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Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0
| Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0 |
| Autore | Dansette Patrick M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (286 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
Antibiotics
Bacillus biosynthetic gene clusters comparative analysis cytochrome P450 monooxygenase Mycobacterium P450 diversity percentage P450 profiling secondary metabolites NADPH-cytochrome P450 reductase (CPR) microsomal cytochrome P450 (CYP) Cytochrome b5 (CYB5) protein dynamics electron-transfer (ET) protein–protein interaction cytochromes P450 CYP3A4 active site access channels cavities boundaries minimal cost paths CYP139A1 genome data mining host metabolism Mycobacterium tuberculosis polyketides tuberculosis cryptococcus cryptococcus neoformans CYP51 fungal pathogens genome data-mining human pathogens CYP diversity analysis tremellomycetes trichosporon mechanism-based inhibitor crystal structure CYP4 genes genetic polymorphisms 20-HETE fatty acid arachidonic acid SNPs molecular functionality metabolism lamellar ichthyosis Bietti’s crystalline dystrophy cytochrome P450 isoform membrane protein protein-membrane interactions enzyme substrate specificity mutagenesis molecular dynamics simulation Sogatella furcifera sulfoxaflor transcriptome RNA interference CYP2C8 polymorphisms reactive oxygen species paclitaxel cytochrome P450 reductase electron transfer extracellular vesicles exosomes extrahepatic tissues plasma circulatory CYPs CYP450 drug metabolism precision Cardio-Oncology precision medicine systems medicine cytochromes P450 monooxygenases Cyanobacteria gene-cluster diversity percentage mathematical formula phylogenetic analysis Streptomyces cytochrome P450 monooxygenases terpenes P450 blooming non-ribosomal peptides cytochrome P450 monooxygenenases CYP128A1 Mycobacterium tuberculosis H37Rv molecular dynamic simulations azole drugs menaquinone |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cytochromes P450 |
| Record Nr. | UNINA-9910557761103321 |
Dansette Patrick M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Diet and Immune Function
| Diet and Immune Function |
| Autore | Childs Caroline E |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (314 p.) |
| Soggetto non controllato |
immunonutrition
supplementation superoxide dismutase (SOD) fermented milk selenocysteine dendritic cells lipoxygenase (LOX) chronic inflammatory conditions formulation immune system cytokines skeletal muscle zinc non-digestible carbohydrates Toll-like receptor carbohydrates fiber lymphocytes antibody infants liver macrophage inflammatory process probiotic plant older people gut barrier infection amino acids gut T helper 1 (Th1) immunity T cells bioactive peptide inhibitor of kappa kinase (IKK) inflammation adhesion molecules leukocytes human milk oligosaccharides vitamin D food structure vitamin E mitogen-activated protein Kinase (MAPK) gut microbiota weaning homeostasis intestinal immune system extra-cellular signal regulated kinases (ERK) cyclooxygenase (COX) oxidative stress life course polyphenols oligosaccharides micronutrients Th17 obesity tolerance arachidonic acid growth factors anti-inflammation age-related immunity prebiotic biomarker microbiome functional foods immunosenescence nutrition molecular mechanisms metabolism macronutrients toll-like receptor 4 sepsis nutrition guidelines microbiota immunomodulation inflammatory markers elderly Th1/Th17 response adults reactive oxygen species (ROS) anorexia nervosa macrophages autoimmune diseases fatty acids T cell Treg breast milk nitric oxide synthase (NOS) chemokines anti-tumorigenic metabolites deficiency protein hydrolysate nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) cancer |
| ISBN | 3-03921-613-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404080503321 |
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Childs Caroline E
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Fatty Acids and Cardiometabolic Health
| Fatty Acids and Cardiometabolic Health |
| Autore | Wu Jason |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto non controllato |
coronary artery disease
n-6 fatty acids ischemic heart disease n-3 fatty acids body weight alternatively activated macrophages type 2 cytokines children medium-chain triglyceride fat omega-3 PUFA substitution models obesity EETs arachidonic acid blood pressure Genome-wide association study (GWAS) antioxidant Mediterranean diet Insulin sensitivity PUFA n-3 PUFA long-chain triglyceride fish oil omega 3 CAD adipose tissue FADS blood lipids hemodynamics genotype erucic acid klotho CYP450 eicosanoids cardiometabolic disease fibrosis desaturase EEQs cohort study lipid metabolism fatty acid metabolic disease epidemiology omega-3 inflammation docosapentaenoic acid omega-6 PUFA type 2 diabetes mellitus diet CKD human perivascular adipose tissue seafood cardiovascular disease prospective cohort study linoleic acid low-fat diet conjugated fatty acids furan fatty acids unsaturated fat statins fish cholesterol ester CHD COPD |
| ISBN | 3-03897-891-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346838103321 |
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Wu Jason
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Fungi and Fungal Metabolites for the Improvement of Human and Animal Nutrition and Health
| Fungi and Fungal Metabolites for the Improvement of Human and Animal Nutrition and Health |
| Autore | Dufossé Laurent |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (459 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
fungal pigment
natural dye spalting Scytalidium cuboideum dramada sustainable clothing selenium biofortification transporters mycorrhizal fungi plant growth-promoting rhizobacteria (PGPRs) fungal pigments textile dyeing toxicity testing biotechnological approaches challenges limits Saccharomyces boulardii Saccharomyces cerevisiae probiotics gastrointestinal tract Alginate β-glucan oligosaccharides elicitation Sargassum species Sparassis latifolia polyphenol antioxidant agave mezcalero bagasse apple bagasse solid-state fermentation secondary metabolites Pleurotus ostreatus Endophytic fungi Hyptis dilatata Pestalotiopsis mangiferae Pestalotiopsis microspora chemical elicitors antibacterial activity LC–ESI–Q–TOF–MS yeast biological control postharvest decay fruit mycorrhizae elevated CO2 Thymus vulgare growth photosynthesis metabolites biological activity Candida albicans non-albicans Candida species Candida auris aromatic alcohols fungi metabolomics NTCD additives functional foods nutraceuticals sustainability healthy aging Mortierella alpina animal fat by-product arachidonic acid ATR-FTIR spectroscopy Mucor circinelloides high-throughput screening metal ions phosphorus lipids biofuel FTIR spectroscopy bioremediation co-production natural colorants filamentous fungi stirred-tank bioreactor biodegradable films food package bioactive compounds FIP human health immunomodulation induced apoptosis lectin medicinal mushrooms polysaccharide terpenes and terpenoids melanin carotenoids polyketides azaphilones antitumor medical roles sphinganine-analog mycotoxins fumonisins AAL-toxin chemical structure toxicity genetics and evolution biosynthesis livestock ewes energy cytokines yeasts liquid swine diets MALDI-TOF biochemical identification growth temperature Ancom Gas Production System Candida krusei Candida lambica M. purpureus red yeast rice cholesterol reduction probiotic potential natural colorant extraction ability marine fungi Talaromyces albobiverticillius aqueous two-phases system extraction ionic liquids feed additive probiotic Sporidiobolus ruineniae tannase micro-fungi macro-fungi Ganoderma kombucha anticancer carotenoid medicinal mushroom mycobiome antimicrobial antifungal bioconversion cheese dairy Sclerotinia secondary metabolite endophytic fungi uncommon secondary metabolites |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557507403321 |
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Dufossé Laurent
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Kidney Inflammation, Injury and Regeneration
| Kidney Inflammation, Injury and Regeneration |
| Autore | Koch Benjamin |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (496 p.) |
| Soggetto non controllato |
microRNAs
transcription ischemia/reperfusion injury DSS-colitis kidney inflammation therapeutics targets CXCL13 glomerulus interleukin-6 rhabdomyolysis IgA nephropathy CREB Regulated Transcriptional Coactivators (CRTC) slit diaphragm injury xanthine oxidase Salt Inducible Kinase (SIK) acute and chronic kidney disease therapeutic target KIT-IgA score G-protein-coupled bile acid receptor (TGR5) lysophosphatidic acid glomerular injury IL-18 mesenchymal stem cells Taiwan acute kidney injury renal ischemia-reperfusion long non-coding RNA fibrosis acute kidney failure diabetic kidney diseases chronic kidney disease lncRNA LPS-binding protein endotoxemia-induced oliguric kidney injury dapagliflozin cPLA2 and COX-2 NLRP3 inflammasome CmklR1 haem chronic kidney injury omega-3 fatty acid noninvasive inflammation regulated necrosis GLP-1 receptor agonists miRNA AKI SGLT2 inhibitors diabetic kidney disease extracellular vesicles podocin type IV collagen epithelial cells nephrin 2-kidney-1-clip renal fibrosis papilla diagnostics necrosis non-coding RNAs podocyte Thy1.1 nephritis KIT assay oxidative stress conditioned medium C-reactive protein pericyte myofibroblast Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-?B) endotoxemia modifier gene polymorphism renal stem cells kidney polyploidization Class IIa Histone Deacetylases (HDAC) 2k1c molecular signaling proximal tubule arachidonic acid empagliflozin tubular injury signaling cascade signal transduction inflammatory maker niches biomarkers renal progenitors type V collagen cyclooxygenase focal segmental glomerulosclerosis inflammatory bowel disease (IBD) chronic kidney disease (CKD) allograft rejection renovascular hypertension genotype molecular mechanisms ROS prediction glomerular filtration barrier (GFB) alport syndrome scattered tubular cells long non-coding RNAs renal inflammation lysophosphatidic acid receptor cAMP Regulatory Element Binding Protein (CREB) Farnesiferol B differentiation mesenchymal stromal cells modified-MSCs kidney transplantation polyunsaturated fatty acids apoptosis type I collagen diabetes mellitus natural products lipoxygenase stem cell T cell-mediated rejection exosomes renal injury obese kidney fibrosis kidney injury cytotoxicity mesenchymal stem cell pigment nephropathy mesodermal stem cell ischemia-reperfusion cytochrome P450 renal cell carcinoma hematuria B-cell attracting chemokine microRNA chemerin glomerular basement membrane glomerular damage renal tubular cells kidney proximal tubule exosome hypertension diabetic nephropathy |
| ISBN | 3-03928-539-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404091203321 |
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Koch Benjamin
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metabolism and Metabolomics of Liver in Health and Disease
| Metabolism and Metabolomics of Liver in Health and Disease |
| Autore | Wahli Walter |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (268 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
nonalcoholic fatty liver disease
nonalcoholic steatohepatitis Fibrosis Liver biopsy Genomics Metabolomics Proteomics Transcriptomics nicotinamide NAFLD steatosis heat stress primary mouse hepatocytes metabolic profile GC-MS multivariate statistical analysis arachidonic acid docosahexaenoic acid inflammation fibrosis lipidomics mass spectrometry in vitro HepaRG sodium saccharin reference toxicants de novo lipogenesis carbohydrate response element-binding protein ChREBP diabetes glucose production glycogen glycolysis glycogen storage disease type I hexosamine pentose phosphate pathway acupuncture imflammation lipid metabolism oxidative stress metabolomics quantitative profiling 1H-NMR spectroscopy liver bile acids metabolomics rat plasma tandem mass spectrometry liquid chromatography acetaminophen hepatotoxicity biomarker premalignant alcoholic liver disease cholestasis cirrhosis NAFL NASH standard operating procedures urine blood feces tissue cells liver function nonalcoholic fatty liver liquid chromatography-mass spectrometry nuclear magnetic resonance spectroscopy metabolic pathway non-alcoholic fatty liver disease non-alcoholic steatohepatitis transcription factors metabolic stress lipid homeostasis glucose homeostasis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557148103321 |
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Wahli Walter
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metabolomic Applications in Animal Science
| Metabolomic Applications in Animal Science |
| Autore | Tomonaga Shozo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (265 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Technology, engineering, agriculture |
| Soggetto non controllato |
albumen
breed chicken feed metabolome yolk arachidonic acid omega-3 fatty acids lipidomics mass spectrometry dietary fat fatty acid metabolism pork meat skeletal muscle fiber type cooking beef Wagyu Holstein captive giraffes urine metabolomics 1H-NMR NMR metabotype transition ketosis cattle chemometrics spectral correction authentication biomarker feeding meat quality traits metabolite postmortem aging processing chickens heat stress lipid peroxidation orotic acid feed efficiency biomarkers SNPs GWAS RFI pigs pathways metabolic profile transition period livestock methyl donor one-carbon metabolism negative energy balance pasture legumes phytoestrogens flavonoids coumestans polyphenols proanthocyanidins metabolic profiling biosynthesis linear model transcriptomics horse metabolomic metabolism exercise saliva anabolic practices testosterone plasma CE-TOFMS intramuscular fat meat quality porcine |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557407903321 |
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Tomonaga Shozo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutrition, Exercise, and End-of-Life Discussion in the Cardiovascular Field
| Nutrition, Exercise, and End-of-Life Discussion in the Cardiovascular Field |
| Autore | Fukumoto Yoshihiro |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (194 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
milk intake
mortality stroke Bayesian survival analysis time-to-event data JACC study unhealthy eating habits accumulation obesity central obesity general Japanese population atherosclerotic cardiovascular disease polyunsaturated fatty acids eicosapentaenoic acid docosahexaenoic acid arachidonic acid descriptive study heart failure vitamin D big data heart failure with preserved ejection fraction geriatric nutritional risk index behavioral modification stages nutrition counseling patient education acute coronary syndrome healthy behaviors diet legumes fish red/processed meat physical activity anxiety depression season calorie intake hospitalization malnutrition D-dimer intervention elderly cardiovascular mortality selenium coenzyme Q10 acylcarnitine brain natriuretic peptide cardiac function cardiomyopathy carnitine deficiency CPT2 end-stage kidney disease free fatty acid hemodialysis continuous glucose monitoring glucose fluctuation intracranial artery stenosis mean amplitude of glycemic excursions standard deviation palliative care end-of-life care discussion advance care planning food intake artificial nutrition onco-cardiology nutrition status cancer acute myocardial infarction plant-based dietary patterns grains nuts fruits vegetables cardiovascular disease |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576885403321 |
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Fukumoto Yoshihiro
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Phospholipases: From Structure to Biological Function
| Phospholipases: From Structure to Biological Function |
| Autore | Balboa María A |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (348 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
inhibitor
metabolic stability α-methylation oxoesters phospholipase A2 adrenic acid arachidonic acid mass spectrometry lipid signaling inflammation monocytes/macrophages crotoxin snake venom lung impairment inflammatory response lipid mediators neuromuscular blocker lipidomics PAP-2 autotaxin lysophosphatidate G protein-coupled receptor PLA2G6 fatty liver phospholipid remodeling diet-induced obesity morbidly obesity choline and methionine deficiency glioblastoma sphingolipid sphingosine-1-phosphate sphingomyelinase sphingomyelin metastasis phosphatidic acid diacylglycerol lipin signaling cPLA2α psoriasis proliferation anti-inflammatory atherosclerosis phospholipases macrophages T cells lipins pancreatic islets β-cells insulin secretion glucose tolerance insulin resistance group VIA phospholipase A2 fatty acid knockout mouse lipid mediator lysophospholipid membrane phospholipid ceramide acidic sphingomyelinase neutral sphingomyelinase hepatocellular carcinoma alcoholic and nonalcoholic steatohepatitis preadipocytes prostaglandins adipokines cytokines EP receptors Group V phospholipase A2 lipids majeed syndrome LPIN2 LIPIN2 chronic non-bacterial osteomyelitis chronic recurrent multifocal osteomyelitis autoinflammatory inflammasome macrophage osteoclast |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Phospholipases |
| Record Nr. | UNINA-9910576879603321 |
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Balboa María A
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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