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A Themed Issue in Honor of Professor Raphael Mechoulam: The Father of Cannabinoid and Endocannabinoid Research
| A Themed Issue in Honor of Professor Raphael Mechoulam: The Father of Cannabinoid and Endocannabinoid Research |
| Autore | Maccarrone Mauro |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (236 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research and information: general |
| Soggetto non controllato |
4'-fluoro-cannabidiol
6-hydroxydopamine alcohol craving allodynia aminoalkylindole amyotrophic lateral sclerosis anandamide anti-CB1 antibody anti-inflammatory antinociception biased signaling cannabichromene cannabidiolic acid cannabidivarin cannabidivarinic acid cannabigerol cannabinoid cannabinoid receptor cannabinoid receptor 2 (CB2R) cannabinoid tetrad cannabinoids catalepsy CB1 CB1 receptor antagonist cholesterol chromenopyrazole CP55940 drinking in the dark elevated plus maze endocannabinoid equilibrative nucleoside transporter frontal cortex functional selectivity G-protein ghrelin GPR55 receptors gut microbiome hippocampus HUF-101 hybrid ligand inflammaging iNOS inhibitor intestine intracerebroventricular administration JWH-018 K2 LEAP2 lipofuscin lipopolysaccharide marble bury memory microglia MRI-1867 mSOD1 mice N-acyltransferase n/a obesity Parkinson's disease phospholipase A2 phytocannabinoids PPARs pravadoline rescue model rimonabant spice synaptosomes TDP-43 transgenic mice tetrahydrocannabivarin two-bottle paradigm type 1 cannabinoid receptor CB1 VCE-006.1 WIN55212-2 β-arrestin |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Themed Issue in Honor of Professor Raphael Mechoulam |
| Record Nr. | UNINA-9910566470103321 |
Maccarrone Mauro
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Monitoring endogenous GPCRs: lessons for drug design
| Monitoring endogenous GPCRs: lessons for drug design |
| Autore | Dominique Massotte |
| Pubbl/distr/stampa | Frontiers Media SA, 2015 |
| Descrizione fisica | 1 online resource (134 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Pharmacology |
| Soggetto non controllato |
biased signaling
cannabinoid receptors CGamP mice Endogenous receptors FLIM fluorescent knock-in mice G protein coupled receptors Opiate tolerance opioid receptors receptor heteromerization |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Monitoring endogenous GPCRs |
| Record Nr. | UNINA-9910137094503321 |
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Dominique Massotte
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| Frontiers Media SA, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery
| Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery |
| Autore | Spetea Mariana |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (358 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
(−)-N-phenethylnorhydromorphone analogs
[35S]GTPgammaS assay [Dmt1]DALDA 14-methoxycodeine-6-O-sulfate 1H-NMR experiments 6β-naltrexol abuse agonist allodynia analgesia analgesics antagonist arrestin recruitment beta-arrestin bias factor biased agonism biased agonist biased agonists biased ligands biased signaling bifunctional ligands binding binding affinity BNTX buprenorphine chronic constriction injury (CCI) codeine codeine-6-O-sulfate DADLE DALDA DAMGO delta opioid receptor dependence design and synthesis dihydrocodeine diphenethylamines docking dysbiosis fentanyl forskolin-induced cAMP accumulation assays functional assay G-protein bias heteromer hyperalgesia interaction fingerprints internalization inverse agonist ischemia kappa opioid receptor KGOP01 Leu-enkephalin loperamide lysosomes macrocyclic tetrapeptide mechanism elucidation misuse mitragynine molecular docking molecular dynamics molecular modeling & MOR and DOR agonists morphinan morphine mu opioid receptor mu receptor multifunctional ligands n/a naltrexone neonatal opioid withdrawal syndrome neurokinin-1 receptor neutral antagonist NTI derivative opioid opioid drugs opioid liabilities opioid peptide opioid peptides opioid peptides and peptidomimetics opioid receptors opioid side effects opioids over-the-counter drugs pain therapy partial agonism partial agonist peptide synthesis peripheral analgesic tolerance peripheral antinociception peripheral µ-opioid receptors pharmacology plasma stability potassium channels primary hippocampal culture PZM21 racemic synthesis of β2-amino acids receptor binding studies receptor model respiration respiratory depression selectivity simulation SR-17018 structure-activity relationships sulfonamide TAPP tolerance writhing test zerumbone β-arrestin recruitment assays β2-amino acids β2-Homo-amino acids δ opioid receptor δ opioid receptor antagonist μ opioid receptor µ opioid receptor µ-opioid receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Opioids and Their Receptors |
| Record Nr. | UNINA-9910557108003321 |
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Spetea Mariana
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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