1 (ABCA1) cholesterol homeostasis reverse cholesterol transport HDL-C dyslipidemia type 2 diabetes microparticles ABCG2 genotype clinico-genetic analysis ethnic specificity genetic variations precision medicine rare variant Roma serum uric acid SUA-lowering therapy urate transporter bile secretion ABCB4 ABCC2 ABCG5/G8 molecular partners phytosterol xenosterol atherosclerosis gall stone ABC transporter ABC (ATP-binding cassette) transporters multidrug resistance transport trafficking urate mutations polymorphisms ABCC6 TNAP NT5E Pseudoxanthoma elasticum (PXE) cancer membrane protein functional divergence calcification pseudoxanthoma elasticum generalized arterial calcification of infancy pyrophosphate therapies ABCA7 phagocytosis Aβ peptides yeast multidrug transporter anticancer antifungal resistance mechanism peroxisome adrenoleukodystrophy fatty acids gout early-onset gout hyperuricemia uric acid BCRP single nucleotide polymorphism SNP homology modeling substrate-binding site cellular ATP efflux mutagenesis intracellular traffic MDR3 phosphatidylcholine RAB GTPase taxol drug transport |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910674029103321 |
Falguières Thomas | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Advances in Biological Tissue Biomechanics |
Autore | Lee Chung-Hao |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (242 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
computational fluid dynamics
bileaflet mechanical heart valve adverse hemodynamics transvalvular pressure gradients turbulent shear stresses blood damage platelet activation aortic valve calcification elastin degradation leaflet curvature biomarker early detection porcine brain mechanical behavior hydration effects Split-Hopkinson pressure bar micromechanics finite element analysis collagen crimp elastin microstructures force-controlled mechanical testing the tricuspid valve functional tricuspid regurgitation cardiovascular imaging mechanical characterization in-vitro experiments constitutive modeling geometrical modeling finite element modeling isogeometric analysis (IGA) biaxial mechanical characterization fluid-structure interactions material anisotropy sub-valvular components soft tissue liver high-rate compression polymeric split-Hopkinson pressure bar pentagalloyl glucose aneurysm enzyme biomechanics aorta biaxial mechanical testing cardiac valves osmotic swelling parameter estimation nonlinear preconditioning gradient-based minimization cirrus myocardium stiffness viscoelastic property anisotropy fibrosis the mitral valve collagen fiber architecture glycosaminoglycan uniaxial mechanical testing in-vitro flow loops polarized spatial frequency domain imaging tricuspid regurgitation spatial alignment collagen fiber reorientation in vivo stress/strain quantification constitutive models soft tissues growth and remodeling (G & R) multiscale biomechanics patient-specific modeling |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557104203321 |
Lee Chung-Hao | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Atherosclerosis : Technologies of Personalized Medicine |
Autore | Ragino Yuliya I |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (150 p.) |
Soggetto topico |
Medicine
Cardiovascular medicine |
Soggetto non controllato |
metalloproteinases
calcification atherosclerosis multiplex assay coronary heart disease aspirin resistance non-sensitivity antiplatelet light transmission aggregometry Plateletworks® familial hypercholesterolemia targeted sequencing technologies multiplex ligation-dependent probe amplification LDLR APOB ABCG5 APOC3 LPL SREBF1 rare variants coronary atherosclerosis ischemic heart disease saturated fatty acids monounsaturated fatty acids polyunsaturated fatty acids oxidative stress superoxide dismutase catalase glutathione peroxidase cumulative LDL-C level prognosis DNA methylation epigenetic age myocardial infarction acute coronary syndrome population nested case-control HAPIEE project HAPIEE study atrial fibrillation arterial hypertension obesity diabetes mellitus aging determinants prevalence Russian population cohort Cox regression analysis adiponectin leptin interleukin-6 epicardial adipose tissue perivascular adipose tissue circulating biochemical markers coronary atherosclerosis presence and severity integrated biomarker (i-BIO) validation visual markers lipoprotein(a) immune cells blood count |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Atherosclerosis |
Record Nr. | UNINA-9910566478403321 |
Ragino Yuliya I | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Comorbidities in Chronic Kidney Disease (CKD) |
Autore | Jankowski Joachim |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (184 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
arterial stiffness
carotid–femoral pulse wave velocity hemodialysis p-cresyl sulfate uremic toxins arterial calcification lipid metabolism inflammation coagulation endothelial dysfunction epigenetics chronic kidney disease uremic cardiopathy left ventricular hypertrophy phosphate PTH FGF23 klotho sclerostin chronodisruption chronodisruptor circadian rhythm internal clock uremia uremic cardiomyopathy organ crosstalk cardiorenal syndrome left-ventricular hypertrophy heart failure cardiac fibrosis cardiovascular disease vascular calcification experimental rodent models FGFG23 Klotho Wnt/β-catenin CKD parathyroid hormone secondary hyperparathyroidism uremic toxin ageing end-stage kidney disease premature ageing senescence bone gut cardiovascular CKD–MBD comorbidity fibrosis calcification |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Comorbidities in Chronic Kidney Disease |
Record Nr. | UNINA-9910557705903321 |
Jankowski Joachim | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Coralline Algae: Globally Distributed Ecosystem Engineers |
Autore | Carol Hofmann Laurie |
Pubbl/distr/stampa | Frontiers Media SA, 2020 |
Descrizione fisica | 1 electronic resource (159 p.) |
Soggetto topico |
Science: general issues
Oceanography (seas) |
Soggetto non controllato |
biodiversity
calcification climate change coralline algae genetic and genotypic diversity photosynthesis |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Coralline Algae |
Record Nr. | UNINA-9910557532803321 |
Carol Hofmann Laurie | ||
Frontiers Media SA, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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