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Actinobacteria and Myxobacteria : Important Resources for Novel Antibiotics
| Actinobacteria and Myxobacteria : Important Resources for Novel Antibiotics |
| Autore | Wink Joachim |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (270 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
actinomycetes
antibiotic biosynthesis silent biosynthetic pathways γ-butyrolactones HiTES translation inhibitors marine actinobacteria Streptomyces sp enzyme inhibition antimicrobial antioxidant cytotoxicity GC-MS pyrrolopyrazines myxobacteria antivirals secondary metabolites HIV Ebola hepatitis viruses diversity uncultured new antibiotics Streptomyces polyketides secondary metabolite polyketide synthases (PKSs) |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Actinobacteria and Myxobacteria |
| Record Nr. | UNINA-9910557422303321 |
Wink Joachim
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Parvovirus Research 2020
| Advances in Parvovirus Research 2020 |
| Autore | Gallinella Giorgio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (258 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
feline parvovirus
virus-like particles VP2 protein antibodies AAV neuro-degenerative disease gene therapy antigenicity sequencing virus canine parvovirus peri-urban wild dogs disease transmission Australia parvovirus B19 G-quadruplex bioinformatics antivirals BRACO-19 pyridostatin oncolytic viruses rodent protoparvovirus H-1PV virus entry clathrin-mediated endocytosis parvovirus minute virus of mice RNA processing gene expression canine COVID-19 veterinary epidemiology B19V VP1u receptor PLA2 erythroid cells biomarker drug delivery nanocarrier B19 parvovirus detection cell cycle permissivity serotype capsid cryo-EM genome packaging gene delivery bocavirus Caribbean region new CPV-2a outbreak endemic nearly complete genomes virus evolution parvoviruses nucleus imaging of viral interactions and dynamics analysis of protein–protein interactions analysis of virus–chromatin interactions AMDV Aleutian disease mink parvovirus Aleutian mink disease virus vaccine |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557370403321 |
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Gallinella Giorgio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antivirals for Emerging Viruses: Vaccines and Therapeutics
| Antivirals for Emerging Viruses: Vaccines and Therapeutics |
| Autore | Rong Lijun |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (373 p.) |
| Soggetto topico |
Science: general issues
Medical microbiology & virology Microbiology (non-medical) |
| Soggetto non controllato |
Emerging viruses
antivirals inhibitors vaccines small molecules peptides antibody |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Antivirals for Emerging Viruses |
| Record Nr. | UNINA-9910557227103321 |
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Rong Lijun
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics
| Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics |
| Autore | Tutone Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (387 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
3D-QSAR
pharmacophore modeling ligand-based model HDACs isoform-selective histone deacetylase inhibitors aminophenylbenzamide hERG toxicity drug discovery fingerprints machine learning deep learning gene expression signature drug repositioning approaches RNA expression regulation high-throughput virtual screening dual-target lead discovery neurodegenerative disorders Alzheimer's disease dual mode of action multi-modal nicotinic acetylcholine receptor acetylcholinesterase molecular docking methotrexate drug resistance human dihydrofolate reductase virtual screening molecular dynamics simulation epitope binning epitope mapping epitope prediction antibody:antigen interactions protein docking glycoprotein D (gD) herpes simplex virus fusion proteins Src inhibitors pharmacophore model molecular dynamics simulations in silico COX-2 inhibitors molecular modeling sodium-glucose co-transporters 2 FimH uropathogenic bacteria urinary tract infections diabetes drug-resistance mutations HIV-2 protease structural characterization induced structural deformations SARS-CoV-2 COVID-19 multiprotein inhibiting natural compounds MD simulation 3CL-Pro antivirals docking simulations drug repurposing consensus models binding space isomeric space MRP4 SNPs variants protein threading modeling molecular dynamics binding site hTSPO PK11195 cholesterol homology modeling molecular dynamics (MD) simulation carbon nanotubes Stone-Wales defects haeckelite defects doxorubicin encapsulation drug delivery system binding free energies noncovalent interactions main protease mutants inhibitors PF-00835231 Mycobacterium tuberculosis tuberculosis proteasome natural compounds multiscale multitargeting polypharmacology computational biology drug repositioning structural bioinformatics proteomic signature skin aging oxidative stress aging progression mechanism genome-wide genetic and epigenetic network (GWGEN) systems medicine design multiple-molecule drug immunoproteasome non-covalent inhibitors MD binding metadynamics induced-fit docking |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Computational Approaches |
| Record Nr. | UNINA-9910557519403321 |
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Tutone Marco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Advances on Zika Virus Research
| New Advances on Zika Virus Research |
| Autore | Martinez-Sobrido Luis |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (552 p.) |
| Soggetto non controllato |
microRNAs
antivirals reverse genetics nucleic acid computation viral pathogenesis plaque reduction neutralization test clinical trials viral genetic variation viral fitness pregnancy type I IFN antagonist prM-E proteins eye replicon antiviral responses Bacterial artificial chromosome gene expression NS1 protein viral permissiveness ZIKV–host interactions reporter virus viral persistence blood-retinal barrier virus like particles emerging arbovirus Non-human primates heme-oxygenase 1 mosquito surveillance antiviral compounds ZIKV-associated neurologic disorders external quality assessment outbreak control therapeutics cryptic promoter silencing testis neurons mutagenesis RNA-seq microsphere immunoassay host-directed antivirals molecular diagnostics Bayesian analyses astrocytomas Full-length cDNA infectious clones viral pathogenicity neural progenitor cells full-length molecular clone antiviral multiplex nucleic acid detection Asian-lineage nucleic acid strand exchange IgA African-lineage vaccines Zika research models and tools immune response IgG avidity tests polymerase chain reaction Asian lineage sexual transmission TLR7/8 neuropathogenesis cross-reactions genetic variability mosquito ZIKV infectious cDNA prostate host genetic variation monoclonal antibodies optimised anti-viral immunity QCMD arbovirus FSS13025 MR766 NS5 EQA testicular cells virus attachment flavivirus mosquito-borne flavivirus dsRNA boolean logic-processing nucleic acid probes Ziks virus viral replication Aedes aegypti infection natural history infectious RNA zika virus chimeric viruses subgenomic replicon replication human brain glial cells microglia cells hepatocytes bacterial artificial chromosome detoxification and immune system responses testes dengue viruses Zika virus insecticide resistance NS2A protein plasmid toxicity cell surface receptors serology viral evolution laboratory preparedness flaviviruses Tet-inducible dengue virus diagnosis assay standardization infectious clone ELISA innate response congenital Zika syndrome secondary infections apoptosis viral survival ocular validated rhesus macaques neuroinflammation placenta cells NHP Zika virus (ZIKV) point-of-care diagnostics isothermal nucleic acid amplification microcephaly cytopathic effects indirect immunofluorescence fetal infection therapy siRNA viral counteraction neural cells silvestrol eIF4A |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346661103321 |
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Martinez-Sobrido Luis
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Insights into Parvovirus Research
| New Insights into Parvovirus Research |
| Autore | Gallinella Giorgio |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (342 p.) |
| Soggetto non controllato |
antivirals
Bombyx mori bidensovirus Bocaparvovirus human bocavirus 1 equine parvovirus-hepatitis NS2 NS1 X-ray crystallography BIRC3 (cIAP-2) glycans children antibody interactions new viruses alpaca cidofovir rodent protoparvoviruses clinical trials structural biology DNA virus human bocavirus caspase-3 viral communities uncoating PLA2 phospholipase-A2 oncolytic virus immune therapy Parvoviridae viral ecology Cryo-EM AAV metagenomics phylogeny oncolytic viruses mite parvovirus evolution Carnivore protoparvovirus 1 adeno-associated virus telbivudine capsid stability virus homology modeling human airway epithelia sequence analysis acute gastroenteritis bisulfite PCR next-generation sequencing single stranded DNA virus overlapping promoters virus diversity prognosis oncolytic activity genome hydroxyurea Lepidoptera genome externalization antiviral compounds circulating angiogenic cells tumor microenvironment coumarin derivatives nuclear targeting densovirus receptor interactions cell cycle arrest transcription profile brincidofovir canine parvovirus endogenous viral elements inflammatory cardiomyopathy erythroid progenitor cells RNA-seq insect chapparvovirus RT-qPCR trafficking AAV2 agricultural pests Adeno-associated virus myocarditis diagnosis parvovirus feline panleukopenia virus chitin B19V transcription mapping flavonoids immunomodulation erythrovirus apoptosis adenoviral vector anti-cancer divalent cations protease genetics preclinical arthropod peritrophins biocontrol dilated cardiomyopathy insect parvovirus combination therapies intravenous immunoglobulin (IVIG) virus phylogeny evolution second generation parvovirus treatments commercial horse serum parvovirus B19 canine chapparvovirus CpG methylation RACE H-1PV viral metagenomics horses |
| ISBN | 3-03928-311-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404088603321 |
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Gallinella Giorgio
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Therapies of Liver Diseases
| New Therapies of Liver Diseases |
| Autore | Toniutto Pierluigi |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (236 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
tolvaptan
cirrhotic ascites survival rate furosemide primary biliary cholangitis autoantibodies ursodeoxycholic acid treatment response second line therapy primary biliary cholangitis (PBC) primary sclerosing cholangitis (PSC) clinical trials ursodeoxycholic acid (UDCA) Farnesoid X Receptor (FXR) agonist Pan-Peroxisome Proliferator-Activated Receptor (PPAR) agonists liver cancer systemic treatment immunotherapy real-world unresectable hepatocellular carcinoma cirrhosis decompensation bleeding varices survival infection alcoholic hepatitis acute-on-chronic liver failure cholangiocarcinoma colorectal cancer metastases hepatocellular carcinoma liver transplantation Milan criteria alpha-fetoprotein solid organ transplantation liver injury immunosuppressant SARS-CoV-2 humoral response vaccination portal-systemic shunt ammonia vigilance HBV HDV antivirals functional cure pharmacology acute-on-chronic liver failure (ACLF) liver transplantation (LT) decompensated cirrhosis portal hypertension ascites non-selective beta-blockers TIPS rifaximin human albumin statins targeted therapy effective hypovolemia anti-mineralocorticoids loop diuretics vaptans |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566457403321 |
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Toniutto Pierluigi
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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