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Foundations of Theoretical Approaches in Systems Biology
| Foundations of Theoretical Approaches in Systems Biology |
| Autore | Julio Vera |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (216 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
Biotechnology
Synthetic Biology mathematical modeling Biochemical systems theory Systems Medicine computational modeling Systems Biology biological networks |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910345964803321 |
Julio Vera
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Identification and Characterization of Genetic Components in Autism Spectrum Disorders 2019
| Identification and Characterization of Genetic Components in Autism Spectrum Disorders 2019 |
| Autore | Butler Merlin G |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (256 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Genetics (non-medical) |
| Soggetto non controllato |
autism spectrum disorders (ASD)
cancer overlapping genes and gene profiling super-pathways phenotypes and diseases molecular functions and processes 15q11.2 BP1-BP2 microdeletion (Burnside-Butler) syndrome imprinting parent-of-origin effects phenotype-genotype correlation autism developmental delays motor delays microbiome gut ProSAP2 Phelan McDermid Syndrome gut–brain interaction leaky gut IL-6 SHANK collapsin response mediator protein 4 autism spectrum disorder neurodevelopmental disorder whole-exome sequencing animal model sex different phenotypes 15q11.2 BP1–BP2 microdeletion (Burnside–Butler syndrome) NIPA1 NIPA2 CYFIP1 TUBGCP5 genes Prader–Willi and Angelman syndromes magnesium transporters and supplementation potential treatment options intellectual disability AMPA receptors NMDA receptors guanine nucleotide exchange factor synaptic plasticity Autism spectrum disorder ASD Obesity Overweight Body mass index BMI autism candidate genes synaptotagmin-like protein 4 (SYTL4) transmembrane protein 187 (TMEM187) SYTL4-protein structure STRING-protein-protein interaction expression profile microRNA- interactions autism spectrum disorders biological networks genomics multi-omics network diffusion data integration genetics quantitative traits stratification by trait severity heterogeneity reduction case-control association analysis fragile X syndrome RNA toxicity DNA methylation mosaicism pediatrics MS-QMA AmplideX cytokine monocyte β-glucan T cell cytokine trained immunity maternal immune activation epigenetics mice postnatal VPA injection SAM gene expression nanostring |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566483203321 |
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Butler Merlin G
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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In Silico Strategies for Prospective Drug Repositionings
| In Silico Strategies for Prospective Drug Repositionings |
| Autore | Udrescu Lucreția |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
COVID-19
drug repurposing topological data analysis persistent Betti function SARS-CoV-2 network-based pharmacology combination therapy nucleoside GS-441524 fluoxetine synergy antidepressant natural compounds QSAR molecular docking drug repositioning UK Biobank vaccine LC-2/ad cell line drug discovery docking MM-GBSA calculation molecular dynamics cytotoxicity assay GWAS multiple sclerosis oxidative stress repurposing ADME-Tox bioinformatics complex network analysis modularity clustering ATC code hidradenitis suppurativa acne inversa transcriptome proteome comorbid disorder biomarker signaling pathway druggable gene drug-repositioning MEK inhibitor MM/GBSA Glide docking MD simulation MM/PBSA single-cell RNA sequencing pulmonary fibrosis biological networks p38α MAPK allosteric inhibitors in silico screening computer-aided drug discovery network analysis psychiatric disorders medications psychiatry mental disorders toxoplasmosis Toxoplasma gondii in vitro screening drug targets drug-disease interaction target-disease interaction DPP4 inhibitors lipid rafts |
| ISBN | 3-0365-6133-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639987703321 |
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Udrescu Lucreția
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Methods in Computational Biology
| Methods in Computational Biology |
| Autore | Carlson Ross |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (214 p.) |
| Soggetto non controllato |
inosine
immune checkpoint inhibitor geometric singular perturbation theory simulation BioModels Database ADAR calcium current bifurcation analysis bacterial biofilms nonlinear dynamics explanatory model turning point bifurcation oscillator workflow bioreactor integrated modeling modeling methods elementary flux modes visualization multiscale systems biology evolutionary algorithm metabolic model differential evolution reduced-order model computational model gut microbiota dysbiosis canard-induced EADs computational biology metabolic modelling methods SREBP-2 mechanistic model systems modeling biological networks macromolecular composition provenance flux balance analysis immunotherapy compartmental modeling immuno-oncology metabolic network visualization mechanism bistable switch Clostridium difficile infection bioreactor operation optimization microRNA targeting CFD simulation biomass reaction RNA editing ordinary differential equation metabolic modeling mass-action networks hybrid model multiple time scales quantitative systems pharmacology (QSP) mathematical modeling microRNA cancer parameter optimization Hopf bifurcation breast |
| ISBN | 3-03921-164-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346689103321 |
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Carlson Ross
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant-Microbe-Insect Interactions in Ecosystem Management and Agricultural Praxis
| Plant-Microbe-Insect Interactions in Ecosystem Management and Agricultural Praxis |
| Autore | Benckiser Gero |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (531 p.) |
| Soggetto topico |
Science: general issues
Botany & plant sciences |
| Soggetto non controllato |
biological networks
Species identification Metabolic reactions transmission Mutualistic symbiosis Systemic resistance agricultural management |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557243903321 |
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Benckiser Gero
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Impact of Systems Medicine on Human Health and Disease
| The Impact of Systems Medicine on Human Health and Disease |
| Autore | Adil Mardinoglu |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 electronic resource (96 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
Metabolic Networks and Pathways
Networks medicine Metabolic Diseases Systems Medicine Systems Biology biological networks |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910220038803321 |
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Adil Mardinoglu
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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