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ABC Transporters in Human Diseases
| ABC Transporters in Human Diseases |
| Autore | Falguières Thomas |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (494 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
5' untranslated region
AAV ABC ABC (ATP-binding cassette) transporters ABC transporter ABC transporters ABCA subfamily ABCA7 ABCB1 ABCB11 ABCB4 ABCC2 ABCC6 ABCG2 ABCG2 genotype ABCG5 ABCG5/G8 ABCG8 adrenoleukodystrophy Alzheimer's disease amyloid-beta anticancer antifungal resistance atherosclerosis ATP-binding cassette transporter ATP-binding cassette transporter A1 (ABCA1) Aβ peptides BCRP beta-amyloid bile salts bile secretion bioinformatics blood-brain barrier breast cancer BRIC BSEP calcification cAMP cancer cellular ATP efflux chaperones cholesterol cholesterol homeostasis cis-acting elements clinico-genetic analysis competitive allele-specific PCR disease-free survival drug action drug transport dyslipidemia early-onset gout erlotinib ethnic specificity fatty acids functional divergence gall stone gene therapy generalized arterial calcification of infancy genetic variations gout HDL-C homology modeling hyperuricemia intracellular traffic intrahepatic cholestasis invasion MDR3 mechanism mechanism of action membrane protein microparticles migration molecular partners MRP1 MRP4 multidrug resistance multidrug transporter mutagenesis mutations n/a neuron next-generation sequencing NT5E P-glycoprotein peroxisome PET PFIC PFIC2 phagocytosis phosphatidylcholine phytosterol polar relay polymorphisms precision medicine proliferation pseudoxanthoma elasticum Pseudoxanthoma elasticum (PXE) pyrophosphate RAB GTPase rare variant regulatory extension regulatory insertion reverse cholesterol transport Roma serum uric acid single nucleotide polymorphism sitosterolemia SK-N-SH SNP SUA-lowering therapy substrate-binding site tariquidar taxol therapies therapy response TNAP trafficking transport transporter type 2 diabetes urate urate transporter uric acid xenosterol yeast |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674029103321 |
Falguières Thomas
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Identification of Multiple Targets in the Fight against Alzheimer's Disease
| Identification of Multiple Targets in the Fight against Alzheimer's Disease |
| Autore | Giannoni Patrizia |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (288 p.) |
| Soggetto topico |
Neurosciences
Science: general issues |
| Soggetto non controllato |
APP
beta-amyloid hormones inflammation microbiome multi-interventions neurovascular unit |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557478903321 |
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Giannoni Patrizia
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Biomarkers in Alzheimer's Disease
| Novel Biomarkers in Alzheimer's Disease |
| Autore | Villa Chiara |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (442 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
(18F)FDG
adipose tissue dysfunction ageing aging Alzheimer disease Alzheimer's disease Alzheimer's disease (AD) amyloid amyloid beta Amyloid Beta amyloid beta peptide amyloid cascade hypothesis antioxidant ApoE APOE APOE alleles APP mutations bacteria behavioral and psychological symptoms of dementia (BPSD) beta-amyloid biofluids biomarker biomarkers blood cardiovascular risk factors carotenoids CART analysis cerebrospinal fluid clinical trials Clock clock genes cognition cognitive decline COMT cytokines dementia diabetes diagnosis diagnostic research diagnostics drug development early diagnosis early onset AD EEG endophenotypes energetic metabolism episodic memory exosomes familial AD flotillin genetic variants genetics of AD germline mutations glucose metabolism glycolytic reserve inflammation late onset AD lysosomes dysfunction membrane potential messenger RNA metabolomics microRNA mild cognitive impairment mitochondrial mitochondrial dysfunction mitochondrial spare respiratory capacity MTHFR Multiplex multivariate analysis n/a neurodegeneration neurofilament light chain neuroimaging neuroinflammation neuropsychiatry inventory scale (NPI) neuropsychological assessment neuropsychology neurotropic microbes NfL nutrition obesity older adults omega-3 fatty acids person-tailored PET/CT phonemic fluency phosphorylated tau physical performance precision medicine prognostics PSEN1 PSEN2 semantic memory semantic priming SiMoA soluble TREM2 subjective cognitive decline synaptic biomarkers tau Tau TMS total tau Type-3-Diabetes virus vitamin E |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557129403321 |
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Villa Chiara
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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