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Glutathione: Chemistry and Biochemistry
| Glutathione: Chemistry and Biochemistry |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2023 |
| Descrizione fisica | 1 online resource (212 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
angiotensin-converting enzyme
anticancer drugs apoptosis autoimmune diseases bioactivation brain cell cell injury chalcone cyclophosphamide cysteine detoxification DFT diastereoselective addition diode array detector endothelial cells fluorescence probes GCLc glutaredoxin glutathione glutathione enzyme glutathione system glutathione-S-transferase glutathionylation GSH GSS GSSG iron iron-sulfur cluster ischemia liquid chromatography M06-2X/6-311++G(d,p) mechanisms of glutathione conjugation reaction Michael addition molecular docking n/a nanotoxicity nitrosoglutathione oxidative stress pharmacokinetics physicochemical properties polymerized whey protein polymorphism reactive oxygen species redox homeostasis redox potential redox-regulation S-glutathionylation S-nitrosylation sulodexide supramolecular arrangement thiols toxicity |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Glutathione |
| Record Nr. | UNINA-9910743269903321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ionic Liquids and Deep Eutectic Solvents for Application in Pharmaceutics
| Ionic Liquids and Deep Eutectic Solvents for Application in Pharmaceutics |
| Autore | Branco Luis Cobra |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (154 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
Active Pharmaceutical Ingredients
active pharmaceutical ingredients as organic salts and ionic liquids (API-OSILs) active pharmaceutical ingredients-ionic liquids and organic salts (API-OSILs) alendronic acid antibiotics anticancer drugs anticrystal engineering API-OSILs benzocaine biocompatible chemical ciprofloxacin deep eutectic mixtures drug absorption drug delivery fluoroquinolones ionic liquid ionic liquids ketoprofen lipid formulation classification system lipid-based formulation lipophilic salt local anesthetics lumefantrine mechanochemistry microemulsion n/a non-steroidal anti-inflammatory drugs (NSAIDs) norfloxacin penicillin G and amoxicillin hydrolysate derivatives permeation enhancer physical polymorphism poorly water-soluble drug procaine resistant bacteria SEDDS sensitive bacteria synergy tetracaine transdermal transdermal drug delivery system Transdermal drug delivery systems |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557780303321 |
Branco Luis Cobra
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metal-Based Drugs: Past, Present and Future
| Metal-Based Drugs: Past, Present and Future |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2023 |
| Descrizione fisica | 1 online resource (328 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
3D cell cultures
anti-bacterial compounds antibacterial activity antibiotics anticancer activity anticancer agents anticancer drugs antimicrobial activity antiparasitic apoptosis auxotrophy bioorganometallic biotin breast cancer cancer cancer research carbohydrates caspases chitosan chlorophyllides cis and trans-Pt(II) coordination complexes copper copper(II) complexes CuAAC reactions delivery electronic spectra fluoxetine HCl FTIR gabapentin gallium gold gold compounds green synthesis heterobimetallic complexes human foreskin fibroblasts interactions lanthanum liposomes loading efficacy major depressive disorder MCF-7 MDA-MB-231 metal complexes metal-based drugs microarray-based detection molecular docking nanoparticles NHC silver complexes NHCs properties oncology orphan tumors platinum platinum (II) complexes platinum (IV) complexes platinum compounds Pseudomonas alloputida resistance phenomena ROS Rubus ruthenium ruthenium(II)-arene complexes ruthenium(III) complexes serum proteins silver spectroscopic spectroscopy structure activity relationships (SAR) synergy targeting strategies TEM thermodynamic analysis toxicity Toxoplasma gondii transition metals zinc oxide π-acceptor complexes |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Metal-Based Drugs |
| Record Nr. | UNINA-9911053220603321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers
| Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers |
| Autore | Kutner Andrzej |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (450 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
1,2,4-triazole
25 vitamin D 24-hydroxylase A-ring active substance delivery systems active substance-controlled release ADME alkaloids alpha-ketoglutarate analogue actions at genes anti-depressant therapy anti-inflammatory activity anticancer activity anticancer drug anticancer drugs antidepressants antimalarial antimicrobial activity antimicrobial compounds antimicrobial peptide (AMP) antioxidant activity antiparasitic agents antiviral proteins apoptosis Au(III) complex biomarker biomedical hydrogels calcilytic calcimimetic calcium-sensing receptor cancer cancer cells cancer therapy cancer treatment CD-ring cell cycle cell invasion cell migration Chelidonium majus ChIP-chip analysis colon cancer colorectal cancer copper (II) complexes CRISPR/Cas9 cyclooxygenase CYP24A1 CYP24A1-dependent metabolism CYP27B1 cytotoxic activity cytotoxic study cytotoxicity defense-related proteins depression dermaseptin distal enhancers drug drug design drug design and discovery drug discovery dual 5-HT1A/SERT activity electrochemistry enantiomer fluorine frog skin peptides genistein genome editing glucose metabolism glycoconjugates gold gold electrode greater celandine hemolysis high-grade serous ovarian cancer cells histone deacetylase (HDAC) histone H3 acetylation HT-29 human DNA topoisomerase hydrogels for cosmetology hydrogels for dermatology IL-8 inflammation JNK latex LHRH lung cancer major latex protein MALDI metabolite metallodrugs methotrexate molecular docking molecular modeling multimodal activity n/a nanoparticles organometallic oxidation mechanisms Phyllomedusa bicolor Plasmodium falciparum (P. falciparum) PRI-2191 proliferation prostate cancer proteome analysis pyridazinone pyrido[1,2-c]pyrimidines resveratrol rickets RNA polymerase II SAR self-assembled monolayer side-chain spectroscopic data split luciferase-based biosensor stereospecificity synthesis targeted therapy tetrahydro-β-carbolines TGF-β therapeutic peptides thiourea transcription transdermal active substance delivery systems VEGF vitamin D vitamin D analogs vitamin D biology and action vitamin D hormone (1,25(OH)2D3) vitamin D receptor vitamin D3 Warburg effect |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585938903321 |
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Kutner Andrzej
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers 2.0
| Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers 2.0 |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2023 |
| Descrizione fisica | 1 online resource (494 p.) |
| Soggetto topico | Medical equipment and techniques |
| Soggetto non controllato |
activity profiling, markers and diagnostics
antibiotics anticancer drugs antimicrobial drugs antiviral drugs cancer prevention crystallography dissolution testing dosage form drug carriers drug design and discovery drug response drug solubility drug&ndash molecular mechanisms molecular modeling nanoparticles nuclear receptors pharmacodynamics pharmacognosy pharmacokinetics preclinical study protein interactions receptor agonist and antagonist |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9911053039803321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plasma in Cancer Treatment
| Plasma in Cancer Treatment |
| Autore | Bogaerts Annemie |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (358 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
anticancer drugs
apoptosis bone cancer breast cancer cancer cancer selectivity cell adhesion cell communication cellular uptake cervical cancer treatment cervical intraepithelial neoplasia cervical intraepithelial neoplasia (CIN) cholangiocarcinoma cold atmospheric plasma cold atmospheric plasma (CAP) cold atmospheric pressure plasma cold physical plasma cold plasma combination therapy communication junctions cytotoxicity dendritic cells dielectric barrier discharge DNA-damage electric pulses electroporation extracellular matrix (ECM) extracellular vesicles free radicals genome-wide expression gold quantum dots high frequency electrosurgery human glioblastoma immunogenic cell death indirect treatment innovative therapy invasiveness kINPen long-lived reactive oxygen and nitrogen species long-lived reactive species macrophages melanoma multicellular tumor spheroids n/a nanomaterials non-invasive plasma treatment (NIPP) non-thermal atmospheric pressure plasma (NTP) non-thermal plasma nonthermal biocompatible plasma olaparib oncology organotypic model osteosarcoma ovarian cancer p38/MAPK pathway pancreatic cancer pancreatic stellate cells PARP-inhibitor plasma plasma jet Plasma lipid interactions plasma medicine plasma selectivity plasma treatment plasma-activated liquid plasma-activated liquids plasma-activated Ringer's lactate solution plasma-treated liquid plasma-treated phosphate-buffered saline pulsed electric field amplitude radiation therapy radio-frequency discharge Raman imaging Raman microspectroscopy reactive oxygen and nitrogen species reactive oxygen and nitrogen species (ROS) reactive oxygen species reactive species Ringer's saline ROS screening selectivity soft jet plasma three-dimensional in vitro culture models tissue penetration tumor cells tumor spheroids tumour microenvironment (TME) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557527603321 |
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Bogaerts Annemie
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Progress in Solid Dispersion Technology / Kohsaku Kawakami
| Recent Progress in Solid Dispersion Technology / Kohsaku Kawakami |
| Autore | Kawakami Kohsaku |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
thermodynamic modeling
molecular dynamics simulation poorly soluble drugs amorphous solid dispersions dissolution enhancement crystallization tendency continuous processing stability milling granulation thermal analysis amorphous ball milling pharmaceutical glass dissolution rebamipide poloxamer classification polyelectrolytes amorphisation self-assembly dissolution rate miscibility bioavailability solubility evaporation mesoporous polyelectrolyte excipient matrix polymer bicaludamide phase diagram Weibull dissolution model spectroscopic techniques anticancer drugs manufacturing methods nucleation molecular complex nanoaggregates enrofloxacin accelerated stability test solubility enhancement amorphous solid dispersion tadalafil process development amorphous polymeric salt Wood’s apparatus hot melt extrusion solid dispersions intrinsic dissolution rate solid dispersion interaction crystallization spray drying characterization ciprofloxacin |
| ISBN |
9783039215027
3039215027 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756203321 |
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Kawakami Kohsaku
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Natural Bioactive Compounds in the Rise and Fall of Cancers : Volume 2
| Role of Natural Bioactive Compounds in the Rise and Fall of Cancers : Volume 2 |
| Autore | Luparello Claudio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (318 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
acute myeloid leukemia
adipocyte inflammation AKT AMPK angiogenesis anti-cancer drug anti-proliferative anticancer anticancer activities anticancer drug anticancer drugs AOM/DSS model apoptosis autophagy berberine Berthel bioactivities bioavailability brain cancer breast cancer breast cancer cells breast cancer prognostic breast cancer risk Calocedrus formosana cancer cancer metabolism cancer stem cell cancer therapy carrageenan caspase-independent cell death cell death cell signaling cell-cycle arrest chemoprevention colchicine alkaloid colon cancer colon cancer cells colorectal cancer daidzein daidzein metabolites drugs EGCG EGFR signaling EGFR TKI eicosapentaenoic acid epigallocatechin-3-gallate (EGCG) epithelial mesenchymal transition ER stress estrogen estrogen receptor alpha ethanol experimental therapeutics FASN inhibitors flavonoids formononetin fucoidan G2/M arrest gallic acid gemcitabine gigantol gliomas glucose transport glycolysis glycolytic markers HDAC HO-1 honokiol human cancer cells immunotherapy inflammation innate immunity invasion isobolography isorhamnetin JAK/STAT lung cancer malignant cancer malignant tumors of the peripheral nerve sheath (MPNST) Malva pseudolavatera Webb & mangrove marine sponge mechanism melanoma cells mesoporous silica nanoparticles metastasis microRNAs MMPs molecular mechanisms multiple myeloma n/a nanoparticle-based delivery systems natural anti-inflammatory compounds natural bioactive compound natural compounds natural polyphenols natural product neurofibromas nicotine nobiletin non-coding RNAs Nrf2 NSCLC nutrition obesity oleacein oleuropein olive leaf extract oncogenic cascades oral cancer inhibition p53 paclitaxel pancreatic cancer PD-1 immune checkpoint inhibitor and cancer immunotherapy PD-L1 persistent organic pollutants phosphofructokinase phytochemicals Piper eriopodon, alkenylphenols polyphenols preclinical models pro-resolving lipids proteomics RacGAP1 radiotherapy reactive oxygen species renin-angiotensin system resistance ROS schwannomas Seahorse analysis signaling pathways signalling pathway small organic agents STAT3 Streptomyces systematic review targeted delivery system TRAIL tumor density tumor maintenance uterine sarcoma xenograft Xenopus laevis XIAP antagonists XIAP-BIR3 domain yatein α9-nAChR β-glucans |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Role of Natural Bioactive Compounds in the Rise and Fall of Cancers |
| Record Nr. | UNINA-9910557476303321 |
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Luparello Claudio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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