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ABC Transporters in Human Diseases
| ABC Transporters in Human Diseases |
| Autore | Falguières Thomas |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (494 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
5' untranslated region
AAV ABC ABC (ATP-binding cassette) transporters ABC transporter ABC transporters ABCA subfamily ABCA7 ABCB1 ABCB11 ABCB4 ABCC2 ABCC6 ABCG2 ABCG2 genotype ABCG5 ABCG5/G8 ABCG8 adrenoleukodystrophy Alzheimer's disease amyloid-beta anticancer antifungal resistance atherosclerosis ATP-binding cassette transporter ATP-binding cassette transporter A1 (ABCA1) Aβ peptides BCRP beta-amyloid bile salts bile secretion bioinformatics blood-brain barrier breast cancer BRIC BSEP calcification cAMP cancer cellular ATP efflux chaperones cholesterol cholesterol homeostasis cis-acting elements clinico-genetic analysis competitive allele-specific PCR disease-free survival drug action drug transport dyslipidemia early-onset gout erlotinib ethnic specificity fatty acids functional divergence gall stone gene therapy generalized arterial calcification of infancy genetic variations gout HDL-C homology modeling hyperuricemia intracellular traffic intrahepatic cholestasis invasion MDR3 mechanism mechanism of action membrane protein microparticles migration molecular partners MRP1 MRP4 multidrug resistance multidrug transporter mutagenesis mutations n/a neuron next-generation sequencing NT5E P-glycoprotein peroxisome PET PFIC PFIC2 phagocytosis phosphatidylcholine phytosterol polar relay polymorphisms precision medicine proliferation pseudoxanthoma elasticum Pseudoxanthoma elasticum (PXE) pyrophosphate RAB GTPase rare variant regulatory extension regulatory insertion reverse cholesterol transport Roma serum uric acid single nucleotide polymorphism sitosterolemia SK-N-SH SNP SUA-lowering therapy substrate-binding site tariquidar taxol therapies therapy response TNAP trafficking transport transporter type 2 diabetes urate urate transporter uric acid xenosterol yeast |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674029103321 |
Falguières Thomas
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Autism Research
| Advances in Autism Research |
| Autore | Narzisi Antonio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (400 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
2019-nCoV
ABA accuracy action observation action prediction adolescence adulthood adults adults and adolescents affiliative behavior alexithymia amygdala antibodies anxiety AQ art ASD Asperger syndrome assessment attention deficit and hyperactivity disorder attention to detail autism autism in adulthood autism spectrum disorder autism spectrum disorder (ASD) Autism Spectrum Disorder (ASD) autism spectrum disorders autistic traits autistic-like features autonomic nervous system Bayesian false-discovery probability (BFDP) behavioral intervention belief biomarker biomarker discovery bipolar disorder blood-brain barrier BOT-2 broader autism phenotype cannabidiol cannabidivarin cannabinoids central coherence cerebrospinal fluid challenging behavior challenging behaviors child and adolescent psychiatry cognition communication comorbidity compulsion context coronavirus cortisol COSMIN COVID-19 cross-cultural generalisability cytokines dental care depression developmental language disorder developmental trajectories diagnosis disruptive behavior disorders dopamine Draw-a-Man drawings maturity early detection early intensive behavioral intervention early intensive intervention early intervention early screening Early Start Denver Model EEG empathy employment epilepsy ERP Europe executive functions experience eye tracking false positive report probability (FPRP) feeding problems First Year Inventory frontal EEG alpha asymmetry GAD65 gastrointestinal Genome-Wide Association Studies (GWAS) Gilles de la Tourette grammatical comprehension group activity Gulf health system high-functioning autism high-risk infants HMD human figure drawings hyperactivity hypothalamus ICT identify imitation immersive virtual reality infant screening infants infection insight intellectual disability intervention IVR joint attention knowledge language language acquisition language profiles level 1 and level 2 screening tools literature review longitudinal machine learning medical procedures mental health prevention meta-analysis metabolomics microbiome migration moderators and mediators of intervention motion analysis motor development motor performance skills mouse social behavior n/a neurodevelopment neurodevelopmental disorders neuroimaging neuroinflammation obsession oral health oxytocin p-cresol PAI-1 parents PEERS® perspective-taking persuasive text writing postural balance precise medicine preconception risk factor predictors preschool teachers prevalence estimate prion priors PRISMA problem behaviors proprioception psychopathology psychosis RCT regression regressive autism reward response RewP risk schizophrenia screening self-awareness self-efficacy self-motion semantic features sensitization sensorimotor integration sensory experience questionnaire (SEQ) sensory profile sensory responsiveness short sensory profile (SSP) side effects sign language skills sleep social behavior social cognition social impairment social interaction social perception social skills intervention social-cognitive development stereotypical behaviors stress study design suicidal attempts suicidal ideation surveillance review systematic review TAS-20 technology telehealth THC theory of mind toddlers TSIA validity video signal processing vision visual impairment wearable sensors wearable technologies word learning |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557596603321 |
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Narzisi Antonio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Autism Research
| Advances in Autism Research |
| Autore | Narzisi Antonio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (434 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
2019-nCoV
ABA accuracy action observation action prediction adolescence adulthood adults adults and adolescents affiliative behavior alexithymia amygdala antibodies anxiety AQ art ASD Asperger syndrome assessment attention deficit and hyperactivity disorder attention to detail autism autism in adulthood autism spectrum disorder autism spectrum disorder (ASD) Autism Spectrum Disorder (ASD) autism spectrum disorders autistic traits autistic-like features autonomic nervous system Bayesian false-discovery probability (BFDP) behavioral intervention belief biomarker biomarker discovery bipolar disorder blood-brain barrier BOT-2 broader autism phenotype cannabidiol cannabidivarin cannabinoids central coherence cerebrospinal fluid challenging behavior challenging behaviors child and adolescent psychiatry cognition communication comorbidity compulsion context coronavirus cortisol COSMIN COVID-19 cross-cultural generalisability cytokines dental care depression developmental language disorder developmental trajectories diagnosis disruptive behavior disorders dopamine Draw-a-Man drawings maturity early detection early intensive behavioral intervention early intensive intervention early intervention early screening Early Start Denver Model EEG empathy employment epilepsy ERP Europe executive functions experience eye tracking false positive report probability (FPRP) feeding problems First Year Inventory frontal EEG alpha asymmetry GAD65 gastrointestinal Genome-Wide Association Studies (GWAS) Gilles de la Tourette grammatical comprehension group activity Gulf health system high-functioning autism high-risk infants HMD human figure drawings hyperactivity hypothalamus ICT identify imitation immersive virtual reality infant screening infants infection insight intellectual disability intervention IVR joint attention knowledge language language acquisition language profiles level 1 and level 2 screening tools literature review longitudinal machine learning medical procedures mental health prevention meta-analysis metabolomics microbiome migration moderators and mediators of intervention motion analysis motor development motor performance skills mouse social behavior n/a neurodevelopment neurodevelopmental disorders neuroimaging neuroinflammation obsession oral health oxytocin p-cresol PAI-1 parents PEERS® perspective-taking persuasive text writing postural balance precise medicine preconception risk factor predictors preschool teachers prevalence estimate prion priors PRISMA problem behaviors proprioception psychopathology psychosis RCT regression regressive autism reward response RewP risk schizophrenia screening self-awareness self-efficacy self-motion semantic features sensitization sensorimotor integration sensory experience questionnaire (SEQ) sensory profile sensory responsiveness short sensory profile (SSP) side effects sign language skills sleep social behavior social cognition social impairment social interaction social perception social skills intervention social-cognitive development stereotypical behaviors stress study design suicidal attempts suicidal ideation surveillance review systematic review TAS-20 technology telehealth THC theory of mind toddlers TSIA validity video signal processing vision visual impairment wearable sensors wearable technologies word learning |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557449103321 |
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Narzisi Antonio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Aging and Age-Related Disorders : : From Molecular Mechanisms To Therapies / / Vladimir Titorenko
| Aging and Age-Related Disorders : : From Molecular Mechanisms To Therapies / / Vladimir Titorenko |
| Autore | Titorenko Vladimir |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (322 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
advanced glycated end products
microRNAs differentiation transcription skin absorption cellular quiescence lifespan longevity genes protein kinases self-renewal circadian blood-brain barrier aging-related disorders sirtuin-1 inflammation arterial aging reactive oxygen species electron microscopy reconstructed human skin rejuvenation low-dose fluvastatin and valsartan combination inflammaging hematopoietic stem cell aging cell cycle mitochondria ribose the nervous system nanomedicine proteostasis adult stem cells immunosenescence cell signaling mechanisms of quiescence maintenance metabolism aging melatonin diabetes mechanisms of quiescence entry and exit Drosophila melanogaster GSK3 (glycogen synthase kinase 3) |
| ISBN |
9783039213566
3039213563 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367567903321 |
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Titorenko Vladimir
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Brain-Targeted Drug Delivery
| Brain-Targeted Drug Delivery |
| Autore | Sousa Flávia |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (260 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
3D cell culture systems
acetaminophen Alzheimer's disease Alzheimer's disease-relevant tau species anti-tau and anti-receptor bispecific monoclonal antibodies blood-brain barrier brain biodistribution brain cancer brain targeted therapy central composite rotatable design cerebral open flow microperfusion cerebrospinal fluid microcirculation chemoattractant claudin-5 CNS drug delivery convection-enhanced delivery CXCL CXCR delivery to brain depression diffuse midline glioma drug delivery drug delivery into the brain electrochemical biosensors GB-13 gene therapy glioblastoma glioblastoma multiforme glycol chitosan high-grade glioma hyaluronidase IL-13 IL-13Rα2 IL13.E13K-PE4E immunotherapy immunotoxin improved memory interactions between Aβ and tau intranasal delivery laser liposome macromolecules memory impairment microdialysis microparticles movement impairment n/a nanoparticle nanoparticles nanostructured lipid carrier naringenin nasal delivery system neurosurgery non-human primate nose to brain delivery opioids optogenetics Parkinson's disease phospholipid oily gel PLGA polyplexes pomegranate seed oil receptor expression seizure targeted therapy tau clearance in microglia tau clearance in neurons temporal-spatial pathological Aβ and tau distribution tight junction tolcapone transendothelium based on receptor-mediated transcytosis ultrasound |
| ISBN | 3-0365-5281-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619467203321 |
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Sousa Flávia
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Delivery Technology Development in Canada
| Drug Delivery Technology Development in Canada |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (352 p.) |
| Disciplina | 615.1/900971 |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
3D spheroid
adenanthin amphotericin B antibodies bacteriophage bioaccessibility biodistribution biological barriers biologicals blood-brain barrier blood-brain barrier (BBB) Canada cancer canola oil deodorizer distillate cationic gemini surfactant child friendly formulation chronotherapy circadian clock cisplatin clinical trials co-delivery combination therapy controlled drug delivery developing world dissolution DOX-Vit D doxorubicin drug delivery drug delivery systems drug development drug discovery drug-resistant melanoma EGFR-targeted therapy emulsion encapsulation flavonoids formulation and dosage form development fungal infections gambogic acid gastrointestinal simulator GE11 peptide HAV6 cadherin peptide head and neck squamous cell carcinoma HIF-1 hypoxia-induced chemoresistance inclusion complex innovation intra-arterial chemotherapy lipid nanoparticles liposome liposomes loading gradients magnetic fields magnetic resonance imaging (MRI) malignant gliomas medical devices medulloblastoma mefloquine melphalan Metaplex MG63 model orange juice mouse models nanoparticles nifedipine oral oral delivery oral formulation parasitic infections permeation enhancers phage display pharmaceutics pharmacokinetics pharmacological Inhibitors of HIF-1 and STAT3 phospholipid complex photostabilizers phytosterols plant polymeric micelle precision medicine primary central nervous system lymphomas quercetin radiation radiolabeling remote loading ROESY NMR spectroscopy rosmarinic acid route of administration skin small molecules STAT3 staurosporine sustained delivery targeted therapies throughput TNO gastrointestinal model tocopherols topical formulation transdermal drug delivery transient modulation translational research triggered drug release ultrasound virus Vitamin D water miscible solvents |
| ISBN | 3-03928-005-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367736503321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Human African Trypanosomiasis (Sleeping Sickness) : The Road to Elimination Revisited-Achievements and Remaining Challenges
| Human African Trypanosomiasis (Sleeping Sickness) : The Road to Elimination Revisited-Achievements and Remaining Challenges |
| Autore | Burri Christian |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (280 p.) |
| Soggetto topico |
Epidemiology and Medical statistics
Medicine and Nursing |
| Soggetto non controllato |
(+)-spectaline
acoziborole active follow-up strategy adverse event African sleeping sickness African trypanosomiasis animal reservoirs apoptosis association study autophagy blood-brain barrier brain permeability case detection CATT positive serological suspects chemotherapy clinical research cross-talk development of treatment diagnosis disease elimination disease eradication donor policy DR Congo drug discovery drug resistance drugs elimination embodiment encephalopathy eradication expertise fexinidazole flagellar pocket frontline workers g-HAT Haemoparasites health system strengthening high-throughput screening history home-based treatment human Africa trypanosomiasis human African trypanosomiasis Human African Trypanosomiasis (HAT) human leukocyte antigen iron iso-6-spectaline medical history medical innovation melarsoprol mobile screening mydriasis n/a neglected tropical diseases neurological signs nutritional immunity oligosymptomatic HAT pafuramidine patient-centred care pharmacology phenotypic drug screening political history product development partnerships qualitative methods r-HAT re-emergence research and development sequelae serendipity serology sleeping sickness South Sudan suramin symptoms T. b. gambiense T. b. rhodesiense transferrin transferrin receptor treatment treatment-seeking trypanosoma brucei Trypanosoma brucei Trypanosoma brucei rhodesiense Trypanosoma growth inhibitors trypanosomosis Uganda |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Human African Trypanosomiasis |
| Record Nr. | UNINA-9910557288503321 |
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Burri Christian
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Microbial Virulence Factors
| Microbial Virulence Factors |
| Autore | Leitão Jorge H |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (400 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
5637 bladder cells
actin actin proteolysis Actinomycetales Aeromonas hydrophila anti-virulence antibiotic resistance antimicrobial peptide antimicrobial peptides apple apple proliferation autotransporter bacteria bacterial invasion bacterial pathogens bacterial surface protein biofilm biofilm formation blood-brain barrier blood-cerebrospinal fluid barrier Bordetella pertussis Burkholderia cepacia complex Candida Candida albicans chronic infection Citrobacter coagulase-negative staphylococci complement compound appressorium covalent labeling cystic fibrosis cytotoxicity Dickeya solani differential expression proteins EDTA effector protein Enterobacter Enterobacterales fluconazole fungal pathogens fungicidal activity gelatin gene expression global regulator grimelysin Hfq host-pathogen interaction hyphae immune evasion immune response infection inflammation inter-kingdom protection interspecies interactions intracellular survival Klebsiella lon expression LysR-family manipulation meningitis metalloproteinases microbial virulence factors morphology motility mucin omics analysis outer membrane vesicles (OMVs) oxidative stress pathogenicity pathogenomics pectinolytic enzymes persistence phytoplasma plant pathogen primary ciliary dyskinesia protealysin protease ECP 32 protease Lon proteomics analysis Pseudomonas aeruginosa pyolysin replicative niche resistance to stress Salmonella enterica serovar Typhimurium Sclerotinia sclerotiorum serine proteases serum resistance small noncoding regulatory RNAs solute-binding proteins SPATEs sputum SpyCatcher SsNsd1 T3SS topology mapping truA Trueperella pyogenes two-dimensional electrophoresis type III secretion system usg UTIs virulence virulence factor virulence factors whole genome sequencing ΔlahS |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557746603321 |
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Leitão Jorge H
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondria-targeted drug delivery
| Mitochondria-targeted drug delivery |
| Autore | Kopecka Joanna |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (290 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
alkylphospholipid analog
anticancer peptide (ACP) anticancer peptides antimicrobial peptide (AMP) antimicrobial peptides antitumor agents ATP production blood-brain barrier cancer drug resistance cancer metabolism cardiovascular disease central nervous system cholesterol cytotoxic effect differentiation diphenyleneiodonium drug delivery edelfosine endothelial fluorescence lifetime imaging gene therapy heteroplasmy host defense peptides hypoxia inflammation lipid raft LPS malate-aspartate shuttle medicinal chemistry melanoma metabolic drug metabolism mitochondria mitochondria dysfunctions mitochondria-targeted antioxidants mitochondrial carrier mitochondrial disease mitochondrial disorders mitochondrial DNA mitochondrial gene delivery mitochondrial oncometabolites mitochondrial permeability transition pore mitochondrial ROS n/a NADPH-oxidase nanocarriers neuron oxidative stress oxoglutarate carrier pharmacological therapy plumbagin precision medicine prediction proliferation random forest reactive oxygen species retinal ischemia tunneling nanotubules |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576881503321 |
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Kopecka Joanna
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy
| Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy |
| Autore | Ruvo Menotti |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (278 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
adoptive immunotherapy
affibody molecules affinity aggregation AL amyloidosis amyloid anti-CD38 MoAb antibody antibody fragment antibody fragments Antibody-Drug Conjugate antibody-drug conjugates BCMA belantamab mafodotin bispecific bispecific T-cell engager blood-brain barrier cancer therapy CAR adaptor CD38 cDNA CHI3L1 chimeric antigen receptor (CAR T) chimeric antigen receptor T-cells cross-linking Daratumumab developability drug targeting E. coli Fab glutamate carboxypeptidase II guinea pig idecabtagene vicleucel immunization immunogenicity in vivo imaging Isatuximab JNJ-68284528 lung metastasis Mabs modular CAR T monoclonal antibodies monoclonal antibody myeloma NAALADase neurodegenerative disorders neurotoxicity non-specific binding nucleocapsid NUsc1 oligomer payload phage display pharmacokinetics polyspecificity porcine deltacoronavirus prostate cancer prostate-specific membrane antigen protein engineering protocol receptor-mediated transcytosis scFv self-association single chain solubility specificity split CAR stability transferrin receptor universal CAR T universal immune receptor viscosity YKL-40 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557613003321 |
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Ruvo Menotti
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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