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Paediatric Formulation: Design and Development
| Paediatric Formulation: Design and Development |
| Autore | Denora Nunzio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (205 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
acceptable
administration age-related anakinra autoinflammatory disease bioavailability biopharmaceutics canakinumab child children chronic myeloid leukemia confocal microscopy cyclodextrin inclusion complex dasatinib design design of experiments development device dosage form drug delivery Duchenne muscular dystrophy edible films excipient flavor profile formulation formulation development grinding imatinib inhaled innovative biotechnologies Interleukin-1 intra nasal Kawasaki disease liquid formulation medication error modified release neglected tropical diseases neonates NICU nilotinb Norvir® oral Orodispersible formulation paediatric paediatric age paediatric dosage forms paediatric formulation development palatability assessment palatable parenteral pediatric pediatric age pediatric drug delivery pediatrics penetration personalized medicine phase solubility studies polymorph ponatinib poorly soluble compound poorly water soluble drug product development pyrazinamide retinoblastoma ritonavir solubility enhancement spray congealing systemic juvenile idiopathic arthritis taste-masking topical topotecan tuberculosis tumorspheres tyrosine kinase inhibitors |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Paediatric Formulation |
| Record Nr. | UNINA-9910557304003321 |
Denora Nunzio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation
| Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation |
| Autore | Gonzalez-Alvarez Maria Isabel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (238 p.) |
| Soggetto topico |
Manufacturing industries
Medicine and Nursing |
| Soggetto non controllato |
absorption-modifying excipients
BCS class IV drugs BCS drugs bioequivalence biomimetic membrane biopharmaceutics biopharmaceutics classification system Biopharmaceutics Classification System clinical studies colon absorption combined zero- and first-order absorption controlled release drug product DDI disintegration dissolution dissolution test drug absorption drug permeability drug solubility drug solubility/dissolution drug-drug interactions energy intake enteric-coated first-order absorption first-pass effect Franz cell Franz-PAMPA furosemide gastrointestinal gastrointestinal hormone GastroPlus hierarchical support vector regression (HSVR) human colon carcinoma cell layer (Caco-2) ibuprofen ICH in silico modeling in situ perfusion in vitro in vitro in vivo extrapolations intestinal absorption intestinal perfusion intestinal permeability IVIVE location-dependent absorption manometry mechanistic modeling microdevices mucoadhesion nutrient absorption nutrient digestion obesity oral absorption oral drug delivery oral peptide delivery passive drug transport PBBM PBPK permeation enhancers pharmaceutical development pharmacokinetics Phoenix WinNonlin physiologically-based pharmacokinetic (PBPK) modeling postprandial glycaemia pravastatin quality control region of the gut regional intestinal permeability regional/segmental-dependent permeability and absorption route-dependent intestinal metabolism segmental-dependent intestinal permeability segregated flow intestinal model (SFM) shape traditional model (TM) transit compartment absorption model type 2 diabetes zero-order absorption |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Regional Intestinal Drug Absorption |
| Record Nr. | UNINA-9910566462603321 |
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Gonzalez-Alvarez Maria Isabel
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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