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Integrative Multi-Omics in Biomedical Research
| Integrative Multi-Omics in Biomedical Research |
| Autore | Gerner Christopher |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (178 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
target identification
target validation label-free method for drugs anti-angiogenesis mechanism of action receptor tyrosine kinases curcumin natural products lipid lipidomics cardiac metaplasia Barrett's esophagus esophageal adenocarcinoma microbiota DNA sensing IFI16 cGAS innate immunity protein interactions virus-host interactions post-translational modifications mass spectrometry proteomics transcriptomics multi-omics multi-omics analysis study design bioinformatics machine learning analysis flow metabolomics planned myocardial infarction (PMI) myocardial infarction (MI) exercise heart cheminformatics batch variations eicosanoids fetal calf serum peroxisomes host-pathogen interactions secretome macrophages acute myeloid leukemia HL-60 cell line ATRA induced differentiation transcriptome proteome transcription factors key molecules regulatory pathway modelling SRM endometriosis inflammation |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557769003321 |
Gerner Christopher
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Radiation Response Biomarkers for Individualised Cancer Treatments
| Radiation Response Biomarkers for Individualised Cancer Treatments |
| Autore | Badie Christophe |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (231 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
carbon-ion radiotherapy
head-and-neck tumors squamous cell carcinoma radiosensitivity relative biological effectiveness lung cancer radiotherapy radiotherapy monitoring radiation-induced lung injury RILI pneumonitis radiation-induced lung fibrosis RILF circulating biomarkers microRNA micronuclei uterine cervical cancer cGAS STING abscopal effect immunotherapy PBMCS micronucleus assay biological dosimetry human blood genotoxicity tests ionizing radiation biomarkers dicentric assay gamma H2AX foci assay health surveillance analyses clonogenic assays methods plating cancer radiation head and neck cancer exosomes serum metabolomics GC/MS biodosimetry chromosome aberrations normal tissue toxicity predictive tests normal tissue biomarker protein immune infiltrate stroma tumour microenvironment proteomics telomeres chromosomal instability inversions prostate cancer IMRT machine learning individual radiosensitivity late effects personalized medicine liquid biopsy circulating tumour cells extracellular vesicles microRNAs immune system inflammation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557345403321 |
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Badie Christophe
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Spumaretroviruses
| Spumaretroviruses |
| Autore | Khan Arifa |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (352 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
spumavirus
feline illness proviral load neglected virus bovine foamy virus infectious clone particle release cell-free transmission foamy virus spumaretrovirus cross-species virus transmission zoonosis restriction factors immune responses FV vectors virus replication latent infection feline foamy virus epidemiology retrovirus Spumaretrovirus mountain lion Puma concolor ELISA protease reverse transcriptase RNase H reverse transcription antiviral drugs resistance simian foamy virus gibbon lesser apes co-evolution complete viral genome equine foamy virus isolation Japan sero-epidemiology reptile foamy virus endogenous foamy virus endogenous retrovirus ancient retroviruses co-speciation foamy virus-host interactions viral tropism infection kidney cats chronic kidney disease chronic renal disease integrase integration co-infections NHP pathogenesis zoonoses viral prevalence Neotropical primates free-living primates Brazil new world primates simian retrovirus BFV spuma virus model system animal model animal experiment miRNA function gene expression antiviral host restriction gene therapy in-vivo gene therapy hematopoietic stem and progenitor cells foamy virus vector pre-clinical canine model SCID-X1 innate sensing cGAS STING foamy viruses wild ruminants European bison red deer roe deer fallow deer seroreactivity inter-species transmission HSC gene marking FV gene transfer to HSCs gene therapy alternatives serotype high-throughput sequencing replication kinetics cytopathic effect reverse transcriptase activity miRNA expression virus-host-interaction miRNA target gene identification innate immunity ANKRD17 Bif1 (SH3GLB1) replication in vitro |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557409103321 |
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Khan Arifa
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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