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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (606 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
1,2,3-triazole
2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide 3,6-dibromocarbazole 4-(pyridin-4-yloxy)benzamide 5-bromoindole 5-fluorouracil ABCB1 (P-glycoprotein) actin ADME allene amides/esters androgen receptor anti-cancer activity anti-neuroinflammation anti-ovarian cancer anti-tumor anticancer anticancer activity anticancer agent anticancer agents anticancer compounds antimitotic agents antioxidant activity antiproliferative activity antiproliferative agent antitumor antitumor activity apalutamide apoptosis aromatase benzimidazole benzofuran-pyrazole benzofurans beta-lapachone bivalency breast cancer c-Met carbazole cell cycle chemical synthesis chemoresistance chrysin analogues colchiceine colchicine amide colchicine analogs colchicine sulfonamide colon cancer computational docking coumarin crystal structure cyanopyridone cytotoxic activity cytotoxic properties cytotoxicity darolutamide DFT study dihydroartemisinin dihydropyranoindole docking docking studies drug discovery drug resistance E-stereoselective enzalutamide enzyme inhibition estrone derivatives flavonoid flavonoids gemcitabine HDAC inhibitors HeLa HepG2 hydrates hydrazine IGF-1R IL-12 immune modulation indoleamine 2,3-dioxygenase inflammation inhibitor K562 kinase inhibitor MCF-7 MDM2-p53 interaction migration mimetics molecular simulation MOLT-4 multidrug resistance (MDR) reversal N-substituted pyrazoline nanoparticles natural product neuroblastoma NIH3T3 o-nitro-benzyl organosilicon compounds ortho-quinones ovarian cancer overcoming drug resistance P-glycoprotein P-MAPA PARP inhibitor PARP-1 inhibition phenylpyrazolopyrimidine photoactivatable protecting groups PI3Ks PI3Kα inhibitor PI3Kδ inhibitors polyvalency prodrug prostate cancer PROTACs protein degradation protein kinase protein-protein interactions Pyrazole pyrazolopyridine pyridotriazine quinazolin-4(3H)-one quinazolin-4(3H)-thione regioselective salinomycin Schiff base SILA-409 (Alis-409) SILA-421 (Alis-421) Src substituted pyridine synergy synthesis Talazoparib tanshione IIA taxoids thiazolidinone Thienopyrimidine thienopyrimidinone thiocolchicine thiopene thioxotriazopyridine TLR signaling topoisomerase II inhibitor triazolothiadiazine triple-negative breast cancer tryptophan metabolism tubulin inhibitors tumor specificity urea virtual screening xanthones yeast-based assays zampanolide βIII-tubulin |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumor and Anti-HIV Agents from Natural Products
| Antitumor and Anti-HIV Agents from Natural Products |
| Autore | Nakagawa-Goto Kyoko |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (338 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
acute toxicity
allyl isothiocyanate Angelica dahurica anti-HIV antiangiogenic antioxidants antiproliferation antiproliferative activity antiretroviral agents antitumor activity apoptosis Artemisia absinthium L. aspidosperma-type benzyl isothiocyanate bladder cancer Bousigonia mekongensis BRAF inhibitor breast cancer butanolides caffeic acid cancer cancer multidrug resistance cancer stem cell Carpesium divaricatum cell cycle cell cycle arrest cervical cancer chemistry chemoprevention cisplatin coumarins curcumin analog cytotoxicity delcosine delpheline diterpenoid alkaloids DOTA drug development drug-drug interaction epithelial-to-mesenchymal transition essential oil flavonoids G2/M phase cell cycle arrest HaCaT cells HEF cell line hepatocellular carcinoma hepatoma cells Hernandia nymphaeifolia human tumor cell lines human tumor cells inflammation Ivalin kobusine lignan glycosides lipojesaconitine marine metabolites matrix metalloproteinase medicine melanoma melanoma and breast cancer cell line Mentha aquatica var. Kenting Water Mint metastasis mitochondria-mediated apoptosis monoterpenoid indole alkaloids natural agents natural phaeosphaeride A natural products NF-κB oral squamous cell carcinoma cells oxidative stress oxypeucedanin P-glycoprotein p53 phenethyl isothiocyanate phenolic acid pseudokobusine pterostilbene quercetin reactive oxygen species resveratrol SK-Hep-1 sulforaphane tamoxifen taxol total phenolic content transforming growth factor-β1 triterpenoids tubulin inhibitor tumor suppression two-stage skin carcinogenesis ursolic acid β-lapachone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557504803321 |
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Nakagawa-Goto Kyoko
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Compounds from Microbes
| Bioactive Compounds from Microbes |
| Autore | Katharina Riedel |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 online resource (142 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Microbiology (non-medical) |
| Soggetto non controllato |
antibiotics
antitumor activity food-encrypted peptides Gut Microbiota gut-brain axis human-microbes cross talk immune-system modulation Metabolomics Metagenomics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910220054303321 |
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Katharina Riedel
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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From Natural Polyphenols to Synthetic Bioactive Analogues
| From Natural Polyphenols to Synthetic Bioactive Analogues |
| Autore | Tringali Corrado |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (98 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
Alzheimer's disease
anti-inflammatory activity anti-oxidant activity antimicrobial activity antioxidant activity antitumor activity apoptosis aza-stilbene azo-stilbene bio-isosterism bisphenol neolignans cirsimaritin hispidulin honokiol isorhamnetin keratinocytes LC/MS-MS Melaleuca styphelioides multicomponent reactions n/a polyphenolics polyphenols structure-activity relationship Suzuki-Miyaura cross-coupling Tamarix ramosissima trans-resveratrol Ugi reaction β-amyloid proteins β-lactams |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557467903321 |
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Tringali Corrado
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Drug Research in China: Selected Papers from the 15-NASMD Conference
| Marine Drug Research in China: Selected Papers from the 15-NASMD Conference |
| Autore | Zhou Xuefeng |
| Descrizione fisica | 1 online resource (512 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
absolute configuration
AChE inhibitory actinomycete actinomycin D actinomycin X2 adenosine monophosphate-activated protein kinase (AMPK) ADME ADMET adsorption kinetics and isotherms angiotensin-I-converting enzyme (ACE) peptide Antarctic krill (Euphausia superba) anti-glioma activity anti-inflammatory activity antiaging antibacterial antibacterial activity antibacterial properties anticancer antihyperlipidemic antimicrobial activity antimicrobial peptides antioxidant activity antitumor activity antitumor peptide apoptosis Arca inflata aromatic acids ascidian-derived fungus Aspergillus flavipes HN4-13 Aspergillus hiratsukae Aspergillus puniceus Aspergillus sclerotiorum Aspergillus sp Aspergillus terreus Aspergillus unguis biological activities butenolides butyrolactone I Caenorhabditis elegans calmodulin CDK4/6 chejuenlide chronic kidney disease clavipitacae cognitive dysfunction colorectal cancer coral-derived fungi cyclic pentapeptide cytotoxic activity cytotoxicity deep-sea actinomycetes deep-sea fungus deep-sea-derived fungus depsides depsidones Diaporthe sp drug design dyeing emodin enantiomers endothelin-1 (ET-1) enrichment eremophilane sesquiterpenoids flavonoid fluorescent properties food allergy fucoidan fucoxanthin galaxamide analogues genome mining geodin GSK3β-Nrf2-HO-1 signaling Hahella heterocornols IL-17 pathway insecticidal activity isoquinoline alkaloid LC-MS/MS Lecanicillium fusisporum lipodepsipeptide macroporous resin XAD-16 mangrove endophytic Pestalotiopsis mangrove-derived fungus MAPK signaling marine compounds marine fungi mechanism meroterpenoids metabolism methicillin-resistant Staphylococcus aureus microbial pigments microbiota microglial polarization mm-pbsa molecular docking molecular dynamics mutants NAFLD nasopharyngeal carcinoma neuroinflammation nitric oxide (NO) Nrf2 nuclear factor erythroid-2-related factor 2-mediated (Nrf2) Oceanapia osteoclast differentiation oxidative stress oxidized low-density lipoprotein oximes oyster pancreatic lipase PD-L1 Penicillium sp peptide peptidome Pestalotiopsis heterocornis pharmacokinetics pharmacophore construction pharmacophore modeling phycocyanin piericidins plasma prodiginine protein tyrosine phosphatase inhibitor pyranodipyran derivatives sclerotides Sdy-1 secondary metabolites semisynthesize sesquiterpene glycoside signaling pathway silk skipjack tuna (Katsuwonus pelamis) muscle soft-coral-derived fungus Sonneratia apetala sponge sponge-derived fungus stability Streptomyces parvulus tetramic acid derivatives Toll-like receptor 4-mediated (TLR4) transcriptome Trichoderma longibrachiatum tyrosyl DNA phosphodiesterase 1 inhibitory activities vascular endothelial cell virtual screening Wnt signaling xanthones β-catenin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Marine Drug Research in China |
| Record Nr. | UNINA-9910595071903321 |
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Zhou Xuefeng
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| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases
| Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases |
| Autore | Rustum Youcef M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (166 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
anticancer
anticancer agent antitumor activity apoptosis cancer cancer stem cells cell plasticity chemotherapeutics clear cell renal cell carcinoma clear-cell renal cell carcinoma microRNAs disease DNA damage DNA damage and repair EMT entosis epigenetics ER stress glutathione head and neck cancer HIF hSP56 hypoxia hypoxia-inducible factor hypoxia-inducible factors (HIFs) immune evasion isoselenourea lipid peroxidation malignant melanoma methylseleninic acid methylselenocysteine methylselenoesters miRNA mTOR inhibitors PD-L1 radiation SBP1 Se-containing nanoparticles SELENBP1 selenium selenium species selenium-binding protein 1 seleno-l-methionine STAT3 tocopherol tumor heterogeneity tumor microenvironment VEGF viability |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346851003321 |
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Rustum Youcef M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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