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ABC Transporters in Human Diseases
| ABC Transporters in Human Diseases |
| Autore | Falguières Thomas |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (494 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
ABC transporters
drug action regulatory extension regulatory insertion mechanism of action MRP1 MRP4 breast cancer proliferation migration invasion cAMP ABCG2 ABCB1 blood-brain barrier PET Alzheimer's disease beta-amyloid tariquidar erlotinib ABCG5 ABCG8 ATP-binding cassette transporter cholesterol polar relay sitosterolemia 5' untranslated region cis-acting elements ABCA subfamily bioinformatics ABC transporter therapy response disease-free survival next-generation sequencing competitive allele-specific PCR P-glycoprotein amyloid-beta neuron SK-N-SH gene therapy AAV PFIC BSEP ABCB11 bile salts intrahepatic cholestasis chaperones PFIC2 BRIC ATP-binding cassette transporter A1 (ABCA1) cholesterol homeostasis reverse cholesterol transport HDL-C dyslipidemia type 2 diabetes microparticles ABCG2 genotype clinico-genetic analysis ethnic specificity genetic variations precision medicine rare variant Roma serum uric acid SUA-lowering therapy urate transporter bile secretion ABCB4 ABCC2 ABCG5/G8 molecular partners phytosterol xenosterol atherosclerosis gall stone ABC transporter ABC (ATP-binding cassette) transporters multidrug resistance transport trafficking urate mutations polymorphisms ABCC6 TNAP NT5E Pseudoxanthoma elasticum (PXE) cancer membrane protein functional divergence calcification pseudoxanthoma elasticum generalized arterial calcification of infancy pyrophosphate therapies ABCA7 phagocytosis Aβ peptides yeast multidrug transporter anticancer antifungal resistance mechanism peroxisome adrenoleukodystrophy fatty acids gout early-onset gout hyperuricemia uric acid BCRP single nucleotide polymorphism SNP homology modeling substrate-binding site cellular ATP efflux mutagenesis intracellular traffic MDR3 phosphatidylcholine RAB GTPase taxol drug transport |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674029103321 |
Falguières Thomas
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Identification of Multiple Targets in the Fight against Alzheimer’s Disease
| Identification of Multiple Targets in the Fight against Alzheimer’s Disease |
| Autore | Giannoni Patrizia |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Science: general issues
Neurosciences |
| Soggetto non controllato |
inflammation
multi-interventions neurovascular unit microbiome hormones APP beta-amyloid |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557478903321 |
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Giannoni Patrizia
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Biomarkers in Alzheimer's Disease
| Novel Biomarkers in Alzheimer's Disease |
| Autore | Villa Chiara |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (442 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
flotillin
Alzheimer's disease biomarker exosomes beta-amyloid Tau aging biomarkers cytokines cognitive decline metabolomics neuroinflammation multivariate analysis physical performance person-tailored PET/CT (18F)FDG neuropsychological assessment APP mutations APOE alleles PSEN1 PSEN2 germline mutations late onset AD early onset AD familial AD genetics of AD mitochondrial spare respiratory capacity mitochondrial membrane potential glycolytic reserve semantic memory phonemic fluency episodic memory neuropsychology neuroimaging mild cognitive impairment EEG TMS obesity diabetes inflammation Amyloid Beta mitochondrial dysfunction nutrition omega-3 fatty acids antioxidant carotenoids vitamin E cognition older adults ageing subjective cognitive decline clock genes Clock ApoE cardiovascular risk factors Alzheimer disease semantic priming amyloid beta cerebrospinal fluid amyloid beta peptide total tau phosphorylated tau diagnosis drug development clinical trials diagnostic research virus bacteria dementia blood behavioral and psychological symptoms of dementia (BPSD) Alzheimer's disease (AD) neuropsychiatry inventory scale (NPI) endophenotypes CART analysis MTHFR APOE COMT genetic variants early diagnosis biofluids amyloid cascade hypothesis glucose metabolism adipose tissue dysfunction energetic metabolism lysosomes dysfunction Type-3-Diabetes neurodegeneration amyloid tau soluble TREM2 NfL Multiplex SiMoA diagnostics messenger RNA microRNA neurotropic microbes precision medicine prognostics synaptic biomarkers neurofilament light chain |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557129403321 |
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Villa Chiara
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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