A Meeting of Minds: In Recognition of the Contributions of Randall J. Cohrs |
Autore | Grose Charles |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (424 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
varicella-zoster virus
Oka strain human herpesvirus 6 human herpesvirus 7 corticosteroids serious adverse event herpes zoster IL-6 IL-10 innate immunity VLT VLT-ORF63 CRISPR/Cas9 BAC mutagenesis flavivirus SARS-CoV-2 pandemic preparedness host-virus interactions prion vaccines interferon lambda virus herpes simplex virus type 1 herpes simplex virus type 2 neonatal herpesvirus infection HSV UL6 herpesvirus encephalitis herpesvirus hepatitis acyclovir HerpeSelect test viral sequencing HELLP syndrome lipids dengue virus acyl-CoA acyl-CoA thioesterase fatty acids membranes rheostat fatty acyl-CoA Marek's disease virus live-cell genome visualization lytic replication T cells latency genome integration TetO/TetR system varicella zoster virus reactivation genome cleavage AAV antiviral therapies HSV-1 cornea trigeminal ganglia interferon-γ interferon stimulatory genes TRIM21 HSV EBV KSHV MHV68 PIC transcription productive elongation mRNA rRNA tRNA herpes viral reactivation spaceflight dermatitis stress immune depression antiviral drugs bacterial artificial chromosome luciferase bioluminescence imaging skin organ culture humanized mice β-Coronavirus mouse hepatitis virus-A59/MHV-A59 mouse hepatitis virus-2/MHV2 spike protein fusion peptide/FP cell-to-cell fusion (fusogenicity) neuropathogenesis hepatitis demyelination structural rigidity simian varicella virus herpesvirus varicella VZV neuro-attenuated ORF7 vaccine antiviral COVID-19 drug discovery coronavirus spike protein Mpro RdRp PLpro skin epidermis keratinocytes epidermal differentiation cutaneous blistering lesions keratins autophagy immunity human neuron culture non-coding RNA CD8 T cell T-cell epitope NK cell KIR3DL1 HLA-B*57:01 herpes simplex virus zoster skin pathogenesis HSV-2 neurons cell culture varicella-zoster gene expression ganglion autopsy saliva salivary VZV DNA dengue viruses Aedes aegypti adaptive mutation |
ISBN | 3-0365-5260-X |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Meeting of Minds |
Record Nr. | UNINA-9910619471403321 |
Grose Charles
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MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
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Lo trovi qui: Univ. Federico II | ||
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Advances in the Treatment of Renal Cell Carcinoma |
Autore | Reynolds Paul |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (221 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
renal cell carcinoma
autophagy hydroxychloroquine chloroquine ROC-325 cysteine cathepsins cysteine cathepsin inhibitors lysosome renal cancer metastatic renal cell carcinoma immune-based combination therapies network meta-analysis PD-L1 predictive biomarker treatment TKIs mRCC biomarkers soluble factors immunotherapy renal cell carcinoma (RCC) sunitib resistance artesunate (ART) Traditional Chinese Medicine (TCM) growth inhibition ferroptosis reactive oxygen species (ROS) clear cell renal cell carcinoma ccRCC RCC kidney cancer evolution evolutionary trajectory metastatic second line therapy renal cell cancer immune checkpoint inhibitors tyrosine kinase inhibitors individualization genomic signature transcriptomic analysis |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557615503321 |
Reynolds Paul
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Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
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Lo trovi qui: Univ. Federico II | ||
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Advances in Transmission Electron Microscopy for the Study of Soft and Hard Matter |
Autore | Carlino Elvio |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (134 p.) |
Soggetto topico |
Technology: general issues
History of engineering & technology Materials science |
Soggetto non controllato |
scanning transmission electron microscopy (STEM)
electron tomography (ET) sparse imaging inpainting reconstruction biological samples Trypanosoma brucei TEM in-line holography single particle imaging atomic resolution imaging radiation damage soft matter nanostructured drugs organic materials holography electron holography diffraction coherent diffraction imaging iterative phase retrieval biomolecules propionic acid autophagy mitophagy correlative light and electron microscopy (CLEM) amorphous silica powder diffraction transmission electron microscopy high-resolution spectroscopy electron diffraction electron pair distribution function magnetic nanoparticles magnetic hyperthermia EMCD EELS magnetism acceleration voltage |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910566471103321 |
Carlino Elvio
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Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
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Lo trovi qui: Univ. Federico II | ||
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AMP-Activated Protein Kinase Signalling |
Autore | Neumann Dietbert |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
Descrizione fisica | 1 electronic resource (452 p.) |
Soggetto non controllato |
HDACs
transcription epigenetics spermatozoa par complex A769662 MDCK skeletal muscle AID phosphorylation energy metabolism monocytes autophagy CML liver hindlimb suspension pregnancy preeclampsia gestational diabetes mellitus CaMKK2 assisted reproduction techniques nutrient-sensing signals sonic hedgehog protein acetylation glycogen storage disease AMPK adenosine monophosphate-activated protein kinase AICAR indirect calorimetry IL-1? MyHC I(?) HDAC4/5 endothelial cells infection hepatocyte p70S6K lipid metabolism host defense exercise kidney disease heat shock protein ?RIM mycobacteria activation loop developmental origins of health and disease (DOHaD) CREB TAK1 metabolic-inflammation phenylephrine AMP-activated protein kinase (AMPK) KATs 2-methoxyestradiol DNA methylation NLRP3 pump ?-linker steatosis AMPK kinase stress endothelial nitric-oxide synthase vasodilation adherent junctions epithelial cells glycogen Akt synaptic activation cellular energy sensing glucose uptake transporter co-expression atrophy nutrigenomics motility vasoconstriction fatty acid oxidation oxidative stress AS160 membrane histone modification sirtuin 1 (SIRT1) chromatin remodeling insulin signalling dietary fatty acids ULK CMML adaptive thermogenesis mTOR MDS mechanical unloading AML endothelial function medulloblastoma PKA adipose tissue NAD+ membranes nutrition ZO-1 TBC1D4 adipocyte soluble Adenylyl cyclase metabolism renin-angiotensin system energy utilization proteasome differentiation signaling peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) hypertrophy AMP-activated protein kinase metabolic disease LKB1 soleus muscle macrophages Immediate early genes CBS benign motor endplate remodeling ionomycin nectin-afadin tight junctions resveratrol protein kinase B regrowth mitochondria protein synthesis energy deficiency catechol-O-methyltransferase fiber-type microarrays carrier acetyl-CoA hypertension 3T3-L1 hypothalamus food intake |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910346858503321 |
Neumann Dietbert
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MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
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Lo trovi qui: Univ. Federico II | ||
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Anticancer Inhibitors |
Autore | Fantacuzzi Marialuigia |
Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
Descrizione fisica | 1 electronic resource (216 p.) |
Soggetto topico |
Research & information: general
Chemistry |
Soggetto non controllato |
breast cancer
tamoxifen LY294002 synergism apoptosis cell cycle tea (Camellia sinensis) flowers BTFS A2780/CP70 ovarian cancer cells S phase cell cycle arrest nicotinamide phosphoribosyltransferase NAD+ biosynthesis inhibitor azacyclohexane anticancer drug drug design enthalpy effect NSCLC Cathepsin K cell proliferation cell migration cell invasion mTOR isatin-hydrazones cytotoxicity CDK2 inhibitor ATP competitive inhibitor ADME analysis receptor tyrosine kinases protein-protein interactions protein engineering directed evolution angiogenesis binding affinity agonistic activity saponins phytochemicals tea (Camellia sinensis) flower ovarian cancer autophagy ZMYND8 tumorigenesis epigenetic regulation pro-oncogenic effects tumor suppression tacrine-coumarin derivatives DNA topoisomerases I, II lung carcinoma cells A549 chemotherapy prodrug drug targeting overexpressed enzymes ADC ADEPT GDEPT LEAPT PROTAC cyclin-dependent kinase cancer resistance small molecule inhibitors PROTACs statins pancreatic cancer DNA microarray pitavastatin cerivastatin simvastatin fluvastatin atorvastatin pravastatin HMG-CoA reductase inhibitors |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910595069203321 |
Fantacuzzi Marialuigia
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Basel, : MDPI Books, 2022 | ||
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Lo trovi qui: Univ. Federico II | ||
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Anticancer Properties of Natural and Derivative Products |
Autore | Lupiáñez José Antonio |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (312 p.) |
Soggetto topico | Research & information: general |
Soggetto non controllato |
total phenolic content
total flavonoid content GC-MS DPPH antioxidant anticancer agent anti-inflammatory agent gingival fibroblasts oral cancer natural extract Adenosma bracteosum extract anti-cancer cell line isolated compounds caspase-3 bioactive compounds metabolites wine grapes breast cancer chemoprevention chemotherapy squamous cell carcinoma Moringa oleifera 3-hydroxy-β-ionone antioxidant activity antioxidant enzymes anti-proliferative activity maslinic acid melanoma Olea europaea L. ROS levels photodynamic therapy cancer photosensitiser natural compounds Elaeagnus angustifolia EMT apoptosis AKT/PI3K signaling pathway human hepatocarcinoma HepG2 cells migration activity proliferation oxidative stress ROS level uvaol lung metastases in vivo complementary medicine medicinal mushrooms triterpenoic acid tormentic acid betulinic acid oleanolic acid rhodamine B cytotoxicity hepatocellular carcinoma (HCC) Pogostemon cablin (PPa extract) cell cycle synergism natural photosensitive compounds anticancer activity hypericin emodin quinizarin danthron interaction DNA glioblastoma (GBM) lactucopicrin (LCTP) temozolomide (TMZ) autophagy NF-κB p62/SQSM1 natural product therapeutic triglyceride xenograft study Caveolin-1 actin cytoskeleton betulin glycoconjugates click chemistry 1,3-dipolar cycloaddition |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557370303321 |
Lupiáñez José Antonio
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Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
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Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products |
Autore | Fabiani Roberto |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (344 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557419703321 |
Fabiani Roberto
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Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
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Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products : Volume 2 |
Autore | Fabiani Roberto |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (300 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Antitumoral Properties of Natural Products |
Record Nr. | UNINA-9910557531303321 |
Fabiani Roberto
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Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
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Lo trovi qui: Univ. Federico II | ||
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Autophagy in Autoimmunity |
Autore | Zhou Xu-jie |
Pubbl/distr/stampa | Frontiers Media SA, 2019 |
Descrizione fisica | 1 electronic resource (161 p.) |
Soggetto topico |
Medicine
Immunology |
Soggetto non controllato |
animal model
autoimmunity autophagy genetics human disease translational research therapy |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557236403321 |
Zhou Xu-jie
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Frontiers Media SA, 2019 | ||
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Lo trovi qui: Univ. Federico II | ||
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Autophagy in Endocrine-metabolic Diseases Associated with Aging |
Autore | Ines Vaccaro Maria |
Pubbl/distr/stampa | Frontiers Media SA, 2020 |
Descrizione fisica | 1 electronic resource (142 p.) |
Soggetto topico |
Medicine
Endocrinology |
Soggetto non controllato |
autophagy
autophagy (macroautophagy) chaperon mediated autophagy (CMA) secretory autophagy aging diabetes mellitus cancer skeletal muscle atrophy |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557665603321 |
Ines Vaccaro Maria
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Frontiers Media SA, 2020 | ||
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Lo trovi qui: Univ. Federico II | ||
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