ABC Transporters in Human Diseases |
Autore | Falguières Thomas |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (494 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
ABC transporters
drug action regulatory extension regulatory insertion mechanism of action MRP1 MRP4 breast cancer proliferation migration invasion cAMP ABCG2 ABCB1 blood-brain barrier PET Alzheimer's disease beta-amyloid tariquidar erlotinib ABCG5 ABCG8 ATP-binding cassette transporter cholesterol polar relay sitosterolemia 5' untranslated region cis-acting elements ABCA subfamily bioinformatics ABC transporter therapy response disease-free survival next-generation sequencing competitive allele-specific PCR P-glycoprotein amyloid-beta neuron SK-N-SH gene therapy AAV PFIC BSEP ABCB11 bile salts intrahepatic cholestasis chaperones PFIC2 BRIC ATP-binding cassette transporter A1 (ABCA1) cholesterol homeostasis reverse cholesterol transport HDL-C dyslipidemia type 2 diabetes microparticles ABCG2 genotype clinico-genetic analysis ethnic specificity genetic variations precision medicine rare variant Roma serum uric acid SUA-lowering therapy urate transporter bile secretion ABCB4 ABCC2 ABCG5/G8 molecular partners phytosterol xenosterol atherosclerosis gall stone ABC transporter ABC (ATP-binding cassette) transporters multidrug resistance transport trafficking urate mutations polymorphisms ABCC6 TNAP NT5E Pseudoxanthoma elasticum (PXE) cancer membrane protein functional divergence calcification pseudoxanthoma elasticum generalized arterial calcification of infancy pyrophosphate therapies ABCA7 phagocytosis Aβ peptides yeast multidrug transporter anticancer antifungal resistance mechanism peroxisome adrenoleukodystrophy fatty acids gout early-onset gout hyperuricemia uric acid BCRP single nucleotide polymorphism SNP homology modeling substrate-binding site cellular ATP efflux mutagenesis intracellular traffic MDR3 phosphatidylcholine RAB GTPase taxol drug transport |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910674029103321 |
Falguières Thomas | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Advances in the Diagnosis and Treatment of Thyroid Carcinoma |
Autore | Medas Fabio |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (286 p.) |
Soggetto topico |
Medicine
Oncology |
Soggetto non controllato |
thyroid carcinoma
prophylactic central lymph node dissection lymph node metastases RET medullary thyroid carcinoma clinical management variants of uncertain significance differentiated thyroid cancer papillary thyroid cancer minimal extrathyroidal extension radioactive iodine therapy prognosis TNM histology multifocality lymph node metastasis vascular invasion autoimmune thyroid diseases radioiodine refractory Lenvatinib 18F-FDG-PET/CT cost-benefit analysis economics medical thyroid neoplasms radiomics ultrasound magnetic resonance imaging computer tomography prediction classification angiogenic microenvironment prognostic factors antiangiogenic therapy therapeutic target tumor microenvironment tumor behavior proliferation pathways cell cycle control pathways angiogenesis process thyroid cancer Gal-3 expression NIFTP EFVPTC lymphocytic thyroiditis (LT) immunohistochemical (IHC) analysis molecular imaging theranostics companion diagnostics immunoPET anaplastic thyroid cancer poorly thyroid cancer genetic landscape genetically guided therapy fluorodeoxyglucose F18 (18F-FDG) positron emission tomography (PET) magnetic resonance imaging (MRI) recurrence neoplasm metastasis thyroid surgery hypoparathyroidism fluorescence-guided surgery near-infrared autofluorescence PRKAR1A PKA Carney complex cAMP bone metastasis metastasectomy stereotactic radiosurgery ultrasound imaging thyroid nodule fine-needle aspiration papillary thyroid carcinoma lobectomy operative extent CONUT score tyrosine kinase inhibitors |
ISBN | 3-0365-5333-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910619464303321 |
Medas Fabio | ||
MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Cell Signaling in Model Plants |
Autore | Chen Jen-Tsung |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (278 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
salinity
selenium (Se) crops reactive oxygen species (ROS) enzymatic anti-oxidative system drought GA DELLA ABF2 protein-protein interaction Arabidopsis endocytosis microRNAs miPEPs peptides development kinase receptor stress tobacco calcium calcite reactive oxygen species ion channels cellular signalization brassinosteroids receptor-like kinases GSK3-like kinases somatic embryogenesis receptor-like kinases protein phosphatases Malus domestica Rosaceae juvenility FLOWERING LOCUS C flowering Hydrogen sulfide S-sulfhydration plant hormone gasotransmitter disease resistance plant defense herbivore phytohormone plant biotic stress plant signalling Medicago truncatula abiotic stress cAMP cyclic nucleotides-gated channels plant innate immunity Botrytis cinerea tomato iprodione mutant transcriptome analysis metabolism catalytic activity dwarfism gene cloning MNP1 CPS ABA signaling brassinosteroid signaling cascade drought tolerance priming stress adaptation stress memory CRISPR/Cas9 DELLA/TVHYNP Dwarf GA20OX2 GA signaling |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557518203321 |
Chen Jen-Tsung | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Frontiers in the Pharmacological Manipulation of Intracellular cAMP Levels |
Autore | George S. Baillie |
Pubbl/distr/stampa | Frontiers Media SA, 2016 |
Descrizione fisica | 1 electronic resource (191 p.) |
Collana | Frontiers Research Topics |
Soggetto non controllato |
signaling
pharmacological manipulation cyclic adenosine monophosphate Disease Therapeutic applications Homeostasis cAMP Cellular function |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910161647303321 |
George S. Baillie | ||
Frontiers Media SA, 2016 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Mitochondria: From Physiology to Pathology |
Autore | Bruni Francesco |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (196 p.) |
Soggetto topico | Research & information: general |
Soggetto non controllato |
atherosclerosis
carotid intima-media thickness mitochondrial mutations cardiovascular risk factors mitochondria mtDNA cristae mitochondrial fission mitochondrial fusion mitochondrial disease mitochondrial dynamics mitoenergetics mitosteroidogenesis LH cAMP Leydig cell mitochondrial DNA segregation heteroplasmy selective elimination mitophagy mitochondrial engineered nucleases kinases phosphorylation disease PINK1 Parkinson's disease mitochondria homeostasis Cterm MELAS transmitochondrial cybrids aminoacyl-tRNA synthetases LARS2 therapeutic peptides FAD synthase FAD1 mitochondria localization Saccharomyces cerevisiae mRNA mitochondrial localization motif |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Mitochondria |
Record Nr. | UNINA-9910557757603321 |
Bruni Francesco | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Myelin-Mediated Inhibition of Axonal Regeneration: Past, Present, and Future |
Autore | Wilfredo Mellado |
Pubbl/distr/stampa | Frontiers Media SA, 2017 |
Descrizione fisica | 1 electronic resource (116 p.) |
Collana | Frontiers Research Topics |
Soggetto non controllato |
MAG
Omgp axonal regeneration myelin-associated inhibitors CNS regeneration Nogo cAMP |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Myelin-Mediated Inhibition of Axonal Regeneration |
Record Nr. | UNINA-9910227348003321 |
Wilfredo Mellado | ||
Frontiers Media SA, 2017 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The Multi-Dimensional Contributions of Prefrontal Circuits to Emotion Regulation during Adulthood and Critical Stages of Development |
Autore | Roberts Angela |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
Descrizione fisica | 1 electronic resource (188 p.) |
Soggetto non controllato |
norepinephrine
medial prefrontal cortex fear extinction emotion regulation emotion processing connectivity anticipatory arousal Pavlovian triadic neural systems model prelimbic development positive and negative rat Williams Syndrome psychological treatment glia density anxiety fMRI area 25 anhedonia adolescence adolescent autonomic amygdala neuron density neural prefrontal cortex reliability functional magnetic resonance imaging (fMRI) networks cAMP cognitive control extinction infralimbic NMDA reward calcium stress adolescence BDNF machine learning negative affect hierarchical control emotion occasion setting serotonin transporter ventromedial prefrontal cortex psychophysiology depression aging dopamine age |
ISBN | 3-03921-703-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910367741503321 |
Roberts Angela | ||
MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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