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Amide Bond Activation
| Amide Bond Activation |
| Autore | Szostak Michal |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (466 p.) |
| Soggetto non controllato |
N-heterocyclic carbene
non planar amide ruthenium (Ru) physical organic chemistry gemcitabine prodrug pyramidal amides bridged sultams catalysis dipeptides N-(1-naphthyl)acetamide C-N ? bond cleavage steric effects peptide bond cleavage transition-metal-free palladium N-heterocyclic carbenes (NHCs) addition reaction C–O activation rhodium metal complexes carbanions thioamidation amide bond intramolecular catalysis antiviral activity additivity principle pre-catalysts C–N bond cleavage bridged lactams C–H acidity arynes twisted amides organic synthesis amination Suzuki-Miyaura tert-butyl cyclopentadienyl complexes C-S formation enzymes DFT study sulfonamide bond N HERON reaction primaquine entropy amide activation amidation synthesis amide hydrolysis carbonylicity amide bond activation amide bond resonance aminosulfonylation molecular dynamics model compound in situ amide homogeneous catalysis heterocycles anomeric effect multi-component coupling reaction kinetic excited state C–H bond cleavage palladium catalysis amides thiourea formylation alkynes cis/trans isomerization amide C–N bond activation intein C-H functionalization succindiamide amide bonds crown ether aminoacylation directing groups cytostatic activity reaction thermodynamics acyl transfer transition metals N-dimethylformamide DMAc acylative cross-coupling C-H/C-N activation nickel catalysis antibacterial screening sodium aryl thioamides Winkler-Dunitz parameters catalyst N-dimethylacetamide base-catalyed hydrolysis nitrogen heterocycles cross-coupling insertion amidicity nitro-aci tautomerism activation carbonylation transamidation amine distortion Pd-catalysis rotational barrier energy hypersensitivity N–C activation metabolic stability [2+2+2] annulation twisted amide protease cyanation amide resonance trialkylborane catalysts biofilm eradication pharmacokinetics pancreatic cancer cells DMF aryl esters Michael acceptor fumardiamide water solvation ester bond activation cyclization nuclear magnetic resonance secondary amides reaction mechanism density functional theory density-functional theory amino acid transporters |
| ISBN | 3-03921-204-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346843703321 |
Szostak Michal
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antiviral Agents
| Antiviral Agents |
| Autore | Adamson Catherine |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (386 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Zika virus
nucleoside analogues antiviral agents NS5 prodrugs ProTides neural stem cells RNA-dependent RNA polymerase cytomegalovirus latent infection TALEN Surveyor nuclease mutation detection assay ie-1 gene quantitative real-time PCR Epstein-Barr virus herpes viruses lytic gene expression Burkitt lymphoma cells clozapine antipsychotic drug antiviral drug enteroviruses coxsackievirus B4 persistent infection fluoxetine resistance mutations herpes B virus macacine herpesvirus-1 genistein flavonoids acyclovir ganciclovir Plantago asiatica Clerodendrum trichotomum RSV therapeutic effects acteoside human antimicrobial peptides antiviral strategies defensins cathelicidins hepcidins transferrins influenza A virus brevilin A antiviral sesquiterpene lactone replication PRRSV polyethylenimine PEI virion internalization endocytosis HIV pediatrics Ethiopia pre-treatment drug resistance combination antiretroviral therapy (cART) dried plasma spots dried blood spots sphingolipids glycosphingolipids viruses lipid biosynthesis flavivirus Japanese encephalitis virus furin inhibitor precursor membrane protein measles virus central nervous system tropism treatments porcine reproductive and respiratory syndrome virus ginsenoside Rg1 antiviral activity pro-inflammatory factor NF-κB signaling pathway acute/latent infection congenital infection antiviral agent therapeutic strategies nucleic acid-based therapeutic approach HCMV vaccine adoptive cell therapy Rev response element chemical footprinting SHAPE drug discovery branched peptides herpesvirus immediate-early IE1 IE2 ribozyme RNA interference CRISPR/Cas small molecule orthohantavirus phenyl-benzotriazoles C-FRA Porcine circovirus type 2 epigallocatechin gallate heparan sulfate antiviral effect virus attachment microvirin lectin human immunodeficiency virus hepatitis C virus antiviral inhibitor non-immunogenic viral entry protein drugs LUMS1 oleanane-type derivatives influenza A virus (IAV) virus entry inhibitors hemagglutinin (HA) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557448703321 |
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Adamson Catherine
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactives and Functional Ingredients in Foods
| Bioactives and Functional Ingredients in Foods |
| Autore | Pacifico Severina |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (290 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
antioxidant effect
lectins nanoliposomes purity grade quercetin trans-aconitic acid anthocyanins antioxidant activity bioactive compounds colorants fruit juices polyphenols wild blueberry antidiabetic cardioprotective functional foods nutraceuticals okra phytotherapy Jamaican cherry fermentation Lactobacillus plantarum antioxidant food nutrition improvement okra mucilage okra polysaccharides biopolymer α-amylase activity α-glucosidase activity antidiabetic activity biodegradable edible film release pectin sodium caseinate oil oxidation waste biomass coffee Coffea arabica phenolic free-radical scavenging iron chelating cytotoxic plant secondary metabolites antiviral activity food noroviruses MNV FCV yogurt betalains encapsulation lyophilization ionizing radiation radioprotection flavonoids plant extracts oxidative stress zebrafish embryo carotenoids Trapa bispinosa Roxb polyphenol ellagitannin gallotannin α-glucosidase inhibitor advanced glycation end products (AGEs) antiglycation effect LC/UV/ESIMS analysis anti-diabetic abscisic acid Diabetes mellitus molecular docking phytohormones spray drying vegetable powders beetroot natural colorants violet betalain pigments bioactivity medicinal plants wild fruits industrial crops PCA HCA phenols TEAC roasting GAE |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595072703321 |
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Pacifico Severina
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Features of Pathogenesis of Human Viral Infections and Antiviral Drugs
| Features of Pathogenesis of Human Viral Infections and Antiviral Drugs |
| Autore | Aquaro Stefano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (84 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
hRSV
F gene G gene children respiratory diseases genotyping Saudi Arabia α chemokine receptor 4 β-chemokine receptor 5 human immunodeficiency virus monocyte-derived macrophages HPV sexually transmitted diseases (STDs) laboratory methods PCR genotypes surveillance epidemiology exopolysaccharides lactic acid bacteria human adenovirus type 5 antiviral activity cell cycle prevalence hepatitis B virus genotype bahrain sRAGE oxidative stress inflammation warts |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557135803321 |
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Aquaro Stefano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Venom and Toxin as Targeted Therapy
| Venom and Toxin as Targeted Therapy |
| Autore | Kwok Hang Fai (Henry) |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (180 p.) |
| Soggetto non controllato |
cane toad
B cell non-Hodgkin lymphoma Malaysian cobras complement system decay accelerating factor neuroblastoma atopic dermatitis complement dependent cytotoxicity antioxidant enzymes bacterial adhesion cancer therapy N. kaouthia anuran skin secretion frog Apis mellifera syriaca solid phase extraction bee venom phospholipase A2 (bvPLA2) disintegrin toad toxins immunotoxins ribosome-inactivating proteins antimicrobial peptide (AMP) drug design Moxetumomab pasudotox snake venom antiviral activity in vitro effects bombesin-related peptide oxidative stress biomarkers half-life blood vessel formation target therapy 2 MYCN indolealkylamines Huachansu membrane attack complex bouganin bee venom SEM anticancer activity antimicrobial peptide house dust mite extract (DFE) mannose receptor O. hannah bicarinalin gastric cells melittin LC-ESI-MS dermaseptin smooth muscle apoptosis anticancer N. sumatrana Helicobacter pylori inflammation immunotherapy atopic dermatitis (AD) immunotoxin mantle cell lymphoma clearance mass spectrometry Bougainvillea rRNA N-glycosylase activity fungal toxin skin inflammation targeted therapy 4-dinitrochlorobenzene (DNCB) Bee venom VEGF Chansu bufadienolides obsessive-compulsive disorder (OCD) BLF1 antimicrobial activity orellanine VB6-845 acute lymphoblastic leukemia ribosome-inactivating protein CD206 molecular cloning cancer CD22 eIF4A |
| ISBN | 3-03921-190-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367754703321 |
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Kwok Hang Fai (Henry)
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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