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Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing
| Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing |
| Autore | Pörtner Ralf |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (226 p.) |
| Soggetto topico |
Technology: general issues
History of engineering & technology |
| Soggetto non controllato |
clonal cell population
phenotypic diversity inoculum train uncertainty-based cell culture model biopharmaceutical manufacturing Escherichia coli hybrid modeling machine learning model-assisted DoE quality by design upstream bioprocessing surface plasmon resonance (SPR) bioprocess monitoring biosensor quality by design (QbD) process analytical technology (PAT) biotherapeutics production vaccines production CHO DP-12 computational fluid dynamics bioreactor characterization hydrodynamic gradients process development critical shear stress Kolmogorov length scale operational space sensors cell culture spectroscopy PAT smart biomanufacturing soft-sensor Adeno-associated virus transfection PEI continuous gene therapy microcarriers bioreactor transient expression spheroid strength β-cells diabetes shear stress-guided production hydrodynamic stress Gaussian processes Bayes optimization Pareto optimization multi-objective seed train Chinese hamster ovary cells cryopreservation monoclonal antibodies N−1 perfusion process intensification upstream processing |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595072803321 |
Pörtner Ralf
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Expanding the Horizons of Manufacturing: Towards Wide Integration, Smart Systems and Tools
| Expanding the Horizons of Manufacturing: Towards Wide Integration, Smart Systems and Tools |
| Autore | Puigjaner Luis |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (446 p.) |
| Soggetto topico |
Technology: general issues
History of engineering & technology |
| Soggetto non controllato |
manufacturing process
additive manufacturing IoT computer systems and networks 3D printing digital twin Industry 4.0 pharmaceutical manufacturing biopharmaceutical manufacturing process modeling mixed-integer linear programming bin-packing problem material requirements planning agri-supply chain management variable production rate optimal resources imperfect production eco-efficient production closed-loop scheduling scheduling stability optimal control and scheduling fouling heat exchanger networks continuous manufacturing bioprocessing process systems engineering single-use technology AGV-Automated Guided Vehicles DES-Discrete Event Simulation FMS-Flexible Manufacturing Systems OEE-Overall Equipment Efficiency WCLcWorld Class Logistic abrasive water jet cutting surface quality quality prediction 3D simulation modeling and analysis model implementation bottleneck analysis production costs resource conservation smart manufacturing edge computing machine learning blockchain Industrial Internet of Things inventory management supply chain multi-echelon stochastic programming reinforcement learning digitalisation model-based computational engineering process simulation LNG terminal operational optimization BOG compressor MINLP enterprise process architecture new technologies integration process intelligence real-time monitoring fault detection predictive process adjustment vacuum gripper sensor data Tri-X Intelligence cyber-physical systems human-cyber systems intelligent systems intelligent manufacturing multi-parametric programming explicit MPC enterprise-wide optimisation set-point tracking algebraic geometry continuous pharmaceutical manufacturing model predictive control state estimation quality-by-control (QbC) glidant effects plant-model mismatch regional logistics low-carbon economy cloud model comprehensive evaluation Beijing-Tianjin-Hebei region pharmaceutical manufacture uncertainty operational flexibility operational envelopes modeling |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Expanding the Horizons of Manufacturing |
| Record Nr. | UNINA-9910585940603321 |
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Puigjaner Luis
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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