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ABC Transporters in Human Diseases
| ABC Transporters in Human Diseases |
| Autore | Falguières Thomas |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (494 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
ABC transporters
drug action regulatory extension regulatory insertion mechanism of action MRP1 MRP4 breast cancer proliferation migration invasion cAMP ABCG2 ABCB1 blood-brain barrier PET Alzheimer's disease beta-amyloid tariquidar erlotinib ABCG5 ABCG8 ATP-binding cassette transporter cholesterol polar relay sitosterolemia 5' untranslated region cis-acting elements ABCA subfamily bioinformatics ABC transporter therapy response disease-free survival next-generation sequencing competitive allele-specific PCR P-glycoprotein amyloid-beta neuron SK-N-SH gene therapy AAV PFIC BSEP ABCB11 bile salts intrahepatic cholestasis chaperones PFIC2 BRIC ATP-binding cassette transporter A1 (ABCA1) cholesterol homeostasis reverse cholesterol transport HDL-C dyslipidemia type 2 diabetes microparticles ABCG2 genotype clinico-genetic analysis ethnic specificity genetic variations precision medicine rare variant Roma serum uric acid SUA-lowering therapy urate transporter bile secretion ABCB4 ABCC2 ABCG5/G8 molecular partners phytosterol xenosterol atherosclerosis gall stone ABC transporter ABC (ATP-binding cassette) transporters multidrug resistance transport trafficking urate mutations polymorphisms ABCC6 TNAP NT5E Pseudoxanthoma elasticum (PXE) cancer membrane protein functional divergence calcification pseudoxanthoma elasticum generalized arterial calcification of infancy pyrophosphate therapies ABCA7 phagocytosis Aβ peptides yeast multidrug transporter anticancer antifungal resistance mechanism peroxisome adrenoleukodystrophy fatty acids gout early-onset gout hyperuricemia uric acid BCRP single nucleotide polymorphism SNP homology modeling substrate-binding site cellular ATP efflux mutagenesis intracellular traffic MDR3 phosphatidylcholine RAB GTPase taxol drug transport |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674029103321 |
Falguières Thomas
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Autism Research . Volume 1
| Advances in Autism Research . Volume 1 |
| Autore | Narzisi Antonio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (400 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
autism spectrum disorder
infants frontal EEG alpha asymmetry early detection autism spectrum disorders toddlers eye tracking joint attention longitudinal regression cytokines PAI-1 neuroinflammation gastrointestinal autism literature review comorbidity early intervention early intensive behavioral intervention behavioral intervention First Year Inventory early screening risk cross-cultural generalisability validity preschool teachers self-efficacy knowledge belief skills identify autism spectrum disorder (ASD) level 1 and level 2 screening tools systematic review COSMIN PRISMA screening infection prion meta-analysis motion analysis video signal processing neurodevelopmental disorders infant screening developmental language disorder semantic features word learning central coherence biomarker p-cresol mouse social behavior dopamine ASD vision proprioception self-motion immersive virtual reality IVR HMD technology persuasive text writing perspective-taking adolescence intervention sign language imitation cognition language acquisition prevalence estimate predictors surveillance review Autism Spectrum Disorder (ASD) early intensive intervention developmental trajectories moderators and mediators of intervention psychosis schizophrenia psychopathology AQ accuracy attention to detail self-awareness insight preconception risk factor Gilles de la Tourette obsession compulsion social behavior social impairment sensory profile sensory responsiveness feeding problems short sensory profile (SSP) sensory experience questionnaire (SEQ) coronavirus 2019-nCoV neurodevelopment child and adolescent psychiatry mental health prevention Asperger syndrome adults cerebrospinal fluid antibodies blood-brain barrier GAD65 Early Start Denver Model high-risk infants motor development high-functioning autism language experience communication autonomic nervous system wearable technologies EEG theory of mind adults and adolescents human figure drawings Draw-a-Man drawings maturity social perception ERP reward response RewP sensitization social skills intervention PEERS® adulthood diagnosis autistic traits action observation action prediction context priors hypothalamus amygdala oxytocin social cognition social interaction affiliative behavior neuroimaging COVID-19 challenging behavior dental care oral health medical procedures ICT wearable sensors migration Europe health system autism in adulthood intellectual disability regressive autism epilepsy challenging behaviors empathy executive functions attention deficit and hyperactivity disorder disruptive behavior disorders alexithymia anxiety depression TAS-20 TSIA parents broader autism phenotype autistic-like features social-cognitive development stereotypical behaviors visual impairment language profiles grammatical comprehension cannabinoids cannabidiol cannabidivarin THC problem behaviors sleep hyperactivity side effects motor performance skills Gulf BOT-2 machine learning employment telehealth ABA RCT cortisol group activity stress art assessment sensorimotor integration postural balance false positive report probability (FPRP) Bayesian false-discovery probability (BFDP) Genome-Wide Association Studies (GWAS) microbiome metabolomics study design biomarker discovery precise medicine bipolar disorder suicidal ideation suicidal attempts |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557596603321 |
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Narzisi Antonio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Autism Research . Volume 2
| Advances in Autism Research . Volume 2 |
| Autore | Narzisi Antonio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (434 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
autism spectrum disorder
infants frontal EEG alpha asymmetry early detection autism spectrum disorders toddlers eye tracking joint attention longitudinal regression cytokines PAI-1 neuroinflammation gastrointestinal autism literature review comorbidity early intervention early intensive behavioral intervention behavioral intervention First Year Inventory early screening risk cross-cultural generalisability validity preschool teachers self-efficacy knowledge belief skills identify autism spectrum disorder (ASD) level 1 and level 2 screening tools systematic review COSMIN PRISMA screening infection prion meta-analysis motion analysis video signal processing neurodevelopmental disorders infant screening developmental language disorder semantic features word learning central coherence biomarker p-cresol mouse social behavior dopamine ASD vision proprioception self-motion immersive virtual reality IVR HMD technology persuasive text writing perspective-taking adolescence intervention sign language imitation cognition language acquisition prevalence estimate predictors surveillance review Autism Spectrum Disorder (ASD) early intensive intervention developmental trajectories moderators and mediators of intervention psychosis schizophrenia psychopathology AQ accuracy attention to detail self-awareness insight preconception risk factor Gilles de la Tourette obsession compulsion social behavior social impairment sensory profile sensory responsiveness feeding problems short sensory profile (SSP) sensory experience questionnaire (SEQ) coronavirus 2019-nCoV neurodevelopment child and adolescent psychiatry mental health prevention Asperger syndrome adults cerebrospinal fluid antibodies blood-brain barrier GAD65 Early Start Denver Model high-risk infants motor development high-functioning autism language experience communication autonomic nervous system wearable technologies EEG theory of mind adults and adolescents human figure drawings Draw-a-Man drawings maturity social perception ERP reward response RewP sensitization social skills intervention PEERS® adulthood diagnosis autistic traits action observation action prediction context priors hypothalamus amygdala oxytocin social cognition social interaction affiliative behavior neuroimaging COVID-19 challenging behavior dental care oral health medical procedures ICT wearable sensors migration Europe health system autism in adulthood intellectual disability regressive autism epilepsy challenging behaviors empathy executive functions attention deficit and hyperactivity disorder disruptive behavior disorders alexithymia anxiety depression TAS-20 TSIA parents broader autism phenotype autistic-like features social-cognitive development stereotypical behaviors visual impairment language profiles grammatical comprehension cannabinoids cannabidiol cannabidivarin THC problem behaviors sleep hyperactivity side effects motor performance skills Gulf BOT-2 machine learning employment telehealth ABA RCT cortisol group activity stress art assessment sensorimotor integration postural balance false positive report probability (FPRP) Bayesian false-discovery probability (BFDP) Genome-Wide Association Studies (GWAS) microbiome metabolomics study design biomarker discovery precise medicine bipolar disorder suicidal ideation suicidal attempts |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557449103321 |
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Narzisi Antonio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Aging and Age-related Disorders: From Molecular Mechanisms to Therapies
| Aging and Age-related Disorders: From Molecular Mechanisms to Therapies |
| Autore | Titorenko Vladimir |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (322 p.) |
| Soggetto non controllato |
advanced glycated end products
microRNAs differentiation transcription skin absorption cellular quiescence lifespan longevity genes protein kinases self-renewal circadian blood-brain barrier aging-related disorders sirtuin-1 inflammation arterial aging reactive oxygen species electron microscopy reconstructed human skin rejuvenation low-dose fluvastatin and valsartan combination inflammaging hematopoietic stem cell aging cell cycle mitochondria ribose the nervous system nanomedicine proteostasis adult stem cells immunosenescence cell signaling mechanisms of quiescence maintenance metabolism aging melatonin diabetes mechanisms of quiescence entry and exit Drosophila melanogaster GSK3 (glycogen synthase kinase 3) |
| ISBN | 3-03921-356-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Aging and Age-related Disorders |
| Record Nr. | UNINA-9910367567903321 |
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Titorenko Vladimir
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Brain-Targeted Drug Delivery
| Brain-Targeted Drug Delivery |
| Autore | Sousa Flávia |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
drug delivery into the brain
transendothelium based on receptor-mediated transcytosis immunotherapy Alzheimer's disease anti-tau and anti-receptor bispecific monoclonal antibodies Alzheimer's disease-relevant tau species temporal-spatial pathological Aβ and tau distribution interactions between Aβ and tau tau clearance in microglia tau clearance in neurons liposome nanoparticle seizure laser ultrasound naringenin nanostructured lipid carrier intranasal delivery central composite rotatable design depression pomegranate seed oil nasal delivery system memory impairment movement impairment delivery to brain improved memory phospholipid oily gel high-grade glioma diffuse midline glioma glioblastoma IL-13Rα2 IL-13 immunotoxin targeted therapy GB-13 IL13.E13K-PE4E receptor expression acetaminophen blood-brain barrier claudin-5 CNS drug delivery opioids tight junction microdialysis cerebral open flow microperfusion electrochemical biosensors macromolecules tolcapone microparticles nanoparticles PLGA Parkinson's disease nose to brain delivery gene therapy polyplexes hyaluronidase glycol chitosan brain cancer chemoattractant CXCL CXCR glioblastoma multiforme 3D cell culture systems non-human primate convection-enhanced delivery neurosurgery optogenetics brain targeted therapy drug delivery cerebrospinal fluid microcirculation brain biodistribution |
| ISBN | 3-0365-5281-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619467203321 |
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Sousa Flávia
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug delivery technology development in Canada / / special issue editors, Kishor M. Wasan, Ildiko Badea
| Drug delivery technology development in Canada / / special issue editors, Kishor M. Wasan, Ildiko Badea |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (352 p.) |
| Disciplina | 615.1/900971 |
| Soggetto topico | Drug Delivery Systems - Canada |
| Soggetto non controllato |
encapsulation
biodistribution pharmaceutics targeted therapies gambogic acid GE11 peptide formulation and dosage form development transient modulation ROESY NMR spectroscopy bioaccessibility polymeric micelle pharmacological Inhibitors of HIF-1 and STAT3 nanoparticles Vitamin D drug discovery EGFR-targeted therapy translational research clinical trials doxorubicin dissolution drug development permeation enhancers Canada plant primary central nervous system lymphomas photostabilizers head and neck squamous cell carcinoma mouse models drug delivery systems melphalan hypoxia-induced chemoresistance skin virus circadian clock child friendly formulation adenanthin co-delivery canola oil deodorizer distillate Metaplex innovation controlled drug delivery nifedipine radiolabeling amphotericin B biological barriers blood-brain barrier (BBB) biologicals lipid nanoparticles oral formulation phytosterols medical devices chronotherapy oral cationic gemini surfactant route of administration drug delivery intra-arterial chemotherapy developing world sustained delivery water miscible solvents combination therapy antibodies throughput magnetic fields liposomes medulloblastoma drug-resistant melanoma rosmarinic acid topical formulation TNO gastrointestinal model gastrointestinal simulator malignant gliomas transdermal drug delivery oral delivery precision medicine 3D spheroid flavonoids staurosporine DOX-Vit D loading gradients bacteriophage phospholipid complex triggered drug release HIF-1 phage display pharmacokinetics emulsion quercetin cisplatin parasitic infections remote loading HAV6 cadherin peptide blood-brain barrier inclusion complex tocopherols STAT3 ultrasound liposome fungal infections magnetic resonance imaging (MRI) MG63 model orange juice radiation cancer mefloquine small molecules |
| ISBN | 3-03928-005-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367736503321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Human African Trypanosomiasis (Sleeping Sickness) : The Road to Elimination Revisited-Achievements and Remaining Challenges
| Human African Trypanosomiasis (Sleeping Sickness) : The Road to Elimination Revisited-Achievements and Remaining Challenges |
| Autore | Burri Christian |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (280 p.) |
| Soggetto topico |
Medicine
Epidemiology & medical statistics |
| Soggetto non controllato |
(+)-spectaline
iso-6-spectaline Trypanosoma brucei rhodesiense autophagy apoptosis cross-talk trypanosomosis iron transferrin transferrin receptor nutritional immunity flagellar pocket Human African Trypanosomiasis (HAT) mydriasis neurological signs eradication re-emergence human African trypanosomiasis treatment melarsoprol adverse event encephalopathy human leukocyte antigen association study disease elimination disease eradication frontline workers DR Congo mobile screening qualitative methods sequelae serology oligosymptomatic HAT product development partnerships research and development medical innovation donor policy African trypanosomiasis sleeping sickness trypanosoma brucei drugs drug resistance history human Africa trypanosomiasis fexinidazole home-based treatment patient-centred care Uganda elimination T. b. gambiense g-HAT T. b. rhodesiense r-HAT neglected tropical diseases Trypanosoma brucei drug discovery high-throughput screening blood-brain barrier brain permeability pharmacology phenotypic drug screening Haemoparasites animal reservoirs Trypanosoma growth inhibitors chemotherapy pafuramidine acoziborole African sleeping sickness development of treatment suramin medical history political history clinical research health system strengthening South Sudan diagnosis symptoms treatment-seeking case detection embodiment expertise serendipity CATT positive serological suspects active follow-up strategy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Human African Trypanosomiasis |
| Record Nr. | UNINA-9910557288503321 |
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Burri Christian
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondria-targeted drug delivery
| Mitochondria-targeted drug delivery |
| Autore | Kopecka Joanna |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (290 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
retinal ischemia
blood-brain barrier endothelial reactive oxygen species oxidative stress tunneling nanotubules neuron central nervous system inflammation hypoxia anticancer peptide (ACP) antimicrobial peptide (AMP) anticancer peptides antimicrobial peptides host defense peptides prediction random forest mitochondria mitochondrial DNA mitochondrial disorders pharmacological therapy gene therapy precision medicine cardiovascular disease drug delivery mitochondria dysfunctions nanocarriers oxoglutarate carrier malate-aspartate shuttle cancer metabolism ATP production diphenyleneiodonium NADPH-oxidase differentiation proliferation mitochondria-targeted antioxidants LPS mitochondrial ROS antitumor agents fluorescence lifetime imaging medicinal chemistry metabolic drug mitochondrial carrier melanoma plumbagin cytotoxic effect metabolism cholesterol lipid raft mitochondrial permeability transition pore alkylphospholipid analog edelfosine mitochondrial oncometabolites cancer drug resistance mitochondrial disease heteroplasmy mitochondrial gene delivery |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576881503321 |
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Kopecka Joanna
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nanobody
| Nanobody |
| Autore | Rothbauer Ulrich |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Bacillus anthracis
immunoassay single-domain antibody genetic fusion Beta galactosidase P-type ATPase nanobody llama Zinc-transport Zinc-transporting P-ATPase ZntA TNF fluorescent nanobodies sensor anti-cytokine therapy autoimmune disease Western equine encephalitis virus MagPlex toxin antibody camelid vaccine biodefense hydrogen exchange-mass spectrometry virus formatting Fc-domain half-life ischemia stroke MCAO single domain antibodies phage display intrabody intracellular antibody GTPase RHO BRET RAS chromobodies live-cell imaging compound screening cellular models single-domain antibody fragments molecular imaging molecular therapy nuclear imaging targeted fluorescence imaging intraoperative imaging Nanobody Single Domain Antibody Cancer Immunotherapy Imaging influenza influenza B virus hemagglutinin single domain antibody NanobodyTM yeast display epitope mapping GFP C. elegans development drosophila zebrafish targeted photodynamic therapy hepatocyte growth factor receptor HGFR c-Met Met VHH photosensitizer single-domain antibodies neurodegenerative diseases brain imaging blood-brain barrier delivery Aids HIV Llama Antibodies bi-specific VHH pepscan competition studies co-crystallisation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557147503321 |
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Rothbauer Ulrich
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nanomaterials for Biomedical and Biotechnological Applications
| Nanomaterials for Biomedical and Biotechnological Applications |
| Autore | Ferraro Angelo |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (266 p.) |
| Soggetto topico |
Technology: general issues
Biotechnology |
| Soggetto non controllato |
neurodegenerative disease
cerium oxide nanoparticles Parkinson's disease oxidative stress physicochemical properties blood-brain barrier synthesis methods magnetic driving magnetic nanoparticles actuation system drug targeting chitosan clay nanocomposite films papain covalent immobilization wine magnetic gels drug release magnetic hyperthermia magnetic lipogels supramolecular hydrogels self-assembly nanoparticle functionalization organic and inorganic nanoparticles ophthalmic applications clinical trials orthopedic nanomedicine nanomodified surfaces animal model immune response Chlorella vulgaris microwave-synthesized magnetite particles response surface methodology harvesting process optimization optimization economic analysis plant design and process engineering cubic particles COVID-19 nanotechnology vaccines sanitizers biosensors restricted access media nanofibers microfibers on-line extraction biological samples column-switching chromatography theranostic nanomaterials boron nitride neutron capture reaction nuclear medicine drug delivery antibiotics antimicrobial resistance gold nanoparticles ciprofloxacin Enterococcus faecalis liver and kidney infections colorectal cancer biomarkers cytotoxic medication genetic pathways epigenetic changes prognostic phytomedicine rheumatoid arthritis methotrexate anti-arthritic activity nanoemulsion hemocompatibility MTT assay stability studies |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585937903321 |
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Ferraro Angelo
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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